A Wells

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Epidermal growth factor receptor-mediated motility in fibroblasts
    A Wells
    Department of Pathology, University of Alabama at Birmingham, and Birmingham VA Medical Center, 35294 0007, USA
    Microsc Res Tech 43:395-411. 1998
  2. ncbi request reprint EGF receptor
    A Wells
    Department of Pathology, University of Alabama, Birmingham 35294 0007, USA
    Int J Biochem Cell Biol 31:637-43. 1999
  3. ncbi request reprint Tumor invasion as dysregulated cell motility
    J Kassis
    Department of Pathology, University of Pittsburgh and Pittsburgh VAMC, 713 Scaife Hall, Pittsburgh, PA 15261, USA
    Semin Cancer Biol 11:105-17. 2001
  4. pmc Epidermal growth factor (EGF)-like repeats of human tenascin-C as ligands for EGF receptor
    C S Swindle
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Cell Biol 154:459-68. 2001
  5. pmc Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin
    C C Yates
    Department of Pathology, University of Pittsburgh, Pittsburgh VAMC, PA 15213, USA
    Br J Cancer 96:1246-52. 2007
  6. pmc Luteinising hormone-releasing hormone analogue reverses the cell adhesion profile of EGFR overexpressing DU-145 human prostate carcinoma subline
    C Yates
    Department of Pathology, University of Pittsburgh, and Pittsburgh VAMC, Pittsburgh, PA 15261, USA
    Br J Cancer 92:366-75. 2005
  7. ncbi request reprint Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling
    A Glading
    Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Biol Chem 276:23341-8. 2001
  8. ncbi request reprint A role for phospholipase C-gamma-mediated signaling in tumor cell invasion
    J Kassis
    Birmingham Veterans Administration Medical Center, Department of Pathology, University of Alabama at Birmingham, 35294 0007, USA
    Clin Cancer Res 5:2251-60. 1999
  9. ncbi request reprint PLC gamma contributes to metastasis of in situ-occurring mammary and prostate tumors
    C R Shepard
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Oncogene 26:3020-6. 2007
  10. ncbi request reprint Kinetic and spectroscopic evidence for three actomyosin:ADP states in smooth muscle
    S S Rosenfeld
    Department of Neurology, University of Alabama at Birmingham, 35294, USA
    J Biol Chem 275:25418-26. 2000

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Epidermal growth factor receptor-mediated motility in fibroblasts
    A Wells
    Department of Pathology, University of Alabama at Birmingham, and Birmingham VA Medical Center, 35294 0007, USA
    Microsc Res Tech 43:395-411. 1998
    ..Our model postulates that many biochemical pathways will be shared between chemokinetic and haptokinetic motility but that select pathways will be activated only during RPTK-enhanced motility...
  2. ncbi request reprint EGF receptor
    A Wells
    Department of Pathology, University of Alabama, Birmingham 35294 0007, USA
    Int J Biochem Cell Biol 31:637-43. 1999
    ..Thus, EGFR and its downstream signaling molecules' are targets for therapeutic interventions in wound repair and cancer...
  3. ncbi request reprint Tumor invasion as dysregulated cell motility
    J Kassis
    Department of Pathology, University of Pittsburgh and Pittsburgh VAMC, 713 Scaife Hall, Pittsburgh, PA 15261, USA
    Semin Cancer Biol 11:105-17. 2001
    ....
  4. pmc Epidermal growth factor (EGF)-like repeats of human tenascin-C as ligands for EGF receptor
    C S Swindle
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Cell Biol 154:459-68. 2001
    ..These data identify a new class of "insoluble" growth factor ligands and a novel mode of activation for growth factor receptors...
  5. pmc Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin
    C C Yates
    Department of Pathology, University of Pittsburgh, Pittsburgh VAMC, PA 15213, USA
    Br J Cancer 96:1246-52. 2007
    ..We conclude that the term epithelial-mesenchymal transition only summarises the transient downregulation of E-cadherin for invasion with re-expression of E-cadherin being a physiological consequence of metastatic seeding...
  6. pmc Luteinising hormone-releasing hormone analogue reverses the cell adhesion profile of EGFR overexpressing DU-145 human prostate carcinoma subline
    C Yates
    Department of Pathology, University of Pittsburgh, and Pittsburgh VAMC, Pittsburgh, PA 15261, USA
    Br J Cancer 92:366-75. 2005
    ..The ability of Cetrorelix to downregulate EGFR signalling and subsequently reverse the antiadhesiveness found in metastatic prostate cancer highlights a novel potential target for therapeutic strategies...
  7. ncbi request reprint Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling
    A Glading
    Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Biol Chem 276:23341-8. 2001
    ....
  8. ncbi request reprint A role for phospholipase C-gamma-mediated signaling in tumor cell invasion
    J Kassis
    Birmingham Veterans Administration Medical Center, Department of Pathology, University of Alabama at Birmingham, 35294 0007, USA
    Clin Cancer Res 5:2251-60. 1999
    ..In all situations, the inhibition of PLCgamma signaling did not decrease mitogenic signaling. Thus, the motility-associated PLCgamma signaling pathway is a generalizable rate-limiting step for tumor cell progression...
  9. ncbi request reprint PLC gamma contributes to metastasis of in situ-occurring mammary and prostate tumors
    C R Shepard
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Oncogene 26:3020-6. 2007
    ..In conclusion, abrogation of the PLCgamma signaling pathway can limit the metastatic potential of carcinomas...
  10. ncbi request reprint Kinetic and spectroscopic evidence for three actomyosin:ADP states in smooth muscle
    S S Rosenfeld
    Department of Neurology, University of Alabama at Birmingham, 35294, USA
    J Biol Chem 275:25418-26. 2000
    ....
  11. ncbi request reprint Cytokine mRNA expression and serum cortisol evaluation during murine lung inflammation induced by Mycobacterium tuberculosis
    J K Actor
    Department of Pathology, University of Texas Houston Medical School, Texas 77030, USA
    Comb Chem High Throughput Screen 3:343-51. 2000
    ..The high constitutive serum cortisol in the A/J mice may therefore contribute to establishment of an environment counter-productive to initiation of protective Th1 cell and granulomatous responses...