Affiliation: University of Wisconsin
- Morphological and extracellular matrix changes following vocal fold injury in miceMasaru Yamashita
Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
Cells Tissues Organs 192:262-71. 2010..Morphological and ECM changes following vocal fold injury in the mouse were generally consistent with those reported in other animal models, particularly the rat, although wound repair in the mouse appears to occur at a faster rate...
- TGF-β3 modulates the inflammatory environment and reduces scar formation following vocal fold mucosal injury in ratsZhen Chang
Department of Surgery, Division of Otolaryngology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
Dis Model Mech 7:83-91. 2014..These experiments show that the TGF-β isoforms have distinct roles in VFM maintenance and repair, and that TGF-β3 redirects wound healing to improve VFM scar outcomes in vivo. ..
- Proteomic analysis of a decellularized human vocal fold mucosa scaffold using 2D electrophoresis and high-resolution mass spectrometryNathan V Welham
Division of Otolaryngology, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
Biomaterials 34:669-76. 2013..This work has implications for the manufacturing of biologic scaffolds from any tissue or organ, as well as for prediction and monitoring of the scaffold-host interaction in vivo...
- A rat excised larynx model of vocal fold scarNathan V Welham
University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
J Speech Lang Hear Res 52:1008-20. 2009..To develop and evaluate a rat excised larynx model for the measurement of acoustic, aerodynamic, and vocal fold vibratory changes resulting from vocal fold scar...
- Prospective multi-arm evaluation of surgical treatments for vocal fold scar and pathologic sulcus vocalisNathan V Welham
Division of Otolaryngology, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison Wisconsin, USA
Laryngoscope 121:1252-60. 2011..The purpose of this study was to compare the clinical effectiveness of type I thyroplasty, injection laryngoplasty, and graft implantation for the treatment of vocal fold scar and pathologic sulcus vocalis...
- Fibronectin and adhesion molecules on canine scarred vocal foldsShigeru Hirano
Department of Surgery, University of Wisconsin Madison, 53792, USA
Laryngoscope 113:966-72. 2003..To examine the expressions of fibronectin and other adhesion molecules on the scarred vocal folds in a short- and long-term animal model...
- Prevention of vocal fold scarring by topical injection of hepatocyte growth factor in a rabbit modelShigeru Hirano
Department of Bronchoesophagology, Kyoto National Hospital, Kyoto, Japan
Laryngoscope 114:548-56. 2004..The present study aimed to demonstrate the effects of HGF on vocal fold scarring in an in vivo rabbit model...
- Regeneration of Multi-layered Vocal Fold MucosaNathan Welham; Fiscal Year: 2010..The proposed research is focused on the optimization of a multi-layered vocal fold mucosa substitute for the treatment of diseased or damaged tissue, and restoration of vocal function. ..
- Proteomic Profiling of the Vocal Fold Extracellular MatrixNathan Welham; Fiscal Year: 2007..This project will also result in the development of a blueprint for the engineering of a healthy protein matrix for restoring damaged vocal folds. ..