Piri Welcsh

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Inherited breast cancer: an emerging picture
    P L Welcsh
    Department of Medicine, University of Washington, Seattle 98105, USA
    Clin Genet 54:447-58. 1998
  2. ncbi request reprint Insights into the functions of BRCA1 and BRCA2
    P L Welcsh
    Departments of Medicine and Genetics, Box 357720, University of Washington, Seattle, WA 98195 7720, USA
    Trends Genet 16:69-74. 2000
  3. ncbi request reprint BRCA1 and BRCA2 and the genetics of breast and ovarian cancer
    P L Welcsh
    Departments of Medicine and Genetics, Box 357720, University of Washington, Seattle, WA 98195 7720, USA
    Hum Mol Genet 10:705-13. 2001
  4. pmc Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene
    Brandon J Thomas
    Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, 815 Mercer St, Seattle, WA 98109, USA
    Epigenetics Chromatin 4:14. 2011
  5. doi request reprint 53BP1 expression in sporadic and inherited ovarian carcinoma: Relationship to genetic status and clinical outcomes
    Kathryn P Pennington
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA
    Gynecol Oncol 128:493-9. 2013
  6. doi request reprint E2F3b over-expression in ovarian carcinomas and in BRCA1 haploinsufficient fallopian tube epithelium
    Na Lu Smith
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, 98195, USA
    Genes Chromosomes Cancer 51:1054-62. 2012
  7. pmc Methylation and protein expression of DNA repair genes: association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomas
    Elizabeth M Swisher
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA
    Mol Cancer 8:48. 2009
  8. pmc Identification of a preneoplastic gene expression profile in tubal epithelium of BRCA1 mutation carriers
    Joshua Z Press
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA
    Neoplasia 12:993-1002. 2010
  9. pmc Angiogenic alterations associated with circulating neoplastic DNA in ovarian carcinoma
    Tilley Jenkins Vogel
    Department of Obstetrics and Gynecology, University of Washington, Seattle, WA
    Transl Oncol 5:247-51. 2012
  10. ncbi request reprint Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population
    Avraham Shaag
    Department of Medicine Medical Genetics and Genome Sciences, University of Washington, Seattle, WA 98195 7720, USA
    Hum Mol Genet 14:555-63. 2005

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Inherited breast cancer: an emerging picture
    P L Welcsh
    Department of Medicine, University of Washington, Seattle 98105, USA
    Clin Genet 54:447-58. 1998
    ....
  2. ncbi request reprint Insights into the functions of BRCA1 and BRCA2
    P L Welcsh
    Departments of Medicine and Genetics, Box 357720, University of Washington, Seattle, WA 98195 7720, USA
    Trends Genet 16:69-74. 2000
    ..Why do ubiquitously expressed genes that participate in universal pathways lead, when mutant, specifically to breast and ovarian cancer? Why are the same genes required for embryonic proliferation and for tumor suppression?..
  3. ncbi request reprint BRCA1 and BRCA2 and the genetics of breast and ovarian cancer
    P L Welcsh
    Departments of Medicine and Genetics, Box 357720, University of Washington, Seattle, WA 98195 7720, USA
    Hum Mol Genet 10:705-13. 2001
    ..Central to this model of BRCA-mediated tumorigenesis are estrogen-mediated proliferation of breast and ovarian epithelium and the distinctive genomic context of the BRCA genes...
  4. pmc Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene
    Brandon J Thomas
    Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, 815 Mercer St, Seattle, WA 98109, USA
    Epigenetics Chromatin 4:14. 2011
    ..abstract:..
  5. doi request reprint 53BP1 expression in sporadic and inherited ovarian carcinoma: Relationship to genetic status and clinical outcomes
    Kathryn P Pennington
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA
    Gynecol Oncol 128:493-9. 2013
    ..We characterized 53BP1 and BRCA1 expression and their association with clinical outcomes in sporadic and inherited ovarian carcinomas...
  6. doi request reprint E2F3b over-expression in ovarian carcinomas and in BRCA1 haploinsufficient fallopian tube epithelium
    Na Lu Smith
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, 98195, USA
    Genes Chromosomes Cancer 51:1054-62. 2012
    ..These data support that E2F3b up-regulation is an important preneoplastic event in FTE from BRCA1 mutation carriers...
  7. pmc Methylation and protein expression of DNA repair genes: association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomas
    Elizabeth M Swisher
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA
    Mol Cancer 8:48. 2009
    ..Additionally, we assessed whether promoter methylation of BRCA1, MLH1 or FANCF influenced response to chemotherapy or explained alterations in protein expression after chemotherapy exposure...
  8. pmc Identification of a preneoplastic gene expression profile in tubal epithelium of BRCA1 mutation carriers
    Joshua Z Press
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA
    Neoplasia 12:993-1002. 2010
    ..The expression of a subset of genes was validated with quantitative reverse transcription-polymerase chain reaction and immunohistochemistry...
  9. pmc Angiogenic alterations associated with circulating neoplastic DNA in ovarian carcinoma
    Tilley Jenkins Vogel
    Department of Obstetrics and Gynecology, University of Washington, Seattle, WA
    Transl Oncol 5:247-51. 2012
    ..Angiogenesis is critical in neoplastic growth and metastasis. We sought to determine whether circulating neoplastic DNA results from alterations in the balance of angiogenesis activators and inhibitors...
  10. ncbi request reprint Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population
    Avraham Shaag
    Department of Medicine Medical Genetics and Genome Sciences, University of Washington, Seattle, WA 98195 7720, USA
    Hum Mol Genet 14:555-63. 2005
    ....