Christine L Weisshaar

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc The potential for salmon fibrin and thrombin to mitigate pain subsequent to cervical nerve root injury
    Christine L Weisshaar
    Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104 6321, USA
    Biomaterials 32:9738-46. 2011
  2. doi request reprint ProDisc cervical arthroplasty does not alter facet joint contact pressure during lateral bending or axial torsion
    Nicolas V Jaumard
    Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    Spine (Phila Pa 1976) 38:E84-93. 2013
  3. ncbi request reprint Brain-derived neurotrophic factor is upregulated in the cervical dorsal root ganglia and spinal cord and contributes to the maintenance of pain from facet joint injury in the rat
    Jeffrey V Kras
    Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania
    J Neurosci Res 91:1312-21. 2013
  4. pmc Spinal neuronal plasticity is evident within 1 day after a painful cervical facet joint injury
    Nathan D Crosby
    Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104 6321, United States
    Neurosci Lett 542:102-6. 2013
  5. doi request reprint Facet joint contact pressure is not significantly affected by ProDisc cervical disc arthroplasty in sagittal bending: a single-level cadaveric study
    Joel A Bauman
    Department of Neurosurgery, 3 Silverstein Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
    Spine J 12:949-59. 2012
  6. doi request reprint Metabotropic glutamate receptor-5 and protein kinase C-epsilon increase in dorsal root ganglion neurons and spinal glial activation in an adolescent rat model of painful neck injury
    Christine L Weisshaar
    Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Neurotrauma 27:2261-71. 2010
  7. ncbi request reprint Superparamagnetic iron oxide-enhanced magnetic resonance imaging of neuroinflammation in a rat model of radicular pain
    Daniel L J Thorek
    Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA
    Mol Imaging 10:206-14. 2011
  8. ncbi request reprint Contact pressure in the facet joint during sagittal bending of the cadaveric cervical spine
    Nicolas V Jaumard
    J Biomech Eng 133:071004. 2011
  9. pmc Cytokine mRNA expression in painful radiculopathy
    Sarah M Rothman
    Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6321, USA
    J Pain 10:90-9. 2009
  10. pmc Salmon and human thrombin differentially regulate radicular pain, glial-induced inflammation and spinal neuronal excitability through protease-activated receptor-1
    Jenell R Smith
    Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 8:e80006. 2013

Collaborators

Detail Information

Publications11

  1. pmc The potential for salmon fibrin and thrombin to mitigate pain subsequent to cervical nerve root injury
    Christine L Weisshaar
    Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104 6321, USA
    Biomaterials 32:9738-46. 2011
    ..0001) but was unchanged from injury responses for thrombin treatment. Results suggest that salmon fibrin and thrombin may be suitable biomaterials to mitigate pain...
  2. doi request reprint ProDisc cervical arthroplasty does not alter facet joint contact pressure during lateral bending or axial torsion
    Nicolas V Jaumard
    Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    Spine (Phila Pa 1976) 38:E84-93. 2013
    ..A biomechanical study of facet joint pressure after total disc replacement using cadaveric human cervical spines during lateral bending and axial torsion...
  3. ncbi request reprint Brain-derived neurotrophic factor is upregulated in the cervical dorsal root ganglia and spinal cord and contributes to the maintenance of pain from facet joint injury in the rat
    Jeffrey V Kras
    Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania
    J Neurosci Res 91:1312-21. 2013
    ....
  4. pmc Spinal neuronal plasticity is evident within 1 day after a painful cervical facet joint injury
    Nathan D Crosby
    Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104 6321, United States
    Neurosci Lett 542:102-6. 2013
    ....
  5. doi request reprint Facet joint contact pressure is not significantly affected by ProDisc cervical disc arthroplasty in sagittal bending: a single-level cadaveric study
    Joel A Bauman
    Department of Neurosurgery, 3 Silverstein Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
    Spine J 12:949-59. 2012
    ..However, the effects of disc arthroplasty on facet joint biomechanics remain undefined despite the critical role of these posterior elements on guiding and limiting spinal motion...
  6. doi request reprint Metabotropic glutamate receptor-5 and protein kinase C-epsilon increase in dorsal root ganglion neurons and spinal glial activation in an adolescent rat model of painful neck injury
    Christine L Weisshaar
    Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Neurotrauma 27:2261-71. 2010
    ..These results suggest that adolescents may have a lower tissue tolerance to induce pain and associated nociceptive response than do adults...
  7. ncbi request reprint Superparamagnetic iron oxide-enhanced magnetic resonance imaging of neuroinflammation in a rat model of radicular pain
    Daniel L J Thorek
    Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA
    Mol Imaging 10:206-14. 2011
    ..These findings suggest that SPIO-enhanced MRI may be a valuable tool to identify otherwise undetectable nerve root compression and enable improved patient management...
  8. ncbi request reprint Contact pressure in the facet joint during sagittal bending of the cadaveric cervical spine
    Nicolas V Jaumard
    J Biomech Eng 133:071004. 2011
    ..This study shows that cervical facet contact pressure can be directly measured with minimal disruption to the joint and is the first to provide local pressure values for the cervical joint in a cadaveric model...
  9. pmc Cytokine mRNA expression in painful radiculopathy
    Sarah M Rothman
    Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6321, USA
    J Pain 10:90-9. 2009
    ....
  10. pmc Salmon and human thrombin differentially regulate radicular pain, glial-induced inflammation and spinal neuronal excitability through protease-activated receptor-1
    Jenell R Smith
    Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 8:e80006. 2013
    ..These results are the first to demonstrate that salmon thrombin has unique analgesic, neuroprotective and anti-inflammatory capabilities compared to human thrombin and that PAR1 may contribute to these actions. ..
  11. pmc Ablating spinal NK1-bearing neurons eliminates the development of pain and reduces spinal neuronal hyperexcitability and inflammation from mechanical joint injury in the rat
    Christine L Weisshaar
    Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania
    J Pain 15:378-86. 2014
    ..These results suggest that spinal NK1R-bearing cells are critical in initiating spinal nociception and inflammation associated with a painful mechanical joint injury...