John Weiss

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Ca permeable AMPA channels in diseases of the nervous system
    John H Weiss
    Department of Neurology, University of California Irvine Irvine, CA, USA
    Front Mol Neurosci 4:42. 2011
  2. pmc Slow development of ALS-like spinal cord pathology in mutant valosin-containing protein gene knock-in mice
    H Z Yin
    Department of Neurology, University of California, Irvine, CA 92697 4292, USA
    Cell Death Dis 3:e374. 2012
  3. pmc Mechanisms of rapid reactive oxygen species generation in response to cytosolic ca(2+) or zn(2+) loads in cortical neurons
    Aaron Clausen
    Department of Neurology, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 8:e83347. 2013
  4. pmc Cancer stem cells from a rare form of glioblastoma multiforme involving the neurogenic ventricular wall
    Shengwen Calvin Li
    Neuro Oncology Research Laboratory, Center for Neuroscience and Stem Cell Research, Children s Hospital of Orange County CHOC Research Institute, 455 South Main Street, Orange, CA 92868, USA
    Cancer Cell Int 12:41. 2012
  5. ncbi request reprint Zn(2+): a novel ionic mediator of neural injury in brain disease
    J H Weiss
    University of California, Irvine, CA 92697 4292, USA
    Trends Pharmacol Sci 21:395-401. 2000
  6. pmc The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology
    Angele Nalbandian
    Department of Pediatrics, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 7:e46308. 2012

Collaborators

Detail Information

Publications6

  1. pmc Ca permeable AMPA channels in diseases of the nervous system
    John H Weiss
    Department of Neurology, University of California Irvine Irvine, CA, USA
    Front Mol Neurosci 4:42. 2011
    ..This review summarizes some of the clues that have emerged over recent years to the contributions of these channels in disease...
  2. pmc Slow development of ALS-like spinal cord pathology in mutant valosin-containing protein gene knock-in mice
    H Z Yin
    Department of Neurology, University of California, Irvine, CA 92697 4292, USA
    Cell Death Dis 3:e374. 2012
    ....
  3. pmc Mechanisms of rapid reactive oxygen species generation in response to cytosolic ca(2+) or zn(2+) loads in cortical neurons
    Aaron Clausen
    Department of Neurology, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 8:e83347. 2013
    ..This may be of particular relevance to conditions like ischemia in which cytosolic Zn(2+) buffering is impaired due to acidosis and oxidative stress. ..
  4. pmc Cancer stem cells from a rare form of glioblastoma multiforme involving the neurogenic ventricular wall
    Shengwen Calvin Li
    Neuro Oncology Research Laboratory, Center for Neuroscience and Stem Cell Research, Children s Hospital of Orange County CHOC Research Institute, 455 South Main Street, Orange, CA 92868, USA
    Cancer Cell Int 12:41. 2012
    ..abstract:..
  5. ncbi request reprint Zn(2+): a novel ionic mediator of neural injury in brain disease
    J H Weiss
    University of California, Irvine, CA 92697 4292, USA
    Trends Pharmacol Sci 21:395-401. 2000
    ..Further elucidation of the pathological actions of Zn(2+) in the brain should result in new therapeutic approaches to these conditions...
  6. pmc The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology
    Angele Nalbandian
    Department of Pediatrics, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 7:e46308. 2012
    ....

Research Grants21

  1. AMPA/Kainate Receptors, Free Radicals, And Motor Neuron Injury
    John H Weiss; Fiscal Year: 2010
    ..It is hoped that these studies will further clarify sequences of events culminating in selective MN loss in ALS, and thereby facilitate development of new treatment strategies. ..
  2. AMPA/Kainate Receptors, Free Radicals, And Motor Neuron Injury
    John Weiss; Fiscal Year: 2009
    ..It is hoped that these studies will further clarify sequences of events culminating in selective MN loss in ALS, and thereby facilitate development of new treatment strategies. ..
  3. ZN2+ AND CALCIUM PERMEABLE AMPA/KAINATE CHANNELS
    John Weiss; Fiscal Year: 2002
    ..It is hoped that these experiments will provide initial clues to physiological effects of Zn2+ that may be of importance to selective neurodegeneration in disease as well as to normal neuronal functioning. ..
  4. CA2+ AND EXCITOTOXIC DAMAGE OF CULTURED CENTRAL NEURONS
    John Weiss; Fiscal Year: 1993
    ....
  5. CA2+, ZN2+ AND SELECTIVE EXCITOTOXIC NEURODEGENERATION
    John Weiss; Fiscal Year: 2002
    ..Finally studies in slice preparations will examine the role of Ca2+ and Zn2+ flux through Ca-A/K channels in hippocampal pyramidal neuronal injury in situ. ..
  6. AMPA/Kainate Receptors, Free Radicals, And Motor Neuron Injury
    John Weiss; Fiscal Year: 2006
    ..It is hoped that these studies will further clarify sequences of events culminating in selective MN loss in ALS, and thereby facilitate development of new treatment strategies. ..
  7. AMPA/Kainate Receptors, Free Radicals, And Motor Neuron Injury
    John Weiss; Fiscal Year: 2007
    ..It is hoped that these studies will further clarify sequences of events culminating in selective MN loss in ALS, and thereby facilitate development of new treatment strategies. ..
  8. CA2+, ZN2+ AND SELECTIVE EXCITOTOXIC NEURODEGENERATION
    John Weiss; Fiscal Year: 2001
    ..Finally studies in slice preparations will examine the role of Ca2+ and Zn2+ flux through Ca-A/K channels in hippocampal pyramidal neuronal injury in situ. ..
  9. CA++ AND EXCITOTOXIC DAMAGE OF CULTURED CENTRAL NEURONS
    John Weiss; Fiscal Year: 1999
    ....
  10. CA2+ AND EXCITOTOXIC DAMAGE OF CULTURED CENTRAL NEURONS
    John Weiss; Fiscal Year: 1992
    ....
  11. CA2+, ZN2+ AND SELECTIVE EXCITOTOXIC NEURODEGENERATION
    John Weiss; Fiscal Year: 2000
    ..Finally studies in slice preparations will examine the role of Ca2+ and Zn2+ flux through Ca-A/K channels in hippocampal pyramidal neuronal injury in situ. ..
  12. Zn2+, mitochondria and the induction of ischemic neurodegeneration
    John H Weiss; Fiscal Year: 2010
    ..It is hoped that these studies will provide new insights into critical early events in ischemia that will suggest new approaches for new and better treatments to decrease brain damage. ..