John Weiss

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Ca permeable AMPA channels in diseases of the nervous system
    John H Weiss
    Department of Neurology, University of California Irvine Irvine, CA, USA
    Front Mol Neurosci 4:42. 2011
  2. pmc Slow development of ALS-like spinal cord pathology in mutant valosin-containing protein gene knock-in mice
    H Z Yin
    Department of Neurology, University of California, Irvine, CA 92697 4292, USA
    Cell Death Dis 3:e374. 2012
  3. pmc Mechanisms of rapid reactive oxygen species generation in response to cytosolic Ca2+ or Zn2+ loads in cortical neurons
    Aaron Clausen
    Department of Neurology, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 8:e83347. 2013
  4. pmc Cancer stem cells from a rare form of glioblastoma multiforme involving the neurogenic ventricular wall
    Shengwen Calvin Li
    Neuro Oncology Research Laboratory, Center for Neuroscience and Stem Cell Research, Children s Hospital of Orange County CHOC Research Institute, 455 South Main Street, Orange, CA 92868, USA
    Cancer Cell Int 12:41. 2012
  5. ncbi request reprint Zn(2+): a novel ionic mediator of neural injury in brain disease
    J H Weiss
    University of California, Irvine, CA 92697 4292, USA
    Trends Pharmacol Sci 21:395-401. 2000
  6. pmc The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology
    Angele Nalbandian
    Department of Pediatrics, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 7:e46308. 2012

Collaborators

Detail Information

Publications6

  1. pmc Ca permeable AMPA channels in diseases of the nervous system
    John H Weiss
    Department of Neurology, University of California Irvine Irvine, CA, USA
    Front Mol Neurosci 4:42. 2011
    ..This review summarizes some of the clues that have emerged over recent years to the contributions of these channels in disease...
  2. pmc Slow development of ALS-like spinal cord pathology in mutant valosin-containing protein gene knock-in mice
    H Z Yin
    Department of Neurology, University of California, Irvine, CA 92697 4292, USA
    Cell Death Dis 3:e374. 2012
    ....
  3. pmc Mechanisms of rapid reactive oxygen species generation in response to cytosolic Ca2+ or Zn2+ loads in cortical neurons
    Aaron Clausen
    Department of Neurology, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 8:e83347. 2013
    ..This may be of particular relevance to conditions like ischemia in which cytosolic Zn(2+) buffering is impaired due to acidosis and oxidative stress. ..
  4. pmc Cancer stem cells from a rare form of glioblastoma multiforme involving the neurogenic ventricular wall
    Shengwen Calvin Li
    Neuro Oncology Research Laboratory, Center for Neuroscience and Stem Cell Research, Children s Hospital of Orange County CHOC Research Institute, 455 South Main Street, Orange, CA 92868, USA
    Cancer Cell Int 12:41. 2012
    ..abstract:..
  5. ncbi request reprint Zn(2+): a novel ionic mediator of neural injury in brain disease
    J H Weiss
    University of California, Irvine, CA 92697 4292, USA
    Trends Pharmacol Sci 21:395-401. 2000
    ..Further elucidation of the pathological actions of Zn(2+) in the brain should result in new therapeutic approaches to these conditions...
  6. pmc The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology
    Angele Nalbandian
    Department of Pediatrics, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 7:e46308. 2012
    ....

Research Grants3

  1. ZN2+ AND CALCIUM PERMEABLE AMPA/KAINATE CHANNELS
    John Weiss; Fiscal Year: 2002
    ..It is hoped that these experiments will provide initial clues to physiological effects of Zn2+ that may be of importance to selective neurodegeneration in disease as well as to normal neuronal functioning. ..
  2. CA2+, ZN2+ AND SELECTIVE EXCITOTOXIC NEURODEGENERATION
    John Weiss; Fiscal Year: 2002
    ..Finally studies in slice preparations will examine the role of Ca2+ and Zn2+ flux through Ca-A/K channels in hippocampal pyramidal neuronal injury in situ. ..
  3. AMPA/Kainate Receptors, Free Radicals, And Motor Neuron Injury
    John H Weiss; Fiscal Year: 2010
    ..It is hoped that these studies will further clarify sequences of events culminating in selective MN loss in ALS, and thereby facilitate development of new treatment strategies. ..