B Weiss

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Organic and inorganic mercury in neonatal rat brain after prenatal exposure to methylmercury and mercury vapor
    Hiromi Ishitobi
    Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, USA
    Environ Health Perspect 118:242-8. 2010
  2. pmc Lead, manganese, and methylmercury as risk factors for neurobehavioral impairment in advanced age
    Bernard Weiss
    Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA
    Int J Alzheimers Dis 2011:607543. 2010
  3. pmc Anogenital distance: defining "normal"
    Bernard Weiss
    Environ Health Perspect 114:A399; author reply A399. 2006
  4. pmc The intersection of neurotoxicology and endocrine disruption
    Bernard Weiss
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 33:1410-9. 2012
  5. pmc Synthetic food colors and neurobehavioral hazards: the view from environmental health research
    Bernard Weiss
    Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Ave, Rochester, NY 14642 USA
    Environ Health Perspect 120:1-5. 2012
  6. pmc The new tapestry of risk assessment
    Bernard Weiss
    Department of Environmental Medicine and Environmental Health Sciences Center, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 29:883-90. 2008
  7. pmc Chemobrain: a translational challenge for neurotoxicology
    Bernard Weiss
    Department of Environmental Medicine, Environmental Health Sciences Center, and Center for Reproductive Epidemiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Neurotoxicology 29:891-8. 2008
  8. pmc Can endocrine disruptors influence neuroplasticity in the aging brain?
    Bernard Weiss
    Department of Environmental Medicine, Environmental Health Sciences Center, and Center for Reproductive Epidemiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States
    Neurotoxicology 28:938-50. 2007
  9. ncbi request reprint Perinatal and lifetime exposure to methylmercury in the mouse: behavioral effects
    Bernard Weiss
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 26:675-90. 2005
  10. ncbi request reprint Economic implications of manganese neurotoxicity
    Bernard Weiss
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 27:362-8. 2006

Research Grants

Collaborators

Detail Information

Publications45

  1. pmc Organic and inorganic mercury in neonatal rat brain after prenatal exposure to methylmercury and mercury vapor
    Hiromi Ishitobi
    Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, USA
    Environ Health Perspect 118:242-8. 2010
    ..Most of our knowledge of the neurotoxicity of Hg is based on research devoted to studying only one form at a time, mostly MeHg...
  2. pmc Lead, manganese, and methylmercury as risk factors for neurobehavioral impairment in advanced age
    Bernard Weiss
    Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA
    Int J Alzheimers Dis 2011:607543. 2010
    ..Among the critical unresolved questions is timing; that is, during which periods of the lifespan, including early development, do environmental exposures lay the foundations for their ultimate effects?..
  3. pmc Anogenital distance: defining "normal"
    Bernard Weiss
    Environ Health Perspect 114:A399; author reply A399. 2006
  4. pmc The intersection of neurotoxicology and endocrine disruption
    Bernard Weiss
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 33:1410-9. 2012
    ..All these facets of endocrine disruption are pieces of a puzzle that challenge neurotoxicologists for solutions...
  5. pmc Synthetic food colors and neurobehavioral hazards: the view from environmental health research
    Bernard Weiss
    Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Ave, Rochester, NY 14642 USA
    Environ Health Perspect 120:1-5. 2012
    ..In preparation for the hearing, the FDA reviewed the available evidence and concluded that it did not warrant further agency action...
  6. pmc The new tapestry of risk assessment
    Bernard Weiss
    Department of Environmental Medicine and Environmental Health Sciences Center, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 29:883-90. 2008
    ..Although neurotoxicologists have come to recognize the complexities of assessing risk in all its dimensions, they still face the challenge of communicating this view to the health professions at large...
  7. pmc Chemobrain: a translational challenge for neurotoxicology
    Bernard Weiss
    Department of Environmental Medicine, Environmental Health Sciences Center, and Center for Reproductive Epidemiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Neurotoxicology 29:891-8. 2008
    ..This commentary describes some of the potential methods and encourages neurotoxicologists to enlist their unique skills in the service of these needs...
  8. pmc Can endocrine disruptors influence neuroplasticity in the aging brain?
    Bernard Weiss
    Department of Environmental Medicine, Environmental Health Sciences Center, and Center for Reproductive Epidemiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States
    Neurotoxicology 28:938-50. 2007
    ....
  9. ncbi request reprint Perinatal and lifetime exposure to methylmercury in the mouse: behavioral effects
    Bernard Weiss
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 26:675-90. 2005
    ..Lifetime evaluations of exposure to toxicants, beginning with early development, should be a component of the risk assessment process for neurotoxicity...
  10. ncbi request reprint Economic implications of manganese neurotoxicity
    Bernard Weiss
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 27:362-8. 2006
    ..A relatively small increment in risk, expressed as a leftward shift in the age prevalence of PD, incurs significant economic costs...
  11. ncbi request reprint Pesticides
    Bernard Weiss
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Pediatrics 113:1030-6. 2004
    ..It is essential to study whether there are subtle neurologic effects that may result from low-level pesticide exposures in individual patients...
  12. pmc Social ecology of children's vulnerability to environmental pollutants
    Bernard Weiss
    Department of Environmental Medicine, Environmental Health Sciences Center, and Center for Reproductive Epidemiology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Environ Health Perspect 114:1479-85. 2006
    ..Such approaches blur the reality of how the early environment establishes enduring biologic substrates...
  13. pmc Ethics assessment as an adjunct to risk assessment in the evaluation of developmental neurotoxicants
    B Weiss
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA 14642, USA
    Environ Health Perspect 109:905-8. 2001
    ..A scheme for doing so can be derived from the procedures of fuzzy logic, which allow rules to be formulated that are applicable to ethical principles. Such an approach incorporates some of the tenets of the precautionary principle...
  14. pmc The first 83 and the next 83: perspectives on neurotoxicology
    Bernard Weiss
    Department of Environmental Medicine, Environmental Health Sciences Center, and Center for Reproductive Epidemiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 30:832-50. 2009
    ..The commentary also describes the author's views of some of the new directions open to neurotoxicology, such as the pursuit of questions about endocrine disruptors, countermeasures for brain aging, and epigenetics...
  15. ncbi request reprint A Web-based survey method for evaluating different components of uncertainty in relative health risk judgments
    B Weiss
    Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, NY 14642, USA
    Neurotoxicology 22:707-21. 2001
    ..Comparative risk endeavors conducted in this format make their aims and content easy to modify. Data obtained by such a method can serve as pointers to new research initiatives, to regulator priorities, or to further iterations...
  16. pmc Evaluation of multiple neurotoxic outcomes in cancer chemotherapy
    Bernard Weiss
    University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Adv Exp Med Biol 678:96-112. 2010
    ..Schedule-controlled operant behavior offers the most promising source of animal models...
  17. pmc Endocrine disruptors as a threat to neurological function
    Bernard Weiss
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Neurol Sci 305:11-21. 2011
    ..The limited research conducted so far on endocrine disruptors, aging, and neurogenesis argues that they should be overlooked no longer...
  18. pmc Vulnerability of children and the developing brain to neurotoxic hazards
    B Weiss
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Environ Health Perspect 108:375-81. 2000
    ..It is especially important to consider ways of dealing with multiple risks and their combinations in addition to the prevailing practice of estimating risks in isolation...
  19. pmc Same sex, no sex, and unaware sex in neurotoxicology
    Bernard Weiss
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, United States
    Neurotoxicology 32:509-17. 2011
    ..Often, the differences evoking the most discussion are subtle in scope. They do not lend themselves to the typical analyses conducted by experimenters; that is, reliance on mean differences and null hypothesis testing...
  20. pmc Methylmercury contamination of laboratory animal diets
    Bernard Weiss
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Environ Health Perspect 113:1120-2. 2005
    ....
  21. ncbi request reprint A risk assessment perspective on the neurobehavioral toxicity of endocrine disruptors
    B Weiss
    Department of Environmental Medicine, University of Rochester Medical Center, NY 14642, USA
    Toxicol Ind Health 14:341-59. 1998
    ..These multiple facets of neurobehavioral toxicity, and, by extension, their coupling to endocrine disruptors, imply a risk assessment process that corresponds, in many ways, to the global views adopted by ecotoxicologists...
  22. ncbi request reprint Prenatal cocaine exposure produces gender-specific motor effects in aged rats
    V P Markowski
    Department of Environmental Medicine, University of Rochester School of Medicine, NY 14642, USA
    Neurotoxicol Teratol 20:43-53. 1998
    ....
  23. pmc The intersection of risk assessment and neurobehavioral toxicity
    B Weiss
    Department of Environmental Medicine, University of Rochester Medical Center, NY 14642, USA
    Environ Health Perspect 104:173-7. 1996
    ..They extend beyond what would be offered in a primer of methodology. Instead, these appraisals are framed as issues into which what are usually construed as methodologies have been embedded...
  24. ncbi request reprint Perinatal and lifetime exposure to methylmercury in the mouse: blood and brain concentrations of mercury to 26 months of age
    S Stern
    Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, NY 14642, USA
    Neurotoxicology 22:467-77. 2001
    ..In the 3 ppm lifetime group, both brain and blood levels rose significantly between months 14 and 26, suggesting an interaction between dose and age...
  25. ncbi request reprint Evaluation of techniques for assessing neurobehavioral development in children
    P W Davidson
    Department of Pediatrics, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Neurotoxicology 21:957-72. 2000
    ..Our findings suggest a number of tests and procedures with the potential for inclusion in test batteries aimed at the exploration of adverse neurodevelopmental effects...
  26. ncbi request reprint Manganese in the context of an integrated risk and decision process
    B Weiss
    University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Neurotoxicology 20:519-25. 1999
    ....
  27. pmc Prenatal phthalate exposure and reduced masculine play in boys
    S H Swan
    Department of Obstetrics and Gynecology, University of Rochester, Rochester, NY, USA
    Int J Androl 33:259-69. 2010
    ..Our findings suggest that these ubiquitous environmental chemicals have the potential to alter androgen-responsive brain development in humans...
  28. pmc Methods to identify and characterize developmental neurotoxicity for human health risk assessment. I: behavioral effects
    D A Cory-Slechta
    Department of Environmental Medicine, University of Rochester Medical School, Rochester, New York, USA
    Environ Health Perspect 109:79-91. 2001
    ....
  29. ncbi request reprint Development and validation of a test battery to assess subtle neurodevelopmental differences in children
    Philip W Davidson
    University of Rochester School of Medicine, Rochester, NY, USA
    Neurotoxicology 27:951-69. 2006
    ..Further studies are needed to confirm the capability of the RTB to detect subtle changes associated with neurotoxic exposures...
  30. ncbi request reprint Prenatal methyl mercury exposure from fish consumption and child development: a review of evidence and perspectives from the Seychelles Child Development Study
    Philip W Davidson
    University of Rochester School of Medicine and Dentistry, USA
    Neurotoxicology 27:1106-9. 2006
    ..This suggests that the association between prenatal exposure and child development may be more complex than originally believed. This paper reviews the SCDS main cohort study results and presents our current interpretations...
  31. ncbi request reprint Thimerosal distribution and metabolism in neonatal mice: comparison with methyl mercury
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Appl Toxicol 27:511-8. 2007
    ..The data showing significant kinetic differences in tissue distribution and metabolism of mercury species challenge the assumption that ethyl mercury is toxicologically identical to methyl mercury...
  32. pmc Sexually dimorphic nonreproductive behaviors as indicators of endocrine disruption
    Bernard Weiss
    Department of Environmental Medicine, Medical Center, University of Rochester School of Medicine and Dentistry, 575 Elmwood Avenue, Rochester, NY 14642, USA
    Environ Health Perspect 110:387-91. 2002
    ..Given the societal importance of risk assessments applied to potential developmental neurotoxicants, studies should be deemed questionable if they fail to include outcome measures based on sexual dimorphisms in nonreproductive behaviors...
  33. pmc Sexually dimorphic behavioral responses to prenatal dioxin exposure
    Rieko Hojo
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Environ Health Perspect 110:247-54. 2002
    ..02 ng/kg. The corresponding ED(01) was 0.30 ng/kg with a 95% lower bound of 0.20 ng/kg. These values fall close to, but below, current estimates of human body burdens of 13 ng/kg, based on TCDD toxic equivalents...
  34. ncbi request reprint Mercury exposure and child development outcomes
    Philip W Davidson
    Strong Center for Developmental Disabilities, Golisano Children s Hospital at Strong, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Pediatrics 113:1023-9. 2004
    ..Our intent is to focus the debate about mercury on 1) additional research that should be sought and 2) defining the principal issues that public policy makers face...
  35. ncbi request reprint Vulnerability to pesticide neurotoxicity is a lifetime issue
    B Weiss
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, NY 14642, USA
    Neurotoxicology 21:67-73. 2000
    ....
  36. pmc Experimental strategies for research on multiple chemical sensitivity
    B Weiss
    University of Rochester School of Medicine and Dentistry, New York 14642, USA
    Environ Health Perspect 105:487-94. 1997
    ..Explicit time series analyses take account of this aspect and can correct for it to determine the impact of an intervention such as a chemical exposure...
  37. pmc Prenatal methyl mercury exposure in relation to neurodevelopment and behavior at 19 years of age in the Seychelles Child Development Study
    E van Wijngaarden
    University of Rochester School of Medicine and Dentistry, Rochester, NY, United States Electronic address
    Neurotoxicol Teratol 39:19-25. 2013
    ..To determine if these associations persist into young adulthood, we examined the relationship between prenatal MeHg exposure, recent PUFA exposure and subjects' neurodevelopment and behavior at 19 years of age...
  38. pmc Silent latency periods in methylmercury poisoning and in neurodegenerative disease
    Bernard Weiss
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Environ Health Perspect 110:851-4. 2002
    ..Parallels are drawn with other diseases that affect the central nervous system, such as Parkinson disease and post-polio syndrome, that also reflect the delayed appearance of central nervous system damage...
  39. ncbi request reprint Sex-specific alterations of cerebral cortical cell size in rats exposed prenatally to dioxin
    Rieko Hojo
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Appl Toxicol 26:25-34. 2006
    ..These findings demonstrate that prenatal exposure to TCDD alters the normal patterns of cortical cell asymmetry in a manner consistent with our previous data on thickness patterns...
  40. ncbi request reprint Sexually dimorphic alterations of brain cortical dominance in rats prenatally exposed to TCDD
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Appl Toxicol 22:129-37. 2002
    ..These data demonstrate that prenatal exposure to TCDD reduces cortical thickness and alters the normal pattern of cortical asymmetry, a finding consistent with the sexually dimorphic behavioral effects induced by this agent...
  41. ncbi request reprint Impaired cued delayed alternation behavior in adult rat offspring following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on gestation day 15
    Vincent P Markowski
    Department of Psychology, University of Southern Maine, Portland, ME 04104 9300, USA
    Neurotoxicol Teratol 24:209-18. 2002
    ....
  42. ncbi request reprint Environmental toxicants and developmental disabilities: a challenge for psychologists
    Susan M Koger
    Department of Psychology, Willamette University, Salem, OR 97301, USA
    Am Psychol 60:243-55. 2005
    ....
  43. pmc A rationale for lowering the blood lead action level from 10 to 2 microg/dL
    Steven G Gilbert
    Institute of Neurotoxicology and Neurological Disorders, 8232 14th Avenue NE, Seattle, WA 98115, USA
    Neurotoxicology 27:693-701. 2006
    ..By lowering the blood action level, CDC will promote policies and initiatives designed to further reduce children's exposure to this potent developmental neurotoxicant...
  44. ncbi request reprint The potential adverse health effects of dental amalgam
    Amy M Brownawell
    Life Sciences Research Office, Bethesda, Maryland 20814 3998, USA
    Toxicol Rev 24:1-10. 2005
    ..This review has uncovered no convincing evidence pointing to any adverse health effects that are attributable to dental amalgam restorations besides hypersensitivity in some individuals...

Research Grants5

  1. Neurotoxic Interactions of Different Forms of Mercury
    Bernard Weiss; Fiscal Year: 2005
    ..The acquisition of these data offers a firm foundation for determining the risks to neurobehavioral development of concurrent exposures to both mercury species. ..
  2. Neurotoxic Interactions of Different Forms of Mercury
    Bernard Weiss; Fiscal Year: 2006
    ..The acquisition of these data offers a firm foundation for determining the risks to neurobehavioral development of concurrent exposures to both mercury species. ..
  3. Developmental Neurotoxicity of Phthalate Esters
    Bernard Weiss; Fiscal Year: 2007
    ..Because phthalates act as anti-androgens, they have the potential to interfere with human brain and behavioral development. The proposed research will examine this question in rats, and translate its implications into human relevance. ..
  4. Neurotoxic Interactions of Different Forms of Mercury
    Bernard Weiss; Fiscal Year: 2007
    ..The acquisition of these data offers a firm foundation for determining the risks to neurobehavioral development of concurrent exposures to both mercury species. ..