Research Topics
| Richard A WeisigerSummaryAffiliation: University of California Country: USA Publications
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Publications
Saturable stimulation of fatty acid transport through model cytoplasm by soluble binding proteinR A Weisiger
Department of Medicine and the Liver Center, University of California, San Francisco, California 94143 0538, USA
Am J Physiol 277:G109-19. 1999..However, slow interchange of fatty acid between the binding protein and membranes also appears to influence the transport rate in this model system...
Affinity of human serum albumin for bilirubin varies with albumin concentration and buffer composition: results of a novel ultrafiltration methodR A Weisiger
Department of Medicine and the Liver Center, University of California, San Francisco, California 94143 0538, USA
J Biol Chem 276:29953-60. 2001..Thus, the affinity of human albumin for bilirubin is not constant, but varies with both albumin concentration and buffer composition. Binding may be considerably less avid at physiological albumin concentrations than previously believed...
Transfer of fatty acids between intracellular membranes: roles of soluble binding proteins, distance, and timeR A Weisiger
Department of Medicine and the Liver Center, University of California, San Francisco, California 94143 0538, USA
Am J Physiol Gastrointest Liver Physiol 282:G105-15. 2002..Individual FABPs may have evolved to match the membrane separations and densities found in specific cell lines...
Cytosolic fatty acid binding proteins catalyze two distinct steps in intracellular transport of their ligandsRichard A Weisiger
Department of Medicine and the Liver Center, University of California, San Francisco, CA 94143 0538, USA
Mol Cell Biochem 239:35-43. 2002..Different FABPs may have evolved to match the specific transport requirements of the cell type within which they are found...
Mechanisms of intracellular fatty acid transport: role of cytoplasmic-binding proteinsRichard A Weisiger
Department of Medicine, University of California, 357 Sciences Building, San Francisco, CA 94143 0538, USA
J Mol Neurosci 33:42-4. 2007..Thus, FABPs serve complementary intracellular transport functions. These conclusions may apply to other cytosolic proteins that bind poorly-soluble molecules...
