Research Topics
Species | Gregory S WeinsteinSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Publications
Transoral robotic surgery alone for oropharyngeal cancer: an analysis of local controlGregory S Weinstein
Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Medical Center, Philadelphia, USA
Arch Otolaryngol Head Neck Surg 138:628-34. 2012..To evaluate local control following transoral robotic surgery (TORS) with the da Vinci Surgical System (Intuitive Surgical Inc) as a single treatment modality for oropharyngeal squamous cell carcinoma (OSCC)...- Selective neck dissection and deintensified postoperative radiation and chemotherapy for oropharyngeal cancer: a subset analysis of the University of Pennsylvania transoral robotic surgery trialGregory S Weinstein
Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
Laryngoscope 120:1749-55. 2010.... - Transoral robotic surgery: does the ends justify the means?Gregory S Weinstein
Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Curr Opin Otolaryngol Head Neck Surg 17:126-31. 2009..Transoral robotic surgery is in its infancy, but, indeed, there have been some questions raised about the role of these innovative robotic surgical techniques... 
Transoral robotic surgery: supraglottic laryngectomy in a canine modelGregory S Weinstein
Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Laryngoscope 115:1315-9. 2005..To develop a technique for computer enhanced robotic transoral supraglottic partial laryngectomy in the canine model...- Transoral robotic surgery for advanced oropharyngeal carcinomaGregory S Weinstein
Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
Arch Otolaryngol Head Neck Surg 136:1079-85. 2010..To determine the oncologic and functional outcomes in patients undergoing primary transoral robotic surgery followed by adjuvant therapy as indicated with a minimum of 18-month follow-up for advanced oropharyngeal carcinoma... - Transoral robotic surgery: radical tonsillectomyGregory S Weinstein
Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
Arch Otolaryngol Head Neck Surg 133:1220-6. 2007..To describe and show the feasibility of a new surgical technique for transoral robotic surgery (TORS) radical tonsillectomy... - Transoral robotic surgery: a multicenter study to assess feasibility, safety, and surgical marginsGregory S Weinstein
Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Laryngoscope 122:1701-7. 2012.... - Pilot study of postoperative reirradiation, chemotherapy, and amifostine after surgical salvage for recurrent head-and-neck cancerMitchell Machtay
Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia, PA, USA
Int J Radiat Oncol Biol Phys 59:72-7. 2004..We designed a prospective protocol to determine the feasibility, toxicity, and preliminary efficacy of a regimen of postoperative reirradiation, chemotherapy and the radioprotector amifostine after salvage head-and-neck surgery... - Organ preservation therapy using induction plus concurrent chemoradiation for advanced resectable oropharyngeal carcinoma: a University of Pennsylvania Phase II TrialMitchell Machtay
Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia 19104, USA
J Clin Oncol 20:3964-71. 2002..To determine the efficacy, feasibility, and toxicity of a new regimen for locally advanced oropharyngeal carcinoma... - Characterization CSMD1 in a large set of primary lung, head and neck, breast and skin cancer tissuesChangqing Ma
Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
Cancer Biol Ther 8:907-16. 2009..We also show that deletions of CSMD1 and aberrant splicing contribute to altered CSMD1 function in vivo... - Transoral robotic surgery of the skull base: a cadaver and feasibility studyJohn Y K Lee
Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA
ORL J Otorhinolaryngol Relat Spec 72:181-7. 2010..The goal of this study was to determine the potential role as well as the current limitations of the da Vinci Surgical System robot in transoral surgery of the skull base... - Robotic skull base surgery: preclinical investigations to human clinical applicationBERT W O'MALLEY
Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
Arch Otolaryngol Head Neck Surg 133:1215-9. 2007..To develop a minimally invasive surgical technique for the treatment of parapharyngeal space and infratemporal fossa skull base neoplasms using the technical and optical advantages of robotic surgical instrumentation... - Transoral robotic surgery (TORS): glottic microsurgery in a canine modelBERT W O'MALLEY
Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Voice 20:263-8. 2006..We hypothesize that bimanual, three-dimensional robotic surgery will prove valuable for glottic microsurgical procedures... - Transoral robotic surgery for parapharyngeal space tumorsBERT W O'MALLEY
Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
ORL J Otorhinolaryngol Relat Spec 72:332-6. 2010..To evaluate the outcomes of patients with parapharyngeal space (PPS) tumors treated with a transoral robotic surgery (TORS) approach... - Transoral robotic surgery: supraglottic partial laryngectomyGregory S Weinstein
Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Ann Otol Rhinol Laryngol 116:19-23. 2007..We assessed the feasibility of performing transoral supraglottic partial laryngectomy with robotic instrumentation... - Preliminary investigation of symptom distress in the head and neck patient population: validation of a measurement instrumentHeather A Jones
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Am J Clin Oncol 29:158-62. 2006..CONCLUSION: The HNDS is a valid measure of acute symptom distress and appears able to discriminate between the chemoradiation and radiation alone patients. There is considerable variation in symptoms that cause these patients distress... 
Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcomeSydney M Evans
Department of Radiation Oncology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6072, USA
Int J Radiat Oncol Biol Phys 69:1024-31. 2007..EF5, a 2-nitroimidazole hypoxia marker, was used to study the presence, levels, and prognostic significance of hypoxia in primary head and neck squamous cell tumors...- Transoral robotic surgery and human papillomavirus status: Oncologic resultsMarc A Cohen
Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
Head Neck 33:573-80. 2011..The purpose of this study was to assess HPV-related outcomes after transoral robotic surgery (TORS) with adjuvant therapy as indicated... - Parotidectomy in the treatment of aggressive cutaneous malignanciesStephen Y Lai
Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania Medical Center, 5 Silverstein/Ravdin, 3400 Spruce St, Philadelphia, PA 19104, USA
Arch Otolaryngol Head Neck Surg 128:521-6. 2002..A systematic approach to the management of the parotid and facial nerve in the presence of these aggressive tumors is required. Despite comprehensive treatment, local recurrence of ANMSC and mortality remain high... - A phase I study of SPI-077 (Stealth liposomal cisplatin) concurrent with radiation therapy for locally advanced head and neck cancerDavid I Rosenthal
Department of Radiation Oncology, Head and Neck Surgery, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
Invest New Drugs 20:343-9. 2002..We performed a Phase I study of Stealth liposomal cisplatin (SPI-077) concurrent with RT for head and neck squamous cell carcinoma (HNSCC)... - Relative risk of stroke in head and neck carcinoma patients treated with external cervical irradiationJeffrey C Haynes
Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
Laryngoscope 112:1883-7. 2002..Although the relative risk is approximately doubled, the absolute risk is modest in comparison to the risk of cancer recurrence. Further study of this association and possible interventions is warranted... - Transoral robotic surgery (TORS) for base of tongue neoplasmsBERT W O'MALLEY
Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
Laryngoscope 116:1465-72. 2006..To develop a minimally invasive surgical technique for the treatment of base of tongue neoplasms using the optical and technical advantages of robotic surgical instrumentation... - Transoral robotic surgery and adjuvant therapy for oropharyngeal carcinomas and the influence of p16(INK4a) on treatment outcomesHarry Quon
Department of Radiation Oncology, Philadelphia, Pennsylvania, U S A Department of Otorhinolaryngology Head and Neck Surgery, Philadelphia, Pennsylvania, U S A Abramson Cancer Center, Philadelphia, Pennsylvania, U S A University of Pennsylvania, Philadelphia, Pennsylvania, U S A
Laryngoscope 123:635-40. 2013..To determine the prognostic influence of p16(INK4a) immunohistochemistry on the survival of resectable oropharyngeal carcinomas (OPSCC)... - Accuracy of magnetic resonance imaging in predicting absence of fixation of head and neck cancer to the prevertebral spaceWendy C Hsu
Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, USA
Head Neck 27:95-100. 2005..CONCLUSION: In patients with advanced head and neck carcinomas, preservation of the fat between the tumor and the prevertebral musculature on unenhanced T1-weighted images reliably predicts absence of prevertebral space fixation... - Postoperative adjuvant therapy after transoral robotic resection for oropharyngeal carcinomas: rationale and current treatment approachHarry Quon
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA
ORL J Otorhinolaryngol Relat Spec 73:121-30. 2011.... - Design and impact of intraoperative pathways for head and neck resection and reconstructionAra A Chalian
Department of Otorhinolaryngology Head and Neck Surgery, Hospital of the University of Pennsylvania, Philadelphia 19104 4283, USA
Arch Otolaryngol Head Neck Surg 128:892-6. 2002.... - Transoral robot-assisted lingual tonsillectomy and uvulopalatopharyngoplasty for obstructive sleep apneaJonathan M Lee
Department of Otorhinolaryngology Head and Neck Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Ann Otol Rhinol Laryngol 121:635-9. 2012..We assessed the use of transoral robot-assisted lingual tonsillectomy and uvulopalatopharyngoplasty for the surgical management of tongue base obstruction in patients with obstructive sleep apnea... - Maintenance of hemostasis in transoral robotic surgeryNeil G Hockstein
Department of Otorhinolaryngology Head and Neck Surgery, The University of Pennsylvania, Philadelphia, PA, USA
ORL J Otorhinolaryngol Relat Spec 67:220-4. 2005..One potential limitation is the management of bleeding in transoral pharyngeal and laryngeal surgery, which is critical to prevent both intravascular volume loss and aspiration... - Transoral robotic surgery of craniocervical junction and atlantoaxial spine: a cadaveric studyJohn Y K Lee
Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Neurosurg Spine 12:13-8. 2010..The goal of this study was to determine the potential role and current limitations of the da Vinci surgical robot in transoral decompression of craniocervical junction (CCJ)... - Impact of age on clinical care pathway length of stay after complex head and neck resectionSarah H Kagan
University of Pennsylvania School of Nursing, 420 Guardian Drive, Philadelphia, Pennsylvania 19104 6096, USA
Head Neck 24:545-8; discussion 545. 2002..Aggregate clinical results for 43 patients, enrolled in the CCP from June 1996-July 1997, are described. Patient age, comorbid status, and postoperative complications are analyzed with respect to impact on LOS... - Reconstruction of complex total parotidectomy defects using the free anterolateral thigh flap: a classification system and algorithmRiver M Elliott
Division of Plastic Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA
Ann Plast Surg 66:429-37. 2011.... - Anesthetic considerations for transoral robotic surgeryJohn J Chi
Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
Anesthesiol Clin 28:411-22. 2010..This article focuses on TORS and the goal of which is to provide the anesthesiologist with a foundation for caring for the TORS patient in the perioperative period... - A pilot study of respiratory inductance plethysmography as a safe, noninvasive detector of jet ventilation under general anesthesiaJoshua H Atkins
Department of Anesthesiology and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Anesth Analg 111:1168-75. 2010..We performed an observational pilot study of respiratory inductance plethysmography as a detector of jet ventilation... - Low-grade mucoepidermoid carcinoma of the subglottis treated with organ-preservation surgeryDaniel L Monin
Department of Otorhinolaryngology-Head and Neck Surgery Hospital of the University of Pennsylvania, Philadelphia, USA
Ear Nose Throat J 85:332-6. 2006..At follow-up 15 months postoperatively, the patient remained disease-free, and laryngeal function was intact... - Assessment of intraoperative safety in transoral robotic surgeryNeil G Hockstein
Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Laryngoscope 116:165-8. 2006..We hypothesize that these particular risks of transoral surgery are similar with robotic assistance compared with conventional transoral surgery... - Clinical care pathway for head and neck cancer: a valuable tool for decreasing resource utilizationKristin M Gendron
Department of Otorhinolaryngology Head and Neck Surgery, 3400 Spruce St, 5 Ravdin, Philadelphia, PA 19104, USA
Arch Otolaryngol Head Neck Surg 128:258-62. 2002..To evaluate the durability over time of the reduction of resource utilization after implementing a clinical care pathway (CCP) for head and neck cancer surgery... - Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomasDevraj Basu
Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA
Cell Cycle 10:2008-16. 2011..Further, they provide evidence of mesenchymal-like subsets being well-represented across advanced stage SCCs, suggesting that intrinsic drug resistance in this subpopulation has high clinical relevance... - Importance of the treatment package time in surgery and postoperative radiation therapy for squamous carcinoma of the head and neckDavid I Rosenthal
Department of Radiation Oncology, Hospital of the University of Pennsylvania, 3400 Spruce Street, 2 Donner, Philadelphia, PA 19104, USA
Head Neck 24:115-26. 2002..CONCLUSIONS: A total treatment package time of <100 days is associated with improved tumor control and survival. Every effort should be made to keep the time from surgery to the completion of postoperative RT to <100 days... - Robotic anterior and midline skull base surgery: preclinical investigationsBERT W O'MALLEY
Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 69:S125-8. 2007..To develop a minimally invasive surgical technique to access the midline and anterior skull base using the optical and technical advantages of robotic surgical instrumentation... - Identification of a gene signature for rapid screening of oral squamous cell carcinomaAmy F Ziober
Department of Otorhinolaryngology-Head and Neck Surgery, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
Clin Cancer Res 12:5960-71. 2006.... - Genome-wide profiling of oral squamous cell carcinoma by array-based comparative genomic hybridizationAnthony Sparano
Department of Otorhinolaryngology, Head and Neck, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Laryngoscope 116:735-41. 2006..CONCLUSIONS: Genome-wide aCGH can be used to detect and map CNAs in OSCC tissue specimens with high resolution. These data implicate several candidate genes and gene pathways in the tumorigenesis of sporadic OSCC... - Voice rehabilitation after external partial laryngeal surgeryAnthony Sparano
Department of Otorhinolaryngology: Head and Neck Surgery, The University of Pennsylvania Medical Center, 3400 Spruce Street, Ravdin 5, Philadelphia, PA 19104, USA
Otolaryngol Clin North Am 37:637-53. 2004..Because the spectrum of these changes maybe broad, the role of professional rehabilitation therapy has taken an involved, multidisciplinary approach, with an integrated understanding of anticipated and potential functional outcomes... - Steatocystoma simplex of the infratemporal fossa: an uncommon location for a rare entityYekaterina A Koshkareva
Department of Otolaryngology Head and Neck Surgery, Temple University School of Medicine, Kresge Bldg, 1st Floor, 3400 N Broad St, Philadelphia, PA 19140, USA
Ear Nose Throat J 90:E16-8. 2011..We also describe the radiologic and pathologic features of this entity, which might aid in diagnosis and management, and we discuss its etiology and treatment options... - Larynx preservation with supracricoid partial laryngectomy with cricohyoidoepiglottopexy. Correlation of videostroboscopic findings and voice parametersGregory S Weinstein
Department of Otorhinolaryngology-Head and Neck Surgery, The University of Pennsylvania Medical Center, Philadelphia 19104, USA
Ann Otol Rhinol Laryngol 111:1-7. 2002..Patients with lower periodicity and symmetry scores tended to have lower jitter and shimmer percentages... - Nonsurgical treatment of laryngeal cancerGregory S Weinstein
N Engl J Med 350:1049-53; author reply 1049-53. 2004 - Supracricoid partial laryngectomy: an organ-preservation surgery for laryngeal malignancyF Christopher Holsinger
Department of Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Box 441, Houston, TX, USA
Curr Probl Cancer 29:190-200. 2005 - Technical refinements in the supracricoid partial laryngectomy to optimize functional outcomesF Christopher Holsinger
Department of Head and Neck Surgery, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030-4009, USA
J Am Coll Surg 201:809-20. 2005 - Tympanomastoid suture and digastric muscle in cadaver and live parotidectomyRobert L Witt
Christiana Care Health Systems, Wilmington, Delaware 19806, USA
Laryngoscope 115:574-7. 2005..To prove that the tympanomastoid suture (TMS) is a significantly closer and less variable anatomic landmark to the facial nerve than the posterior-superior margin of the posterior belly of the digastric muscle (PBD) in parotid surgery... - American Society of Clinical Oncology clinical practice guideline for the use of larynx-preservation strategies in the treatment of laryngeal cancerDavid G Pfister
American Society of Clinical Oncology, Alexandria, VA, VA 22314, USA
J Clin Oncol 24:3693-704. 2006....