Myron Weiner

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. pmc Videoconference diagnosis and management of Choctaw Indian dementia patients
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, USA
    Alzheimers Dement 7:562-6. 2011
  2. ncbi request reprint Prevalence and incidence of major depressive disorder in Alzheimer's disease: findings from two databases
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Dement Geriatr Cogn Disord 13:8-12. 2002
  3. ncbi request reprint Comparison of the test of everyday functional abilities with a direct measure of daily function
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9129, USA
    Dement Geriatr Cogn Disord 22:83-6. 2006
  4. ncbi request reprint Comparison of Alzheimer's disease in Native Americans and Whites
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9070, USA
    Int Psychogeriatr 15:367-75. 2003
  5. pmc Language in Alzheimer's disease
    Myron F Weiner
    University of Texas Southwestern Medical Center, Dallas, TX 75390 9129, USA
    J Clin Psychiatry 69:1223-7. 2008
  6. pmc Plasma 24S-hydroxycholesterol and other oxysterols in acute closed head injury
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Brain Inj 22:611-5. 2008
  7. pmc Atherosclerosis risk factors in American Indians with Alzheimer disease: preliminary findings
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Alzheimer Dis Assoc Disord 22:245-8. 2008
  8. pmc Annualized functional change in Alzheimer's disease participants and normal controls
    Myron Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9129, USA
    Clin Neuropsychol 22:801-6. 2008
  9. pmc Perspective on race and ethnicity in Alzheimer's disease research
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Alzheimers Dement 4:233-8. 2008
  10. pmc Brain MRI, apoliprotein E genotype, and plasma homocysteine in American Indian Alzheimer disease patients and Indian controls
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9129, USA
    Curr Alzheimer Res 6:52-8. 2009

Detail Information

Publications55

  1. pmc Videoconference diagnosis and management of Choctaw Indian dementia patients
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, USA
    Alzheimers Dement 7:562-6. 2011
    ..This study reports a 5-year experience using videoconference (VC) technology in diagnosing and treating adult members of the Choctaw Nation with symptoms or complaints of cognitive impairment...
  2. ncbi request reprint Prevalence and incidence of major depressive disorder in Alzheimer's disease: findings from two databases
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Dement Geriatr Cogn Disord 13:8-12. 2002
    ..Reports on the frequency of major depression in Alzheimer's disease are conflicting, some suggesting that it is frequent, others suggesting that it is uncommon...
  3. ncbi request reprint Comparison of the test of everyday functional abilities with a direct measure of daily function
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9129, USA
    Dement Geriatr Cogn Disord 22:83-6. 2006
    ..To compare scores for dementia patients on a newly developed direct test of instrumental activities of daily living (IADLs) to scores on a widely accepted functional measure...
  4. ncbi request reprint Comparison of Alzheimer's disease in Native Americans and Whites
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9070, USA
    Int Psychogeriatr 15:367-75. 2003
    ....
  5. pmc Language in Alzheimer's disease
    Myron F Weiner
    University of Texas Southwestern Medical Center, Dallas, TX 75390 9129, USA
    J Clin Psychiatry 69:1223-7. 2008
    ..To ascertain the clinical utility of language examination by psychiatrists in evaluating Alzheimer's disease (AD) patients...
  6. pmc Plasma 24S-hydroxycholesterol and other oxysterols in acute closed head injury
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Brain Inj 22:611-5. 2008
    ..To determine if plasma levels of 24S-hydroxycholesterol, the primary catabolite of brain cholesterol, provide a measure of axonal damage in acute brain trauma...
  7. pmc Atherosclerosis risk factors in American Indians with Alzheimer disease: preliminary findings
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Alzheimer Dis Assoc Disord 22:245-8. 2008
    ..This suggests that changes in lifestyle factors could influence the expression of AD in American Indians...
  8. pmc Annualized functional change in Alzheimer's disease participants and normal controls
    Myron Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9129, USA
    Clin Neuropsychol 22:801-6. 2008
    ..5 years. Persons with mild AD showed functional changes over the course of a year on a direct measure of instrumental activities of daily living; a comparable group of normally aging persons did not...
  9. pmc Perspective on race and ethnicity in Alzheimer's disease research
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Alzheimers Dement 4:233-8. 2008
    ....
  10. pmc Brain MRI, apoliprotein E genotype, and plasma homocysteine in American Indian Alzheimer disease patients and Indian controls
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9129, USA
    Curr Alzheimer Res 6:52-8. 2009
    ..In combined AD subjects and controls, WBV correlated with BMI and age. WMHV and WMHV/WBV correlated inversely with MMSE scores (p = 0.001, 0.002, respectively). In addition, WMHV correlated positively with % Indian heritage (p = 0.047)...
  11. ncbi request reprint Can alzheimer's disease and dementias with Lewy bodies be distinguished clinically?
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas 75390 9070, USA
    J Geriatr Psychiatry Neurol 16:245-50. 2003
    ..LB dementias differed from AD at initial evaluation, with more frequent hallucinations and delusions, EPSs, and seizures, and longitudinally in neuroleptic sensitivity, but the data did not distinguish LBV from DLBD...
  12. doi request reprint The relationship of cardiovascular risk factors to Alzheimer disease in Choctaw Indians
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9129, USA
    Am J Geriatr Psychiatry 19:423-9. 2011
    ..In addition to CRF history, the authors investigated the frequency of apolipoprotein E4 (apoE4) genotype andplasma homocysteine (HC) levels...
  13. pmc Luria's three-step test: what is it and what does it tell us?
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Int Psychogeriatr 23:1602-6. 2011
    ..The purpose of this study is to determine if the three-step Luria test is useful for differentiating between cognitive disorders...
  14. ncbi request reprint Assessing Alzheimer's disease patients with the Cohen-Mansfield Agitation Inventory: scoring and clinical implications
    Myron F Weiner
    Departments of Psychiatry and Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9070, USA
    J Psychiatr Res 36:19-25. 2002
    ....
  15. pmc Regional changes of cortical mean diffusivities with aging after correction of partial volume effects
    Tina Jeon
    Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390 8542, USA
    Neuroimage 62:1705-16. 2012
    ..The established comprehensive unbiased cortical MD profiles of young, elderly healthy subjects and AD patients at the lobe, gyral and voxel level may serve as clinical references for cortical microstructure...
  16. pmc Forebrain-dominant deficit in cerebrovascular reactivity in Alzheimer's disease
    Uma S Yezhuvath
    Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Neurobiol Aging 33:75-82. 2012
    ..004). Our data suggest that early AD subjects have evidence of significant forebrain vascular contractility deficits. The localization, while differing from CBF findings, appears to be spatially similar to PIB amyloid imaging findings...
  17. pmc Distinctive disruption patterns of white matter tracts in Alzheimer's disease with full diffusion tensor characterization
    Hao Huang
    Advanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 8542, USA
    Neurobiol Aging 33:2029-45. 2012
    ..High correlation between FA, MD, and RD measurements from limbic tracts and cortical atrophy suggests the disruption of the limbic tract group is caused by the neuronal damage...
  18. ncbi request reprint The effects of gender and CYP46 and apo E polymorphism on 24S-hydroxycholesterol levels in Alzheimer's patients treated with statins
    Gloria Lena Vega
    Department of Clinical Nutrition, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9052, USA
    Curr Alzheimer Res 1:71-7. 2004
    ..Polymorphisms of CYP46 or apo E do not explain levels of oxysterol or non-HDL cholesterol or the responsiveness to statin treatment in this study...
  19. pmc Cerebral blood volume in Alzheimer's disease and correlation with tissue structural integrity
    Jinsoo Uh
    Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States
    Neurobiol Aging 31:2038-46. 2010
    ..These data suggest that the vascular contribution in AD is primarily localized to frontal/parietal white matter and is associated with brain tissue integrity...
  20. pmc Consumer acceptability of brief videoconference-based neuropsychological assessment in older individuals with and without cognitive impairment
    Mili Parikh
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9044, USA
    Clin Neuropsychol 27:808-17. 2013
    ....
  21. ncbi request reprint Comorbidity of psychopathological domains in community-dwelling persons with Alzheimer's disease
    Rochelle E Tractenberg
    Center for Population and Health, Georgetown University, Washington, DC 20057 1197, USA
    J Geriatr Psychiatry Neurol 16:94-9. 2003
    ..Significant psychopathological comorbidity should be considered in the design of clinical trials targeting particular psychopathology in this disease population...
  22. ncbi request reprint Hippocampal volume is associated with memory but not monmemory cognitive performance in patients with mild cognitive impairment
    Michael Grundman
    Department of Neurosciences, University of California, San Diego, La Jolla 92093 0949, USA
    J Mol Neurosci 20:241-8. 2003
    ..We conclude that the relationship between hippocampal volume and risk of AD is likely tied to reduced memory performance and not associated with impairment in nonmemory cognitive domains...
  23. ncbi request reprint Comparison of functional and cognitive donepezil effects in Alzheimer's disease
    Kathleen Saine
    Department of Psychiatry, The University of Texas Southwestern Medical Center at Dallas, 75390 9070, USA
    Int Psychogeriatr 14:181-5. 2002
    ..These results support an effect of donepezil on cognitive measures and day-to-day function and also suggest that the MMSE reflects well the actual functional ability of persons with moderate AD...
  24. doi request reprint Clinical criteria for the diagnosis of Alzheimer disease: still good after all these years
    Najeeb A Ranginwala
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Am J Geriatr Psychiatry 16:384-8. 2008
    ....
  25. ncbi request reprint A direct functional measure to help ascertain optimal level of residential care
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA western edu
    Am J Alzheimers Dis Other Demen 22:355-9. 2007
    ..0001). A TEFA score >50 suggests adequate Functional competence For IL; a score From 30 to 40 adequate Functional competence For AL; and a score oF <30 probable need For an SC unit in the absence oF a capable spouse...
  26. ncbi request reprint Comment on "American Indians/Alaska natives and dementia"
    Myron F Weiner
    Alzheimer Dis Assoc Disord 17:132; author reply 132. 2003
  27. pmc High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial
    Paul S Aisen
    Department of Neurosciences, University of California, San Diego, 9500 Gilman Dr, M C 0949, La Jolla, CA 92093, USA
    JAMA 300:1774-83. 2008
    ..Prior studies of B vitamins to reduce homocysteine in AD have not had sufficient size or duration to assess their effect on cognitive decline...
  28. ncbi request reprint Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease
    Gloria Lena Vega
    Department of Clinical Nutrition, The Center for Human Nutrition, University of Texas Southwestern Medical Center and Nutrition and Metabolism Laboratory, Veterans Affairs Medical Center, Dallas 75390, USA
    Arch Neurol 60:510-5. 2003
    ..Most of plasma 24S-hydroxycholesterol is derived from brain cholesterol; consequently, plasma levels of the oxysterol reflect brain cholesterol catabolism...
  29. ncbi request reprint Caregivers' perceptions of dementia patients' functional ability
    Barbara A Davis
    Department of Neurology, University of Texas Southwestern Medical Center at Dallas, USA
    Am J Alzheimers Dis Other Demen 21:85-91. 2006
    ..Disparities between these estimates and actual patient performance on structured IADL tasks were unrelated to any caregiver, patient, or relationship factor that we measured..
  30. ncbi request reprint Brain MRI hippocampal volume and prediction of clinical status in a mild cognitive impairment trial
    Michael Grundman
    Department of Neurosciences, University of California, San Diego, La Jolla, USA
    J Mol Neurosci 19:23-7. 2002
    ..In summary, these data suggest that MRI hippocampal volume may be a useful correlate of disease severity in MCI subjects and a prognostic indicator of subsequent AD...
  31. ncbi request reprint No long-term effect of behavioral treatment on psychotropic drug use for agitation in Alzheimer's disease patients
    Myron F Weiner
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, USA
    J Geriatr Psychiatry Neurol 15:95-8. 2002
    ..0 for subjects in each drug arm or placebo arm versus BMTs. We concluded that teaching caregivers BMTs did not diminish long-term prescription of psychotropic drugs...
  32. ncbi request reprint Emergent psychopathology in Alzheimer's disease patients over 12 months associated with functional, not cognitive, changes
    Rochelle E Tractenberg
    Department of Neurosciences, University of California, San Diego, La Jolla 92093 0949, USA
    J Geriatr Psychiatry Neurol 15:110-7. 2002
    ....
  33. ncbi request reprint Estimating the prevalence of agitation in community-dwelling persons with Alzheimer's disease
    Rochelle E Tractenberg
    Alzheimer s Disease Cooperative Study, Department of Neurosciences, University of California, San Diego, La Jolla 92093 0949, USA
    J Neuropsychiatry Clin Neurosci 14:11-8. 2002
    ..The authors conclude that the best estimate of prevalence of excessive agitation in this population is 67.5%, and that individuals with CMAI scores of 0 to 14 probably should not be considered to have excessive agitation...
  34. ncbi request reprint Reduced hippocampal functional connectivity in Alzheimer disease
    Greg Allen
    Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9127, USA
    Arch Neurol 64:1482-7. 2007
    ..To determine if functional connectivity of the hippocampus is reduced in patients with Alzheimer disease...
  35. ncbi request reprint Plasma 24S hydroxycholesterol response to statins in Alzheimer's disease patients: effects of gender, CYP46, and ApoE polymorphisms
    Gloria Lena Vega
    The Nutrition and Metabolism Laboratory, Metabolic Unit, Veterans Affairs Medical Center, Dallas, TX 75390, USA
    J Mol Neurosci 33:51-5. 2007
    ..There were no untoward effects of the standard doses of statin for the duration of treatment. Statins are currently in trial to determine their effect on the course of AD...
  36. ncbi request reprint Effects of cognitive-communication stimulation for Alzheimer's disease patients treated with donepezil
    Sandra Bond Chapman
    The University of Texas at Dallas, USA
    J Speech Lang Hear Res 47:1149-63. 2004
    ..The fact that AD is a progressive brain disease should not preclude ameliorative treatment...
  37. ncbi request reprint Independence of changes in behavior from cognition and function in community-dwelling persons with Alzheimer's disease: a factor analytic approach
    Rochelle E Tractenberg
    Department of Biomathematics and Biostatistics, Georgetown University School of Medicine, 7 East Main, M702, Georgetown University Hospital, 3800 Reservoir Rd, NW, Washington, DC 20007, USA
    J Neuropsychiatry Clin Neurosci 17:51-60. 2005
    ..Cognitive and functional subscores for the CDR were supported. These findings suggest that changes in behavior and cognition in dementia may have distinct pathophysiologies...
  38. ncbi request reprint Performance of elderly Native Americans and Caucasians on the CERAD Neuropsychological Battery
    Shannon R Whyte
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8846, USA
    Alzheimer Dis Assoc Disord 19:74-8. 2005
    ..However, additional studies of larger samples are needed for confirmation and to explore factors such as education, acculturation, and degree of Native American heritage, which may influence cognitive test performance...
  39. ncbi request reprint Sex, apolipoprotein E epsilon 4 status, and hippocampal volume in mild cognitive impairment
    Adam Fleisher
    Department of Neurosciences, University of California San Diego, La Jolla, Calif, USA
    Arch Neurol 62:953-7. 2005
    ..The presence of the apolipoprotein E epsilon4 (APOE*E4) allele has been associated with greater hippocampal atrophy in women than in men with Alzheimer disease. This relationship has not been demonstrated in MCI...
  40. ncbi request reprint Levetiracetam for agitated Alzheimer's disease patients
    Myron F Weiner
    Int Psychogeriatr 17:327-8. 2005
  41. ncbi request reprint FMRI of working memory in patients with mild cognitive impairment and probable Alzheimer's disease
    F Zerrin Yetkin
    Department of Radiology and Alzheimer s Disease Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 8896, USA
    Eur Radiol 16:193-206. 2006
    ..The WM task evoked activation in widely distributed regions, consistent with previous fMRI studies. AD and MCI patients showed an increased extent of activation and recruitment of additional areas...
  42. ncbi request reprint Responsiveness of the quality of life in late-stage dementia scale to psychotropic drug treatment in late-stage dementia
    Kristin Martin-Cook
    University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9070, USA
    Dement Geriatr Cogn Disord 19:82-5. 2005
    ..We report on the responsiveness of a previously validated quality-of-life scale, the Quality of Life in Late-Stage Dementia scale (QUALID), as an outcome measure in a clinical trial of two psychotropic medications...
  43. ncbi request reprint Vascular disease and risk factors, rate of progression, and survival in Alzheimer's disease
    Deepika Bhargava
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9070, USA
    J Geriatr Psychiatry Neurol 19:78-82. 2006
    ....
  44. ncbi request reprint Patterns of verbal memory performance in mild cognitive impairment, Alzheimer disease, and normal aging
    Melanie C Greenaway
    Department of Psychiatry and Psychology, The Mayo Clinic, Rochester, USA
    Cogn Behav Neurol 19:79-84. 2006
    ..Individuals with mild cognitive impairment (MCI) typically demonstrate memory loss that falls between normal aging (NA) and Alzheimer disease (AD), but little is known about the pattern of memory dysfunction in MCI...
  45. ncbi request reprint ADCS Prevention Instrument Project: quality of life assessment (QOL)
    Marian B Patterson
    Case Western Reserve University, Cleveland, OH, USA
    Alzheimer Dis Assoc Disord 20:S179-90. 2006
    ..We conclude that the QOL scores at baseline show sufficient range and reliability to suggest they will have utility in tracking QOL through conversion to dementia...
  46. ncbi request reprint Feasibility of telecognitive assessment in dementia
    C Munro Cullum
    University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA
    Assessment 13:385-90. 2006
    ..Furthermore, continued development of VC technology has implications for expanding neuropsychological assessment options in under-served populations...
  47. ncbi request reprint Risk factors for potentially harmful informal caregiver behavior
    Scott R Beach
    University Center for Social and Urban Research, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Am Geriatr Soc 53:255-61. 2005
    ..This article explores such risk factors...
  48. ncbi request reprint Caregiver attribution and resentment in dementia care
    Kristin Martin-Cook
    Department of Psychiatry, Alzheimer s Disease Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Am J Alzheimers Dis Other Demen 18:366-74. 2003
    ..These results are discussed in relation to existing research on caregiver distress and intervention...
  49. doi request reprint Disease-modifying therapies in Alzheimer's disease
    Stephen Salloway
    Department of Clinical Neuroscience, Division of Biology and Medicine, Brown Medical School, Providence, RI, USA
    Alzheimers Dement 4:65-79. 2008
    ..Potentially neuroprotective and restorative treatments such as neurotrophins, neurotrophic factor enhancers, and stem cell-related approaches are also under investigation...
  50. ncbi request reprint Measuring QOL in dementia
    Myron F Weiner
    Int Psychogeriatr 18:357-8; author reply 358-9. 2006
  51. ncbi request reprint A randomized, controlled study of an Alzheimer's caregiver skills training program
    Kristin Martin-Cook
    Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
    Am J Alzheimers Dis Other Demen 20:204-10. 2005
    ..We didfind the expected relationship between depression and caregiver sense of self-efficacy...
  52. ncbi request reprint A double-blind comparison of olanzapine versus risperidone in the acute treatment of dementia-related behavioral disturbances in extended care facilities
    Catherine S Fontaine
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas 75390 9070, USA
    J Clin Psychiatry 64:726-30. 2003
    ....
  53. ncbi request reprint Benchmarking a test of temporal orientation with data from american and taiwanese persons with Alzheimer's disease and american normal elderly
    Rochelle E Tractenberg
    Department of Biomathematics and Biostatistics, Georgetown University School of Medicine, Washington, DC 20008, USA
    Neuroepidemiology 24:110-6. 2005
    ..TTO may be a useful component of cognitive screening efforts...
  54. ncbi request reprint Three-word recall in normal aging
    Melanie J Chandler
    The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 8846, USA
    J Clin Exp Neuropsychol 26:1128-33. 2004
    ..This is in stark contrast to the 87% of individuals with AD who recalled 0 or 1 word. Even though 3-word recall performance decreases with age, good recall (2 or 3 words) can be expected in most cases of normal aging...