Carl P Weiner

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi request reprint Proteomic biomarkers that predict the clinical success of rescue cerclage
    Carl P Weiner
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD 21201 1559, USA
    Am J Obstet Gynecol 192:710-8. 2005
  2. ncbi request reprint Detection of viral deoxyribonucleic acid in amniotic fluid: association with fetal malformation and pregnancy abnormalities
    Uma M Reddy
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD 21201 1703, USA
    Fetal Diagn Ther 20:203-7. 2005
  3. ncbi request reprint Biomechanical properties of the lower uterine segment above and below the reflection of the urinary bladder flap
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University, New Haven, Connecticut 06520, USA
    Obstet Gynecol 109:691-700. 2007
  4. ncbi request reprint The effect of fundal pressure manoeuvre on intrauterine pressure in the second stage of labour
    Catalin S Buhimschi
    Department of Obstetrics, Gynaecology and Reproductive Sciences, The University of Maryland School of Medicine, Baltimore, USA
    BJOG 109:520-6. 2002
  5. ncbi request reprint Intrauterine pressure during the second stage of labor in obese women
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA
    Obstet Gynecol 103:225-30. 2004
  6. ncbi request reprint Proteomics, part II: the emerging role of proteomics over genomics in spontaneous preterm labor/birth
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Science, Yale University School of Medicine, New Haven, Connecticut 06520 8063, USA
    Obstet Gynecol Surv 61:543-53. 2006
  7. ncbi request reprint Uterine contractility in women whose fetus is delivered in the occipitoposterior position
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Wayne State University, Detroit, Mich 48201, USA
    Am J Obstet Gynecol 188:734-9. 2003
  8. ncbi request reprint Myometrial thickness during human labor and immediately post partum
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Wayne State University, Detroit, MI 48201, USA
    Am J Obstet Gynecol 188:553-9. 2003
  9. ncbi request reprint Beneficial impact of term labor: nonenzymatic antioxidant reserve in the human fetus
    Irina A Buhimschi
    Departments of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
    Am J Obstet Gynecol 189:181-8. 2003
  10. pmc Uterine and fetal blood flow indexes and fetal growth assessment after chronic estrogen suppression in the second half of baboon pregnancy
    Graham W Aberdeen
    Dept of Obstetrics, Gynecology and Reproductive Sciences, Univ of Maryland School of Medicine, Baltimore, MD 21201, USA
    Am J Physiol Heart Circ Physiol 298:H881-9. 2010

Detail Information

Publications32

  1. ncbi request reprint Proteomic biomarkers that predict the clinical success of rescue cerclage
    Carl P Weiner
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD 21201 1559, USA
    Am J Obstet Gynecol 192:710-8. 2005
    ..We tested amniotic fluid from women who were preparing to undergo rescue cerclage for proteomic biomarkers and correlated their presence with clinical outcome...
  2. ncbi request reprint Detection of viral deoxyribonucleic acid in amniotic fluid: association with fetal malformation and pregnancy abnormalities
    Uma M Reddy
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD 21201 1703, USA
    Fetal Diagn Ther 20:203-7. 2005
    ....
  3. ncbi request reprint Biomechanical properties of the lower uterine segment above and below the reflection of the urinary bladder flap
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University, New Haven, Connecticut 06520, USA
    Obstet Gynecol 109:691-700. 2007
    ..To test the hypothesis that differences in the matrix arrangement of the lower uterine segment (above and below the reflection of the bladder flap) translate to differences in biomechanical or structural properties of the uterine wall...
  4. ncbi request reprint The effect of fundal pressure manoeuvre on intrauterine pressure in the second stage of labour
    Catalin S Buhimschi
    Department of Obstetrics, Gynaecology and Reproductive Sciences, The University of Maryland School of Medicine, Baltimore, USA
    BJOG 109:520-6. 2002
    ..To investigate the relationship between intrauterine pressure and the application of a standardised fundal pressure manoeuvre, and to determine the maternal, fetal and labour characteristics that modulate the relationship...
  5. ncbi request reprint Intrauterine pressure during the second stage of labor in obese women
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA
    Obstet Gynecol 103:225-30. 2004
    ..We tested the hypothesis that obese women generate inadequate intrauterine pressure during the second stage of labor...
  6. ncbi request reprint Proteomics, part II: the emerging role of proteomics over genomics in spontaneous preterm labor/birth
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Science, Yale University School of Medicine, New Haven, Connecticut 06520 8063, USA
    Obstet Gynecol Surv 61:543-53. 2006
    ..Thus, it provides the ability to identify patients who may benefit from interventions in utero in a modern diagnostic-therapeutic framework...
  7. ncbi request reprint Uterine contractility in women whose fetus is delivered in the occipitoposterior position
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Wayne State University, Detroit, Mich 48201, USA
    Am J Obstet Gynecol 188:734-9. 2003
    ..We sought to test the hypothesis that women with a persistent occipitoposterior fetal position have inadequate intrauterine pressure...
  8. ncbi request reprint Myometrial thickness during human labor and immediately post partum
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Wayne State University, Detroit, MI 48201, USA
    Am J Obstet Gynecol 188:553-9. 2003
    ..This growth is most marked at the fundus. Our objective was to evaluate sonographically the in vivo changes in myometrial thickness during active labor, second-stage labor, and after delivery...
  9. ncbi request reprint Beneficial impact of term labor: nonenzymatic antioxidant reserve in the human fetus
    Irina A Buhimschi
    Departments of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
    Am J Obstet Gynecol 189:181-8. 2003
    ..We tested aspects of this hypothesis by investigating whether the presence of labor or gestational age at delivery (term vs preterm) alters the maternal/fetal nonenzymatic antioxidant reserve peripartum...
  10. pmc Uterine and fetal blood flow indexes and fetal growth assessment after chronic estrogen suppression in the second half of baboon pregnancy
    Graham W Aberdeen
    Dept of Obstetrics, Gynecology and Reproductive Sciences, Univ of Maryland School of Medicine, Baltimore, MD 21201, USA
    Am J Physiol Heart Circ Physiol 298:H881-9. 2010
    ..This suggests that elevated levels of endogenous estrogen are not required to maintain low impedance blood flow within the uteroplacental vascular bed during the second half of nonhuman primate pregnancy...
  11. ncbi request reprint The effect of dystocia and previous cesarean uterine scar on the tensile properties of the lower uterine segment
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University, New Haven, CT 06520, USA
    Am J Obstet Gynecol 194:873-83. 2006
    ..We hypothesized that the stretching of the lower uterine segment in laboring women with dystocia changes the viscoelastic properties of the uterine wall...
  12. ncbi request reprint Effects of sublingual nitroglycerin on human uterine contractility during the active phase of labor
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, USA
    Am J Obstet Gynecol 187:235-8. 2002
    ..If a clinical option, sublingual nitroglycerin will require a higher dose, which would place mother and fetus at risk for complication...
  13. ncbi request reprint Venous Doppler in the prediction of acid-base status of growth-restricted fetuses with elevated placental blood flow resistance
    Ahmet A Baschat
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland, Baltimore 21201 1703, USA
    Am J Obstet Gynecol 191:277-84. 2004
    ..This study was undertaken to test which venous Doppler parameter offers the best prediction of acid-base status at birth in pregnancies complicated by intrauterine growth restriction (IUGR) caused by placental dysfunction...
  14. pmc ATP-binding cassette transporter expression in human placenta as a function of pregnancy condition
    Cifford W Mason
    Department of Pharmaceutical Sciences, University of Maryland, Baltimore, MD 21201, USA
    Drug Metab Dispos 39:1000-7. 2011
    ..These data suggest that the transfer of drugs across the placenta may be altered in preterm pregnancy conditions associated with inflammation through changes in MDR1 and BCRP...
  15. ncbi request reprint Rupture of the uterine scar during term labour: contractility or biochemistry?
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, New Haven, CT 06520, USA
    BJOG 112:38-42. 2005
    ..We hypothesised that similar to the cervix, prostaglandins induces biochemical changes in the uterine scar favouring dissolution, predisposing the uterus to rupture at the scar of the lower segment as opposed to elsewhere...
  16. ncbi request reprint The presence and function of phosphodiesterase type 5 in the rat myometrium
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University, New Haven, CT 06520, USA
    Am J Obstet Gynecol 190:268-74. 2004
    ..The type 5 isoform (PDE-5, cGMP specific) is the target of specific antagonists (ie, sildenafil, Viagra). We tested the hypothesis that PDE-5 is present in rat myometrium and modulates myometrial activity...
  17. ncbi request reprint Clinical proteomics: a novel diagnostic tool for the new biology of preterm labor, part I: proteomics tools
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Science, Yale University School of Medicine, New Haven, Connecticut 06520 8063, USA
    Obstet Gynecol Surv 61:481-6. 2006
    ..Interest in mass spectrometry and its use as a new clinical diagnostic tool has grown rapidly and is poised to become an important medical field for the next century...
  18. pmc Characterization of RAGE, HMGB1, and S100beta in inflammation-induced preterm birth and fetal tissue injury
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, 333 Cedar Street, New Haven, CT 06520, USA
    Am J Pathol 175:958-75. 2009
    ..Our findings indicate that RAGE and HMGB1 may be important mediators of cellular injury in fetuses delivered in the setting of inflammation-induced preterm birth...
  19. ncbi request reprint Identification of interactive gene networks: a novel approach in gene array profiling of myometrial events during guinea pig pregnancy
    Clifford W Mason
    Department of Pharmaceutical Science, University of Maryland School of Pharmacy, Baltimore, MD, USA
    Am J Obstet Gynecol 194:1513-23. 2006
    ..We applied functional analysis and logical operations along regulatory gene networks to identify molecular processes and pathways underlying quiescence and activation...
  20. pmc Proteomic but not enzyme-linked immunosorbent assay technology detects amniotic fluid monomeric calgranulins from their complexed calprotectin form
    Irina A Buhimschi
    Department of Obstetrics, Gynecology, and Reproductive Science, Yale University School of Medicine, 333 Cedar Street LCI 804, P O Box 208063, New Haven, CT 06520 8063, USA
    Clin Diagn Lab Immunol 12:837-44. 2005
    ..Monomeric Cal-A is not reliably estimated by specific ELISA as it binds to Cal-B to form the calprotectin complex. Cal-C was reliably measured by SELDI-TOF mass spectrometry or specific ELISA...
  21. ncbi request reprint Is adenovirus a fetal pathogen?
    Ahmet A Baschat
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Center for Advanced Fetal Care, University of Maryland, Baltimore 21201, USA
    Am J Obstet Gynecol 189:758-63. 2003
    ..The purpose of this study was to test the relationship between adenovirus genetic material in the amniotic fluid and adverse pregnancy outcome...
  22. ncbi request reprint Kleihauer-betke testing is important in all cases of maternal trauma
    Michael V Muench
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Trauma 57:1094-8. 2004
    ..Reasoning that the magnitude of TPH would reflect uterine injury, we evaluated Kleihauer-Betke testing as an independent predictor of preterm labor (PTL) after maternal trauma...
  23. ncbi request reprint The novel antimicrobial peptide beta3-defensin is produced by the amnion: a possible role of the fetal membranes in innate immunity of the amniotic cavity
    Irina A Buhimschi
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University, New Haven, Conn, USA
    Am J Obstet Gynecol 191:1678-87. 2004
    ..The ability of the amnion cells, which are epithelial derivatives, to produce antimicrobial beta-defensins has not been explored...
  24. ncbi request reprint Chorion-induced myometrial relaxation is mediated by large-conductance Ca2+-activated K+ channel opening in the guinea pig
    Jorge A Carvajal
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD 21201, USA
    Am J Obstet Gynecol 188:84-91. 2003
    ..We previously demonstrated that chorion releases a factor that inhibits both spontaneous and oxytocin-stimulated myometrial contractility. Here, we investigate the mechanism of action of this unidentified substance...
  25. ncbi request reprint Physical and biomechanical characteristics of rat cervical ripening are not consistent with increased collagenase activity
    Irina A Buhimschi
    Department of Obstetrics, Gynecology, and Reproductive Science, Yale University School of Medicine, New Haven, Conn, USA
    Am J Obstet Gynecol 191:1695-704. 2004
    ....
  26. ncbi request reprint Protective effect of N-acetylcysteine against fetal death and preterm labor induced by maternal inflammation
    Irina A Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
    Am J Obstet Gynecol 188:203-8. 2003
    ..We tested aspects of this hypothesis in an animal model of preterm labor and fetal damage (death)...
  27. ncbi request reprint Pushing in labor: performance and not endurance
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, The University of Maryland School of Medicine, Baltimore, USA
    Am J Obstet Gynecol 186:1339-44. 2002
    ....
  28. doi request reprint Medications in pregnancy and lactation: Part 2. Drugs with minimal or unknown human teratogenic effect
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Science, Yale University School of Medicine, New Haven, CT 06520, USA
    Obstet Gynecol 113:417-32. 2009
    ....
  29. doi request reprint Medications in pregnancy and lactation: part 1. Teratology
    Catalin S Buhimschi
    Department of Obstetrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Obstet Gynecol 113:166-88. 2009
    ....
  30. pmc Proteomic profiling of the amniotic fluid to detect inflammation, infection, and neonatal sepsis
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Science, Yale University School of Medicine, New Haven, Connecticut, United States of America
    PLoS Med 4:e18. 2007
    ..Proteomic analysis of amniotic fluid shows the presence of biomarkers characteristic of intrauterine inflammation. We sought to validate prospectively the clinical utility of one such proteomic profile, the Mass Restricted (MR) score...
  31. ncbi request reprint Proteomics technology for the accurate diagnosis of inflammation in twin pregnancies
    Irina A Buhimschi
    Yale University School of Medicine, New Haven, Connecticut 06520 8063, USA
    BJOG 112:250-5. 2005
  32. ncbi request reprint Proteomic Profiling and Intra-amniotic Infection
    Irina A Buhimschi
    JAMA 292:2338; author reply 2338-9. 2004