NORMAN WEINBERGER

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Specific long-term memory traces in primary auditory cortex
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory and Department of Neurobiology and Behavior, University of California Irvine, Irvine, California 92797 3800, USA
    Nat Rev Neurosci 5:279-90. 2004
  2. ncbi request reprint Posttraining handling facilitates memory for auditory-cue fear conditioning in rats
    Isabel R Hui
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 86:160-3. 2006
  3. pmc The level of cholinergic nucleus basalis activation controls the specificity of auditory associative memory
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 86:270-85. 2006
  4. pmc Avoidance learning facilitates temporal processing in the primary auditory cortex
    Matthew I Leon
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, 309 Qureshey Research Laboratory, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 90:347-57. 2008
  5. pmc Gamma band plasticity in sensory cortex is a signature of the strongest memory rather than memory of the training stimulus
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 104:49-63. 2013
  6. pmc Sensory memory consolidation observed: increased specificity of detail over days
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 91:273-86. 2009
  7. ncbi request reprint Food for thought: honeybee foraging, memory, and acetylcholine
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA
    Sci STKE 2006:pe23. 2006
  8. ncbi request reprint The nucleus basalis and memory codes: auditory cortical plasticity and the induction of specific, associative behavioral memory
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, University of California Irvine, Irvine, CA 92797 3800, USA
    Neurobiol Learn Mem 80:268-84. 2003
  9. pmc Associative representational plasticity in the auditory cortex: a synthesis of two disciplines
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, and Department of Neurobiology and Behavior, University of California, Irvine, California 92697 3800, USA
    Learn Mem 14:1-16. 2007
  10. pmc Auditory associative memory and representational plasticity in the primary auditory cortex
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92797 3800, USA
    Hear Res 229:54-68. 2007

Research Grants

  1. EMOTION AND RETUNING OF AUDITORY CORTEX
    NORMAN WEINBERGER; Fiscal Year: 2002
  2. The amygdala & cortical receptive field plasticity
    NORMAN WEINBERGER; Fiscal Year: 2006
  3. DYNAMIC REGULATION OF TUNING IN ADULT AUDITORY CORTEX
    NORMAN WEINBERGER; Fiscal Year: 2007
  4. DYNAMIC REGULATION OF TUNING IN ADULT AUDITORY CORTEX
    Norman M Weinberger; Fiscal Year: 2010
  5. LEARNING-INDUCED CORTICAL REPRESENTATIONAL PLASTICITY
    NORMAN WEINBERGER; Fiscal Year: 2001
  6. DYNAMIC REGULATION OF TUNING IN ADULT AUDITORY CORTEX
    NORMAN WEINBERGER; Fiscal Year: 2001
  7. EMOTION AND RETUNING OF AUDITORY CORTEX
    NORMAN WEINBERGER; Fiscal Year: 1993
  8. Functions of Associative Auditory Cortical Plasticity
    Norman M Weinberger; Fiscal Year: 2010

Collaborators

  • James L McGaugh
  • RAJU S METHERATE
  • Richard G Rutkowski
  • B Roozendaal
  • Alexandre A Miasnikov
  • Kasia M Bieszczad
  • Gabriel K Hui
  • Dewey E McLin
  • Jemmy C Chen
  • Kevin Liang
  • Candice M Chavez
  • Matthew I Leon
  • Bonnie S Poytress
  • Veronica V Galvan
  • Kasia M Berlau
  • Bonnie Sue Poytress
  • Isabel R Hui
  • Kwan L Wong
  • Kinna M Robin
  • Nataliya Gross
  • Yiling Chen
  • Frances M Leslie
  • Isabel R Figueroa
  • Jemmy Chen

Detail Information

Publications33

  1. pmc Specific long-term memory traces in primary auditory cortex
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory and Department of Neurobiology and Behavior, University of California Irvine, Irvine, California 92797 3800, USA
    Nat Rev Neurosci 5:279-90. 2004
  2. ncbi request reprint Posttraining handling facilitates memory for auditory-cue fear conditioning in rats
    Isabel R Hui
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 86:160-3. 2006
    ..These findings thus indicate that the posttraining injection or handling procedure is sufficiently arousing or stressful to facilitate memory consolidation of auditory-cue classical fear conditioning...
  3. pmc The level of cholinergic nucleus basalis activation controls the specificity of auditory associative memory
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 86:270-85. 2006
    ..The findings demonstrate that the amount of detail in memory can be directly controlled by neural intervention...
  4. pmc Avoidance learning facilitates temporal processing in the primary auditory cortex
    Matthew I Leon
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, 309 Qureshey Research Laboratory, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 90:347-57. 2008
    ..The facilitation of temporal processing suggests that avoidance learning may increase synaptic strength either within the auditory cortex, in the subcortical auditory system, or both...
  5. pmc Gamma band plasticity in sensory cortex is a signature of the strongest memory rather than memory of the training stimulus
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 104:49-63. 2013
    ..These findings indicate that the strength of specific increased neuronal synchronization within primary sensory cortical fields can determine the specific contents of memory...
  6. pmc Sensory memory consolidation observed: increased specificity of detail over days
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 91:273-86. 2009
    ..These findings indicate that the sensory contents of associative memory can be revealed to become more specific, through temporal consolidation in the absence of non-sensory factors such as motivation and emotion...
  7. ncbi request reprint Food for thought: honeybee foraging, memory, and acetylcholine
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA
    Sci STKE 2006:pe23. 2006
    ....
  8. ncbi request reprint The nucleus basalis and memory codes: auditory cortical plasticity and the induction of specific, associative behavioral memory
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, University of California Irvine, Irvine, CA 92797 3800, USA
    Neurobiol Learn Mem 80:268-84. 2003
    ....
  9. pmc Associative representational plasticity in the auditory cortex: a synthesis of two disciplines
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, and Department of Neurobiology and Behavior, University of California, Irvine, California 92697 3800, USA
    Learn Mem 14:1-16. 2007
    ..The advantages of studying associative representational plasticity are emphasized, as is the need for greater behavioral sophistication...
  10. pmc Auditory associative memory and representational plasticity in the primary auditory cortex
    Norman M Weinberger
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92797 3800, USA
    Hear Res 229:54-68. 2007
    ..Future research needs to focus on the factors that determine ARP and their functions in hearing and in auditory memory...
  11. pmc The medial geniculate, not the amygdala, as the root of auditory fear conditioning
    Norman M Weinberger
    309 Qureshey Research Laboratory, Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Hear Res 274:61-74. 2011
    ..Synaptic and molecular approaches supporting the AL also implicate the MGm/PIN. As both the AL and its preceding MGm/PIN are critically involved, we propose that the latter be considered the "root" of AFC...
  12. pmc Motivationally neutral stimulation of the nucleus basalis induces specific behavioral memory
    Alexandre A Miasnikov
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 90:125-37. 2008
    ..These results are concordant with a memory-promoting role for the nucleus basalis that places it "downstream" of motivational systems, which activate it to initiate the storage of the current state of its cholinergic targets...
  13. pmc Specific auditory memory induced by nucleus basalis stimulation depends on intrinsic acetylcholine
    Alexandre A Miasnikov
    Center for the Neurobiology of Learning and Memory, 309 Qureshey Research Laboratory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 90:443-54. 2008
    ....
  14. pmc Rapid induction of specific associative behavioral memory by stimulation of the nucleus basalis in the rat
    Alexandre A Miasnikov
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 86:47-65. 2006
    ....
  15. pmc Induction of behavioral associative memory by stimulation of the nucleus basalis
    Dewey E McLin
    Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Proc Natl Acad Sci U S A 99:4002-7. 2002
    ..The discovery of memory induction by direct activation of the NB supports the NB-memory hypothesis and provides a potentially powerful way to control and investigate neural mechanisms of memory...
  16. pmc Remodeling the cortex in memory: Increased use of a learning strategy increases the representational area of relevant acoustic cues
    Kasia M Bieszczad
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California Irvine, CA 92697 3800, United States
    Neurobiol Learn Mem 94:127-44. 2010
    ..Together, the findings indicate that the amount of strategy use is a dominant factor for the induction of learning-induced cortical plasticity along a continuum of both form and degree...
  17. pmc Behavioral memory induced by stimulation of the nucleus basalis: effects of contingency reversal
    Alexandre A Miasnikov
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, United States
    Neurobiol Learn Mem 91:298-309. 2009
    ....
  18. pmc Learning strategy trumps motivational level in determining learning-induced auditory cortical plasticity
    Kasia M Bieszczad
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, United States
    Neurobiol Learn Mem 93:229-39. 2010
    ..Thus, type of learning strategy, not level of learning or motivation, is dominant for the formation of cortical plasticity...
  19. pmc Conditioned tone control of brain reward behavior produces highly specific representational gain in the primary auditory cortex
    Gabriel K Hui
    Qureshey Research Laboratory, Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 92:27-34. 2009
    ....
  20. ncbi request reprint CS-specific gamma, theta, and alpha EEG activity detected in stimulus generalization following induction of behavioral memory by stimulation of the nucleus basalis
    Dewey E McLin
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 79:152-76. 2003
    ..Thus, stimulus generalization tests reveal that conditioned EEG activation is not unitary but rather reflects CS-specificity, with band-selective markers for specific, associative neural processes in learning and memory...
  21. pmc Representational gain in cortical area underlies increase of memory strength
    Kasia M Bieszczad
    Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Proc Natl Acad Sci U S A 107:3793-8. 2010
    ..These findings indicate that specific gain in cortical representational area underlies the strength of the behaviorally-relevant contents of memory. Thus, mnemonic functions of cortical plasticity are determinable...
  22. pmc Learning strategy determines auditory cortical plasticity
    Kasia M Berlau
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92797 3800, USA
    Neurobiol Learn Mem 89:153-66. 2008
    ..that the representation of specific acquired information may be selected by neurons according to a match between behaviorally selected stimulus features and circuit/network response properties...
  23. pmc Nicotinic modulation of tone-evoked responses in auditory cortex reflects the strength of prior auditory learning
    Kevin Liang
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, Center for Hearing Research, University of California, Irvine, CA 92697, USA
    Neurobiol Learn Mem 90:138-46. 2008
    ..Our findings suggest that nicotinic regulation of cortical receptive fields may be a distinguishing feature of the best-performing animals, and may facilitate sensory-related learning by enhancing receptive field selectivity...
  24. pmc The basolateral amygdala modulates specific sensory memory representations in the cerebral cortex
    Candice M Chavez
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California Irvine, Qureshey Research Laboratory, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 91:382-92. 2009
    ..These findings suggest that the ability of the BLA to alter specific cortical representations may underlie, at least in part, the modulatory influence of BLA activity on strengthening long-term memory...
  25. ncbi request reprint Long-term consolidation and retention of learning-induced tuning plasticity in the auditory cortex of the guinea pig
    Veronica V Galvan
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, Irvine, California 92797 3800, USA
    Neurobiol Learn Mem 77:78-108. 2002
    ..Potential cellular and subcellular mechanisms of LFP tuning plasticity and long-term consolidation are discussed...
  26. ncbi request reprint Characterisation of multiple physiological fields within the anatomical core of rat auditory cortex
    Richard G Rutkowski
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697, USA
    Hear Res 181:116-30. 2003
    ..Both A1 and AAF were located within temporal cortex 1 (Te1), with AAF occupying an anteroventral subdivision of Te1, indicating that the two neighbouring, physiologically distinct fields are cytoarchitectonically homogeneous...
  27. ncbi request reprint Memory enhancement of classical fear conditioning by post-training injections of corticosterone in rats
    Gabriel K Hui
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 81:67-74. 2004
    ....
  28. pmc Encoding of learned importance of sound by magnitude of representational area in primary auditory cortex
    Richard G Rutkowski
    Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697 3800, USA
    Proc Natl Acad Sci U S A 102:13664-9. 2005
    ..Overall, the findings support the encoding of acquired stimulus importance based on representational size in AI...
  29. ncbi request reprint Basolateral amygdala noradrenergic activity mediates corticosterone-induced enhancement of auditory fear conditioning
    Benno Roozendaal
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 86:249-55. 2006
    ....
  30. ncbi request reprint The effects of electrical stimulation of the nucleus basalis on the electroencephalogram, heart rate, and respiration
    Dewey E McLin
    Center for the Neurobiology of Learning and Memory and Department of Neurobiology and Behavior, University of California, Irvine 92697 3800, USA
    Behav Neurosci 116:795-806. 2002
    ..Neither EEG nor behavioral effects exhibited habituation or facilitation. These results indicate that the NB may serve not only as a cortical, but also as a behavioral, activation system that is normally engaged during learning...
  31. ncbi request reprint Neonatal nicotine exposure impairs nicotinic enhancement of central auditory processing and auditory learning in adult rats
    Kevin Liang
    Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA
    Eur J Neurosci 24:857-66. 2006
    ....
  32. ncbi request reprint Differential thresholds of local field potentials and unit discharges in rat auditory cortex
    Veronica V Galvan
    Department of Neurobiology and Behavior and 309 Qureshey Research Laboratory, Center for the Neurobiology of Learning and Memory, University of California Irvine, 92697 3800, USA
    Hear Res 167:57-60. 2002
    ..The findings are consistent with the view that local field potentials in the auditory cortex reflect summed synaptic potentials rather than cellular discharges...
  33. ncbi request reprint Music and the brain
    Norman M Weinberger
    Department of Neurobiology and Behavior, University of California, Irvine, USA
    Sci Am 291:88-95. 2004

Research Grants34

  1. EMOTION AND RETUNING OF AUDITORY CORTEX
    NORMAN WEINBERGER; Fiscal Year: 2002
    ....
  2. The amygdala & cortical receptive field plasticity
    NORMAN WEINBERGER; Fiscal Year: 2006
    ..abstract_text> ..
  3. DYNAMIC REGULATION OF TUNING IN ADULT AUDITORY CORTEX
    NORMAN WEINBERGER; Fiscal Year: 2007
    ..abstract_text> ..
  4. DYNAMIC REGULATION OF TUNING IN ADULT AUDITORY CORTEX
    Norman M Weinberger; Fiscal Year: 2010
    ....
  5. LEARNING-INDUCED CORTICAL REPRESENTATIONAL PLASTICITY
    NORMAN WEINBERGER; Fiscal Year: 2001
    ....
  6. DYNAMIC REGULATION OF TUNING IN ADULT AUDITORY CORTEX
    NORMAN WEINBERGER; Fiscal Year: 2001
    ..Additionally, this project will provide a basis for understanding learning to perceive speech following cochlear implants in the deaf and recently identified learning-based remediation of temporal processing deficits in dyslexia. ..
  7. EMOTION AND RETUNING OF AUDITORY CORTEX
    NORMAN WEINBERGER; Fiscal Year: 1993
    ..These findings will provide the firs systematic analysis of how information itself which is specific to fear stimuli is processed and stored in the cerebral cortex...
  8. Functions of Associative Auditory Cortical Plasticity
    Norman M Weinberger; Fiscal Year: 2010
    ..The findings will be directly relevant to the design and implementation of therapeutic interventions, to enable and improve general auditory and speech comprehension. ..