Adriana Weinberg

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc Virologic and immunologic correlates with the magnitude of antibody responses to the hepatitis A vaccine in HIV-infected children on highly active antiretroviral treatment
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Denver, Aurora, CO 80045, USA
    J Acquir Immune Defic Syndr 52:17-24. 2009
  2. pmc Kinetics and determining factors of the virologic response to antiretrovirals during pregnancy
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    Infect Dis Obstet Gynecol 2009:621780. 2009
  3. pmc Pandemic influenza A H1N1 2009 infection versus vaccination: a cohort study comparing immune responses in pregnancy
    Barbra M Fisher
    Department of Obstetrics and Gynecology, Section of Maternal Fetal Medicine, University of Colorado School of Medicine, Aurora, Colorado, United States of America
    PLoS ONE 7:e33048. 2012
  4. pmc Dynamics of regulatory T-cells during pregnancy: effect of HIV infection and correlations with other immune parameters
    Kelly Richardson
    Department of Pediatrics, University of Colorado Denver, Aurora, Colorado, United States of America
    PLoS ONE 6:e28172. 2011
  5. pmc Effect of abatacept on immunogenicity of vaccines in individuals with type 1 diabetes
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Anschutz Medical Campus, Mail Stop 8604, 12700 East 19th Avenue, Aurora, CO 80045, United States Electronic address
    Vaccine 31:4791-4. 2013
  6. pmc Humoral, mucosal, and cell-mediated immunity against vaccine and nonvaccine genotypes after administration of quadrivalent human papillomavirus vaccine to HIV-infected children
    Adriana Weinberg
    University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    J Infect Dis 206:1309-18. 2012
  7. pmc Immune correlates of herpes zoster in HIV-infected children and youth
    Adriana Weinberg
    University of Colorado Denver, Aurora, Colorado, USA
    J Virol 86:2878-81. 2012
  8. doi VZV T cell-mediated immunity
    Adriana Weinberg
    University of Colorado Denver, Aurora, CO 80045, USA
    Curr Top Microbiol Immunol 342:341-57. 2010
  9. doi Incidence and morbidity of human metapneumovirus and other community-acquired respiratory viruses in lung transplant recipients
    A Weinberg
    Department of Pediatrics, University of Colorado Denver, Aurora, CO 80045, USA
    Transpl Infect Dis 12:330-5. 2010
  10. pmc Influence of age and nature of primary infection on varicella-zoster virus-specific cell-mediated immune responses
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Denver, Aurora, Colorado, USA
    J Infect Dis 201:1024-30. 2010

Detail Information

Publications72

  1. pmc Virologic and immunologic correlates with the magnitude of antibody responses to the hepatitis A vaccine in HIV-infected children on highly active antiretroviral treatment
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Denver, Aurora, CO 80045, USA
    J Acquir Immune Defic Syndr 52:17-24. 2009
    ..We sought to identify the immunologic and virologic factors associated with a robust response to hepatitis A virus (HAV) vaccine in children on highly active antiretroviral treatment...
  2. pmc Kinetics and determining factors of the virologic response to antiretrovirals during pregnancy
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    Infect Dis Obstet Gynecol 2009:621780. 2009
    ..In conclusion, the virologic responses of pregnant and nonpregnant adults share similar characteristics...
  3. pmc Pandemic influenza A H1N1 2009 infection versus vaccination: a cohort study comparing immune responses in pregnancy
    Barbra M Fisher
    Department of Obstetrics and Gynecology, Section of Maternal Fetal Medicine, University of Colorado School of Medicine, Aurora, Colorado, United States of America
    PLoS ONE 7:e33048. 2012
    ..We sought to compare the immune response of pregnant women to H1N1 infection versus vaccination and to determine the extent of passive immunity conferred to the newborn...
  4. pmc Dynamics of regulatory T-cells during pregnancy: effect of HIV infection and correlations with other immune parameters
    Kelly Richardson
    Department of Pediatrics, University of Colorado Denver, Aurora, Colorado, United States of America
    PLoS ONE 6:e28172. 2011
    ..We studied Treg subpopulations in HIV-infected and uninfected women during pregnancy and their relationship with inflammation, activation and cell-mediated immunity (CMI)...
  5. pmc Effect of abatacept on immunogenicity of vaccines in individuals with type 1 diabetes
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Anschutz Medical Campus, Mail Stop 8604, 12700 East 19th Avenue, Aurora, CO 80045, United States Electronic address
    Vaccine 31:4791-4. 2013
    ..We conclude that abatacept moderately decreases the magnitude of antibody responses to recall vaccination. Further studies are needed to assess its effect on primary immunization. ..
  6. pmc Humoral, mucosal, and cell-mediated immunity against vaccine and nonvaccine genotypes after administration of quadrivalent human papillomavirus vaccine to HIV-infected children
    Adriana Weinberg
    University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    J Infect Dis 206:1309-18. 2012
    ..To characterize the immunogenicity of a quadrivalent human papillomavirus vaccine (QHPV) in human immunodeficiency virus (HIV)-infected children, we studied their immune responses to 3 or 4 doses...
  7. pmc Immune correlates of herpes zoster in HIV-infected children and youth
    Adriana Weinberg
    University of Colorado Denver, Aurora, Colorado, USA
    J Virol 86:2878-81. 2012
    ..In contrast, high nonspecific regulatory and activated T cells were associated with an increased risk of HZ...
  8. doi VZV T cell-mediated immunity
    Adriana Weinberg
    University of Colorado Denver, Aurora, CO 80045, USA
    Curr Top Microbiol Immunol 342:341-57. 2010
    ..Similarly, the magnitude of these responses early after the onset of herpes zoster correlates with the extent of zoster-associated pain. These essential immune responses are boosted by the VZV vaccine developed to prevent herpes zoster...
  9. doi Incidence and morbidity of human metapneumovirus and other community-acquired respiratory viruses in lung transplant recipients
    A Weinberg
    Department of Pediatrics, University of Colorado Denver, Aurora, CO 80045, USA
    Transpl Infect Dis 12:330-5. 2010
    ..No deaths occurred during this study. In conclusion, HMPV was associated with 6% of the RTIs in lung transplant recipients and its morbidity was similar to the average moribidity of CARVs...
  10. pmc Influence of age and nature of primary infection on varicella-zoster virus-specific cell-mediated immune responses
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Denver, Aurora, Colorado, USA
    J Infect Dis 201:1024-30. 2010
    ..We studied the relationship between VZV cell-mediated immunity and age after varicella or VZV vaccination in healthy and human immunodeficiency virus (HIV)-infected individuals...
  11. ncbi Safety and immunogenicity of a live attenuated varicella vaccine in VZV-seropositive HIV-infected adults
    Adriana Weinberg
    University of Colorado Denver School of Medicine, Aurora, CO, USA
    Hum Vaccin 6:318-21. 2010
    ..We evaluated the safety and immunogenicity of a live attenuated varicella-zoster virus (VZV) vaccine as a candidate for protecting HIV-infected adults against herpes-zoster...
  12. pmc T cell responses of HIV-infected children after administration of inactivated or live attenuated influenza vaccines
    Adriana Weinberg
    University of Colorado Denver, Aurora, 80045, USA
    AIDS Res Hum Retroviruses 26:51-9. 2010
    ..LAIV administration suppressed ELISPOT responses less. The clinical significance of these findings deserves further study...
  13. pmc Optimization of storage and shipment of cryopreserved peripheral blood mononuclear cells from HIV-infected and uninfected individuals for ELISPOT assays
    Adriana Weinberg
    Infectious Diseases, University of Colorado Denver, Aurora, CO, United States
    J Immunol Methods 363:42-50. 2010
    ..However, ELISPOT values significantly decreased with the duration of storage at -70°C both in HIV-infected and uninfected donors. ELISPOT results also decreased with PBMC viability <70%...
  14. doi Effect of menstrual cycle variation in female sex hormones on cellular immunity and regulation
    Adriana Weinberg
    Department of Pediatrics, The University of Colorado Denver, School of Medicine, Aurora, CO 80045, USA
    J Reprod Immunol 89:70-7. 2011
    ..In conclusion, the increase in progesterone levels during the menstrual cycle was associated with higher Treg frequencies and lower CMI...
  15. pmc Safety and tolerability of antiretrovirals during pregnancy
    Adriana Weinberg
    School of Medicine University of Colorado Denver, Research Complex, Aurora, CO 80045, USA
    Infect Dis Obstet Gynecol 2011:867674. 2011
    ..Our data emphasize the need to revise the treatment recommendations for pregnant women to include safer and better-tolerated drugs...
  16. ncbi Varicella-zoster virus-specific immune responses to herpes zoster in elderly participants in a trial of a clinically effective zoster vaccine
    Adriana Weinberg
    University of Colorado Denver, Denver, CO, USA
    J Infect Dis 200:1068-77. 2009
    ....
  17. doi Resistance to antiretrovirals in HIV-infected pregnant women
    Adriana Weinberg
    University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    J Clin Virol 45:39-42. 2009
    ..Antiretrovirals suppress HIV replication and prevent mother-to-child-transmission of HIV (PMTCT). Resistance to antiretrovirals may reduce the efficacy of PMTCT and/or complicate treatment of maternal or infant infection...
  18. pmc Anti-influenza serum and mucosal antibody responses after administration of live attenuated or inactivated influenza vaccines to HIV-infected children
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Denver, Aurora, CO, USA
    J Acquir Immune Defic Syndr 55:189-96. 2010
    ..Live-attenuated influenza vaccine (LAIV) prevents more cases of influenza in immune-competent children than the trivalent inactivated vaccine (TIV). We compared the antibody responses to LAIV or TIV in HIV-infected children...
  19. pmc Continuous improvement in the immune system of HIV-infected children on prolonged antiretroviral therapy
    Adriana Weinberg
    University of Colorado Denver School of Medicine, Denver, Colorado, USA
    AIDS 22:2267-77. 2008
    ..The goal of HAART is to promote reconstitution of CD4+ T cells and other immune responses. We evaluated the extent and the kinetics of immune reconstitution in HIV-infected children over 144 weeks of successful HAART...
  20. ncbi Cytomegalovirus-specific cell-mediated immunity in HIV-infected children on HAART
    Adriana Weinberg
    Section of Pediatric Infectious Diseases, University of Colorado School of Medicine, Denver, Colorado 80262, USA
    AIDS Res Hum Retroviruses 22:283-8. 2006
    ....
  21. pmc Reactivation of latent viruses in individuals receiving rituximab for new onset type 1 diabetes
    Jing Lu Kroll
    Divison of Adult Infectious Diseases, University of Colorado School of Medicine, Aurora, USA
    J Clin Virol 57:115-9. 2013
    ..However, like with any immunosuppressive therapy, there is a concern of opportunistic viral reactivations with the use of rituximab, including herpes and polyomaviruses...
  22. ncbi Regulatory T cells generated during cytomegalovirus in vitro stimulation of mononuclear cells from HIV-infected individuals on HAART correlate with decreased lymphocyte proliferation
    Renee D Jesser
    Department of Pediatric Infectious Diseases, University of Colorado Health Sciences Center, 4200 E 9th Avenue, UCHSC School of Medicine, Denver, CO 80262, USA
    Virology 352:408-17. 2006
    ..These data indicate that FoxP3- and TGFbeta1-expressing regulatory T cells contribute to decreased immunity in HAART recipients...
  23. doi Kinetics of viral shedding and immune responses in adults following administration of cold-adapted influenza vaccine
    Laura L Hammitt
    Section of Infectious Diseases, Department of Pediatrics, University of Colorado Denver, Denver, CO, United States
    Vaccine 27:7359-66. 2009
    ..PBMCs from subjects receiving CAIV showed a higher proportion of functional, tissue-tropic T-cells (CD4+CD69+CD18+MIP1alpha+) specific for homotypic and heterosubtypic strains of influenza by flow cytometry...
  24. ncbi Development of resistance to acyclovir during chronic infection with the Oka vaccine strain of varicella-zoster virus, in an immunosuppressed child
    Myron J Levin
    Section of Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Infect Dis 188:954-9. 2003
    ..This is the first report of Oka-strain varicella virus causing severe disease after reactivation and of resistance to acyclovir during an infection caused by this virus...
  25. pmc Safety and immunogenicity of a quadrivalent human papillomavirus (types 6, 11, 16, and 18) vaccine in HIV-infected children 7 to 12 years old
    Myron J Levin
    Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO, USA
    J Acquir Immune Defic Syndr 55:197-204. 2010
    ..Quadrivalent human papillomavirus vaccine (QHPV) is > 95% effective in preventing infection with vaccine-type human papillomavirus. The safety and immunogenicity of QHPV are unknown in HIV-infected children...
  26. pmc A phase I-II study of live attenuated varicella-zoster virus vaccine to boost immunity in human immunodeficiency virus-infected children with previous varicella
    Anne A Gershon
    Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Pediatr Infect Dis J 28:653-5. 2009
    ..There were no serious adverse events. Two years after vaccination 82% of subjects remained VZV-antibody positive and 60% had VZV-specific cell-mediated immunity. No child developed herpes zoster...
  27. ncbi Phenotypic and functional characterization of ex vivo T cell responses to the live attenuated herpes zoster vaccine
    Julie Patterson-Bartlett
    Department of Pediatrics of the University of Colorado School of Medicine, Denver, CO 80262, USA
    Vaccine 25:7087-93. 2007
    ..The vaccine significantly increased VZV-specific Th1, memory, early effector, and cutaneous homing receptor-bearing T cells...
  28. ncbi Administration of live varicella vaccine to HIV-infected children with current or past significant depression of CD4(+) T cells
    Myron J Levin
    University of Colorado School of Medicine, Denver, Denver, CO 80262, USA
    J Infect Dis 194:247-55. 2006
    ..The licensed, live attenuated varicella vaccine is safe and immunogenic in HIV-infected children with minimal symptoms and good preservation of CD4(+) T cells (Centers for Disease Control and Prevention immunologic category 1)...
  29. pmc Regulatory function of cytomegalovirus-specific CD4+CD27-CD28- T cells
    Adriana Tovar-Salazar
    University of Colorado Denver School of Medicine, Aurora, CO, USA
    Virology 398:158-67. 2010
    ..The CMV-CD4+CD27-CD28- TR may contribute to the downregulation of CMV-specific and nonspecific immune responses of CMV-infected individuals...
  30. ncbi Risk of transmission of herpesviruses through cord blood transplantation
    Adriana Weinberg
    University of Colorado School of Medicine, Denver, Colorado, USA
    Biol Blood Marrow Transplant 11:35-8. 2005
    ..Our data show that screening prospective CB donors with anti-CMV immunoglobulin M practically eliminates the risk of CB CMV transmission, but HHV-6 warrants CB testing by polymerase chain reaction...
  31. ncbi Cytomegalovirus-specific immunity and protection against viremia and disease in HIV-infected patients in the era of highly active antiretroviral therapy
    Adriana Weinberg
    University of Colorado School of Medicine, Denver, 80262, USA
    J Infect Dis 193:488-93. 2006
    ..CMV viremia did not appear to boost CMV-specific immunity. ELISPOT assays may be used to identify HIV-infected patients who might benefit from anti-CMV prophylactic interventions...
  32. ncbi Cytomegalovirus-specific IFN-gamma production is associated with protection against cytomegalovirus reactivation in HIV-infected patients on highly active antiretroviral therapy
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver 80262, USA
    AIDS 17:2445-50. 2003
    ..To identify the predictors of cytomegalovirus reactivation in AIDS patients on highly active antiretroviral therapy (HAART)...
  33. pmc Optimization and limitations of use of cryopreserved peripheral blood mononuclear cells for functional and phenotypic T-cell characterization
    Adriana Weinberg
    University of Colorado Denver School of Medicine, Denver, CO, USA
    Clin Vaccine Immunol 16:1176-86. 2009
    ....
  34. pmc Safety and immunogenicity of 2009 pH1N1 vaccination in HIV-infected pregnant women
    Mark J Abzug
    Department of Pediatrics, Infectious Diseases, University of Colorado School of Medicine and Children s Hospital Colorado, Aurora, CO, USA
    Clin Infect Dis 56:1488-97. 2013
    ..The safety and immunogenicity of pH1N1 vaccination in HIV-infected pregnant women are unknown...
  35. pmc Shedding of live vaccine virus, comparative safety, and influenza-specific antibody responses after administration of live attenuated and inactivated trivalent influenza vaccines to HIV-infected children
    Myron J Levin
    University of Colorado School of Medicine, Aurora, CO 80045 0508, United States
    Vaccine 26:4210-7. 2008
    ..LAIV should be further evaluated for a role in immunizing HIV-infected children...
  36. pmc Distinctive in vitro effects of T-cell growth cytokines on cytomegalovirus-stimulated T-cell responses of HIV-infected HAART recipients
    Julie Patterson
    Department of Pediatrics, University of Colorado School of Medicine, Denver, CO 80262, USA
    Virology 378:48-57. 2008
    ..Overall, compared to other gamma-chain cytokines, IL-15 had the most favorable profile for boosting antiviral cell-mediated immunity...
  37. ncbi Varicella-Zoster virus-specific cell-mediated immunity in HIV-infected children receiving highly active antiretroviral therapy
    Adriana Weinberg
    Section of Pediatric Infectious Diseases, and Department of Medicine, University of Colorado School of Medicine, Denver, Colorado, USA
    J Infect Dis 190:267-70. 2004
    ..After developing HZ, only the 2 HAART-compliant patients developed VZV-CMI. Thus, VZV-specific immune reconstitution in HIV infection may require antigenic reexposure, in addition to control of HIV replication...
  38. pmc How evolution of mutations conferring drug resistance affects viral dynamics and clinical outcomes of cytomegalovirus-infected hematopoietic cell transplant recipients
    Kathryn L Springer
    Division of Infectious Diseases, University of Colorado Health Sciences Center, 4200 E 9th Ave, C 227, Denver, CO 80220, USA
    J Clin Microbiol 43:208-13. 2005
    ..Novel antivirals or combination therapy may be required for the treatment of drug-resistant CMV in HCT recipients and perhaps in other severely immunocompromised patients...
  39. ncbi History of chickenpox and shingles and prevalence of antibodies to varicella-zoster virus and three other herpesviruses among adults with glioma and controls
    Margaret Wrensch
    Department of Neurological Surgery, School of Medicine, University of California, San Francisco, CA 94102, USA
    Am J Epidemiol 161:929-38. 2005
    ..Cohort studies may help to clarify the nature of the association between immunity to and/or clinical manifestations of varicella-zoster virus and glioblastoma...
  40. ncbi Factors that affect in vitro measurement of the susceptibility of herpes simplex virus to nucleoside analogues
    Adriana Weinberg
    Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Denver, CO, United States
    J Clin Virol 38:139-45. 2007
    ..To identify factors that contribute to variability of HSV antiviral susceptibility breakpoints...
  41. ncbi Dual infections of the central nervous system with Epstein-Barr virus
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Medical School, Denver, CO 80262, USA
    J Infect Dis 191:234-7. 2005
    ..EBV lytic-cycle mRNA was detected in the cerebrospinal fluid of 5 of 6 tested samples, indicating EBV replication in the CNS during coinfection...
  42. pmc Immunity to human immunodeficiency virus (HIV) in children with chronic HIV infection receiving highly active antiretroviral therapy
    Adriana Weinberg
    Department of Pediatrics, University of Colorado School of Medicine, Denver, Colorado, USA
    Clin Diagn Lab Immunol 10:821-5. 2003
    ..We concluded that the association between HIV CMI and CMV CMI indicates that the same factors govern responsiveness to either antigen...
  43. ncbi Antibody responses to hepatitis A virus vaccine in HIV-infected children with evidence of immunologic reconstitution while receiving highly active antiretroviral therapy
    Adriana Weinberg
    Department of Pediatrics and Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA
    J Infect Dis 193:302-11. 2006
    ..We investigated the safety and immunogenicity of 2 doses of hepatitis A virus (HAV) vaccine followed by a booster dose in HIV-infected children receiving stable highly active antiretroviral therapy...
  44. ncbi Lopinavir exposure with an increased dose during pregnancy
    Mark Mirochnick
    Department of Pediatrics, Boston University School of Medicine, and Infectious Disease Division, Children s Hospital Boston, Boston, MA 02118, USA
    J Acquir Immune Defic Syndr 49:485-91. 2008
    ..The goal of this study was to determine LPV exposure during the third trimester of pregnancy and 2 weeks postpartum with a higher LPV/RTV dose...
  45. doi Varicella-zoster virus-specific immune responses in elderly recipients of a herpes zoster vaccine
    M J Levin
    University of Colorado Health Sciences Center, Denver, Colorado, USA
    J Infect Dis 197:825-35. 2008
    ..The trial included an immunology substudy to determine the relationship of VZV-specific immune responses to vaccination and clinical outcome...
  46. ncbi Evaluation of R-Mix shell vials for the diagnosis of viral respiratory tract infections
    Adriana Weinberg
    University of Colorado Health Sciences Center, Campus Box C227, 4200 E 9th Avenue, Denver, CO 80262, USA
    J Clin Virol 30:100-5. 2004
    ..In contrast, R-Mix harvested at 24h did not seem a very useful diagnostic tool. The utility of R-Mix harvested at 120 h, which accelerated the diagnosis of 16% of positive specimens in study phase 2, needs further investigation...
  47. ncbi Excess apoptosis of mononuclear cells contributes to the depressed cytomegalovirus-specific immunity in HIV-infected patients on HAART
    Adriana Weinberg
    Department of Pediatrics of the University of Colorado Health Sciences Center, Denver, CO 80220, USA
    Virology 330:313-21. 2004
    ..This effect was not observed in uninfected controls, further indicating that the down regulatory effect of apoptosis on cell-mediated immunity (CMI) was specifically associated with the HIV-infected status...
  48. doi Reduced immunogenicity of influenza vaccines in HIV-infected compared with uninfected pregnant women is associated with regulatory T cells
    Kelly Richardson
    Department of Pediatrics, University of Colorado Denver, Aurora, USA
    AIDS 25:595-602. 2011
    ..To evaluate the immunogenicity of influenza vaccines in HIV-infected pregnant women and the factors that may determine this response...
  49. ncbi Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis
    Adriana Weinberg
    University of Colorado Health Sciences Center, Denver, Colorado, USA
    J Infect Dis 187:777-84. 2003
    ..016). The incidence of foscarnet resistance after 6, 9, and 12 months of therapy was 13%, 24%, and 37%, respectively...
  50. doi Effect of nucleoside and nucleotide analog reverse transcriptase inhibitors on cell-mediated immune functions
    Laura Enomoto
    University of Colorado Denver, Aurora, USA
    AIDS Res Hum Retroviruses 27:47-55. 2011
    ..In conclusion, AZT had the most pronounced inhibitory effect on CMI. Further studies are warranted to determine the clinical significance of this observation...
  51. pmc Human herpesviruses 6 and 7 and central nervous system infection in children
    Asad Ansari
    University of Colorado School of Medicine, Denver, Colorado 90262, USA
    Emerg Infect Dis 10:1450-4. 2004
    ..HHV-6 was likely pathogenic in two patients with meningitis who lacked evidence of another microbiologic cause. HHV-6 and HHV-7 are uncommon causes of CNS infection in children. HHV-6 may occasionally cause meningitis in young infants...
  52. ncbi The value of polymerase chain reaction for the diagnosis of viral respiratory tract infections in lung transplant recipients
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Clin Virol 25:171-5. 2002
    ..Respiratory viruses cause severe infections in lung transplant recipients, which require rapid and accurate diagnosis for appropriate management...
  53. ncbi Ex vivo effect of estrogen and progesterone compared with dexamethasone on cell-mediated immunity of HIV-infected and uninfected subjects
    Laura M Enomoto
    University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Acquir Immune Defic Syndr 45:137-43. 2007
    ..Overall, HCT concentrations of estrogen and progesterone downregulated ex vivo VZV CMI of HIV-infected and uninfected subjects...
  54. doi Human metapneumovirus
    Jing Lu Kroll
    Department of Medicine, Division of Infectious Diseases, University of Colorado Denver, Aurora, Colorado 80045, USA
    Semin Respir Crit Care Med 32:447-53. 2011
    ..Monoclonal antibodies have activity in murine models but are not available in humans. Several vaccines are promising in animal models, but their safety and efficacy have not yet been evaluated in humans...
  55. ncbi Antimicrobial-specific cell-mediated immune reconstitution in children with advanced human immunodeficiency virus infection receiving highly active antiretroviral therapy
    Adriana Weinberg
    University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Clin Infect Dis 39:107-14. 2004
    ..Additional factors for immune reconstitution were low HIV load, high CD4+ cell percentages, and low levels of activated CD8+ cells...
  56. ncbi Regulatory T cells and the risk of CMV end-organ disease in patients with AIDS
    Adriana Weinberg
    Department of Pediatric Medicine and Pathology, School of Medicine, University of Colorado Denver, Aurora, CO Department of Biostatistics, Harvard School of Public Health, Boston, MA Division of Infectious Diseases, School of Medicine, University of San Diego, San Diego, CA Division of Allergy and Infectious Diseases, School of Medicine, Harborview Medical Center and the University of Washington School of Medicine, Seattle, WA Department of Infectious Diseases, School of Medicine, University of Stanford, Stanford, CA Department of Medicine, Division of Infectious Diseases, Weill Medical College of Cornell University, New York, NY Division of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC Department of Medicine, St Luke s Roosevelt Medical Center and Columbia University College of Physicians and Surgeons, New York, NY Servicio de Medicina Interna, Hospital Asepeyo Coslada, Madrid, Spain and Department of Medicine, University of California, San Francisco, San Francisco, CA
    J Acquir Immune Defic Syndr 66:25-32. 2014
    ..We investigated the contribution of Treg and Teff toward CMV-EOD in HIV-infected individuals independently of CD4 cell numbers and HIV load and controlling for CMV reactivations...
  57. ncbi Cytomegalovirus infection in the era of HAART: fewer reactivations and more immunity
    Kathryn L Springer
    Departments of Medicine and Pediatrics, University of Colorado School of Medicine, Denver, Colorado, USA
    J Antimicrob Chemother 54:582-6. 2004
    ....
  58. pmc Evaluation of three immunoassay kits for rapid detection of influenza virus A and B
    Adriana Weinberg
    University of Colorado Health Sciences Center, 4200 E 9th Ave, Campus Box C227, Denver, CO 80220, USA
    Clin Diagn Lab Immunol 12:367-70. 2005
    ..Overall, NOW provided the most accurate diagnoses and had user-friendly technical characteristics. However, the low overall sensitivity of the RIIAs indicates that these can be used as screening tools only...
  59. doi Relationship of reconstituted adaptive and innate cytomegalovirus (CMV)-specific immune responses with CMV viremia in hematopoietic stem cell transplant recipients
    Michelle A Barron
    Division of Infectious Diseases, School of Public Health, University of Colorado Denver, Aurora, Colorado 80045, USA
    Clin Infect Dis 49:1777-83. 2009
    ..Cytomegalovirus (CMV) is a major cause of morbidity in transplant recipients. An immunologic predictor of protection against CMV reactivation or disease is highly desirable...
  60. ncbi Sensitivity of diagnostic tests for influenza varies with the circulating strains
    Adriana Weinberg
    Clinical Virology Laboratory, University of Colorado Hospital, 4200 East Ninth Avenue, Denver, CO 80262, USA
    J Clin Virol 33:172-5. 2005
    ..Effective strategies to combat the spread of influenza viruses rely on accurate diagnosis of the infection, which is greatly affected by the sensitivity of the assays used...
  61. pmc Quality assurance program for peripheral blood mononuclear cell cryopreservation
    Adriana Weinberg
    University of Colorado Health Sciences Center, Denver, Colorado, USA
    Clin Vaccine Immunol 14:1242-4. 2007
    ..S. laboratory for analysis. Cell viability and recovery significantly increased over time. A wet-laboratory training session conducted at the central laboratory significantly improved the quality of the cryopreserved PBMC...
  62. ncbi Quantitative CSF PCR in Epstein-Barr virus infections of the central nervous system
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Health Sciences Center, Campus Box C227, Denver, CO 80263, USA
    Ann Neurol 52:543-8. 2002
    ..These studies demonstrate the utility of quantitative CSF PCR and establish the presence of lytic cycle EBV mRNA in CSF of patients with EBV-associated neurological disease...
  63. doi Successful treatment of acyclovir-resistant herpes simplex virus type 2 proctitis with leflunomide in an HIV-infected man
    Andres F Henao-Martinez
    University of Colorado Denver, Aurora, CO 80045, USA
    J Clin Virol 54:276-8. 2012
    ..Leflunomide has been shown to possess antiviral activity against several viruses. Herein we describe a case of acyclovir resistant HSV-2 proctitis in an HIV patient successfully treated with leflunomide without significant side effects...
  64. doi Cytotoxicity of glioblastoma cells mediated ex vivo by varicella-zoster virus-specific T cells
    Jennifer Canniff
    Department of Pediatrics, University Colorado Denver School of Medicine, Denver, CO, USA
    J Neurovirol 17:448-54. 2011
    ..The protective effect of prior VZV infection against the incidence of glioma may be mediated by CTL that recognizes epitopes shared by VZV and glioma cells...
  65. pmc Molecular methods for cytomegalovirus surveillance in bone marrow transplant recipients
    Adriana Weinberg
    Departments of Pediatrics, University of Colorado, Denver, Colorado 80262, USA
    J Clin Microbiol 40:4203-6. 2002
    ..These data suggest that WB or PBLs might be the preferred sample for use for surveillance for CMV in immunocompromised patients...
  66. ncbi Susceptibility of herpes simplex virus isolates to nucleoside analogues and the proportion of nucleoside-resistant variants after repeated topical application of penciclovir to recurrent herpes labialis
    Young Kyoo Shin
    Section of Pediatric Infectious Diseases, School of Medicine, University of Colorado, Denver, Colorado, USA
    J Infect Dis 187:1241-5. 2003
    ..We conclude that antiviral-resistant variants, which are readily detected in HSV isolates from peripheral lesions, do not accumulate in the sensory ganglia of immunocompetent patients receiving multiple courses of nucleoside analogues...
  67. doi Lytic and latent EBV gene expression in transplant recipients with and without post-transplant lymphoproliferative disorder
    Jing Kroll
    Department of Internal Medicine, University of Colorado Denver, CO 80045, USA
    J Clin Virol 52:231-5. 2011
    ..To devise prophylactic measures, we need predictors of PTLD and a better understanding of the physiopathogenesis of the disease...
  68. doi Introduction to the special issue dedicated to the 11th International CMV and Beta Herpesvirus Workshop
    Adriana Weinberg
    Department of Infectious Disease, University of Colorado, 4200 E 9th Avenue, Mail Stop C227, Denver, CO 80262, United States
    J Clin Virol 41:173. 2008
  69. ncbi Relationship of Kaposi sarcoma (KS)-associated herpesvirus viremia and KS disease in Zimbabwe
    Thomas B Campbell
    Division of Infectious Diseases, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Clin Infect Dis 36:1144-51. 2003
    ..These findings provide evidence that KSHV viremia is common in advanced AIDS-KS in Zimbabwe and suggest a relationship between KSHV lytic replication and untreated HIV-1 infection...
  70. ncbi Long-term safety and efficacy of a once-daily regimen of emtricitabine, didanosine, and efavirenz in HIV-infected, therapy-naive children and adolescents: Pediatric AIDS Clinical Trials Group Protocol P1021
    Ross E McKinney
    Department of Pediatrics, Duke University Medical Center, Box 3461, Durham, NC 27710, USA
    Pediatrics 120:e416-23. 2007
    ..Compliance with complex antiretroviral therapy regimens is a problem for HIV-1-infected children and their families. Simple, safe, and effective regimens are important for long-term therapeutic success...
  71. ncbi Use of PCR for the diagnosis of herpesvirus infections of the central nervous system
    Roberta L Debiasi
    Department of Pediatrics, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, 80262, Denver, CO 80262, USA
    J Clin Virol 25:S5-11. 2002
    ..This review summarizes the role of CSF PCR in the diagnosis and therapeutic management of herpesvirus infections of the nervous system, particularly those caused by HSV and VZV...
  72. ncbi The role of immune reconstitution in cytomegalovirus infection
    Adriana Weinberg
    Departments of Pediatrics and Medicine, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Campus Box C227, Denver, CO 80262, USA
    BioDrugs 16:89-95. 2002
    ..In addition, there is a continuous effort to develop CMV-specific immune-based therapies including vaccines and immune modulators such as cytokines, which may be of supplemental benefit in the control of CMV disease...