Douglas B Weibel

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Pumping fluids in microfluidic systems using the elastic deformation of poly(dimethylsiloxane)
    Douglas B Weibel
    Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, WI 53706, USA
    Lab Chip 7:1832-6. 2007
  2. ncbi request reprint Microfabrication meets microbiology
    Douglas B Weibel
    Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, Wisconsin 53706, USA
    Nat Rev Microbiol 5:209-18. 2007
  3. ncbi request reprint Applications of microfluidics in chemical biology
    Douglas B Weibel
    Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, WI 53706, USA
    Curr Opin Chem Biol 10:584-91. 2006
  4. pmc MinD and MinE interact with anionic phospholipids and regulate division plane formation in Escherichia coli
    Lars D Renner
    Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Biol Chem 287:38835-44. 2012
  5. pmc Rapid identification of ESKAPE bacterial strains using an autonomous microfluidic device
    Jack Y Ho
    Department of Biomedical Engineering, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 7:e41245. 2012
  6. pmc Measuring the stiffness of bacterial cells from growth rates in hydrogels of tunable elasticity
    Hannah H Tuson
    Department of Biochemistry, University of Wisconsin Madison, Madison, WI 53706, USA
    Mol Microbiol 84:874-91. 2012
  7. pmc Quorum sensing between Pseudomonas aeruginosa biofilms accelerates cell growth
    Shane T Flickinger
    Department of Biochemistry, University of Wisconsin Madison, Madison, Wisconsin 53706, United States
    J Am Chem Soc 133:5966-75. 2011
  8. pmc Encapsulating bacteria in agarose microparticles using microfluidics for high-throughput cell analysis and isolation
    Ye Jin Eun
    Department of Biochemistry, University of Wisconsin Madison, 53706, United States
    ACS Chem Biol 6:260-6. 2011
  9. pmc Flagellum density regulates Proteus mirabilis swarmer cell motility in viscous environments
    Hannah H Tuson
    Department of Biochemistry, University of Wisconsin Madison, Madison, WI, USA
    J Bacteriol 195:368-77. 2013
  10. pmc Divin: a small molecule inhibitor of bacterial divisome assembly
    Ye Jin Eun
    Department of Biochemistry, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Am Chem Soc 135:9768-76. 2013

Collaborators

  • G M Whitesides
  • Martin Thanbichler
  • Kerwyn Casey Huang
  • Shoji Takeuchi
  • P Garstecki
  • Ye Jin Eun
  • Hannah H Tuson
  • Lars D Renner
  • Matthew F Copeland
  • Nate J Cira
  • Jack Y Ho
  • Marie H Foss
  • Shane T Flickinger
  • Daniela Kiekebusch
  • Abishek Muralimohan
  • Adam C Siegel
  • Molly M Stevens
  • Shengqing Xu
  • Maoquan Zhou
  • Zhou Zhong
  • Taylor A Wahlig
  • Rishi R Trivedi
  • Sonia Carey
  • Ryan Sacotte
  • Somenath Bakshi
  • Susan Schlimpert
  • Max Salick
  • Carolina Tropini
  • Wendy C Crone
  • Josue Baeza
  • Ajay Gopinathan
  • Daniel A Pauw
  • William M Westler
  • George K Auer
  • Megan E Dueck
  • John A Crooks
  • Mariko Hasebe
  • Andrew S Utada
  • Eric M Downes
  • Andrew T Braasch
  • Basudeb Bhattacharyya
  • Sergey S Shevkoplyas
  • Andres W Martinez
  • Derek A Bruzewicz
  • Howard A Stone
  • Minseok Seo
  • Patrick Lewis
  • Daniel G Anderson
  • Eugenia Kumacheva
  • Michael Mayer
  • Irina Gitlin
  • Robert Langer
  • Zhihong Nie

Detail Information

Publications24

  1. ncbi request reprint Pumping fluids in microfluidic systems using the elastic deformation of poly(dimethylsiloxane)
    Douglas B Weibel
    Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, WI 53706, USA
    Lab Chip 7:1832-6. 2007
    ....
  2. ncbi request reprint Microfabrication meets microbiology
    Douglas B Weibel
    Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, Wisconsin 53706, USA
    Nat Rev Microbiol 5:209-18. 2007
    ....
  3. ncbi request reprint Applications of microfluidics in chemical biology
    Douglas B Weibel
    Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, WI 53706, USA
    Curr Opin Chem Biol 10:584-91. 2006
    ..The review concludes with an assessment of future directions and opportunities of microfluidics in chemical biology...
  4. pmc MinD and MinE interact with anionic phospholipids and regulate division plane formation in Escherichia coli
    Lars D Renner
    Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Biol Chem 287:38835-44. 2012
    ....
  5. pmc Rapid identification of ESKAPE bacterial strains using an autonomous microfluidic device
    Jack Y Ho
    Department of Biomedical Engineering, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 7:e41245. 2012
    ....
  6. pmc Measuring the stiffness of bacterial cells from growth rates in hydrogels of tunable elasticity
    Hannah H Tuson
    Department of Biochemistry, University of Wisconsin Madison, Madison, WI 53706, USA
    Mol Microbiol 84:874-91. 2012
    ..Our technique therefore enables the rapid determination of how changes in genotype and biochemistry affect the mechanical properties of the bacterial envelope...
  7. pmc Quorum sensing between Pseudomonas aeruginosa biofilms accelerates cell growth
    Shane T Flickinger
    Department of Biochemistry, University of Wisconsin Madison, Madison, Wisconsin 53706, United States
    J Am Chem Soc 133:5966-75. 2011
    ..The results suggest that the secretion of HSLs from a biofilm enhances the growth of neighboring cells in contact with surfaces into communities and may influence their composition, organization, and diversity...
  8. pmc Encapsulating bacteria in agarose microparticles using microfluidics for high-throughput cell analysis and isolation
    Ye Jin Eun
    Department of Biochemistry, University of Wisconsin Madison, 53706, United States
    ACS Chem Biol 6:260-6. 2011
    ..We envision that this technique will have an important impact on research in chemical biology, natural products chemistry, and the discovery and characterization of biologically active secondary metabolites...
  9. pmc Flagellum density regulates Proteus mirabilis swarmer cell motility in viscous environments
    Hannah H Tuson
    Department of Biochemistry, University of Wisconsin Madison, Madison, WI, USA
    J Bacteriol 195:368-77. 2013
    ..mirabilis flagellum density and cell motility in viscous environments that may be relevant to its adaptation during the infection of mammalian urinary tracts and movement in contact with indwelling catheters...
  10. pmc Divin: a small molecule inhibitor of bacterial divisome assembly
    Ye Jin Eun
    Department of Biochemistry, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Am Chem Soc 135:9768-76. 2013
    ..These characteristics make divin a useful probe for studying bacterial cell division and a starting point for the development of new classes of therapeutic agents...
  11. pmc DCAP: a broad-spectrum antibiotic that targets the cytoplasmic membrane of bacteria
    Ye Jin Eun
    Department of Biochemistry, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Am Chem Soc 134:11322-5. 2012
    ..DCAP expands the limited number of compounds in this class of therapeutic small molecules and provides new opportunities for the development of potent broad-spectrum antimicrobial agents...
  12. pmc Polyacrylamide hydrogels as substrates for studying bacteria
    Hannah H Tuson
    Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, WI 53706, USA
    Chem Commun (Camb) 48:1595-7. 2012
    ..Polyacrylamide hydrogels can be used as chemically and physically defined substrates for bacterial cell culture, and enable studies of the influence of surfaces on cell growth and behaviour...
  13. doi request reprint A self-loading microfluidic device for determining the minimum inhibitory concentration of antibiotics
    Nate J Cira
    Department of Biomedical Engineering, University of Wisconsin Madison, Madison, WI 53706, USA
    Lab Chip 12:1052-9. 2012
    ..As the device introduces a novel approach for filling and isolating dead-end microfluidic chambers that does not require valves and actuators, this technology should find applications in other portable assays and devices...
  14. doi request reprint Dissecting microbiological systems using materials science
    Abishek Muralimohan
    Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, WI 53706, USA
    Trends Microbiol 17:100-8. 2009
    ..This review summarizes three classes of materials that span a range of length scales (nano, micro and meso) and describes a variety of fundamental questions in microbiology that can be studied by leveraging their properties...
  15. doi request reprint Chemical-biological studies of subcellular organization in bacteria
    Marie H Foss
    Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706, United States
    Biochemistry 50:7719-34. 2011
    ....
  16. doi request reprint Fabrication of microbial biofilm arrays by geometric control of cell adhesion
    Ye Jin Eun
    Department of Biochemistry, University of Wisconsin Madison, Madison, WI 53706, USA
    Langmuir 25:4643-54. 2009
    ..The method described in this paper makes it possible to study the chemical, physical, and environmental factors that affect biofilm development in a statistically relevant and reproducible format...
  17. pmc Cardiolipin microdomains localize to negatively curved regions of Escherichia coli membranes
    Lars D Renner
    Department of Biochemistry and Biomedical Engineering, University of Wisconsin, Madison, WI 53706, USA
    Proc Natl Acad Sci U S A 108:6264-9. 2011
    ..These studies demonstrate the curvature dependence of CL in membranes and test whether these structures participate in the localization of MinD to regions of negative curvature in cells...
  18. pmc Studying the dynamics of flagella in multicellular communities of Escherichia coli by using biarsenical dyes
    Matthew F Copeland
    Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, WI 53706, USA
    Appl Environ Microbiol 76:1241-50. 2010
    ..This approach opens a window for observing the dynamics of cells in communities that are relevant to ecology, industry, and biomedicine...
  19. ncbi request reprint Cofabrication of electromagnets and microfluidic systems in poly(dimethylsiloxane)
    Adam C Siegel
    Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA
    Angew Chem Int Ed Engl 45:6877-82. 2006
  20. ncbi request reprint Combining microscience and neurobiology
    Douglas B Weibel
    Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA
    Curr Opin Neurobiol 15:560-7. 2005
    ..The major impediment to the development of a field of 'microfabrication and measurement' in neuroscience is the absence of effective collaborative interactions between the communities of fabricators and neurobiologists...
  21. ncbi request reprint Modeling the anodic half-cell of a low-temperature coal fuel cell
    Douglas B Weibel
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA
    Angew Chem Int Ed Engl 44:5682-6. 2005
  22. ncbi request reprint Torque-actuated valves for microfluidics
    Douglas B Weibel
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    Anal Chem 77:4726-33. 2005
    ..They also allow settings between "on" and "off" and can be integrated into portable, disposable microfluidic devices for carrying out sandwich immunoassays...
  23. ncbi request reprint Direct patterning of mammalian cells onto porous tissue engineering substrates using agarose stamps
    Molly M Stevens
    Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Biomaterials 26:7636-41. 2005
    ..This approach may find use in controlling the spatial invasion of scaffolds, promoting the hierarchical organization of cells, and in controlling cell-cell interactions as a step in preservation of phenotypes of cells...
  24. ncbi request reprint Generation of monodisperse particles by using microfluidics: control over size, shape, and composition
    Shengqing Xu
    Department of Chemistry, University of Toronto, 80 Saint George Street, Toronto M5S 3H6, Ontario, Canada
    Angew Chem Int Ed Engl 44:724-8. 2005