Casey Weaver

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint IL-17 family cytokines and the expanding diversity of effector T cell lineages
    Casey T Weaver
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Annu Rev Immunol 25:821-52. 2007
  2. pmc Bioluminescence-based visualization of CD4 T cell dynamics using a T lineage-specific luciferase transgenic model
    Joseph H Chewning
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    BMC Immunol 10:44. 2009
  3. pmc Contrasting roles for all-trans retinoic acid in TGF-beta-mediated induction of Foxp3 and Il10 genes in developing regulatory T cells
    Craig L Maynard
    Department of Pathology, University of Alabama at Birmingham, AL 35294, USA
    J Exp Med 206:343-57. 2009
  4. pmc The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin
    Casey T Weaver
    Department of Pathology, University of Alabama at Birmingham, AL 35294, USA
    Annu Rev Pathol 8:477-512. 2013
  5. ncbi request reprint T-cell subsets: the more the merrier
    Casey T Weaver
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Curr Biol 17:R61-3. 2007
  6. ncbi request reprint Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective
    Casey T Weaver
    Department of Pathology, BBRB 870, University Station, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Nat Rev Immunol 9:883-9. 2009
  7. ncbi request reprint Th17: an effector CD4 T cell lineage with regulatory T cell ties
    Casey T Weaver
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Immunity 24:677-88. 2006
  8. ncbi request reprint Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    Laurie E Harrington
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Nat Immunol 6:1123-32. 2005
  9. ncbi request reprint Transforming growth factor-beta induces development of the T(H)17 lineage
    Paul R Mangan
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294 2170, USA
    Nature 441:231-4. 2006
  10. pmc T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis
    Nuzhat Iqbal
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    J Exp Med 195:71-84. 2002

Collaborators

Detail Information

Publications52

  1. ncbi request reprint IL-17 family cytokines and the expanding diversity of effector T cell lineages
    Casey T Weaver
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Annu Rev Immunol 25:821-52. 2007
    ....
  2. pmc Bioluminescence-based visualization of CD4 T cell dynamics using a T lineage-specific luciferase transgenic model
    Joseph H Chewning
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    BMC Immunol 10:44. 2009
    ..Luciferase bioluminescence has recently been utilized for non-invasive analysis of in vivo biologic processes in real-time...
  3. pmc Contrasting roles for all-trans retinoic acid in TGF-beta-mediated induction of Foxp3 and Il10 genes in developing regulatory T cells
    Craig L Maynard
    Department of Pathology, University of Alabama at Birmingham, AL 35294, USA
    J Exp Med 206:343-57. 2009
    ....
  4. pmc The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin
    Casey T Weaver
    Department of Pathology, University of Alabama at Birmingham, AL 35294, USA
    Annu Rev Pathol 8:477-512. 2013
    ..In this review, we focus on recent advances in the biology of the Th17 pathway and on genome-wide association studies that implicate this immune pathway in human disease involving these tissues...
  5. ncbi request reprint T-cell subsets: the more the merrier
    Casey T Weaver
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Curr Biol 17:R61-3. 2007
    ..This year, IL-17-producing T cells were recognized as a distinct lineage and soon thereafter, the cytokines responsible for their induction were delineated. Now, a transcription factor driving their development has been identified...
  6. ncbi request reprint Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective
    Casey T Weaver
    Department of Pathology, BBRB 870, University Station, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Nat Rev Immunol 9:883-9. 2009
    ....
  7. ncbi request reprint Th17: an effector CD4 T cell lineage with regulatory T cell ties
    Casey T Weaver
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Immunity 24:677-88. 2006
    ....
  8. ncbi request reprint Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    Laurie E Harrington
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Nat Immunol 6:1123-32. 2005
    ..These findings provide a basis for understanding how inhibition of IFN-gamma signaling enhances development of pathogenic T(H)-17 effector cells that can exacerbate autoimmunity...
  9. ncbi request reprint Transforming growth factor-beta induces development of the T(H)17 lineage
    Paul R Mangan
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294 2170, USA
    Nature 441:231-4. 2006
    ..The action of TGF-beta on naive T cells is antagonized by interferon-gamma and IL-4, thus providing a mechanism for divergence of the T(H)1, T(H)2 and T(H)17 lineages...
  10. pmc T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis
    Nuzhat Iqbal
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    J Exp Med 195:71-84. 2002
    ....
  11. pmc MMP induced by Gr-1+ cells are crucial for recruitment of Th cells into the airways
    Yong Woo Jung
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Eur J Immunol 39:2281-92. 2009
    ..These data suggest that antigen challenge via the airway activates Gr-1(+) cells and consequently MMP to facilitate the recruitment of Th cells in the airway inflammatory response...
  12. ncbi request reprint Immunology. T-bet or not T-bet
    Robin D Hatton
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Science 302:993-4. 2003
  13. ncbi request reprint Expanding the effector CD4 T-cell repertoire: the Th17 lineage
    Laurie E Harrington
    Department of Pathology, University of Alabama at Birmingham, 845 19th Street South, Birmingham, AL 35294, USA
    Curr Opin Immunol 18:349-56. 2006
    ....
  14. pmc Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage
    Ryuta Mukasa
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Immunity 32:616-27. 2010
    ....
  15. pmc Late developmental plasticity in the T helper 17 lineage
    Yun Kyung Lee
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Immunity 30:92-107. 2009
    ..These results support a model of late Th17 developmental plasticity with implications for autoimmunity and host defense...
  16. pmc Both Th1 and Th2 cells require P-selectin glycoprotein ligand-1 for optimal rolling on inflamed endothelium
    Paul R Mangan
    Department of Pathology, University of Alabama at Birmingham, USA
    Am J Pathol 167:1661-75. 2005
    ....
  17. ncbi request reprint Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10
    Craig L Maynard
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Nat Immunol 8:931-41. 2007
    ..Thus, Foxp3(+) and Foxp3(-) precursor cells give rise to peripheral IL-10-expressing T(reg) cells by a mechanism dependent on transforming growth factor-beta and independent of IL-10...
  18. pmc Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli
    Anand Balasubramani
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Immunity 33:35-47. 2010
    ..These results support a model of Ifng regulation in which distal cis-regulatory elements differentially recruit key transcription factors in a modular fashion to initiate gene transcription induced by distinct activation signals...
  19. pmc Noninvasive bioluminescence imaging in small animals
    Kurt R Zinn
    Laboratory of Multimodal Imaging, University of Alabama, Birmingham, AL 35294 0012, USA
    ILAR J 49:103-15. 2008
    ..In summary, bioluminescence imaging has become an important component of biomedical research that will continue in the future...
  20. doi request reprint Memory CD4 T cells emerge from effector T-cell progenitors
    Laurie E Harrington
    Department of Pathology, University of Alabama at Birmingham, 845 19th Street South, Birmingham, Alabama 35294, USA
    Nature 452:356-60. 2008
    ..We find that, in parallel with effector CD8 T cells, IFN-gamma-positive effector CD4 T cells give rise to long-lived memory T cells capable of anamnestic responses to antigenic rechallenge...
  21. ncbi request reprint Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice
    Charles O Elson
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 0007, USA
    Gastroenterology 132:2359-70. 2007
    ..Interleukin (IL)-23 supports a distinct lineage of T cells producing IL-17 (Th17) that can mediate chronic inflammation. This study was performed to define the role of IL-23 and Th17 cells in chronic colitis in mice...
  22. pmc Intestinal effector T cells in health and disease
    Craig L Maynard
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Immunity 31:389-400. 2009
    ..In this review, we highlight recent advances in our understanding of effector T cell biology in the context of intestinal immune regulation and speculate on their potential clinical significance...
  23. pmc TGF-beta promotes Th17 cell development through inhibition of SOCS3
    Hongwei Qin
    Department of Cell Biology, University of Alabama at Birmingham, 35294, USA
    J Immunol 183:97-105. 2009
    ..Our data indicate that inhibition of SOCS3 and, thus, enhancement of STAT3 activation is at least one of the mechanisms of TGF-beta promotion of Th17 cell development...
  24. doi request reprint Developmental plasticity of Th17 and Treg cells
    Yun Kyung Lee
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Curr Opin Immunol 21:274-80. 2009
    ....
  25. doi request reprint Autoimmunity: increasing suspects in the CD4+ T cell lineup
    Matthew T Palmer
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Nat Immunol 11:36-40. 2010
    ..Here we speculate on the respective contributions to autoimmunity made by an increasingly complex list of T(H) subsets and argue that the T(H)1 phenotype may be staging a comeback...
  26. ncbi request reprint A distal conserved sequence element controls Ifng gene expression by T cells and NK cells
    Robin D Hatton
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Immunity 25:717-29. 2006
    ..Thus, a single distal element may be essential for Ifng gene expression by both innate and adaptive immune effector cell lineages...
  27. ncbi request reprint Enhancement of MHC class II-restricted responses by receptor-mediated uptake of peptide antigens
    Lolita Zaliauskiene
    Department of Pathology, University of Alabama, Birmingham 35294, USA
    J Immunol 169:2337-45. 2002
    ..Our results demonstrate that coupling peptides to Tf enhances peptide presentation, thereby making it possible to take full advantage of peptide-specific therapies in modulating T cell responses...
  28. pmc Antigen and lipopolysaccharide play synergistic roles in the effector phase of airway inflammation in mice
    Yong Woo Jung
    Department of Pathology, University of Alabama at Birmingham, 35294 2170, USA
    Am J Pathol 168:1425-34. 2006
    ..Our findings demonstrate the importance of both antigen and endotoxin acting in a synergistic manner in the development of airway inflammation...
  29. pmc Pronounced virus-dependent activation drives exhaustion but sustains IFN-γ transcript levels
    Kathryn J Mackerness
    Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Immunol 185:3643-51. 2010
    ..Thus, posttranscription regulatory mechanisms likely disable this effector module...
  30. ncbi request reprint Gene disruption and immunity in experimental colitis
    Charles O Elson
    Division of Gastroenterology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0007, USA
    Inflamm Bowel Dis 10:S25-8. 2004
  31. pmc Efficient adenovirus-mediated gene transfer into primary T cells and thymocytes in a new coxsackie/adenovirus receptor transgenic model
    Vincent Hurez
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294 2170, USA
    BMC Immunol 3:4. 2002
    ..However, naive lymphocytes are not readily susceptible to infection with adenoviruses due to insufficient expression of the coxsackie/adenovirus receptor...
  32. ncbi request reprint Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells
    Takekazu Kubo
    Department of Pathology, University of Alabama, Birmingham, AL 35294 2170, USA
    J Immunol 173:7249-58. 2004
    ..Thus, proinflammatory cytokines produced by TLR-activated, mature DCs are required for reversal of Treg anergy, but are not required to overcome Treg suppression...
  33. ncbi request reprint Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota
    Charles O Elson
    Division of Gastroenterology and Hepatology, Department of Medicine, The University of Alabama at Birmingham, Birmingham, AL 35294 0007, USA
    Immunol Rev 206:260-76. 2005
    ..The same is true for both spontaneous models of IBD, C3H/HeJBir and SAMPI/Yit mice. The thesis is advanced that 'multiple hits' or defects in these interacting components is required for IBD to occur in both mouse and human...
  34. pmc Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation
    Craig L Maynard
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294 2170, USA
    Immunol Rev 226:219-33. 2008
    ....
  35. ncbi request reprint Generation of antigen-specific, Foxp3-expressing CD4+ regulatory T cells by inhibition of APC proteosome function
    Yingzi Cong
    Division of Gastroenterology and Hepatology, Department of Medicine, University of Alabama, Birmingham, AL 35294, USA
    J Immunol 174:2787-95. 2005
    ..We conclude that NF-kappaB-blocked, immature APC are able to induce the differentiation of Treg cells that can function in vitro and in vivo in an Ag-specific manner...
  36. ncbi request reprint Inhibition of T cell responses by transferrin-coupled competitor peptides
    Lolita Zaliauskiene
    Department of Cell Biology and the UAB Comprehensive Cancer Center, University of Alabama at Birmingham, 35294 0005, USA
    Immunol Res 26:77-85. 2002
    ..10 transgenic mouse as our model system...
  37. doi request reprint Emergence of the Th17 pathway and its role in host defense
    Darrell B O'Quinn
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Adv Immunol 99:115-63. 2008
    ..Here we review the experimental history that ultimately uncovered the existence and nature of Th17 cells, and then turn the reader's attention to what is currently known about Th17 cells as a bulwark against pathogens...
  38. ncbi request reprint Development of dermatitis in CD18-deficient PL/J mice is not dependent on bacterial flora, and requires both CD4+ and CD8+ T lymphocytes
    Shayne C Barlow
    Department of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Int Immunol 16:345-51. 2004
    ..These mice may therefore be useful in identifying potential mechanisms of pathogenesis and genetic predisposition in human inflammatory skin diseases...
  39. pmc Restricted clonal expression of IL-2 by naive T cells reflects differential dynamic interactions with dendritic cells
    Vincent Hurez
    Department of Pathology, University of Alabama at Birmingham, AL 35294, USA
    J Exp Med 198:123-32. 2003
    ..Thus, there is intrinsic variability in clonal T cell populations that restricts IL-2 commitment, and prolonged engagement with mature DCs is necessary, but not sufficient, for IL-2 gene transcription...
  40. pmc Effector and suppressor roles for LFA-1 during the development of experimental autoimmune encephalomyelitis
    Kari J Dugger
    Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, United States
    J Neuroimmunol 206:22-7. 2009
    ..Thus, LFA-1 acts as a key regulatory adhesion molecule during the development of EAE, serving both pro- and anti-inflammatory roles in disease pathogenesis...
  41. ncbi request reprint Cutting-edge technology: IV. Genomic engineering for studies of the gastrointestinal tract in mice
    Daniel C Bullard
    Department of Genomics and Pathobiology, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Am J Physiol Gastrointest Liver Physiol 283:G1232-7. 2002
    ....
  42. pmc Psoriasiform dermatitis susceptibility in Itgb2(tm1Bay) PL/J mice requires low-level CD18 expression and at least two additional loci for progression to severe disease
    Shayne C Barlow
    Department of Genomics and Pathobiology, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Am J Pathol 163:197-202. 2003
    ..The susceptibility allele can act in either a heterozygous or homozygous state, dependent on the level of CD18 expression...
  43. ncbi request reprint The genetics of inflammatory bowel disease
    Judy H Cho
    Inflammatory Bowel Disease Center, Section of Digestive Diseases, Yale University, New Haven, Connecticut 06520 8019, USA
    Gastroenterology 133:1327-39. 2007
  44. pmc P-selectin can support both Th1 and Th2 lymphocyte rolling in the intestinal microvasculature
    Claudine S Bonder
    Immunology, Department of Physiology and Biophysics, Faculty of Medicine, University of Calgary, Alberta, Canada
    Am J Pathol 167:1647-60. 2005
    ....
  45. ncbi request reprint Delayed lupus onset in (NZB x NZW)F1 mice expressing a human C-reactive protein transgene
    Alexander J Szalai
    The University of Alabama at Birmingham
    Arthritis Rheum 48:1602-11. 2003
    ..To test whether CRP participates in the pathogenesis of systemic lupus erythematosus (SLE), we examined disease development in lupus-prone (NZB x NZW)F(1) (NZB/NZW) mice expressing a human CRP transgene (hCRPtg/BW)...
  46. ncbi request reprint Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora
    Yingzi Cong
    Division of Gastroenterology and Hepatology, University of Alabama, Birmingham 35294, USA
    J Immunol 169:6112-9. 2002
    ..We conclude that CD4(+) T cells with the properties of Tr1 cells are present in the intestinal lamina propria and hypothesize that these cells maintain intestinal immune homeostasis to the enteric flora...
  47. ncbi request reprint IFN-gamma-inducible chemokines enhance adaptive immunity and colitis
    Udai P Singh
    Department of Microbiology and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Interferon Cytokine Res 23:591-600. 2003
    ..Taken together, these studies suggest that IP-10, MIG, I-TAC, and CXCR3 interactions are involved in mucosal immune responses required for the induction of CD...
  48. pmc Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation
    R Lee Reinhardt
    Department of Microbiology and the Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA
    J Exp Med 197:751-62. 2003
    ....
  49. ncbi request reprint Immunology: narcissistic helpers
    Matthew T Palmer
    Nature 448:416-8. 2007
  50. ncbi request reprint Vitamin A enhances in vitro Th2 development via retinoid X receptor pathway
    Charles B Stephensen
    U S Department of Agriculture Western Human Nutrition Research Center and Nutrition Department, University of California, Davis, CA 95616, USA
    J Immunol 168:4495-503. 2002
    ..These data show that stimulation of the RXR pathway enhances Th2 development, perhaps by affecting the relative expression of pertinent transcription factors, cytokines, and cytokine receptors...
  51. doi request reprint The central role of the Th17 lineage in regulating the inflammatory/autoimmune axis
    Casey T Weaver
    Semin Immunol 19:351-2. 2007

Research Grants20

  1. Control of chromatin landscapes in effector T cell lineage specifications
    Casey Weaver; Fiscal Year: 2009
    ..abstract_text> ..
  2. Post-Thymic T-Cell Functional Heterogeneity
    Casey Weaver; Fiscal Year: 2006
    ..We anticipate that successful completion of these studies will provide an understanding of CD4 T lineage effector and memory cell development that will suggest improved strategies for vaccine development and immunotherapy...
  3. Post-Thymic T-Cell Functional Heterogeneity
    Casey Weaver; Fiscal Year: 2007
    ..We anticipate that successful completion of these studies will provide an understanding of CD4 T lineage effector and memory cell development that will suggest improved strategies for vaccine development and immunotherapy...
  4. Immune Regulation to Intestinal Bacterial Antigens
    Casey Weaver; Fiscal Year: 2007
    ..These studies will provide a basis for manipulation of Treg function as a therapeutic approach to restoring dysregulated T cell responses in IBD. ..
  5. Post-Thymic T-Cell Functional Heterogeneity
    Casey Weaver; Fiscal Year: 2009
    ..We anticipate that successful completion of these studies will provide an understanding of CD4 T lineage effector and memory cell development that will suggest improved strategies for vaccine development and immunotherapy...
  6. Post-Thymic T-Cell Functional Heterogeneity
    Casey T Weaver; Fiscal Year: 2010
    ..We anticipate that successful completion of these studies will provide an understanding of CD4 T lineage effector and memory cell development that will suggest improved strategies for vaccine development and immunotherapy...
  7. Immune Regulation to Intestinal Bacterial Antigens
    Casey Weaver; Fiscal Year: 2006
    ..These studies will provide a basis for manipulation of Treg function as a therapeutic approach to restoring dysregulated T cell responses in IBD. ..
  8. Immune Regulation to Intestinal Bacterial Antigens
    Casey Weaver; Fiscal Year: 2005
    ..These studies will provide a basis for manipulation of Treg function as a therapeutic approach to restoring dysregulated T cell responses in IBD. ..
  9. POSTTHYMIC T CELL FUNCTIONAL REPERTOIRE HETEROGENEITY
    Casey Weaver; Fiscal Year: 1999
    ....
  10. POSTTHYMIC T CELL FUNCTIONAL REPERTOIRE HETEROGENEITY
    Casey Weaver; Fiscal Year: 2000
    ....
  11. POSTTHYMIC T CELL FUNCTIONAL REPERTOIRE HETEROGENEITY
    Casey Weaver; Fiscal Year: 2001
    ....
  12. POSTTHYMIC T CELL FUNCTIONAL REPERTOIRE HETEROGENEITY
    Casey Weaver; Fiscal Year: 2002
    ....
  13. Development and Maintenance of Intestinal Regulatory T Cells
    Casey Weaver; Fiscal Year: 2003
    ..These studies will provide a basis for manipulation of Treg function as a therapeutic approach to restoring dysregulated T cell responses in IBD. ..
  14. Immune Regulation to Intestinal Bacterial Antigens
    Casey Weaver; Fiscal Year: 2004
    ..These studies will provide a basis for manipulation of Treg function as a therapeutic approach to restoring dysregulated T cell responses in IBD. ..
  15. Control of chromatin landscapes in effector T cell lineage specifications
    Casey T Weaver; Fiscal Year: 2010
    ..abstract_text> ..