R K Wayne

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Evolutionary genomics of dog domestication
    Robert K Wayne
    Department of Ecology and Evolutionary Biology, University of California, 610 Charles E Young Drive South, Los Angeles, CA 90095 1606, USA
    Mamm Genome 23:3-18. 2012
  2. pmc A comparison of variation between a MHC pseudogene and microsatellite loci of the little greenbul (Andropadus virens)
    Andres Aguilar
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 USA
    BMC Evol Biol 5:47. 2005
  3. pmc Multigene phylogeny of the Mustelidae: resolving relationships, tempo and biogeographic history of a mammalian adaptive radiation
    Klaus Peter Koepfli
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, 90095 1606, USA
    BMC Biol 6:10. 2008
  4. pmc Extensive population genetic structure in the giraffe
    David M Brown
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, 90095, USA
    BMC Biol 5:57. 2007
  5. pmc The IGF1 small dog haplotype is derived from Middle Eastern grey wolves
    Melissa M Gray
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, USA
    BMC Biol 8:16. 2010
  6. ncbi request reprint Origin, genetic diversity, and genome structure of the domestic dog
    R K Wayne
    Department of Biology, University of California, Los Angeles 90095 1606, USA
    Bioessays 21:247-57. 1999
  7. ncbi request reprint Lessons learned from the dog genome
    Robert K Wayne
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 91302, USA
    Trends Genet 23:557-67. 2007
  8. pmc Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication
    Bridgett M VonHoldt
    Department of Ecology and Evolutionary Biology, 621 Charles E Young Drive South, University of California, Los Angeles, California 90095, USA
    Nature 464:898-902. 2010
  9. ncbi request reprint Phylogenetic relationships, evolution, and genetic diversity of the domestic dog
    C Vila
    Department of Biology, University of California, Los Angeles, USA
    J Hered 90:71-7. 1999
  10. doi request reprint Landscape genetics of California mule deer (Odocoileus hemionus): the roles of ecological and historical factors in generating differentiation
    Katherine M Pease
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA
    Mol Ecol 18:1848-62. 2009

Detail Information

Publications52

  1. doi request reprint Evolutionary genomics of dog domestication
    Robert K Wayne
    Department of Ecology and Evolutionary Biology, University of California, 610 Charles E Young Drive South, Los Angeles, CA 90095 1606, USA
    Mamm Genome 23:3-18. 2012
    ....
  2. pmc A comparison of variation between a MHC pseudogene and microsatellite loci of the little greenbul (Andropadus virens)
    Andres Aguilar
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 USA
    BMC Evol Biol 5:47. 2005
    ..Previous microsatellite and mitochondrial DNA analyses had revealed little or no genetic differentiation among Cameroon localities but significant differentiation between localities in Cameroon and Ivory Coast...
  3. pmc Multigene phylogeny of the Mustelidae: resolving relationships, tempo and biogeographic history of a mammalian adaptive radiation
    Klaus Peter Koepfli
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, 90095 1606, USA
    BMC Biol 6:10. 2008
    ....
  4. pmc Extensive population genetic structure in the giraffe
    David M Brown
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, 90095, USA
    BMC Biol 5:57. 2007
    ....
  5. pmc The IGF1 small dog haplotype is derived from Middle Eastern grey wolves
    Melissa M Gray
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, USA
    BMC Biol 8:16. 2010
    ....
  6. ncbi request reprint Origin, genetic diversity, and genome structure of the domestic dog
    R K Wayne
    Department of Biology, University of California, Los Angeles 90095 1606, USA
    Bioessays 21:247-57. 1999
    ..The dog promises to be a valuable model for identifying genes that control morphologic differences between mammals as well as understanding genetically based disease...
  7. ncbi request reprint Lessons learned from the dog genome
    Robert K Wayne
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 91302, USA
    Trends Genet 23:557-67. 2007
    ..The dog is finally emerging as a novel resource for studying the genetic basis of complex traits, including behavior...
  8. pmc Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication
    Bridgett M VonHoldt
    Department of Ecology and Evolutionary Biology, 621 Charles E Young Drive South, University of California, Los Angeles, California 90095, USA
    Nature 464:898-902. 2010
    ..More recently, the evolution of modern dog breeds seems to have been an iterative process that drew on a limited genetic toolkit to create remarkable phenotypic diversity...
  9. ncbi request reprint Phylogenetic relationships, evolution, and genetic diversity of the domestic dog
    C Vila
    Department of Biology, University of California, Los Angeles, USA
    J Hered 90:71-7. 1999
    ..Other breeds are also genetically diverse, suggesting that dog breeds were often founded with a large number of dogs from outbred populations...
  10. doi request reprint Landscape genetics of California mule deer (Odocoileus hemionus): the roles of ecological and historical factors in generating differentiation
    Katherine M Pease
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA
    Mol Ecol 18:1848-62. 2009
    ..Geographic differences in the timing of reproduction and peak vegetation as well as habitat choice reflecting natal origin may explain the persistence of genetic subdivision...
  11. doi request reprint Divergence with gene flow and fine-scale phylogeographical structure in the wedge-billed woodcreeper, Glyphorynchus spirurus, a Neotropical rainforest bird
    B Mila
    Center for Tropical Research, Institute for the Environment, University of California, 619 Charles Young Dr, Los Angeles, CA 90095 1496, USA
    Mol Ecol 18:2979-95. 2009
    ..Our results support the predominant role of geographical isolation in driving genetic differentiation in G. spirurus, yet suggest the role of selection in driving parallel morphological divergence along ecological gradients...
  12. ncbi request reprint Tripartite genetic subdivisions in the ornate shrew (Sorex ornatus)
    J E Maldonado
    Department of Organismic Biology, Ecology and Evolution, University of California, Los Angeles 90095 1606, USA
    Mol Ecol 10:127-47. 2001
    ....
  13. pmc Estimating population size by genotyping faeces
    M H Kohn
    Department of Biology, University of California, Los Angeles 90095 1606, USA
    Proc Biol Sci 266:657-63. 1999
    ..This method readily provides a point count estimate of population size and sex ratio. Additionally, we show that home range use paternity and kinship can be inferred from the distribution and relatedness patterns of faecal genotypes...
  14. ncbi request reprint Ancient DNA evidence for Old World origin of New World dogs
    Jennifer A Leonard
    Department of Organismic Biology, Ecology and Evolution, University of California, Los Angeles, CA 90095 1606, USA
    Science 298:1613-6. 2002
    ..This unique clade was absent from a large sample of modern dogs, which implies that European colonists systematically discouraged the breeding of native American dogs...
  15. ncbi request reprint Patterns of population subdivision, gene flow and genetic variability in the African wild dog (Lycaon pictus)
    D J Girman
    Department of Biology, Sonoma State University, Rohnert Park, CA, USA
    Mol Ecol 10:1703-23. 2001
    ..In contrast, gene flow estimates based on the mtDNA control region were lower than expected given differences in the mode of inheritance of mitochondrial and nuclear markers which suggests a male bias in long-distance dispersal...
  16. pmc High MHC diversity maintained by balancing selection in an otherwise genetically monomorphic mammal
    Andres Aguilar
    Department of Organismic Biology, Ecology, and Evolution, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 101:3490-4. 2004
    ..5 on MHC loci. These results support the importance of balancing selection as a mechanism to maintain variation in natural populations and expose the difficulty of using neutral markers as surrogates for variation in fitness-related loci...
  17. pmc Natural selection mapping of the warfarin-resistance gene
    M H Kohn
    Department of Organismic Biology, Ecology, and Evolution OBEE, University of California, Los Angeles, USA
    Proc Natl Acad Sci U S A 97:7911-5. 2000
    ....
  18. ncbi request reprint Empirical evaluation of preservation methods for faecal DNA
    M A Frantzen
    Department of Zoology and Entomology, University of Pretoria, South Africa
    Mol Ecol 7:1423-8. 1998
    ..A review of molecular scatology studies further suggests that three to six faeces per individual should be collected...
  19. ncbi request reprint Testing alternative mechanisms of evolutionary divergence in an African rain forest passerine bird
    T B Smith
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 1496, USA
    J Evol Biol 18:257-68. 2005
    ....
  20. pmc Linkage disequilibrium and demographic history of wild and domestic canids
    Melissa M Gray
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90032, USA
    Genetics 181:1493-505. 2009
    ..Only a 5% reduction in nucleotide diversity was observed as a result of domestication, whereas the loss of nucleotide diversity with breed formation averaged 35%...
  21. ncbi request reprint Speciation and rapid phenotypic differentiation in the yellow-rumped warbler Dendroica coronata complex
    Borja Milá
    Department of Ecology and Evolutionary Biology, University of California Los Angeles, 621 Charles E Young Dr, Los Angeles, CA 90095, USA
    Mol Ecol 16:159-73. 2007
    ....
  22. ncbi request reprint Postglacial population expansion drives the evolution of long-distance migration in a songbird
    Borja Milá
    Department of Ecology and Evolutionary Biology, University of California, 621 Charles E Young Drive, Los Angeles, California 90095, USA
    Evolution 60:2403-9. 2006
    ....
  23. ncbi request reprint Phylogeny of the Procyonidae (Mammalia: Carnivora): molecules, morphology and the Great American Interchange
    Klaus Peter Koepfli
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 1606, USA
    Mol Phylogenet Evol 43:1076-95. 2007
    ....
  24. ncbi request reprint Molecular systematics of the Hyaenidae: relationships of a relictual lineage resolved by a molecular supermatrix
    Klaus Peter Koepfli
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 1606, USA
    Mol Phylogenet Evol 38:603-20. 2006
    ..Hyaenidae; phylogeny; cytochrome b; nuclear gene segments; Proteles; Crocuta; Hyaena; Parahyaena.]...
  25. pmc Selective sweep mapping of genes with large phenotypic effects
    John P Pollinger
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, California 90095 1606, USA
    Genome Res 15:1809-19. 2005
    ..This region contains the FGFR3 gene, which is responsible for achondroplasia in humans, but not in dogs. Consequently, our results suggest that the causative mutation is a gene or regulatory region closely linked to FGFR3...
  26. doi request reprint Spatial modelling and landscape-level approaches for visualizing intra-specific variation
    Henri A Thomassen
    Center for Tropical Research, Institute of the Environment, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Mol Ecol 19:3532-48. 2010
    ..In the final section, we discuss some of the key challenges and opportunities for future work...
  27. ncbi request reprint Type I STS markers are more informative than cytochrome B in phylogenetic reconstruction of the Mustelidae (Mammalia: Carnivora)
    Klaus Peter Koepfli
    Department of Organismic Biology, Ecology and Evolution, 621 Charles E Young Drive South, University of California, Los Angeles, California 90095 1606, USA
    Syst Biol 52:571-93. 2003
    ....
  28. ncbi request reprint A molecular phylogeny of the Canidae based on six nuclear loci
    Carolyne Bardeleben
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 1606, USA
    Mol Phylogenet Evol 37:815-31. 2005
    ..The lack of resolution within the wolf-like canids may be due to their recent divergence and insufficient time for the accumulation of phylogenetically informative signal...
  29. doi request reprint A novel assessment of population structure and gene flow in grey wolf populations of the Northern Rocky Mountains of the United States
    Bridgett M VonHoldt
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA
    Mol Ecol 19:4412-27. 2010
    ..Successful conservation of Northern Rocky Mountain wolves will rely on management decisions that promote natural dispersal dynamics and minimize anthropogenic factors that reduce genetic connectivity...
  30. ncbi request reprint Microsatellite analysis of kinkajou social organization
    R W Kays
    Department of Ecology and Evolutionary Biology, University of Tennessee, Knoxville, TN, 37996, USA
    Mol Ecol 9:743-51. 2000
    ..Neighbouring male kinkajous were more closely related to each other than neighbouring female kinkajous, suggesting that females disperse more often or farther than males...
  31. ncbi request reprint Examining monophyly in a large radiation of Madagascan butterflies (Lepidoptera: Satyrinae: Mycalesina) based on mitochondrial DNA data
    E Torres
    Department of Biology and Microbiology, California State University, Los Angeles, California 90032-8201, USA
    Mol Phylogenet Evol 20:460-73. 2001
    ..Dense taxon sampling appears to be crucial for elucidating phylogenetic relationships within this large radiation. A potentially complex scenario for the origin of Malagasy mycalesines is proposed...
  32. pmc Native Great Lakes wolves were not restored
    Jennifer A Leonard
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA
    Biol Lett 4:95-8. 2008
    ..Consequently, the pre-recovery population has not been restored, casting doubt on delisting actions...
  33. ncbi request reprint Isolation and molecular evolution of the selenocysteine tRNA (Cf TRSP) and RNase P RNA (Cf RPPH1) genes in the dog family, Canidae
    Carolyne Bardeleben
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, USA
    Mol Biol Evol 22:347-59. 2005
    ..Gene trees generated from the TRSP and RPPH1 loci were generally in agreement with the published mtDNA phylogeny and are the first phylogeny of Canidae based on nuclear sequences...
  34. ncbi request reprint A new phylogenetic marker, apolipoprotein B, provides compelling evidence for eutherian relationships
    Heather Amrine-Madsen
    Department of Biology, University of California, Riverside 92521, USA
    Mol Phylogenet Evol 28:225-40. 2003
    ..A smaller deletion of 237-246bp was diagnostic of the superordinal clade Afrotheria...
  35. pmc Recent postglacial range expansion drives the rapid diversification of a songbird lineage in the genus Junco
    Borja Milá
    Department of Ecology and Evolutionary Biology, University of California Los Angeles, 621 Charles E Young Drive, Los Angeles, CA 90095, USA
    Proc Biol Sci 274:2653-60. 2007
    ..These results underscore the role of postglacial expansions in promoting diversification and speciation through a mechanism that represents an alternative to traditional modes of Pleistocene speciation...
  36. ncbi request reprint Transgressive segregation, adaptation and speciation
    L H Rieseberg
    Department of Biology, Indiana University, Bloomington, IN 47405, USA
    Heredity (Edinb) 83:363-72. 1999
    ..These results lend credence to the view that hybridization may provide the raw material for rapid adaptation and provide a simple explanation for niche divergence and phenotypic novelty often associated with hybrid lineages...
  37. pmc Locus-specific genetic differentiation at Rw among warfarin-resistant rat (Rattus norvegicus) populations
    Michael H Kohn
    Department of Organismic Biology, Ecology, and Evolution OBEE, University of California, Los Angeles, California 90095 1606, USA
    Genetics 164:1055-70. 2003
    ....
  38. ncbi request reprint Megafaunal extinctions and the disappearance of a specialized wolf ecomorph
    Jennifer A Leonard
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA
    Curr Biol 17:1146-50. 2007
    ..Consequently, the survival of the species in North America depended on the presence of more generalized forms elsewhere...
  39. ncbi request reprint Genomics and conservation genetics
    Michael H Kohn
    Department of Ecology and Evolutionary Biology, Rice University, MS 170, 6100 Main Street, Houston, TX 77005, USA
    Trends Ecol Evol 21:629-37. 2006
    ..A new conservation genetic agenda would utilize data from enhanced surveys of genomic variation in endangered species to better manage functional genetic variation...
  40. ncbi request reprint The genealogy and genetic viability of reintroduced Yellowstone grey wolves
    Bridgett M VonHoldt
    University of California, Los Angeles, Ecology and Evolutionary Biology, 621 Charles E Young Dr South, Los Angeles, CA 90095, USA
    Mol Ecol 17:252-74. 2008
    ..Although short-term losses in variation seem minimal, future projections of the population at carrying capacity suggest significant inbreeding depression will occur without connectivity and migratory exchange with other populations...
  41. ncbi request reprint Molecular systematics of the Canidae
    R K Wayne
    Department of Biology, University of California, Los Angeles, California 90095, USA
    Syst Biol 46:622-53. 1997
    ..However, the homogeneity partition tests indicate significant heterogeneity between the two data sets...
  42. ncbi request reprint Microsatellite analysis of female mating behaviour in lek-breeding sage grouse
    K Semple
    Department of Organismic Biology, Ecology and Evolution, University of California at Los Angeles, Los Angeles, CA 90095-1606, USA
    Mol Ecol 10:2043-8. 2001
    ..Radio-tracking suggested that two of these females mated at other leks. Our results confirm the reliability of mating observations at leks, but do not rule out a possible unseen component of the mating system...
  43. ncbi request reprint Patterns of variation in MHC class II beta loci of the little greenbul (Andropadus virens) with comments on MHC evolution in birds
    Andres Aguilar
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA
    J Hered 97:133-42. 2006
    ..virens genomic or transcribed MHC sequences. The use of conserved MHC primers followed by analysis of cloned sequences allows rapid isolation of MHC loci from exotic species and avoids laborious large-scale cloning and sequencing...
  44. ncbi request reprint Legacy lost: genetic variability and population size of extirpated US grey wolves (Canis lupus)
    Jennifer A Leonard
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 1606, USA
    Mol Ecol 14:9-17. 2005
    ....
  45. ncbi request reprint A southern California freeway is a physical and social barrier to gene flow in carnivores
    Seth P D Riley
    Department of Ecology and Evolutionary Biology, 621 Charles Young Dr South, University of California, Los Angeles, CA 90095, USA
    Mol Ecol 15:1733-41. 2006
    ....
  46. ncbi request reprint Sea ice occurrence predicts genetic isolation in the Arctic fox
    Eli Geffen
    Department of Zoology Tel Aviv University, 69978 Tel Aviv, Israel
    Mol Ecol 16:4241-55. 2007
    ..In addition, our analysis identified the Commander and Pribilof Islands Arctic populations as genetically unique suggesting they deserve special attention from a conservation perspective...
  47. ncbi request reprint Differentiation of tundra/taiga and boreal coniferous forest wolves: genetics, coat colour and association with migratory caribou
    Marco Musiani
    Faculty of Environmental Design, University of Calgary, Calgary, AB, Canada T2N 1 N4
    Mol Ecol 16:4149-70. 2007
    ..The presence of a distinct wolf ecotype in the tundra of North America highlights the need to preserve migratory populations...
  48. pmc A single IGF1 allele is a major determinant of small size in dogs
    Nathan B Sutter
    National Human Genome Research Institute, Building 50, Room 5349, 50 South Drive MSC 8000, Bethesda, MD 20892 8000, USA
    Science 316:112-5. 2007
    ..A single IGF1 single-nucleotide polymorphism haplotype is common to all small breeds and nearly absent from giant breeds, suggesting that the same causal sequence variant is a major contributor to body size in all small dogs...
  49. ncbi request reprint Genome sequence, comparative analysis and haplotype structure of the domestic dog
    Kerstin Lindblad-Toh
    Broad Institute of Harvard and MIT, 320 Charles Street, Cambridge, Massachusetts 02141, USA
    Nature 438:803-19. 2005
    ..The current SNP map now makes it possible for genome-wide association studies to identify genes responsible for diseases and traits, with important consequences for human and companion animal health...
  50. ncbi request reprint The canine genome
    Elaine A Ostrander
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genome Res 15:1706-16. 2005
    ..We suggest that given these resources and the unique characteristics of breeds, that the dog is a uniquely valuable resource for studying the genetic basis of complex traits...
  51. ncbi request reprint Microsatellite DNA analysis shows that greater sage grouse leks are not kin groups
    Robert M Gibson
    School of Biological Sciences, University of Nebraska Lincoln, NE 68588 0118, USA
    Mol Ecol 14:4453-9. 2005
    ..Together with other recent studies, they also raise the question of why kin selection apparently promotes social courtship in some lekking species, but not in others...
  52. ncbi request reprint Climate and habitat barriers to dispersal in the highly mobile grey wolf
    Eli Geffen
    Institute for Nature Conservation Research Tel Aviv University Tel Aviv 69978 Israel
    Mol Ecol 13:2481-90. 2004
    ..We suggest two possible mechanisms by which environmental conditions may influence the dispersal decisions made by wolves...