Research Topics
| R K WayneSummaryAffiliation: University of California Country: USA Publications
| Collaborators
|
Detail Information
Publications
Evolutionary genomics of dog domesticationRobert K Wayne
Department of Ecology and Evolutionary Biology, University of California, 610 Charles E Young Drive South, Los Angeles, CA 90095 1606, USA
Mamm Genome 23:3-18. 2012....
A comparison of variation between a MHC pseudogene and microsatellite loci of the little greenbul (Andropadus virens)Andres Aguilar
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 USA
BMC Evol Biol 5:47. 2005..Previous microsatellite and mitochondrial DNA analyses had revealed little or no genetic differentiation among Cameroon localities but significant differentiation between localities in Cameroon and Ivory Coast...- Multigene phylogeny of the Mustelidae: resolving relationships, tempo and biogeographic history of a mammalian adaptive radiationKlaus Peter Koepfli
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, 90095 1606, USA
BMC Biol 6:10. 2008.... - Extensive population genetic structure in the giraffeDavid M Brown
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, 90095, USA
BMC Biol 5:57. 2007.... - The IGF1 small dog haplotype is derived from Middle Eastern grey wolvesMelissa M Gray
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, USA
BMC Biol 8:16. 2010.... 
Origin, genetic diversity, and genome structure of the domestic dogR K Wayne
Department of Biology, University of California, Los Angeles 90095 1606, USA
Bioessays 21:247-57. 1999..The dog promises to be a valuable model for identifying genes that control morphologic differences between mammals as well as understanding genetically based disease...- Lessons learned from the dog genomeRobert K Wayne
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 91302, USA
Trends Genet 23:557-67. 2007..The dog is finally emerging as a novel resource for studying the genetic basis of complex traits, including behavior... - Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domesticationBridgett M VonHoldt
Department of Ecology and Evolutionary Biology, 621 Charles E Young Drive South, University of California, Los Angeles, California 90095, USA
Nature 464:898-902. 2010..More recently, the evolution of modern dog breeds seems to have been an iterative process that drew on a limited genetic toolkit to create remarkable phenotypic diversity... - Phylogenetic relationships, evolution, and genetic diversity of the domestic dogC Vila
Department of Biology, University of California, Los Angeles, USA
J Hered 90:71-7. 1999..Other breeds are also genetically diverse, suggesting that dog breeds were often founded with a large number of dogs from outbred populations... - Landscape genetics of California mule deer (Odocoileus hemionus): the roles of ecological and historical factors in generating differentiationKatherine M Pease
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA
Mol Ecol 18:1848-62. 2009..Geographic differences in the timing of reproduction and peak vegetation as well as habitat choice reflecting natal origin may explain the persistence of genetic subdivision... - Divergence with gene flow and fine-scale phylogeographical structure in the wedge-billed woodcreeper, Glyphorynchus spirurus, a Neotropical rainforest birdB Mila
Center for Tropical Research, Institute for the Environment, University of California, 619 Charles Young Dr, Los Angeles, CA 90095 1496, USA
Mol Ecol 18:2979-95. 2009..Our results support the predominant role of geographical isolation in driving genetic differentiation in G. spirurus, yet suggest the role of selection in driving parallel morphological divergence along ecological gradients... - Tripartite genetic subdivisions in the ornate shrew (Sorex ornatus)J E Maldonado
Department of Organismic Biology, Ecology and Evolution, University of California, Los Angeles 90095 1606, USA
Mol Ecol 10:127-47. 2001.... - Estimating population size by genotyping faecesM H Kohn
Department of Biology, University of California, Los Angeles 90095 1606, USA
Proc Biol Sci 266:657-63. 1999..This method readily provides a point count estimate of population size and sex ratio. Additionally, we show that home range use paternity and kinship can be inferred from the distribution and relatedness patterns of faecal genotypes... - Ancient DNA evidence for Old World origin of New World dogsJennifer A Leonard
Department of Organismic Biology, Ecology and Evolution, University of California, Los Angeles, CA 90095 1606, USA
Science 298:1613-6. 2002..This unique clade was absent from a large sample of modern dogs, which implies that European colonists systematically discouraged the breeding of native American dogs... - Patterns of population subdivision, gene flow and genetic variability in the African wild dog (Lycaon pictus)D J Girman
Department of Biology, Sonoma State University, Rohnert Park, CA, USA
Mol Ecol 10:1703-23. 2001..In contrast, gene flow estimates based on the mtDNA control region were lower than expected given differences in the mode of inheritance of mitochondrial and nuclear markers which suggests a male bias in long-distance dispersal... - High MHC diversity maintained by balancing selection in an otherwise genetically monomorphic mammalAndres Aguilar
Department of Organismic Biology, Ecology, and Evolution, University of California, Los Angeles, CA 90095, USA
Proc Natl Acad Sci U S A 101:3490-4. 2004..5 on MHC loci. These results support the importance of balancing selection as a mechanism to maintain variation in natural populations and expose the difficulty of using neutral markers as surrogates for variation in fitness-related loci... - Natural selection mapping of the warfarin-resistance geneM H Kohn
Department of Organismic Biology, Ecology, and Evolution OBEE, University of California, Los Angeles, USA
Proc Natl Acad Sci U S A 97:7911-5. 2000.... - Empirical evaluation of preservation methods for faecal DNAM A Frantzen
Department of Zoology and Entomology, University of Pretoria, South Africa
Mol Ecol 7:1423-8. 1998..A review of molecular scatology studies further suggests that three to six faeces per individual should be collected... - Testing alternative mechanisms of evolutionary divergence in an African rain forest passerine birdT B Smith
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 1496, USA
J Evol Biol 18:257-68. 2005.... - Linkage disequilibrium and demographic history of wild and domestic canidsMelissa M Gray
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90032, USA
Genetics 181:1493-505. 2009..Only a 5% reduction in nucleotide diversity was observed as a result of domestication, whereas the loss of nucleotide diversity with breed formation averaged 35%... - Speciation and rapid phenotypic differentiation in the yellow-rumped warbler Dendroica coronata complexBorja Milá
Department of Ecology and Evolutionary Biology, University of California Los Angeles, 621 Charles E Young Dr, Los Angeles, CA 90095, USA
Mol Ecol 16:159-73. 2007.... - Postglacial population expansion drives the evolution of long-distance migration in a songbirdBorja Milá
Department of Ecology and Evolutionary Biology, University of California, 621 Charles E Young Drive, Los Angeles, California 90095, USA
Evolution 60:2403-9. 2006.... - Phylogeny of the Procyonidae (Mammalia: Carnivora): molecules, morphology and the Great American InterchangeKlaus Peter Koepfli
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 1606, USA
Mol Phylogenet Evol 43:1076-95. 2007.... - Molecular systematics of the Hyaenidae: relationships of a relictual lineage resolved by a molecular supermatrixKlaus Peter Koepfli
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 1606, USA
Mol Phylogenet Evol 38:603-20. 2006..Hyaenidae; phylogeny; cytochrome b; nuclear gene segments; Proteles; Crocuta; Hyaena; Parahyaena.]... - Selective sweep mapping of genes with large phenotypic effectsJohn P Pollinger
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, California 90095 1606, USA
Genome Res 15:1809-19. 2005..This region contains the FGFR3 gene, which is responsible for achondroplasia in humans, but not in dogs. Consequently, our results suggest that the causative mutation is a gene or regulatory region closely linked to FGFR3... - Spatial modelling and landscape-level approaches for visualizing intra-specific variationHenri A Thomassen
Center for Tropical Research, Institute of the Environment, University of California, Los Angeles, Los Angeles, CA 90095, USA
Mol Ecol 19:3532-48. 2010..In the final section, we discuss some of the key challenges and opportunities for future work... - Type I STS markers are more informative than cytochrome B in phylogenetic reconstruction of the Mustelidae (Mammalia: Carnivora)Klaus Peter Koepfli
Department of Organismic Biology, Ecology and Evolution, 621 Charles E Young Drive South, University of California, Los Angeles, California 90095 1606, USA
Syst Biol 52:571-93. 2003.... - A molecular phylogeny of the Canidae based on six nuclear lociCarolyne Bardeleben
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 1606, USA
Mol Phylogenet Evol 37:815-31. 2005..The lack of resolution within the wolf-like canids may be due to their recent divergence and insufficient time for the accumulation of phylogenetically informative signal... - A novel assessment of population structure and gene flow in grey wolf populations of the Northern Rocky Mountains of the United StatesBridgett M VonHoldt
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA
Mol Ecol 19:4412-27. 2010..Successful conservation of Northern Rocky Mountain wolves will rely on management decisions that promote natural dispersal dynamics and minimize anthropogenic factors that reduce genetic connectivity... - Microsatellite analysis of kinkajou social organizationR W Kays
Department of Ecology and Evolutionary Biology, University of Tennessee, Knoxville, TN, 37996, USA
Mol Ecol 9:743-51. 2000..Neighbouring male kinkajous were more closely related to each other than neighbouring female kinkajous, suggesting that females disperse more often or farther than males... - Examining monophyly in a large radiation of Madagascan butterflies (Lepidoptera: Satyrinae: Mycalesina) based on mitochondrial DNA dataE Torres
Department of Biology and Microbiology, California State University, Los Angeles, California 90032-8201, USA
Mol Phylogenet Evol 20:460-73. 2001..Dense taxon sampling appears to be crucial for elucidating phylogenetic relationships within this large radiation. A potentially complex scenario for the origin of Malagasy mycalesines is proposed... - Native Great Lakes wolves were not restoredJennifer A Leonard
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA
Biol Lett 4:95-8. 2008..Consequently, the pre-recovery population has not been restored, casting doubt on delisting actions... - Isolation and molecular evolution of the selenocysteine tRNA (Cf TRSP) and RNase P RNA (Cf RPPH1) genes in the dog family, CanidaeCarolyne Bardeleben
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, USA
Mol Biol Evol 22:347-59. 2005..Gene trees generated from the TRSP and RPPH1 loci were generally in agreement with the published mtDNA phylogeny and are the first phylogeny of Canidae based on nuclear sequences... - A new phylogenetic marker, apolipoprotein B, provides compelling evidence for eutherian relationshipsHeather Amrine-Madsen
Department of Biology, University of California, Riverside 92521, USA
Mol Phylogenet Evol 28:225-40. 2003..A smaller deletion of 237-246bp was diagnostic of the superordinal clade Afrotheria... - Recent postglacial range expansion drives the rapid diversification of a songbird lineage in the genus JuncoBorja Milá
Department of Ecology and Evolutionary Biology, University of California Los Angeles, 621 Charles E Young Drive, Los Angeles, CA 90095, USA
Proc Biol Sci 274:2653-60. 2007..These results underscore the role of postglacial expansions in promoting diversification and speciation through a mechanism that represents an alternative to traditional modes of Pleistocene speciation... - Transgressive segregation, adaptation and speciationL H Rieseberg
Department of Biology, Indiana University, Bloomington, IN 47405, USA
Heredity (Edinb) 83:363-72. 1999..These results lend credence to the view that hybridization may provide the raw material for rapid adaptation and provide a simple explanation for niche divergence and phenotypic novelty often associated with hybrid lineages... - Locus-specific genetic differentiation at Rw among warfarin-resistant rat (Rattus norvegicus) populationsMichael H Kohn
Department of Organismic Biology, Ecology, and Evolution OBEE, University of California, Los Angeles, California 90095 1606, USA
Genetics 164:1055-70. 2003.... - Megafaunal extinctions and the disappearance of a specialized wolf ecomorphJennifer A Leonard
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA
Curr Biol 17:1146-50. 2007..Consequently, the survival of the species in North America depended on the presence of more generalized forms elsewhere... - Genomics and conservation geneticsMichael H Kohn
Department of Ecology and Evolutionary Biology, Rice University, MS 170, 6100 Main Street, Houston, TX 77005, USA
Trends Ecol Evol 21:629-37. 2006..A new conservation genetic agenda would utilize data from enhanced surveys of genomic variation in endangered species to better manage functional genetic variation... - The genealogy and genetic viability of reintroduced Yellowstone grey wolvesBridgett M VonHoldt
University of California, Los Angeles, Ecology and Evolutionary Biology, 621 Charles E Young Dr South, Los Angeles, CA 90095, USA
Mol Ecol 17:252-74. 2008..Although short-term losses in variation seem minimal, future projections of the population at carrying capacity suggest significant inbreeding depression will occur without connectivity and migratory exchange with other populations... - Molecular systematics of the CanidaeR K Wayne
Department of Biology, University of California, Los Angeles, California 90095, USA
Syst Biol 46:622-53. 1997..However, the homogeneity partition tests indicate significant heterogeneity between the two data sets... - Microsatellite analysis of female mating behaviour in lek-breeding sage grouseK Semple
Department of Organismic Biology, Ecology and Evolution, University of California at Los Angeles, Los Angeles, CA 90095-1606, USA
Mol Ecol 10:2043-8. 2001..Radio-tracking suggested that two of these females mated at other leks. Our results confirm the reliability of mating observations at leks, but do not rule out a possible unseen component of the mating system... - Patterns of variation in MHC class II beta loci of the little greenbul (Andropadus virens) with comments on MHC evolution in birdsAndres Aguilar
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA
J Hered 97:133-42. 2006..virens genomic or transcribed MHC sequences. The use of conserved MHC primers followed by analysis of cloned sequences allows rapid isolation of MHC loci from exotic species and avoids laborious large-scale cloning and sequencing... - Legacy lost: genetic variability and population size of extirpated US grey wolves (Canis lupus)Jennifer A Leonard
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095 1606, USA
Mol Ecol 14:9-17. 2005.... - A southern California freeway is a physical and social barrier to gene flow in carnivoresSeth P D Riley
Department of Ecology and Evolutionary Biology, 621 Charles Young Dr South, University of California, Los Angeles, CA 90095, USA
Mol Ecol 15:1733-41. 2006.... - Sea ice occurrence predicts genetic isolation in the Arctic foxEli Geffen
Department of Zoology Tel Aviv University, 69978 Tel Aviv, Israel
Mol Ecol 16:4241-55. 2007..In addition, our analysis identified the Commander and Pribilof Islands Arctic populations as genetically unique suggesting they deserve special attention from a conservation perspective... - Differentiation of tundra/taiga and boreal coniferous forest wolves: genetics, coat colour and association with migratory caribouMarco Musiani
Faculty of Environmental Design, University of Calgary, Calgary, AB, Canada T2N 1 N4
Mol Ecol 16:4149-70. 2007..The presence of a distinct wolf ecotype in the tundra of North America highlights the need to preserve migratory populations... - A single IGF1 allele is a major determinant of small size in dogsNathan B Sutter
National Human Genome Research Institute, Building 50, Room 5349, 50 South Drive MSC 8000, Bethesda, MD 20892 8000, USA
Science 316:112-5. 2007..A single IGF1 single-nucleotide polymorphism haplotype is common to all small breeds and nearly absent from giant breeds, suggesting that the same causal sequence variant is a major contributor to body size in all small dogs... - Genome sequence, comparative analysis and haplotype structure of the domestic dogKerstin Lindblad-Toh
Broad Institute of Harvard and MIT, 320 Charles Street, Cambridge, Massachusetts 02141, USA
Nature 438:803-19. 2005..The current SNP map now makes it possible for genome-wide association studies to identify genes responsible for diseases and traits, with important consequences for human and companion animal health... - The canine genomeElaine A Ostrander
Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Genome Res 15:1706-16. 2005..We suggest that given these resources and the unique characteristics of breeds, that the dog is a uniquely valuable resource for studying the genetic basis of complex traits... - Microsatellite DNA analysis shows that greater sage grouse leks are not kin groupsRobert M Gibson
School of Biological Sciences, University of Nebraska Lincoln, NE 68588 0118, USA
Mol Ecol 14:4453-9. 2005..Together with other recent studies, they also raise the question of why kin selection apparently promotes social courtship in some lekking species, but not in others... - Climate and habitat barriers to dispersal in the highly mobile grey wolfEli Geffen
Institute for Nature Conservation Research Tel Aviv University Tel Aviv 69978 Israel
Mol Ecol 13:2481-90. 2004..We suggest two possible mechanisms by which environmental conditions may influence the dispersal decisions made by wolves...