K L Watterberg
Affiliation: University of New Mexico
Watterberg K. Evidence-based neonatal pharmacotherapy: postnatal corticosteroids. Clin Perinatol. 2012;39:47-59 pubmed publisher
..Hydrocortisone therapy is increasingly used to treat hypotension in critically ill newborns; however, the outcomes of this therapy must be evaluated in randomized trials. ..
Watterberg K, Hintz S, Do B, Vohr B, Lowe J, Newman J, et al
. Adrenal function links to early postnatal growth and blood pressure at age 6 in children born extremely preterm. Pediatr Res. 2018;: pubmed publisher
..Blunted morning cortisol may reflect NICU stress, as seen after other adverse childhood experiences (ACEs). ..
Watterberg K, Gerdes J, Cook K. Impaired glucocorticoid synthesis in premature infants developing chronic lung disease. Pediatr Res. 2001;50:190-5 pubmed
..These data support the hypothesis that these immature infants have a decreased capacity to synthesize cortisol, which may lead to a relative adrenal insufficiency in the face of significant illness. ..
Watterberg K, Shaffer M, Garland J, Thilo E, Mammel M, Couser R, et al
. Effect of dose on response to adrenocorticotropin in extremely low birth weight infants. J Clin Endocrinol Metab. 2005;90:6380-5 pubmed
..A cosyntropin dose of 0.1 microg/kg did not differentiate between groups of infants with clinical conditions that affect response. We recommend 1.0 microg/kg cosyntropin to test adrenal function in these infants. ..
Watterberg K, Shaffer M, Mishefske M, Leach C, Mammel M, Couser R, et al
. Growth and neurodevelopmental outcomes after early low-dose hydrocortisone treatment in extremely low birth weight infants. Pediatrics. 2007;120:40-8 pubmed
..Together with the short-term benefit previously reported, these data support additional studies of hydrocortisone treatment of adrenal insufficiency in extremely premature infants. ..