W S Watkins

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. pmc Genetic analysis of ancestry, admixture and selection in Bolivian and Totonac populations of the New World
    W Scott Watkins
    Department of Human Genetics, Eccles Institute of Human Genetics, University of Utah, 15 N 2030 E RM 2100, Salt Lake City, UT 84112, USA
    BMC Genet 13:39. 2012
  2. pmc Genetic variation in South Indian castes: evidence from Y-chromosome, mitochondrial, and autosomal polymorphisms
    W S Watkins
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    BMC Genet 9:86. 2008
  3. ncbi request reprint Diversity and divergence among the tribal populations of India
    W S Watkins
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    Ann Hum Genet 69:680-92. 2005
  4. pmc The distribution of human genetic diversity: a comparison of mitochondrial, autosomal, and Y-chromosome data
    L B Jorde
    Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, UT, 84112, USA
    Am J Hum Genet 66:979-88. 2000
  5. ncbi request reprint Multiple origins of the mtDNA 9-bp deletion in populations of South India
    W S Watkins
    Department of Human Genetics, University of Utah, Salt Lake City 84112 0533, USA
    Am J Phys Anthropol 109:147-58. 1999
  6. pmc Genetic evidence on the origins of Indian caste populations
    M Bamshad
    Department of Pediatrics, University of Utah, Salt Lake City, Utah 84112, USA
    Genome Res 11:994-1004. 2001
  7. pmc Genetic similarities within and between human populations
    D J Witherspoon
    Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, Utah 84112, USA
    Genetics 176:351-9. 2007
  8. ncbi request reprint Population genomics: a bridge from evolutionary history to genetic medicine
    L B Jorde
    Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, UT 84112, USA
    Hum Mol Genet 10:2199-207. 2001
  9. ncbi request reprint Human population genetic structure and diversity inferred from polymorphic L1(LINE-1) and Alu insertions
    D J Witherspoon
    Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, UT 84112 5330, USA
    Hum Hered 62:30-46. 2006
  10. pmc DNA sequence variation in a 3.7-kb noncoding sequence 5' of the CYP1A2 gene: implications for human population history and natural selection
    S P Wooding
    Department of Human Genetics, University of Utah, Salt Lake City, UT, 84112, USA
    Am J Hum Genet 71:528-42. 2002

Collaborators

Detail Information

Publications19

  1. pmc Genetic analysis of ancestry, admixture and selection in Bolivian and Totonac populations of the New World
    W Scott Watkins
    Department of Human Genetics, Eccles Institute of Human Genetics, University of Utah, 15 N 2030 E RM 2100, Salt Lake City, UT 84112, USA
    BMC Genet 13:39. 2012
    ....
  2. pmc Genetic variation in South Indian castes: evidence from Y-chromosome, mitochondrial, and autosomal polymorphisms
    W S Watkins
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    BMC Genet 9:86. 2008
    ..An understanding of these influences is increasingly important as gene mapping and case-control studies are initiated in South Indian populations...
  3. ncbi request reprint Diversity and divergence among the tribal populations of India
    W S Watkins
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    Ann Hum Genet 69:680-92. 2005
    ....
  4. pmc The distribution of human genetic diversity: a comparison of mitochondrial, autosomal, and Y-chromosome data
    L B Jorde
    Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, UT, 84112, USA
    Am J Hum Genet 66:979-88. 2000
    ..These results are reassuring in their consistency and offer broad support for an African origin of modern human populations...
  5. ncbi request reprint Multiple origins of the mtDNA 9-bp deletion in populations of South India
    W S Watkins
    Department of Human Genetics, University of Utah, Salt Lake City 84112 0533, USA
    Am J Phys Anthropol 109:147-58. 1999
    ..These results demonstrate varying genetic affinities of different South Indian tribes to continental populations and underscore the complex histories of the tribal populations living in South Asia...
  6. pmc Genetic evidence on the origins of Indian caste populations
    M Bamshad
    Department of Pediatrics, University of Utah, Salt Lake City, Utah 84112, USA
    Genome Res 11:994-1004. 2001
    ..We conclude that Indian castes are most likely to be of proto-Asian origin with West Eurasian admixture resulting in rank-related and sex-specific differences in the genetic affinities of castes to Asians and Europeans...
  7. pmc Genetic similarities within and between human populations
    D J Witherspoon
    Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, Utah 84112, USA
    Genetics 176:351-9. 2007
    ..This provides empirical justification for caution when using population labels in biomedical settings, with broad implications for personalized medicine, pharmacogenetics, and the meaning of race...
  8. ncbi request reprint Population genomics: a bridge from evolutionary history to genetic medicine
    L B Jorde
    Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, UT 84112, USA
    Hum Mol Genet 10:2199-207. 2001
    ..We review some of the general patterns of human genetic variation, and we show how our knowledge of these patterns can aid in the mapping and cloning of disease-causing genes...
  9. ncbi request reprint Human population genetic structure and diversity inferred from polymorphic L1(LINE-1) and Alu insertions
    D J Witherspoon
    Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, UT 84112 5330, USA
    Hum Hered 62:30-46. 2006
    ..L1 elements drive replication of Alu elements, and both have had far-reaching impacts on the human genome. We use L1 and Alu insertion polymorphisms to analyze human population structure...
  10. pmc DNA sequence variation in a 3.7-kb noncoding sequence 5' of the CYP1A2 gene: implications for human population history and natural selection
    S P Wooding
    Department of Human Genetics, University of Utah, Salt Lake City, UT, 84112, USA
    Am J Hum Genet 71:528-42. 2002
    ..90) frequencies in human populations, a trend consistent with the action of positive natural selection. These patterns have a number of implications for disease-association studies in CYP1A2 and other genes...
  11. ncbi request reprint Mitochondrial mismatch analysis is insensitive to the mutational process
    A R Rogers
    Department of Anthropology, University of Utah, Salt Lake City 84112, USA
    Mol Biol Evol 13:895-902. 1996
    ..01. In addition, we evaluate and reject the proposition that mismatch waves are produced by pooling data from several subdivisions of a structured population...
  12. pmc The spectrum of mutations in TBX3: Genotype/Phenotype relationship in ulnar-mammary syndrome
    M Bamshad
    Department of Pediatrics, Eccles Institute of Human Genetics, 15 North 2030 East, Room 2100, University of Utah, Salt Lake City, UT 84112 5330, USA
    Am J Hum Genet 64:1550-62. 1999
    ..We found no obvious phenotypic differences between those who have missense mutations and those who have deletions or frameshifts...
  13. pmc Microsatellite diversity and the demographic history of modern humans
    L B Jorde
    Eccles Institute of Human Genetics, University of Utah Health Sciences Center, Salt Lake City 84112, USA
    Proc Natl Acad Sci U S A 94:3100-3. 1997
    ..A comparison of continental diversity differences in microsatellites and mtDNA sequences suggests earlier demographic expansion of the ancestors of Africans...
  14. pmc A variant of Freeman-Sheldon syndrome maps to 11p15.5-pter
    P A Krakowiak
    Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City 84112, USA
    Am J Hum Genet 60:426-32. 1997
    ..5-6.5-cM region between the marker TH and the telomere. Analysis of additional families improves the LOD score to 6.45 at theta = 0 and suggests linkage homogeneity for DA2B...
  15. ncbi request reprint Mitochondrial DNA variation in Nicobarese Islanders
    B V Prasad
    Department of Anthropology, Andhra University, Visakhapatnam, Andhra Pradesh, India
    Hum Biol 73:715-25. 2001
    ..g., Cambodians). Thus, the dispersal of southern Chinese into mainland Southeast Asia may have included a westward expansion and colonization of the islands of the Andaman Sea...
  16. ncbi request reprint Large-scale analysis of the Alu Ya5 and Yb8 subfamilies and their contribution to human genomic diversity
    M L Carroll
    Departments of Pathology, Genetics Biochemistry and Molecular Biology Stanley S. Scott Cancer Center Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans 70112, USA
    J Mol Biol 311:17-40. 2001
    ..The newly identified Alu insertion polymorphisms will be useful tools for the study of human genomic diversity...
  17. pmc Linkage disequilibrium in the neurofibromatosis 1 (NF1) region: implications for gene mapping
    L B Jorde
    Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City 84112
    Am J Hum Genet 53:1038-50. 1993
    ..These are discussed, and guidelines for linkage disequilibrium studies are suggested...
  18. pmc A gene for distal arthrogryposis type I maps to the pericentromeric region of chromosome 9
    M Bamshad
    Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City 84132 1001
    Am J Hum Genet 55:1153-8. 1994
    ..Analysis of an additional family demonstrated no linkage to the same locus, indicating likely locus heterogeneity. Of the autosomal congenital contracture disorders causing positional foot deformities, this is the first to be mapped...
  19. pmc The exuperantia gene is required for Drosophila spermatogenesis as well as anteroposterior polarity of the developing oocyte, and encodes overlapping sex-specific transcripts
    T Hazelrigg
    Howard Hughes Medical Institute, University of Utah, Salt Lake City 84112
    Genetics 126:607-17. 1990
    ..1 kb in the female. We also show that these two transcripts are limited in expression to the germline. We demonstrate that one allele, exuVL57, is a deletion of about 700 bp which results in a loss of both transcripts...