Marian Waterman

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Physiological β-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma
    Yue Cheng
    Department of Clinical Oncology, Center for Nasopharyngeal Carcinoma Research, University of Hong Kong, L6 02, 21 Sassoon Road, Pokfulam, Hong Kong SAR, China
    BMC Cell Biol 14:44. 2013
  2. pmc A role for YY1 in repression of dominant negative LEF-1 expression in colon cancer
    Noriko N Yokoyama
    Department of Microbiology and Molecular Genetics, University of California, Irvine, Irvine, CA 92697, USA
    Nucleic Acids Res 38:6375-88. 2010
  3. pmc A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer
    R Najdi
    Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697, USA
    Oncogene 28:4133-46. 2009
  4. pmc Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression
    LAURA ARCE
    Department of Microbiology and Molecular Genetics, University of California Irvine, Irvine, CA 92697 4025, USA
    BMC Cancer 9:159. 2009
  5. ncbi request reprint Lymphoid enhancer factor/T cell factor expression in colorectal cancer
    Marian L Waterman
    Department of Microbiology and Molecular Genetics, College of Medicine, University of California, Irvine, USA
    Cancer Metastasis Rev 23:41-52. 2004
  6. pmc Wnt activation and alternative promoter repression of LEF1 in colon cancer
    Tony W H Li
    Department of Microbiology and Molecular Genetics, Rm B240, Medical Sciences I, University of California, Irvine, Irvine, CA 92697 4025, USA
    Mol Cell Biol 26:5284-99. 2006
  7. pmc An internal ribosome entry site mediates translation of lymphoid enhancer factor-1
    Judith Jimenez
    Department of Microbiology and Molecular Genetics, College of Medicine, University of California, Irvine, CA 92697 4025, USA
    RNA 11:1385-99. 2005
  8. pmc A unique DNA binding domain converts T-cell factors into strong Wnt effectors
    Fawzia A Atcha
    Department of Microbiology and Molecular Genetics, University of California, Irvine, Irvine, CA 92697, USA
    Mol Cell Biol 27:8352-63. 2007
  9. ncbi request reprint IRES-mediated pathways to polysomes: nuclear versus cytoplasmic routes
    Bert L Semler
    Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA 92697, USA
    Trends Microbiol 16:1-5. 2008
  10. ncbi request reprint A new beta-catenin-dependent activation domain in T cell factor
    Fawzia A Atcha
    Microbiology and Molecular Genetics Department, School of Medicine, University of California, Irvine, CA 92697 4025, USA
    J Biol Chem 278:16169-75. 2003

Collaborators

  • BERT SEMLER
  • STEVEN MONROE LIPKIN
  • Robert Andrew Edwards
  • LAURA ARCE
  • Noriko N Yokoyama
  • Fawzia A Atcha
  • Tony W H Li
  • Nate P Hoverter
  • Yue Cheng
  • Shaheen S Sikandar
  • Kira T Pate
  • Steve P Crampton
  • R Najdi
  • Min Yang
  • Beibei Wu
  • Ju Hui T Ting
  • Judith Jimenez
  • Jesus E Munguia
  • Baoan Li
  • Josephine Mun Yee Ko
  • Paulisally Hau Yi Lo
  • Maria Li Lung
  • Pui Man Chiu
  • Yee Peng Phoon
  • Arthur Kwok Leung Cheung
  • Scott Anderson
  • Diana Dizon
  • Stephanie Sprowl
  • Christopher C W Hughes
  • Edward J Park
  • Candice Solomon
  • H Theisen
  • Jai Hyun Kim
  • A Syed
  • F Atcha
  • J L Marsh
  • A V Nguyen
  • J Ht Ting
  • M Martinez
  • R F Holcombe
  • Rainer K Brachmann
  • Harry J Mangalam
  • J Lawrence Marsh
  • Adeela Syed
  • Alla Bernstein
  • Marc van de Wetering
  • Gwendolyn M Jang
  • Karine Hovanes
  • Magid Fallahi
  • Mahalakshmi Nair
  • Anthony P Mahowald
  • Qian Dai
  • Douglas R Mackay
  • Christopher P Schonbaum
  • Xing Dai
  • Judith Fantes
  • Elaine Fuchs

Detail Information

Publications15

  1. pmc Physiological β-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma
    Yue Cheng
    Department of Clinical Oncology, Center for Nasopharyngeal Carcinoma Research, University of Hong Kong, L6 02, 21 Sassoon Road, Pokfulam, Hong Kong SAR, China
    BMC Cell Biol 14:44. 2013
    ....
  2. pmc A role for YY1 in repression of dominant negative LEF-1 expression in colon cancer
    Noriko N Yokoyama
    Department of Microbiology and Molecular Genetics, University of California, Irvine, Irvine, CA 92697, USA
    Nucleic Acids Res 38:6375-88. 2010
    ..We also show that induced expression of dnLEF-1 in colon cancer cells slows their rate of proliferation. We propose that YY1 plays an important role in preventing dnLEF-1 expression and growth inhibition in colon cancer...
  3. pmc A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer
    R Najdi
    Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697, USA
    Oncogene 28:4133-46. 2009
    ..We propose that dnTCF-1 provides homeostatic regulation of Wnt signaling and growth in normal colon, and the alterations in nuclear export and promoter usage contribute to aberrant Wnt activity in colon cancer...
  4. pmc Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression
    LAURA ARCE
    Department of Microbiology and Molecular Genetics, University of California Irvine, Irvine, CA 92697 4025, USA
    BMC Cancer 9:159. 2009
    ..The molecular events involved in this competitive interaction are not defined and the actions of Groucho/TLEs within the context of Wnt-linked cancer are unknown...
  5. ncbi request reprint Lymphoid enhancer factor/T cell factor expression in colorectal cancer
    Marian L Waterman
    Department of Microbiology and Molecular Genetics, College of Medicine, University of California, Irvine, USA
    Cancer Metastasis Rev 23:41-52. 2004
    ..While the underlying mechanism for a change in the LEF/TCF isoform expression is not yet known, recent evidence implicates the Wnt signaling pathway itself as a potential modulator...
  6. pmc Wnt activation and alternative promoter repression of LEF1 in colon cancer
    Tony W H Li
    Department of Microbiology and Molecular Genetics, Rm B240, Medical Sciences I, University of California, Irvine, Irvine, CA 92697 4025, USA
    Mol Cell Biol 26:5284-99. 2006
    ..We conclude that the biological outcome of aberrant LEF1 activation in colon cancer is directed by differential promoter activation and repression...
  7. pmc An internal ribosome entry site mediates translation of lymphoid enhancer factor-1
    Judith Jimenez
    Department of Microbiology and Molecular Genetics, College of Medicine, University of California, Irvine, CA 92697 4025, USA
    RNA 11:1385-99. 2005
    ....
  8. pmc A unique DNA binding domain converts T-cell factors into strong Wnt effectors
    Fawzia A Atcha
    Department of Microbiology and Molecular Genetics, University of California, Irvine, Irvine, CA 92697, USA
    Mol Cell Biol 27:8352-63. 2007
    ..Thus, E-tail isoforms of TCFs utilize two DNA binding activities to access a subset of Wnt targets important for cell growth...
  9. ncbi request reprint IRES-mediated pathways to polysomes: nuclear versus cytoplasmic routes
    Bert L Semler
    Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA 92697, USA
    Trends Microbiol 16:1-5. 2008
    ....
  10. ncbi request reprint A new beta-catenin-dependent activation domain in T cell factor
    Fawzia A Atcha
    Microbiology and Molecular Genetics Department, School of Medicine, University of California, Irvine, CA 92697 4025, USA
    J Biol Chem 278:16169-75. 2003
    ..This study thus identifies a new and unique set of motifs used by the Wnt pathway for target gene regulation...
  11. pmc The LEF1/beta -catenin complex activates movo1, a mouse homolog of Drosophila ovo required for epidermal appendage differentiation
    Baoan Li
    Department of Biological Chemistry, University of California, Irvine, CA 92697, USA
    Proc Natl Acad Sci U S A 99:6064-9. 2002
    ....
  12. pmc Integration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2
    Steve P Crampton
    Department of Molecular Biology and Biochemistry, UCI Institute for Immunology, University of California Irvine, Irvine, California, USA
    PLoS ONE 4:e7841. 2009
    ..Both rac1 and c-jun have recently been implicated in wnt signaling, however their upstream activators have not been identified...
  13. ncbi request reprint hADA2a and hADA3 are required for acetylation, transcriptional activity and proliferative effects of beta-catenin
    Min Yang
    Department of Medicine, University of California, Irvine, California, USA
    Cancer Biol Ther 7:120-8. 2008
    ..Our studies identify hADA2a and hADA3 as crucial cofactors of beta-catenin that are likely involved in the assembly of transactivation-competent beta-catenin complexes at Wnt target genes...
  14. ncbi request reprint A Wnt-fall for gene regulation: repression
    Nate P Hoverter
    Department of Microbiology and Molecular Genetics, University of California, Irvine, Irvine, CA 92697, USA
    Sci Signal 1:pe43. 2008
    ..A recent study uncovered a new mode of repression of Wnt target genes in which recognition of a novel DNA element by TCF specifies that beta-catenin acts as a transcriptional repressor...
  15. pmc NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer
    Shaheen S Sikandar
    Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, USA
    Cancer Res 70:1469-78. 2010
    ..Our findings describe a novel human cell system to study NOTCH signaling in CRC tumor initiation and suggest that inhibition of NOTCH signaling may improve CRC chemoprevention and chemotherapy...