C M Waterman-Storer

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cells
    C M Waterman-Storer
    Department of Biology, University of North Carolina, Chapel Hill 27599 3280, USA
    Curr Biol 8:1227-30. 1998
  2. ncbi Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts
    C M Waterman-Storer
    Department of Biology, University of North Carolina, Chapel Hill 27599, USA
    Nat Cell Biol 1:45-50. 1999
  3. ncbi Microtubule dynamics: treadmilling comes around again
    C M Waterman-Storer
    Department of Biology, CB 3280, 607 Fordham Hall, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Curr Biol 7:R369-72. 1997
  4. ncbi Actomyosin-based retrograde flow of microtubules in the lamella of migrating epithelial cells influences microtubule dynamic instability and turnover and is associated with microtubule breakage and treadmilling
    C M Waterman-Storer
    Department of Biology, 607 Fordham Hall, University of North Carolina, Chapel Hill, North Carolina 27599 3280, USA
    J Cell Biol 139:417-34. 1997
  5. ncbi The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport
    C M Waterman-Storer
    Department of Animal Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 94:12180-5. 1997
  6. ncbi How microtubules get fluorescent speckles
    C M Waterman-Storer
    Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Biophys J 75:2059-69. 1998
  7. ncbi Positive feedback interactions between microtubule and actin dynamics during cell motility
    C M Waterman-Storer
    Department of Biology 607 Fordham Hall University of North Carolina Chapel Hill NC 27599 3280 USA
    Curr Opin Cell Biol 11:61-7. 1999
  8. ncbi Microtubule/organelle motility assays
    C M Waterman-Storer
    University of North Carolina, Chapel Hill, North Carolina, USA
    Curr Protoc Cell Biol . 2001
  9. ncbi The product of the Drosophila gene, Glued, is the functional homologue of the p150Glued component of the vertebrate dynactin complex
    C M Waterman-Storer
    Department of Animal Biology, University of Pennsylvania School of Veterinary Medicine, Philadelphia 19104 6046, USA
    J Biol Chem 271:1153-9. 1996
  10. ncbi Rapid dynamics of the microtubule binding of ensconsin in vivo
    J C Bulinski
    Department of Biological Sciences, Columbia University, College of Physicians and Surgeons, 630 W 168th St, Rm BB1213, New York, NY 10032 3702, USA
    J Cell Sci 114:3885-97. 2001

Detail Information

Publications13

  1. ncbi Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cells
    C M Waterman-Storer
    Department of Biology, University of North Carolina, Chapel Hill 27599 3280, USA
    Curr Biol 8:1227-30. 1998
    ..Our initial applications include the measurement of microtubule movements in mitotic spindles and actin retrograde flow in migrating cells...
  2. ncbi Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts
    C M Waterman-Storer
    Department of Biology, University of North Carolina, Chapel Hill 27599, USA
    Nat Cell Biol 1:45-50. 1999
    ..We suggest that the growth phase of microtubule dynamic instability at leading-edge lamellipodia locally activates Rac1 to drive actin polymerization and lamellipodial protrusion required for cell migration...
  3. ncbi Microtubule dynamics: treadmilling comes around again
    C M Waterman-Storer
    Department of Biology, CB 3280, 607 Fordham Hall, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Curr Biol 7:R369-72. 1997
    ....
  4. ncbi Actomyosin-based retrograde flow of microtubules in the lamella of migrating epithelial cells influences microtubule dynamic instability and turnover and is associated with microtubule breakage and treadmilling
    C M Waterman-Storer
    Department of Biology, 607 Fordham Hall, University of North Carolina, Chapel Hill, North Carolina 27599 3280, USA
    J Cell Biol 139:417-34. 1997
    ..We propose that actomyosin-based retrograde flow of MTs causes MT breakage, forming quasi-stable noncentrosomal MTs whose turnover is regulated primarily at their minus ends...
  5. ncbi The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport
    C M Waterman-Storer
    Department of Animal Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 94:12180-5. 1997
    ....
  6. ncbi How microtubules get fluorescent speckles
    C M Waterman-Storer
    Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Biophys J 75:2059-69. 1998
    ..Speckle patterns can provide fiduciary marks in the microtubule lattice for motility studies or can be used to determine the fraction of labeled tubulin microinjected into living cells...
  7. ncbi Positive feedback interactions between microtubule and actin dynamics during cell motility
    C M Waterman-Storer
    Department of Biology 607 Fordham Hall University of North Carolina Chapel Hill NC 27599 3280 USA
    Curr Opin Cell Biol 11:61-7. 1999
    ..Thus, an actin-dependent gradient in microtubule dynamic-instability parameters in cells may feed back through the activation of specific signalling pathways to perpetuate the polarized actin-assembly dynamics required for cell motility...
  8. ncbi Microtubule/organelle motility assays
    C M Waterman-Storer
    University of North Carolina, Chapel Hill, North Carolina, USA
    Curr Protoc Cell Biol . 2001
    ....
  9. ncbi The product of the Drosophila gene, Glued, is the functional homologue of the p150Glued component of the vertebrate dynactin complex
    C M Waterman-Storer
    Department of Animal Biology, University of Pennsylvania School of Veterinary Medicine, Philadelphia 19104 6046, USA
    J Biol Chem 271:1153-9. 1996
    ....
  10. ncbi Rapid dynamics of the microtubule binding of ensconsin in vivo
    J C Bulinski
    Department of Biological Sciences, Columbia University, College of Physicians and Surgeons, 630 W 168th St, Rm BB1213, New York, NY 10032 3702, USA
    J Cell Sci 114:3885-97. 2001
    ..Our results show that ensconsin is highly dynamic in its association with microtubules, and its microtubule association can be altered by in vivo phosphorylation events...
  11. ncbi The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)
    C M Waterman-Storer
    Department of Animal Biology, University of Pennsylvania School of Veterinary Medicine, Philadelphia 19104 6046
    Proc Natl Acad Sci U S A 92:1634-8. 1995
    ..These results demonstrate that p150Glued, a protein implicated in cytoplasmic dynein-based microtubule motility, is capable of direct binding to both microtubules and centractin...
  12. ncbi Cell motility: can Rho GTPases and microtubules point the way?
    T Wittmann
    The Scripps Research Institute, Department of Cell Biology, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Cell Sci 114:3795-803. 2001
    ..Thus, microtubules might be part of a positive feedback mechanism that maintains the stable polarization of a directionally migrating cell...
  13. ncbi Recovery, visualization, and analysis of actin and tubulin polymer flow in live cells: a fluorescent speckle microscopy study
    P Vallotton
    BioMicroMetrics Group, Laboratory for Biomechanics, ETH Zurich, 8952 Schlieren, Switzerland
    Biophys J 85:1289-306. 2003
    ..Third, we analyze microtubule poleward flux in mitotic metaphase spindles assembled in Xenopus egg extracts, bringing new insight into the dynamics of microtubule assemblies in this system...