Mineo Watanabe

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. ncbi request reprint Whooping cough due to Bordetella parapertussis: an unresolved problem
    Mineo Watanabe
    University of Cincinnati, Department of Molecular Genetics, Biochemistry and Microbiology, 231 Albert Sabin Way, Cincinnati, OH 45267 0524, USA
    Expert Rev Anti Infect Ther 2:447-54. 2004
  2. ncbi request reprint Acellular pertussis vaccines in Japan: past, present and future
    Mineo Watanabe
    Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, 231 Albert B Sabin Way, Cincinnati, OH 45267 0524, USA
    Expert Rev Vaccines 4:173-84. 2005
  3. pmc Characterization of serological responses to pertussis
    Mineo Watanabe
    Department of Molecular Genetics, Biochemistry, and Microbiology, College of Medicine, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267 0524, USA
    Clin Vaccine Immunol 13:341-8. 2006
  4. ncbi request reprint Evaluation of efficacy in terms of antibody levels and cell-mediated immunity of acellular pertussis vaccines in a murine model of respiratory infection
    Mineo Watanabe
    Department of Microbiology and Biologics, Daiichi College of Pharmaceutical Sciences, 22 1 Tamagawa cho, Minami Ku, Fukuoka 815 8511, Japan
    FEMS Immunol Med Microbiol 33:219-25. 2002
  5. doi request reprint The Bordetella type III secretion system: its application to vaccine development
    Akio Abe
    Laboratory of Bacterial Infection, Kitasato Institute for Life Sciences, Kitasato University, and The Kitasato Institute, Tokyo, Japan
    Microbiol Immunol 52:128-33. 2008
  6. ncbi request reprint Efficacy of pertussis components in an acellular vaccine, as assessed in a murine model of respiratory infection and a murine intracerebral challenge model
    Mineo Watanabe
    Research Center for Biologicals, The Kitasato Institute, 6 111 Arai, Kitamoto, 364 0026, Saitama, Japan
    Vaccine 20:1429-34. 2002
  7. pmc Role of systemic and mucosal immune responses in reciprocal protection against Bordetella pertussis and Bordetella parapertussis in a murine model of respiratory infection
    Mineo Watanabe
    Department of Microbiology and Biologicals, Daiichi College of Pharmaceutical Sciences, Fukuoka 815 8511, Japan
    Infect Immun 71:733-8. 2003
  8. ncbi request reprint Lipooligosaccharide from Bordetella pertussis induces mature human monocyte-derived dendritic cells and drives a Th2 biased response
    Giorgio Fedele
    Department of Infectious, Parasitic and Immune Mediated Diseases, Anti infectious Immunity Unit, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Microbes Infect 9:855-63. 2007
  9. ncbi request reprint Lipopolysaccharides from Bordetella pertussis and Bordetella parapertussis differently modulate human dendritic cell functions resulting in divergent prevalence of Th17-polarized responses
    Giorgio Fedele
    Department of Infectious, Parasitic and Immune Mediated Diseases, Anti infectious Immunity Unit, Istituto Superiore di Sanita, Rome, Italy
    J Immunol 181:208-16. 2008

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Whooping cough due to Bordetella parapertussis: an unresolved problem
    Mineo Watanabe
    University of Cincinnati, Department of Molecular Genetics, Biochemistry and Microbiology, 231 Albert Sabin Way, Cincinnati, OH 45267 0524, USA
    Expert Rev Anti Infect Ther 2:447-54. 2004
    ..In this review, the relevant studies of B. parapertussis are summarized and it is demonstrated that it is now necessary to pay greater attention to infections by this bacterium...
  2. ncbi request reprint Acellular pertussis vaccines in Japan: past, present and future
    Mineo Watanabe
    Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, 231 Albert B Sabin Way, Cincinnati, OH 45267 0524, USA
    Expert Rev Vaccines 4:173-84. 2005
    ..This review describes the major events associated with the Japanese vaccination program. The Japanese experience should be valuable to other countries that are considering the development and use of such vaccines...
  3. pmc Characterization of serological responses to pertussis
    Mineo Watanabe
    Department of Molecular Genetics, Biochemistry, and Microbiology, College of Medicine, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267 0524, USA
    Clin Vaccine Immunol 13:341-8. 2006
    ..The use of a combination of multiple ELISA targets improved the sensitivity of the assay for serological diagnosis. Elevated IgG and IgA antibody titers persisted for more than a year in the individuals with culture-confirmed pertussis...
  4. ncbi request reprint Evaluation of efficacy in terms of antibody levels and cell-mediated immunity of acellular pertussis vaccines in a murine model of respiratory infection
    Mineo Watanabe
    Department of Microbiology and Biologics, Daiichi College of Pharmaceutical Sciences, 22 1 Tamagawa cho, Minami Ku, Fukuoka 815 8511, Japan
    FEMS Immunol Med Microbiol 33:219-25. 2002
    ..However, antibody levels and cell-mediated immune responses were not correlated with the protective effects of the vaccines after aerosol challenge and after i.c. challenge...
  5. doi request reprint The Bordetella type III secretion system: its application to vaccine development
    Akio Abe
    Laboratory of Bacterial Infection, Kitasato Institute for Life Sciences, Kitasato University, and The Kitasato Institute, Tokyo, Japan
    Microbiol Immunol 52:128-33. 2008
    ..One candidate for protective antigens is the type III secretion system and its secreted proteins...
  6. ncbi request reprint Efficacy of pertussis components in an acellular vaccine, as assessed in a murine model of respiratory infection and a murine intracerebral challenge model
    Mineo Watanabe
    Research Center for Biologicals, The Kitasato Institute, 6 111 Arai, Kitamoto, 364 0026, Saitama, Japan
    Vaccine 20:1429-34. 2002
    ..Ratios of FHA:PT of 1:11 or 2:10 (w/w) might be suitable for future formulations...
  7. pmc Role of systemic and mucosal immune responses in reciprocal protection against Bordetella pertussis and Bordetella parapertussis in a murine model of respiratory infection
    Mineo Watanabe
    Department of Microbiology and Biologicals, Daiichi College of Pharmaceutical Sciences, Fukuoka 815 8511, Japan
    Infect Immun 71:733-8. 2003
    ..parapertussis on infected mice. The data suggest that mucosal immunity including secreted immunoglobulin A in the lungs might play an important role in reciprocal protective immunity in this murine model of respiratory infection...
  8. ncbi request reprint Lipooligosaccharide from Bordetella pertussis induces mature human monocyte-derived dendritic cells and drives a Th2 biased response
    Giorgio Fedele
    Department of Infectious, Parasitic and Immune Mediated Diseases, Anti infectious Immunity Unit, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Microbes Infect 9:855-63. 2007
    ..Considering these properties, the use of LOS in the formulation of acellular pertussis vaccines to potentiate protective and adjuvant capacity should be taken into consideration...
  9. ncbi request reprint Lipopolysaccharides from Bordetella pertussis and Bordetella parapertussis differently modulate human dendritic cell functions resulting in divergent prevalence of Th17-polarized responses
    Giorgio Fedele
    Department of Infectious, Parasitic and Immune Mediated Diseases, Anti infectious Immunity Unit, Istituto Superiore di Sanita, Rome, Italy
    J Immunol 181:208-16. 2008
    ..Overall, the data observed reflect the different structure of the two LPS and the higher Th17 response induced by B. pertussis LOS may contribute to the severity of pertussis in humans...