Christina L Wassel

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Associations of pericardial and intrathoracic fat with coronary calcium presence and progression in a multiethnic study
    Christina L Wassel
    Division of Preventive Medicine, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California, USA
    Obesity (Silver Spring) 21:1704-12. 2013
  2. pmc Kidney function and multiple hemostatic markers: cross sectional associations in the multi-ethnic study of atherosclerosis
    Ruth Dubin
    Department of Medicine, Division Nephrology, University of California San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0532, USA
    BMC Nephrol 12:3. 2011
  3. pmc Genetic ancestry is associated with subclinical cardiovascular disease in African-Americans and Hispanics from the multi-ethnic study of atherosclerosis
    Christina L Wassel
    Department of Family and Prevention Medicine, University of California, San Diego, CA 92093 0965, USA
    Circ Cardiovasc Genet 2:629-36. 2009
  4. pmc Associations of SNPs in ADIPOQ and subclinical cardiovascular disease in the multi-ethnic study of atherosclerosis (MESA)
    Christina L Wassel
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California, USA
    Obesity (Silver Spring) 19:840-7. 2011
  5. doi Variants in the adiponectin gene and serum adiponectin: the Coronary Artery Development in Young Adults (CARDIA) Study
    Christina L Wassel
    Department of Family and Preventive Medicine, University of California San Diego, La Jolla, California, USA
    Obesity (Silver Spring) 18:2333-8. 2010
  6. doi The epidemiology of subclavian artery calcification
    Anand Prasad
    Department of Medicine, Division of Cardiology, University of California, San Diego, Calif, USA
    J Vasc Surg 54:1408-13. 2011
  7. doi Genetic ancestry and lower extremity peripheral artery disease in the Multi-Ethnic Study of Atherosclerosis
    Matthew A Allison
    Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA 92093 0965, USA
    Vasc Med 15:351-9. 2010
  8. doi Calcium density of coronary artery plaque and risk of incident cardiovascular events
    Michael H Criqui
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla2Department of Medicine, University of California, San Diego, La Jolla
    JAMA 311:271-8. 2014
  9. doi The association of bone density and calcified atherosclerosis is stronger in women without dyslipidemia: the multi-ethnic study of atherosclerosis
    Nicole E Jensky
    Division of Preventive Medicine, Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA, USA
    J Bone Miner Res 26:2702-9. 2011
  10. doi Biomarkers in peripheral arterial disease patients and near- and longer-term mortality
    Michael H Criqui
    University of California San Diego School of Medicine, La Jolla, CA 92093 0607, USA
    J Vasc Surg 52:85-90. 2010

Detail Information

Publications35

  1. pmc Associations of pericardial and intrathoracic fat with coronary calcium presence and progression in a multiethnic study
    Christina L Wassel
    Division of Preventive Medicine, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California, USA
    Obesity (Silver Spring) 21:1704-12. 2013
    ..Ectopic adipose depots may provide a more refined representation of the role of adiposity in CVD. Thus, the association of pericardial and intra-thoracic fat with coronary artery calcium (CAC) was examined...
  2. pmc Kidney function and multiple hemostatic markers: cross sectional associations in the multi-ethnic study of atherosclerosis
    Ruth Dubin
    Department of Medicine, Division Nephrology, University of California San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0532, USA
    BMC Nephrol 12:3. 2011
    ..73 m2, chronic kidney disease (CKD) is strongly and independently associated with cardiovascular and overall mortality. We hypothesized that reduced kidney function would be characterized by abnormalities of hemostasis...
  3. pmc Genetic ancestry is associated with subclinical cardiovascular disease in African-Americans and Hispanics from the multi-ethnic study of atherosclerosis
    Christina L Wassel
    Department of Family and Prevention Medicine, University of California, San Diego, CA 92093 0965, USA
    Circ Cardiovasc Genet 2:629-36. 2009
    ..In the United States, there has been a significant intermixing among racial/ethnic groups creating admixed populations. Very little research exists on the relationship of genetic ancestry and subclinical CVD measures...
  4. pmc Associations of SNPs in ADIPOQ and subclinical cardiovascular disease in the multi-ethnic study of atherosclerosis (MESA)
    Christina L Wassel
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California, USA
    Obesity (Silver Spring) 19:840-7. 2011
    ..There appears to be an association between ADIPOQ SNPs and subclinical CVD in African Americans and Hispanics. Replication as well as assessment of other ADIPOQ SNPs is warranted...
  5. doi Variants in the adiponectin gene and serum adiponectin: the Coronary Artery Development in Young Adults (CARDIA) Study
    Christina L Wassel
    Department of Family and Preventive Medicine, University of California San Diego, La Jolla, California, USA
    Obesity (Silver Spring) 18:2333-8. 2010
    ..0029) and between rs9882505 and smoking (P = 0.001) in whites. Many ADIPOQ SNPs have not yet been examined, and additional studies are needed to determine whether these may be functional variants...
  6. doi The epidemiology of subclavian artery calcification
    Anand Prasad
    Department of Medicine, Division of Cardiology, University of California, San Diego, Calif, USA
    J Vasc Surg 54:1408-13. 2011
    ..The purpose of the present study was to determine the prevalence and risk factor associations for subclavian artery calcification...
  7. doi Genetic ancestry and lower extremity peripheral artery disease in the Multi-Ethnic Study of Atherosclerosis
    Matthew A Allison
    Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA 92093 0965, USA
    Vasc Med 15:351-9. 2010
    ....
  8. doi Calcium density of coronary artery plaque and risk of incident cardiovascular events
    Michael H Criqui
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla2Department of Medicine, University of California, San Diego, La Jolla
    JAMA 311:271-8. 2014
    ..The standard CAC score is the Agatston, which is weighted upward for greater calcium density. However, some data suggest increased plaque calcium density may be protective for CVD...
  9. doi The association of bone density and calcified atherosclerosis is stronger in women without dyslipidemia: the multi-ethnic study of atherosclerosis
    Nicole E Jensky
    Division of Preventive Medicine, Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA, USA
    J Bone Miner Res 26:2702-9. 2011
    ..54). The inverse association of BMD with CAC is stronger in women without dyslipidemia. These data argue against the hypothesis that dyslipidemia is the key factor responsible for the inverse association of BMD with atherosclerosis...
  10. doi Biomarkers in peripheral arterial disease patients and near- and longer-term mortality
    Michael H Criqui
    University of California San Diego School of Medicine, La Jolla, CA 92093 0607, USA
    J Vasc Surg 52:85-90. 2010
    ..Our objective was to determine in patients with PAD whether novel biomarkers improve prediction of CVD mortality and total mortality...
  11. pmc Associations of estradiol and testosterone with serum phosphorus in older men: the Osteoporotic Fractures in Men study
    Jerry Meng
    Division of Nephrology, Department of Medicine, University of California San Diego, San Diego, California, USA
    Kidney Int 78:415-22. 2010
    ..The mechanism responsible for the association of testosterone with serum phosphorus remains to be determined...
  12. pmc Family history of peripheral artery disease is associated with prevalence and severity of peripheral artery disease: the San Diego population study
    Christina L Wassel
    Division of Preventive Medicine, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California 92093 0965, USA
    J Am Coll Cardiol 58:1386-92. 2011
    ..The purpose of this study was to determine the association of family history of peripheral artery disease (PAD) with PAD prevalence and severity...
  13. pmc Sex-specific association of fetuin-A with type 2 diabetes in older community-dwelling adults: the Rancho Bernardo study
    Gail A Laughlin
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California San Diego, La Jolla, California, USA
    Diabetes Care 36:1994-2000. 2013
    ..This study evaluated the sex-specific association of plasma fetuin-A levels with prevalent and incident type 2 diabetes in community-dwelling older adults...
  14. doi The association between abdominal body composition and vascular calcification
    Nicole E Jensky
    Department of Family and Preventive Medicine, University of California San Diego, La Jolla, California, USA
    Obesity (Silver Spring) 19:2418-24. 2011
    ..Also, the association between lean muscle and vascular calcification was independent of visceral adipose tissue. In conclusion, adipose tissue was positively and lean body mass inversely associated with prevalent aortic calcification...
  15. pmc Association of self-reported race/ethnicity and genetic ancestry with arterial elasticity: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Christina L Wassel
    University of California San Diego, La Jolla, CA, USA
    J Am Soc Hypertens 5:463-72. 2011
    ..Among Hispanics, ancestry is strongly associated with SAE. Future studies should consider genetic ancestry when studying hypertension in race/ethnic minorities, particularly among Hispanics...
  16. pmc Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate Gene Association Resource (CARe)
    Christina L Wassel
    University of California, San Diego, CA, USA
    Blood 117:268-75. 2011
    ....
  17. pmc Serum phosphorus levels and the spectrum of ankle-brachial index in older men: the Osteoporotic Fractures in Men (MrOS) study
    Jerry Meng
    Division of Nephrology, Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, California, USA
    Am J Epidemiol 171:909-16. 2010
    ..These associations may explain the link between serum phosphorus levels and CVD events...
  18. pmc F2-isoprostanes and adiposity in older adults
    Alka M Kanaya
    University of California, San Francisco, California, USA
    Obesity (Silver Spring) 19:861-7. 2011
    ..05). In conclusion, F(2)-IPs were associated with measures of total and regional adiposity in women alone and these associations were partially explained by adipocytokines. F(2)-IPs predicted loss of total adiposity over time among women...
  19. doi Comparison of ordinal versus Agatston coronary calcification scoring for cardiovascular disease mortality in community-living individuals
    Katherine J Blair
    University of California, San Diego, School of Medicine, La Jolla, CA, USA
    Int J Cardiovasc Imaging 30:813-8. 2014
    ..57 (1.00-2.46) using the Agatston score. A simple ordinal CAC score is reproducible, strongly correlated with Agatston CAC scores, and provides similar prediction for CVD death in predominantly Caucasian community-living individuals. ..
  20. pmc The association of fetuin-A with cardiovascular disease mortality in older community-dwelling adults: the Rancho Bernardo study
    Gail A Laughlin
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California San Diego, La Jolla, California 92093, USA
    J Am Coll Cardiol 59:1688-96. 2012
    ..The goal of this study was to evaluate the prospective association of fetuin-A levels with cardiovascular disease (CVD) mortality...
  21. pmc The associations of fetuin-A with subclinical cardiovascular disease in community-dwelling persons: the Rancho Bernardo Study
    Joachim H Ix
    Nephrology Section, Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA
    J Am Coll Cardiol 58:2372-9. 2011
    ..The aim of this study was to determine the association of fetuin-A with subclinical cardiovascular disease (CVD) in community-living individuals...
  22. pmc Equations to estimate creatinine excretion rate: the CKD epidemiology collaboration
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, and San Diego VA Healthcare System, 3350 La Jolla Village Drive, Mail Code 111 H, San Diego, CA 92161, USA
    Clin J Am Soc Nephrol 6:184-91. 2011
    ..Creatinine excretion rate (CER) indicates timed urine collection accuracy. Although equations to estimate CER exist, their bias and precision are untested and none simultaneously include age, sex, race, and weight...
  23. pmc Fetuin-A and change in body composition in older persons
    Joachim H Ix
    Division of Nephrology, Department of Medicine, and Division of Preventive Medicine, University of California San Diego, Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA
    J Clin Endocrinol Metab 94:4492-8. 2009
    ..Whether higher fetuin-A concentrations are associated with accumulation of adiposity over time is unknown...
  24. doi Associations of physical activity and sedentary behavior with regional fat deposition
    Britta A Larsen
    1Department of Family and Preventive Medicine, University of California, San Diego, San Diego, CA and 2Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA
    Med Sci Sports Exerc 46:520-8. 2014
    ..The purpose of this study was to explore associations of self-reported leisure PA and sitting time with regional fat depositions and abdominal muscle among community-dwelling older adults...
  25. doi β(1)-adrenergic receptor polymorphisms and response to β-blockade in the African-American study of kidney disease and hypertension (AASK)
    Jason Lee
    Department of Medicine, University of California, San Diego UCSD, La Jolla, California, USA
    Am J Hypertens 24:694-700. 2011
    ..This study focuses on the relationship between β(1)-adrenergic receptor (ADRB1) polymorphisms and blood pressure response to the β-blocker metoprolol among African Americans with early hypertensive nephrosclerosis...
  26. pmc Imputation of coding variants in African Americans: better performance using data from the exome sequencing project
    Qing Duan
    Department of Genetics and Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599, USA, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA, Department of Biostatistics, University of North Carolina, Chapel Hill, NC 27599, USA, Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA, Renaissance Computing Institute, University of North Carolina, Chapel Hill, NC 27599, USA, Department of Statistics and Department of Genetics, Rutgers University, Piscataway, NJ 08854, USA, Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599, USA, Department of Epidemiology, University of Washington, Seattle, WA 98195, USA, Division of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA, Department of Epidemiology and Medicine, University of Iowa, Iowa City, IA 52242, Division of Cardiology, George Washington University School of Medicine and Health Sciences, Washington, DC 20037, USA, Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, France
    Bioinformatics 29:2744-9. 2013
    ..We recommend using haplotypes from Exome Sequencing Project alone or concatenation of the two panels over quality score-based post-imputation selection or IMPUTE2's two-panel combination...
  27. pmc Renal artery calcification and mortality among clinically asymptomatic adults
    Dena E Rifkin
    Division of Preventive Medicine, University of California, San Diego School of Medicine, San Diego, California 92161, USA
    J Am Coll Cardiol 60:1079-85. 2012
    ..The goal of this study was to assess the associations between renal artery calcification (RAC) and mortality in a healthy outpatient cohort with no known cardiovascular disease (CVD)...
  28. doi Calcified atherosclerosis in different vascular beds and the risk of mortality
    Matthew A Allison
    Department of Family and Preventive Medicine, University of California San Diego, USA
    Arterioscler Thromb Vasc Biol 32:140-6. 2012
    ..The goal of this study was to determine differences in risks for total and cause-specific mortality related to calcified atherosclerosis in different vascular beds...
  29. pmc Fetuin-A and BMD in older persons: the Health Aging and Body Composition (Health ABC) study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, University of California San Diego, San Diego, California, USA
    J Bone Miner Res 24:514-21. 2009
    ..Future studies should evaluate whether fetuin-A may refine fracture risk assessment in older women...
  30. pmc Fetuin-A and incident diabetes mellitus in older persons
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, and San Diego Veterans Affairs Healthcare System, 3350 La Jolla Village Dr, Mail Code 111 H, San Diego, CA 92161, USA
    JAMA 300:182-8. 2008
    ..In prior cross-sectional studies in humans, higher fetuin-A levels were associated with insulin resistance. However, the longitudinal association of fetuin-A with incident type 2 diabetes mellitus is unknown...
  31. pmc Urinary creatinine excretion rate and mortality in persons with coronary artery disease: the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, and VA San Diego Healthcare System, 3350 La Jolla Village Dr, Mail Code 111 H, San Diego, CA 92161, USA
    Circulation 121:1295-303. 2010
    ..In persons with coronary artery disease, low body mass index is associated with greater mortality; however, it is uncertain whether low muscle mass is a risk factor for mortality in this setting...
  32. pmc Association of circulating C-reactive protein and interleukin-6 with longevity into the 80s and 90s: The Rancho Bernardo Study
    Christina L Wassel
    Division of Preventive Medicine, Department of Family and Preventive Medicine, University of California, San Diego, San Diego, California 92093, USA
    J Clin Endocrinol Metab 95:4748-55. 2010
    ..Few studies have examined whether the inflammatory markers IL-6 and C-reactive protein (CRP) are associated with exceptional longevity...
  33. pmc Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium
    Christina L Wassel
    University of California San Diego, Department of Family and Preventive Medicine, Division of Preventive Medicine, La Jolla, CA, USA
    Atherosclerosis 222:138-47. 2012
    ..We conducted a two stage meta-analysis of ∼50,000 SNPs across ∼2100 candidate genes to identify genetic variants for ABI...
  34. pmc Fibroblast growth factor-23 and early decrements in kidney function: the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, University of California San Diego, San Diego, CA, USA
    Nephrol Dial Transplant 25:993-7. 2010
    ..The threshold of CKD or albuminuria at which FGF-23 begins to change is unknown...
  35. pmc Blood pressure and vascular calcification
    Nicole E Jensky
    Departments of Family and Preventive Medicine, University of California San Diego, La Jolla, Calif 92037, USA
    Hypertension 55:990-7. 2010
    ..Isolated systolic hypertension may be clinically relevant in diagnosing or preventing calcified atherosclerosis...