Research Topics
Species | D G WarnockSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Detail Information
Publications
The epithelial sodium channel in hypertensionD G Warnock
Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35294 0007, USA
Curr Hypertens Rep 1:158-63. 1999..As a result, we now have clearly defined syndromes in which ENaC activity is dysregulated with subsequent development of disorders of systemic blood pressure that can be attributed to a primary renal mechanism...- Aldosterone-related genetic effects in hypertensionD G Warnock
Division of Nephrology, University of Alabama at Birmingham, 1530 3rd Avenue South, THT 647, Birmingham, AL 35294 0007, USA
Curr Hypertens Rep 2:295-301. 2000..Applying these insights to the far more common disorder of low-renin hypertension may shed new light on the underlying pathophysiology of this common form of human hypertension... - Low renin hypertension in the next millenniumD G Warnock
Department of Medicine, University of Alabama at Birmingham, 35294 0007, USA
Semin Nephrol 20:40-6. 2000.... - HypertensionD G Warnock
Department of Medicine, University of Alabama at Birmingham, 35294 0007, USA
Semin Nephrol 19:374-80. 1999.... - Genetic forms of human hypertensionD G Warnock
Departments of Medicine and Physiology and Biophysics, and Nephrology Research and Training Center, University of Alabama at Birmingham, 35294 0007, USA
Curr Opin Nephrol Hypertens 10:493-9. 2001.... - Liddle syndrome: genetics and mechanisms of Na+ channel defectsD G Warnock
Department of Medicine, University of Alabama at Birmingham, UAB Station, 35294 0007, USA
Am J Med Sci 322:302-7. 2001..The focus of the current review is on Liddle syndrome ("pseudoaldosteronism")... - The human angiotensinase C gene (HUMPCP) maps to 11q14 within 700 kb of D11S901: a candidate gene for essential hypertensionB Watson
Department of Medicine, University of Albama School of Medicine, Birmingham 35294-0007, USA
Genomics 44:365-7. 1997 - Genetic association of 11 beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) flanking microsatellites with essential hypertension in blacksB Watson
Division of Nephrology, University of Alabama School of Medicine, Birmingham
Hypertension 28:478-82. 1996..Confirmation of our findings in another independently ascertained group of hypertensive subjects will provide a basis for proceeding with sib-pair linkage analyses... - Disorders of the epithelial Na(+) channel in Liddle's syndrome and autosomal recessive pseudohypoaldosteronism type 1Y S Oh
Department of Medicine, Nephrology Research and Training Center, University of Alabama at Birmingham, 35294, USA
Exp Nephrol 8:320-5. 2000..In this review, our current understanding about ENaC and the pathophysiology of Liddle's syndrome and PHA-1 caused by ENaC mutations will be discussed... - Prevention, protection, and the intrarenal renin-angiotensin systemsD G Warnock
Division of Nephrology, Department of Medicine, Nephrology Research and Training Center, University of Alabama at Birmingham, UAB Station, Birmingham, AL 35294 0006, USA
Semin Nephrol 21:593-602. 2001..Whether or not inhibition of these pathways is involved in the renoprotective effects of ACE inhibitors and angiotensin receptor antagonists is an important issue to be addressed... - Simplified citrate anticoagulation for continuous renal replacement therapyA J Tolwani
Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Alabama 35294 0007, USA
Kidney Int 60:370-4. 2001..However, because of the metabolic complications of trisodium citrate, it is a complicated technique requiring specialized dialysis solutions. We have designed a simplified protocol for citrate regional anticoagulation for CRRT... - Membranous glomerulopathy in an adult patient with X-linked agammaglobulinemia receiving intravenous gammaglobulinL M Endo
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35294 2182, USA
J Investig Allergol Clin Immunol 21:405-9. 2011..Immune complex deposition in the subepithelial zone of glomerular capillaries can lead to membranous glomerulopathy... - Interaction of syntaxins with the amiloride-sensitive epithelial sodium channelS Saxena
Nephrology Research and Training Center, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
J Biol Chem 274:20812-7. 1999.... - Inverse relationship of urinary cyclic GMP to blood pressure reactivity in the CARDIA study: vasodilatory regulation of sympathetic vasoconstriction. Coronary Artery Risk Development in Young AdultsJ H Markovitz
Department of Medicine, University of Alabama at Birmingham, 35205, USA
Psychosom Med 60:319-26. 1998.... - Cloning and functional studies of splice variants of the alpha-subunit of the amiloride-sensitive Na+ channelJ K Tucker
Department of Medicine, University of Alabama, Birmingham 35294, USA
Am J Physiol 274:C1081-9. 1998..These findings indicate that the extracellular domain is important to generate structural and functional diversity of h alpha ENaC and that alternative splicing may play a role in regulating hENaC activity... - Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channelR A Shimkets
Howard Hughes Medical Institute, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, Connecticut 06510
Cell 79:407-14. 1994..These findings demonstrate that Liddle's syndrome is caused by mutations in the beta subunit of the epithelial sodium channel and have implications for the regulation of this epithelial ion channel as well as blood pressure homeostasis...