Research Topics
| Huber R WarnerSummaryAffiliation: University of Minnesota Country: USA Publications
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Detail Information
Publications
Developing a research agenda in biogerontology: basic mechanismsHuber R Warner
College of Biological Sciences, University of Minnesota, St Paul, MN 55108, USA
Sci Aging Knowledge Environ 2005:pe33. 2005....
Research on Hutchinson-Gilford progeria syndromeHuber R Warner
J Gerontol A Biol Sci Med Sci 63:775-6. 2008
Science fact and the SENS agenda. What can we reasonably expect from ageing research?Huber Warner
Buck Institute for Age Research, Novato, CA, USA
EMBO Rep 6:1006-8. 2005
Nuclear architecture and diseaseHuber R Warner
College of Biological Sciences, University of Minnesota, 123 Snyder Hall, 1475 Gortner Ave, St. Paul, MN 55108, USA
J Gerontol A Biol Sci Med Sci 61:461-2. 2006
Scientific and ethical concerns regarding engineering human longevityHuber R Warner
College of Biological Sciences, University of Minnesota, St Paul, Minnesota 55108, USA
Rejuvenation Res 9:440-2; discussion 443-5. 2006....
Is cell death and replacement a factor in aging?Huber R Warner
University of Minnesota, College of Biological Sciences, St Paul, MN 55108, United States
Mech Ageing Dev 128:13-6. 2007....
Time, damage, and aging: what really matters?Huber R Warner
College of Biological Sciences, University of Minnesota, St Paul, Minnesota 55108, USA
Rejuvenation Res 10:373-5. 2007..While this assumption seems quite reasonable, some recent results suggest that this approach is not as straightforward as it might seem...
2006 Kent award lecture: is cell death and replacement a factor in aging?Huber R Warner
College of Biological Sciences, University of Minnesota, St Paul, MN 55108, USA
J Gerontol A Biol Sci Med Sci 62:1228-32. 2007....
Making the political case for biogerontology funding: a view from the trenchesHuber R Warner
College of Biological Sciences, University of Minnesota, St. Paul, Minnesota 55108, USA
Rejuvenation Res 11:485-8. 2008
If you wish to live a long time in good health, choose your parents carefullyHuber R Warner
J Gerontol A Biol Sci Med Sci 62:575-6. 2007
The future of aging therapiesEvan C Hadley
National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA
Cell 120:557-67. 2005....
Longevity genes: from primitive organisms to humansHuber R Warner
Biology of Aging Program, Gateway Building, Room 2C231, National Institute on Aging, Bethesda, MD 20892, USA
Mech Ageing Dev 126:235-42. 2005..How longevity regulation relates to aging per se is less clear, but longevity increases are usually accompanied by extended periods of good health. How these results will translate to primate aging and longevity remains to be shown...
The aging factor in health and disease: the promise of basic research on agingRobert N Butler
International Longevity Center-USA, Alliance for Health and the Future, and Department of Geriatrics, Mount Sinai Medical Center, New York, NY 10028, USA
Aging Clin Exp Res 16:104-11; discussion 111-2. 2004
Subfield history: use of model organisms in the search for human aging genesHuber R Warner
Biology of Aging Program at the National Institute on Aging, Bethesda, MD 20892, USA
Sci Aging Knowledge Environ 2003:RE1. 2003..The ultimate goal of this program is to extend these results to humans to identify the major biological risk factors for age-related decline of function in human physiological systems...
Longevity genes: from primitive organisms to humansRobert N Butler
International Longevity Center-USA, New York, NY 10028, USA
J Gerontol A Biol Sci Med Sci 58:581-4. 2003
Recent progress in understanding the relationships among aging, replicative senescence, cell turnover and cancerHuber R Warner
Biology of Aging Program, National Institute on Aging, Bethesda, MD 20892, USA
In Vivo 16:393-6. 2002..The deacetylase activity of the sir2 gene product plays a role in longevity regulation in invertebrates, and also regulates p53 function in mammals, implying yet another link between aging and cancer in mammals...
Models of accelerated ageing can be informative about the molecular mechanisms of ageing and/or age-related pathologyHuber R Warner
Biology of Ageing Program, National Institute on Ageing, Bethesda, MD 20892, USA
Mech Ageing Dev 124:581-7. 2003..A possible common feature of these models may be an imbalance between loss of cells by apoptosis and subsequent cell replacement, leading gradually to a net loss of cells in multiple tissues...
An Aging Interventions Testing Program: study design and interim reportRichard A Miller
Department of Pathology and Geriatrics Center, University of Michigan, Ann Arbor VA Medical Center, Ann Arbor, MI 48109 2200, USA
Aging Cell 6:565-75. 2007..More data will be needed to determine if any of these compounds can extend maximal lifespan, but the current data show that NDGA reduces early life mortality risks in genetically heterogeneous mice at multiple test sites...
Head-to-head debate between Richard Miller and Paul Hasty/Jan Vijg. Aging Cell Vol. 3, Issue 2 (2004)Huber R Warner
Biology of Aging Program, National Institute on Aging, Bethesda, MD 20895, USA
Aging Cell 3:141-2. 2004
Current status of efforts to measure and modulate the biological rate of agingHuber R Warner
Biology of Aging Program, National Institute on Aging NIH, Bethesda, MD 20892, USA
J Gerontol A Biol Sci Med Sci 59:692-6. 2004..It is hoped that this will ultimately lead to interventions to delay the development of age-related pathology in humans...
Is there an antiaging medicine?Robert N Butler
International Longevity Center USA, New York, New York, USA
J Gerontol A Biol Sci Med Sci 57:B333-8. 2002..This article reports the findings of a consensus workshop that discussed what is known about existing and future interventions to slow, stop, or reverse aging in animals, and how these might be applied to humans through future research...
