Research Topics
| James P WarneSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Shaping the stress response: interplay of palatable food choices, glucocorticoids, insulin and abdominal obesityJames P Warne
Diabetes Center, University of California San Francisco, 513 Parnassus Avenue, Box 0534, San Francisco, CA 94143 0534, USA
Mol Cell Endocrinol 300:137-46. 2009..Considering stress is omnipresent in the workplace, palatable food ingestion may represent a means to combat the feeling of stress which is ultimately maladaptive when unresolved...
Mapping brain c-Fos immunoreactivity after insulin-induced voluntary lard intake: insulin- and lard-associated patternsJ P Warne
Department of Physiology, University of California San Francisco, San Francisco, CA 94143, USA
J Neuroendocrinol 19:794-808. 2007..The anterior paraventricular thalamic nucleus exhibited both patterns. These data collectively fit into a framework for food intake and reward and provide targets for pharmacological manipulation to influence the choice of food intake...
Metabolic and neuroendocrine consequences of a duodenal-jejunal bypass in rats on a choice dietJames P Warne
Departments of Physiology, University of California San Francisco, 94143, USA
Ann Surg 249:269-76. 2009..We sought to examine insulin-sensitive food intake behavior and neuroendocrine and metabolic variables of rats that had undergone a duodenal-jejunal bypass (DJB)...
Insulin and the constituent branches of the hepatic vagus interact to modulate hypothalamic and limbic neuropeptide mRNA expression differentiallyJ P Warne
Department of Physiology, University of California San Francisco, San Francisco, CA 94143, USA
J Neuroendocrinol 20:1067-77. 2008....
The gastroduodenal branch of the common hepatic vagus regulates voluntary lard intake, fat deposition, and plasma metabolites in streptozotocin-diabetic ratsJames P Warne
Dept of Physiology, Box 0444, Univ of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143, USA
Am J Physiol Endocrinol Metab 294:E190-200. 2008..These data suggest that the gastroduodenal branch of the vagus inhibits lard intake and regulates WAT deposition and plasma metabolite levels in STZ-diabetic rats...
Afferent signalling through the common hepatic branch of the vagus inhibits voluntary lard intake and modifies plasma metabolite levels in ratsJames P Warne
Department of Physiology, University of California San Francisco, San Francisco, CA 94143, USA
J Physiol 583:455-67. 2007..Collectively, these data suggest that afferent signalling through the common hepatic branch of the vagus inhibits lard, but not chow, intake, directs fat deposition and regulates plasma metabolite levels...
Comparison of superior mesenteric versus jugular venous infusions of insulin in streptozotocin-diabetic rats on the choice of caloric intake, body weight, and fat storesJames P Warne
Department of Physiology, Box 0444, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, California 94143, USA
Endocrinology 147:5443-51. 2006....
Hepatic branch vagotomy, like insulin replacement, promotes voluntary lard intake in streptozotocin-diabetic ratsJames P Warne
Department of Physiology, Box 0444, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, California 94143, USA
Endocrinology 148:3288-98. 2007..These actions may be modulated by insulin acting both centrally and peripherally...
Disengaging insulin from corticosterone: roles of each on energy intake and dispositionJames P Warne
Department of Physiology, University of California San Francisco, San Francisco, CA 94143, USA
Am J Physiol Regul Integr Comp Physiol 296:R1366-75. 2009..Collectively, these data show that corticosterone and insulin determine the intake, form, and compartmentalization of energy both independently and interactively...
Palatable foods, stress, and energy stores sculpt corticotropin-releasing factor, adrenocorticotropin, and corticosterone concentrations after restraintMichelle T Foster
Department of Physiology, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, California 94143 0444, USA
Endocrinology 150:2325-33. 2009..The results suggest strongly that ingestion of highly palatable foods reduces activity in the central stress response network, perhaps reducing the feeling of stressors...
From Malthus to motive: how the HPA axis engineers the phenotype, yoking needs to wantsNorman Pecoraro
Department of Physiology, University of California, San Francisco, CA 94143 0444, United States
Prog Neurobiol 79:247-340. 2006..Adverse side effects of this yoking under conditions of glucocorticoid excess are discussed...
Glucocorticoids and insulin both modulate caloric intake through actions on the brainMary F Dallman
Department of Physiology, University of California San Francisco, San Francisco, CA 94143 0444, USA
J Physiol 583:431-6. 2007..Both conditions of reduced food allowance and chronic stress excite glucocorticoid-augmented central neural networks that may lead toward ultimate abdominal obesity...
Diverse basal and stress-related phenotypes of Sprague Dawley rats from three vendorsNorman Pecoraro
Department of Physiology, School of Medicine, University of California San Francisco, 94143 0444, United States
Physiol Behav 89:598-610. 2006..Substantial phenotypic differences exist between Sprague Dawley rats from different vendors with respect to metabolism and HPA function. The metabolic feedback hypothesis was supported in two of the three vendors' rats...
Rapid alteration of stress-induced hypothalamic-pituitary-adrenal hormone secretion in the rat: a comparison of glucocorticoids and cannabinoidsAbigail B Ginsberg
Department of Physiology, University of California San Francisco, San Francisco, California, USA
Stress 13:248-57. 2010....
Glucocorticoids, the etiology of obesity and the metabolic syndromeMary F Dallman
Department of Physiology, UCSF, San Francisco, CA 94143 0444, USA
Curr Alzheimer Res 4:199-204. 2007..Correlative results from a clinical study support the powerful role of small changes in glucocorticoids in type 2 diabetes...
Glucocorticoids, chronic stress, and obesityMary F Dallman
University of California at San Francisco, San Francisco, CA 94143 0444, USA
Prog Brain Res 153:75-105. 2006..Finally, we briefly discuss the problems with this network that normally serves to aid in responses to chronic stress, in our current overindulged, and underexercised society...
Impairment of central leptin-mediated PI3K signaling manifested as hepatic steatosis independent of hyperphagia and obesityJames P Warne
Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA
Cell Metab 14:791-803. 2011..Together, our results indicate that central cellular leptin resistance in PI3K signaling manifests as hepatic steatosis without causing obesity...
Metabolic transceivers: in tune with the central melanocortin systemJames P Warne
Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA Electronic address
Trends Endocrinol Metab 24:68-75. 2013..This review focuses on most recent developments obtained from rodent studies on the function, metabolic regulation, and circuitry of the central melanocortin system...
Gene deletion reveals roles for annexin A1 in the regulation of lipolysis and IL-6 release in epididymal adipose tissueJames P Warne
Dept of Cellular and Molecular Neuroscience, Division of Neuroscience and Mental Health, Imperial College London, Hammersmith Campus, London, W12 0NN, UK
Am J Physiol Endocrinol Metab 291:E1264-73. 2006..Collectively, these studies suggest that ANXA1 supports aspects of adipose tissue mass and alters the sensitivity of epididymal adipose tissue to catecholamines, glucocorticoids, and LPS, thereby modulating lipolysis and IL-6 release...
Stress, diet and abdominal obesity: Y?James P Warne
Nat Med 13:781-3. 2007
