Jeffrey H Ware

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Effects of proton radiation dose, dose rate and dose fractionation on hematopoietic cells in mice
    J H Ware
    Department of Radiation Oncology, Division of Oncology Research, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6072, USA
    Radiat Res 174:325-30. 2010
  2. ncbi request reprint Establishment of human cancer cell clones with different characteristics: a model for screening chemopreventive agents
    Jeffrey H Ware
    Department of Radiation Oncology, Division of Oncology Research, University of Pennsylvania School of Medicine, 3620 Hamilton Walk, Philadelphia, PA 19104 6072, USA
    Anticancer Res 27:1-16. 2007
  3. ncbi request reprint Evaluation of cancer chemopreventive agents using clones derived from a human prostate cancer cell line
    Jeffrey H Ware
    Department of Radiation Oncology, Division of Oncology Research, University of Pennsylvania School of Medicine, 3620 Hamilton Walk, Philadelphia, PA 19104 6072, USA
    Anticancer Res 26:4177-83. 2006
  4. pmc Protective effects of dietary antioxidants on proton total-body irradiation-mediated hematopoietic cell and animal survival
    Chris O Wambi
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Radiat Res 172:175-86. 2009
  5. pmc Effects of selenomethionine in irradiated human thyroid epithelial cells and tumorigenicity studies
    Jeffrey H Ware
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Nutr Cancer 63:1114-21. 2011
  6. ncbi request reprint Effects of dietary supplements on the space radiation-induced reduction in total antioxidant status in CBA mice
    Jun Guan
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Radiat Res 165:373-8. 2006
  7. ncbi request reprint Protection against radiation-induced oxidative stress in cultured human epithelial cells by treatment with antioxidant agents
    X Steven Wan
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Int J Radiat Oncol Biol Phys 64:1475-81. 2006
  8. doi request reprint Dietary supplements reduce the cataractogenic potential of proton and HZE-particle radiation in mice
    James G Davis
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6072, USA
    Radiat Res 173:353-61. 2010
  9. pmc Effects of dietary antioxidant supplementation on the development of malignant lymphoma and other neoplastic lesions in mice exposed to proton or iron-ion radiation
    Ann R Kennedy
    Department of Radiation Oncology, Universtiy of Pennsylvania School of Medicine, Philadelphia, PA 19104 6072, USA
    Radiat Res 169:615-25. 2008
  10. ncbi request reprint Protection against adverse biological effects induced by space radiation by the Bowman-Birk inhibitor and antioxidants
    Ann R Kennedy
    Department of Radiation Oncology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Radiat Res 166:327-32. 2006

Collaborators

Detail Information

Publications21

  1. pmc Effects of proton radiation dose, dose rate and dose fractionation on hematopoietic cells in mice
    J H Ware
    Department of Radiation Oncology, Division of Oncology Research, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6072, USA
    Radiat Res 174:325-30. 2010
    ....
  2. ncbi request reprint Establishment of human cancer cell clones with different characteristics: a model for screening chemopreventive agents
    Jeffrey H Ware
    Department of Radiation Oncology, Division of Oncology Research, University of Pennsylvania School of Medicine, 3620 Hamilton Walk, Philadelphia, PA 19104 6072, USA
    Anticancer Res 27:1-16. 2007
    ....
  3. ncbi request reprint Evaluation of cancer chemopreventive agents using clones derived from a human prostate cancer cell line
    Jeffrey H Ware
    Department of Radiation Oncology, Division of Oncology Research, University of Pennsylvania School of Medicine, 3620 Hamilton Walk, Philadelphia, PA 19104 6072, USA
    Anticancer Res 26:4177-83. 2006
    ..The successful use of clonal selection through fluctuation analysis of human cancer cells as a means for studying tumor progression has been previously reported...
  4. pmc Protective effects of dietary antioxidants on proton total-body irradiation-mediated hematopoietic cell and animal survival
    Chris O Wambi
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Radiat Res 172:175-86. 2009
    ..Taken together, oral supplementation with antioxidants appears to be an effective approach for radioprotection of hematopoietic cells and improvement of animal survival after proton TBI...
  5. pmc Effects of selenomethionine in irradiated human thyroid epithelial cells and tumorigenicity studies
    Jeffrey H Ware
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Nutr Cancer 63:1114-21. 2011
    ....
  6. ncbi request reprint Effects of dietary supplements on the space radiation-induced reduction in total antioxidant status in CBA mice
    Jun Guan
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Radiat Res 165:373-8. 2006
    ..These results indicate that BBIC, L-SeM and the selected antioxidant combinations may serve as countermeasures for space radiation-induced adverse biological effects...
  7. ncbi request reprint Protection against radiation-induced oxidative stress in cultured human epithelial cells by treatment with antioxidant agents
    X Steven Wan
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Int J Radiat Oncol Biol Phys 64:1475-81. 2006
    ..To evaluate the protective effects of antioxidant agents against space radiation-induced oxidative stress in cultured human epithelial cells...
  8. doi request reprint Dietary supplements reduce the cataractogenic potential of proton and HZE-particle radiation in mice
    James G Davis
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6072, USA
    Radiat Res 173:353-61. 2010
    ..These results indicate that BBIC and the antioxidant formulation evaluated in this study could be useful for protecting astronauts against space radiation-induced cataracts during or after long-term manned space missions...
  9. pmc Effects of dietary antioxidant supplementation on the development of malignant lymphoma and other neoplastic lesions in mice exposed to proton or iron-ion radiation
    Ann R Kennedy
    Department of Radiation Oncology, Universtiy of Pennsylvania School of Medicine, Philadelphia, PA 19104 6072, USA
    Radiat Res 169:615-25. 2008
    ..These results suggest that dietary supplements could be useful in the prevention of malignancies and other neoplastic lesions developing from exposure to space radiation...
  10. ncbi request reprint Protection against adverse biological effects induced by space radiation by the Bowman-Birk inhibitor and antioxidants
    Ann R Kennedy
    Department of Radiation Oncology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Radiat Res 166:327-32. 2006
    ....
  11. pmc Gamma-radiation (GR) triggers a unique gene expression profile associated with cell death compared to proton radiation (PR) in mice in vivo
    Niklas Finnberg
    Laboratory of Molecular Oncology and Cell Cycle Regulation, The Institute for Translational Medicine and Therapeutics, The Abramson Comprehensive Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Cancer Biol Ther 7:2023-33. 2008
    ..In contrast to PR, GR may, in a cell type specific manner, trigger a more diverse non-random stress-response that mediates apoptosis partially independent of the extent of DNA damage...
  12. pmc Dietary antioxidants protect hematopoietic cells and improve animal survival after total-body irradiation
    Chris Wambi
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Radiat Res 169:384-96. 2008
    ....
  13. pmc Analysis of white blood cell counts in mice after gamma- or proton-radiation exposure
    Casey J Maks
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Radiat Res 176:170-6. 2011
    ....
  14. ncbi request reprint Suppression of the later stages of radiation-induced carcinogenesis by antioxidant dietary formulations
    Ann R Kennedy
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6072, USA
    Radiat Res 176:62-70. 2011
    ....
  15. ncbi request reprint Three immunoassays based on monoclonal antibodies specific for prostate specific antigen (PSA), alpha-1-antichymotrypsin (ACT), and the PSA-ACT complex
    X Steven Wan
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6072, USA
    Prostate 56:131-41. 2003
    ....
  16. ncbi request reprint Selenomethionine protects against adverse biological effects induced by space radiation
    Ann R Kennedy
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, 195 John Morgan Building, 3620 Hamilton Walk, Philadelphia, PA, USA
    Free Radic Biol Med 36:259-66. 2004
    ....
  17. pmc Acute biological effects of simulating the whole-body radiation dose distribution from a solar particle event using a porcine model
    Jolaine M Wilson
    University of Pennsylvania, Department of Radiation Oncology, Philadelphia, Pennsylvania 19104, USA
    Radiat Res 176:649-59. 2011
    ....
  18. ncbi request reprint Bowman-Birk inhibitor concentrate: a novel therapeutic agent for patients with active ulcerative colitis
    Gary R Lichtenstein
    Department of Medicine, Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4283, USA
    Dig Dis Sci 53:175-80. 2008
    ..22). No severe adverse events were observed. This trial suggests a potential benefit over placebo for both achieving clinical response and induction of remission in patients with active ulcerative colitis without apparent toxicity...
  19. ncbi request reprint Detection of Bowman-Birk inhibitor and anti-Bowman-Birk inhibitor antibodies in sera of humans and animals treated with Bowman-Birk inhibitor concentrate
    X Steven Wan
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Nutr Cancer 43:167-73. 2002
    ..These results suggest that orally ingested BBI is absorbed by human subjects and animals and that some animals develop antibodies to BBI in response to treatment with BBIC...
  20. ncbi request reprint Detection of oxidative stress induced by low- and high-linear energy transfer radiation in cultured human epithelial cells
    X Steven Wan
    Department of Radiation Oncology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Radiat Res 163:364-8. 2005
    ....
  21. ncbi request reprint Standardization of a fluorometric assay for measuring oxidative stress in irradiated cells
    X Steven Wan
    Department of Radiation Oncology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Radiat Res 163:232-40. 2005
    ....