Margaret C Wardle

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. pmc Lack of association between COMT and working memory in a population-based cohort of healthy young adults
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA
    Neuropsychopharmacology 38:1253-63. 2013
  2. pmc Iowa Gambling Task performance and emotional distress interact to predict risky sexual behavior in individuals with dual substance and HIV diagnoses
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA
    J Clin Exp Neuropsychol 32:1110-21. 2010
  3. pmc Effects of amphetamine on reactivity to emotional stimuli
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, MC 3077, University of Chicago, 5841 S Maryland Ave, Chicago, IL, USA
    Psychopharmacology (Berl) 220:143-53. 2012
  4. pmc Amphetamine as a social drug: effects of d-amphetamine on social processing and behavior
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841 S Maryland Ave, MC 3077, Chicago, IL 60637, USA
    Psychopharmacology (Berl) 223:199-210. 2012
  5. doi request reprint Effects of oxycodone on brain responses to emotional images
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841 S Maryland Ave, MC 3077, Chicago, IL, 60637, USA
    Psychopharmacology (Berl) 231:4403-15. 2014
  6. pmc Caffeine increases psychomotor performance on the effort expenditure for rewards task
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841 S Maryland Ave, MC 3077, Chicago, IL 60637, USA
    Pharmacol Biochem Behav 102:526-31. 2012
  7. doi request reprint Acute effects of MDMA on autonomic cardiac activity and their relation to subjective prosocial and stimulant effects
    Christine M Clark
    Department of Psychiatry and Behavioral Neurosciences, University of Chicago, Chicago, Illinois, USA
    Psychophysiology 52:429-35. 2015
  8. pmc Amping up effort: effects of d-amphetamine on human effort-based decision-making
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci 31:16597-602. 2011
  9. pmc Effect of d-amphetamine on post-error slowing in healthy volunteers
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841 S Maryland Ave, MC 3077, Chicago, IL 60637, USA
    Psychopharmacology (Berl) 220:109-15. 2012
  10. pmc 'Ecstasy' as a social drug: MDMA preferentially affects responses to emotional stimuli with social content
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA
    Soc Cogn Affect Neurosci 9:1076-81. 2014

Collaborators

Detail Information

Publications15

  1. pmc Lack of association between COMT and working memory in a population-based cohort of healthy young adults
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA
    Neuropsychopharmacology 38:1253-63. 2013
    ....
  2. pmc Iowa Gambling Task performance and emotional distress interact to predict risky sexual behavior in individuals with dual substance and HIV diagnoses
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA
    J Clin Exp Neuropsychol 32:1110-21. 2010
    ..Our results are interpreted using the somatic marker hypothesis and indicate that the IGT identifies HIV+ SDIs for whom psychological distress influences HIV risk...
  3. pmc Effects of amphetamine on reactivity to emotional stimuli
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, MC 3077, University of Chicago, 5841 S Maryland Ave, Chicago, IL, USA
    Psychopharmacology (Berl) 220:143-53. 2012
    ..e., euphoria). However, recent findings suggest drugs may also alter emotional reactivity to external stimuli, and that this may occur independently of direct effects on mood...
  4. pmc Amphetamine as a social drug: effects of d-amphetamine on social processing and behavior
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841 S Maryland Ave, MC 3077, Chicago, IL 60637, USA
    Psychopharmacology (Berl) 223:199-210. 2012
    ..One way that drugs may affect social behavior is by altering social processing, for example by decreasing perceptions of negative emotion in others...
  5. doi request reprint Effects of oxycodone on brain responses to emotional images
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841 S Maryland Ave, MC 3077, Chicago, IL, 60637, USA
    Psychopharmacology (Berl) 231:4403-15. 2014
    ..Such emotional effects may motivate misuse of oxycodone (OXY), a widely abused opiate. Yet, we know little about how OXY affects neural circuits underlying emotional processing in humans...
  6. pmc Caffeine increases psychomotor performance on the effort expenditure for rewards task
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841 S Maryland Ave, MC 3077, Chicago, IL 60637, USA
    Pharmacol Biochem Behav 102:526-31. 2012
    ..This study provides a starting point for exploring contributions of the adenosine system to motivation in humans...
  7. doi request reprint Acute effects of MDMA on autonomic cardiac activity and their relation to subjective prosocial and stimulant effects
    Christine M Clark
    Department of Psychiatry and Behavioral Neurosciences, University of Chicago, Chicago, Illinois, USA
    Psychophysiology 52:429-35. 2015
    ..At 1.5 mg/kg, subjective prosocial effects correlated with stimulated feelings and PEP, but not RSA. This suggests sympathetic, rather than parasympathetic, effects relate to the prosocial effects of MDMA. ..
  8. pmc Amping up effort: effects of d-amphetamine on human effort-based decision-making
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci 31:16597-602. 2011
    ..These findings help elucidate neurochemical substrates of choice, with implications for neuropsychiatric diseases characterized by dopaminergic dysfunction and motivational deficits...
  9. pmc Effect of d-amphetamine on post-error slowing in healthy volunteers
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841 S Maryland Ave, MC 3077, Chicago, IL 60637, USA
    Psychopharmacology (Berl) 220:109-15. 2012
    ..Post-error slowing has long been considered a sign of healthy error detection and an important component of cognitive function. However, the neuropharmacological processes underlying post-error slowing are poorly understood...
  10. pmc 'Ecstasy' as a social drug: MDMA preferentially affects responses to emotional stimuli with social content
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA
    Soc Cogn Affect Neurosci 9:1076-81. 2014
    ..This effect may also contribute to its attractiveness to recreational users. ..
  11. pmc Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13)
    Amy B Hart
    Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 7:e42646. 2012
    ..Our approach provides a case study for analysis of high-dimensional intermediate pharmacogenomic phenotypes, which may be more tractable than clinical diagnoses...
  12. pmc Effects of MDMA and Intranasal oxytocin on social and emotional processing
    Matthew G Kirkpatrick
    Department of Psychiatry and Behavioral Neurosciences, University of Chicago, Chicago, IL, USA
    Neuropsychopharmacology 39:1654-63. 2014
    ..The present findings provide only limited support for the idea that oxytocin produces the prosocial effects of MDMA...
  13. pmc The caudate signals bad reputation during trust decisions
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 8:e68884. 2013
    ..05 whole brain corrected. Our findings suggest that the caudate is involved in signaling and integrating reputations gained through experience into trust decisions, demonstrating a neural basis for this key social process. ..
  14. pmc MDMA decreases the effects of simulated social rejection
    Charles G Frye
    Department of Psychiatry and Behavioral Neurosciences, University of Chicago, USA
    Pharmacol Biochem Behav 117:1-6. 2014
    ..These phenomena merit further study in non-simulated social environments...
  15. pmc Effect of social stress during acute nicotine abstinence
    Margaret C Wardle
    Department of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841 S Maryland Ave MC 3077, Chicago, IL 60637, USA
    Psychopharmacology (Berl) 218:39-48. 2011
    ..Relapse to smoking is often precipitated by stress, yet little is known about the effects of nicotine withdrawal on responses to acute stress, or whether nicotine replacement reverses withdrawal-induced changes in stress response...