Monika A Ward
Affiliation: University of Hawaii
Riel J, Yamauchi Y, Ruthig V, Malinta Q, Blanco M, Moretti C, et al
. Rescue of Sly Expression Is Not Sufficient to Rescue Spermiogenic Phenotype of Mice with Deletions of Y Chromosome Long Arm. Genes (Basel). 2019;10: pubmed publisher
..Together, the data suggest that Sly deficiency is not the sole underlying cause of the infertile phenotype of mice with NPYq deletions and imply the involvement of another NPYq gene. ..
Balaan C, Corley M, Eulalio T, Leite Ahyo K, Pang A, Fang R, et al
. Juvenile Shank3b deficient mice present with behavioral phenotype relevant to autism spectrum disorder. Behav Brain Res. 2019;356:137-147 pubmed publisher
..Our findings underscore the importance of utilizing Shank mutant models to understand the impact of this gene in ASD etiology, whichmay enable future studies focusing on etiological gene-environment interactions in ASD. ..
Ward M. Intracytoplasmic sperm injection effects in infertile azh mutant mice. Biol Reprod. 2005;73:193-200 pubmed
..Moreover, serial (successive generations) ICSI is highly efficient in maintaining valuable mice with fertility problems. ..
Ortega E, Ruthig V, Ward M. Sry-Independent Overexpression of Sox9 Supports Spermatogenesis and Fertility in the Mouse. Biol Reprod. 2015;93:141 pubmed publisher
..Although transgenic Sox9 overexpression in the absence of Sry results in certain testicular abnormalities, it does not translate into fertility impairment. ..
Yamauchi Y, Riel J, Ruthig V, Ortega E, Mitchell M, Ward M. Two genes substitute for the mouse Y chromosome for spermatogenesis and reproduction. Science. 2016;351:514-6 pubmed publisher
..Our findings support the existence of functional redundancy between the Y chromosome genes and their homologs encoded on other chromosomes. ..