Research Topics
Genomes and Genes
Species | Yanling WangSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneuronsYanling Wang
Department of Psychiatry, Nina Ireland Laboratory of Developmental Neurobiology, University of California, San Francisco, San Francisco, California 94158, USA
J Neurosci 30:5334-45. 2010..This contrasts with Dlx1, whose function is required for dendrite innervating (calretinin(+), somatostatin(+), and neuropeptide Y(+)) interneurons (Cobos et al., 2005)...
CXCR4 and CXCR7 have distinct functions in regulating interneuron migrationYanling Wang
Department of Psychiatry, University of California, San Francisco, CA 94158, USA
Neuron 69:61-76. 2011..On the other hand, CXCL12 stimulation of CXCR7, but not CXCR4, promoted MAP kinase signaling. Thus, we suggest that CXCR4 and CXCR7 have distinct roles and signal transduction in regulating interneuron movement and laminar positioning...
Seizures, enhanced excitation, and increased vesicle number in Lis1 mutant miceJoel S F Greenwood
Graduate Program in Neuroscience, University of California, San Francisco, San Francisco, CA 94143, USA
Ann Neurol 66:644-53. 2009..Using this mouse model, we examined the functional impact of LIS1 deficiency with particular focus on excitatory glutamate-mediated synaptic transmission...
Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardiumBen Van Handel
Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA
Cell 150:590-605. 2012..These results reveal unexpected plasticity in embryonic endothelium such that loss of a single master regulator can induce ectopic cardiomyogenesis from endothelial cells...
Arcuate nucleus expression of NKX2.1 and DLX and lineages expressing these transcription factors in neuropeptide Y(+), proopiomelanocortin(+), and tyrosine hydroxylase(+) neurons in neonatal and adult miceCindy L Yee
Nina Ireland Laboratory of Developmental Neurobiology, University of California San Francisco, Genetics and Development, San Francisco, California 94158 2611, USA
J Comp Neurol 517:37-50. 2009..These results have implications for the genetic control of arcuate development and function and for the utility of the Nkx2.1-Cre and Dlx5/6i-Cre mouse lines to alter gene expression in the developing arcuate...
Aberrant dentate gyrus cytoarchitecture and fiber lamination in Lis1 mutant miceYanling Wang
Epilepsy Research Laboratory, Department of Neurological Surgery, University of California, San Francisco, CA 94143, USA
Hippocampus 18:758-65. 2008..The functional consequences of hippocampal granule cell dispersion could offer critical insight to the epileptic and cognitive disorder associated with LIS1 haploinsufficiency...
Granule cell dispersion and aberrant neurogenesis in the adult hippocampus of an LIS1 mutant mouseYanling Wang
Epilepsy Research Laboratory in the Department of Neurological Surgery and PIBS Graduate Program in Neuroscience, University of California, San Francisco, San Francisco, CA 94143, USA
Dev Neurosci 29:91-8. 2007..Thus, LIS1 haploinsufficiency can lead to abnormal cell proliferation, migration and differentiation in the adult dentate gyrus...
Trophoblasts regulate the placental hematopoietic niche through PDGF-B signalingAkanksha Chhabra
Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA
Dev Cell 22:651-9. 2012..These data provide genetic evidence of a signaling pathway that is required to restrict erythroid differentiation to specific anatomical niches during development...
Neocortical hyperexcitability in a human case of tuberous sclerosis complex and mice lacking neuronal expression of TSC1Yanling Wang
Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA
Ann Neurol 61:139-52. 2007..These studies were designed to assess whether TSC gene inactivation alters excitability...
A role for the mTOR pathway in surface expression of AMPA receptorsYanling Wang
Epilepsy Research Laboratory in the Department of Neurological Surgery and PIBS Graduate Program in Neuroscience, University of California, Box 0520, 513 Parnassus Ave, San Francisco, CA 94143, USA
Neurosci Lett 401:35-9. 2006..Our results suggest a role for the mTOR pathway in surface expression of AMPA receptors on cortical neurons...
The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulationKatrin E Rhodes
Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA
Cell Stem Cell 2:252-63. 2008..These data suggest that, in addition to providing a niche for a large pool of HSCs prior to liver colonization, the placenta is a true site of HSC generation...
