Xiaodu Wang

Summary

Affiliation: University of Texas at San Antonio
Country: USA

Publications

  1. ncbi request reprint A mixed mode fracture toughness test of bone-biomaterial interfaces
    X Wang
    Mechanical Engineering, The University of Texas at San Antonio, 78249, USA
    J Biomed Mater Res 53:664-72. 2000
  2. pmc A novel scratching approach for measuring age-related changes in the in situ toughness of bone
    X Wang
    Department of Mechanical Engineering and Biomechanics, The University of Texas at San Antonio, 6900 North Loop 1604 West, San Antonio, TX 78249, USA
    J Biomech 40:1401-4. 2007
  3. pmc A novel approach to assess post-yield energy dissipation of bone in tension
    Xiaodu Wang
    Department of Mechanical Engineering, University of Texas at San Antonio, 6900 North Loop 1604 West, San Antonio, TX 78249, USA
    J Biomech 40:674-7. 2007
  4. pmc Prediction of microdamage formation using a mineral-collagen composite model of bone
    Xiaodu Wang
    Mechanical Engineering and Biomechanics Department, The University of Texas at San Antonio, 6900 North Loop 1604 West, San Antonio, TX 79249, USA
    J Biomech 39:595-602. 2006
  5. ncbi request reprint The toughness of cortical bone and its relationship with age
    Xiaodu Wang
    Department of Mechanical Engineering and Biomechanics, The University of Texas at San Antonio, San Antonio, TX 78249 0670, USA
    Ann Biomed Eng 32:123-35. 2004
  6. ncbi request reprint Age-related changes of noncalcified collagen in human cortical bone
    Xiaodu Wang
    Mechanical Engineering and Biomechanics, The University of Texas at San Antonio, San Antonio, TX 78249, USA
    Ann Biomed Eng 31:1365-71. 2003
  7. ncbi request reprint Determination of cortical bone porosity and pore size distribution using a low field pulsed NMR approach
    Xiaodu Wang
    Department of Mechanical Engineering and Biomechanics, College of Engineering, University of Texas at San Antonio, 6900 North Loop, 1604 West, San Antonio, TX 78249, USA
    J Orthop Res 21:312-9. 2003
  8. ncbi request reprint The role of collagen in determining bone mechanical properties
    X Wang
    Mechanical Engineering, University of Texas at San Antonio, 78249, USA
    J Orthop Res 19:1021-6. 2001
  9. ncbi request reprint Age-related changes in the collagen network and toughness of bone
    X Wang
    Department of Mechanical Engineering, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    Bone 31:1-7. 2002
  10. ncbi request reprint Effects of collagen unwinding and cleavage on the mechanical integrity of the collagen network in bone
    X Wang
    Mechanical Engineering and Biomechanics, The University of Texas at San Antonio, 6900 North Loop 1604 West, San Antonio, Texas 78249, USA
    Calcif Tissue Int 71:186-92. 2002

Collaborators

Detail Information

Publications26

  1. ncbi request reprint A mixed mode fracture toughness test of bone-biomaterial interfaces
    X Wang
    Mechanical Engineering, The University of Texas at San Antonio, 78249, USA
    J Biomed Mater Res 53:664-72. 2000
    ..It is expected that the mixed mode technique can provide an effective means for investigators to study the mechanical integrity of bone-biomaterial interfaces under complex loading conditions...
  2. pmc A novel scratching approach for measuring age-related changes in the in situ toughness of bone
    X Wang
    Department of Mechanical Engineering and Biomechanics, The University of Texas at San Antonio, 6900 North Loop 1604 West, San Antonio, TX 78249, USA
    J Biomech 40:1401-4. 2007
    ..A significant difference in the estimated removal energy density (u(s)) in the secondary osteons was found between the middle-aged and elderly groups (5.49+/-0.696 vs. 4.09+/-1.30 N/mm(2), respectively)...
  3. pmc A novel approach to assess post-yield energy dissipation of bone in tension
    Xiaodu Wang
    Department of Mechanical Engineering, University of Texas at San Antonio, 6900 North Loop 1604 West, San Antonio, TX 78249, USA
    J Biomech 40:674-7. 2007
    ..These results implicate that this novel approach could detect the age-related differences in energy dissipation of bone and may aid in understanding the underlying mechanisms of such changes...
  4. pmc Prediction of microdamage formation using a mineral-collagen composite model of bone
    Xiaodu Wang
    Mechanical Engineering and Biomechanics Department, The University of Texas at San Antonio, 6900 North Loop 1604 West, San Antonio, TX 79249, USA
    J Biomech 39:595-602. 2006
    ....
  5. ncbi request reprint The toughness of cortical bone and its relationship with age
    Xiaodu Wang
    Department of Mechanical Engineering and Biomechanics, The University of Texas at San Antonio, San Antonio, TX 78249 0670, USA
    Ann Biomed Eng 32:123-35. 2004
    ..In addition, a special emphasis is placed on age-related changes in the toughness of bone...
  6. ncbi request reprint Age-related changes of noncalcified collagen in human cortical bone
    Xiaodu Wang
    Mechanical Engineering and Biomechanics, The University of Texas at San Antonio, San Antonio, TX 78249, USA
    Ann Biomed Eng 31:1365-71. 2003
    ..These results suggest that age-related changes in the noncalcified collagenous matrix induced by bone remodeling may have likely effects on bone quality...
  7. ncbi request reprint Determination of cortical bone porosity and pore size distribution using a low field pulsed NMR approach
    Xiaodu Wang
    Department of Mechanical Engineering and Biomechanics, College of Engineering, University of Texas at San Antonio, 6900 North Loop, 1604 West, San Antonio, TX 78249, USA
    J Orthop Res 21:312-9. 2003
    ..In addition, this study indicates that the age-related changes in cortical porosity relate predominantly to Haversian canals, whereas the porosity of osteocytic lacunae appears to be independent of age...
  8. ncbi request reprint The role of collagen in determining bone mechanical properties
    X Wang
    Mechanical Engineering, University of Texas at San Antonio, 78249, USA
    J Orthop Res 19:1021-6. 2001
    ..These results suggest that the collagen network plays an important role in the toughness of bone, but has little effect on the stiffness of bone, thereby supporting the hypothesis of this study...
  9. ncbi request reprint Age-related changes in the collagen network and toughness of bone
    X Wang
    Department of Mechanical Engineering, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    Bone 31:1-7. 2002
    ..Also, the results suggest that nonenzymatic glycation may be an important contributing factor causing changes in collagen and, consequently, leading to the age-related deterioration of bone quality...
  10. ncbi request reprint Effects of collagen unwinding and cleavage on the mechanical integrity of the collagen network in bone
    X Wang
    Mechanical Engineering and Biomechanics, The University of Texas at San Antonio, 6900 North Loop 1604 West, San Antonio, Texas 78249, USA
    Calcif Tissue Int 71:186-92. 2002
    ....
  11. pmc Age-related effect on the concentration of collagen crosslinks in human osteonal and interstitial bone tissue
    Jeffry S Nyman
    Department of Mechanical Engineering and Biomechanics, The University of Texas at San Antonio, San Antonio, TX 78249, USA
    Bone 39:1210-7. 2006
    ..Such changes could potentially reduce the inherent quality of the bone tissue in the elderly skeleton...
  12. pmc The influence of water removal on the strength and toughness of cortical bone
    Jeffry S Nyman
    Department of Mechanical Engineering and Biomechanics, University of Texas at San Antonio, 6900 North Loop 1604 West, TX 78249, USA
    J Biomech 39:931-8. 2006
    ..Therefore, we speculate that loss of water in the collagen phase decreases the toughness of bone, whereas loss of water associated with the mineral phase decreases both bone strength and toughness...
  13. pmc Age-related factors affecting the postyield energy dissipation of human cortical bone
    Jeffry S Nyman
    Department of Mechanical Engineering and Biomechanics, The University of Texas at San Antonio, San Antonio, Texas 78249, USA
    J Orthop Res 25:646-55. 2007
    ..Among them, pentosidine concentration had the greatest contribution to plastic strain energy and was the best explanatory variable of damage accumulation...
  14. ncbi request reprint Effect of ultrastructural changes on the toughness of bone
    Jeffry S Nyman
    Mechanical Engineering and Biomechanics, University of Texas at San Antonio, 6900 North Loop 1604 West, San Antonio, TX 78249, USA
    Micron 36:566-82. 2005
    ..Finally, we describe how changes in the ultrastructure-caused by osteogenesis imperfecta, gamma irradiation, fluoride treatment, and aging affect the toughness and competence of bone...
  15. ncbi request reprint Collagen and bone viscoelasticity: a dynamic mechanical analysis
    Junro Yamashita
    Center for Clinical Bioengineering, The University of Texas Health Science Center, San Antonio, Texas 78284, USA
    J Biomed Mater Res 63:31-6. 2002
    ..These results suggest that at a constant frequency the denaturation of collagen triple-helical molecules may have few effects on the viscoelasticity of bone, but moisture may play a prominent role in determining this property...
  16. pmc Collagen mutation causes changes of the microdamage morphology in bone of an OI mouse model
    X Neil Dong
    Department of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX 78249, USA
    Bone 47:1071-5. 2010
    ....
  17. pmc In situ mechanical behavior of mineral crystals in human cortical bone under compressive load using synchrotron X-ray scattering techniques
    Bijay Giri
    Department of Mechanical Engineering, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA
    J Mech Behav Biomed Mater 14:101-12. 2012
    ..By examining the in situ behavior, the contribution of mineral crystals to load bearing and the bulk behavior of bone are discussed...
  18. pmc Post-yield nanomechanics of human cortical bone in compression using synchrotron X-ray scattering techniques
    X Neil Dong
    Department of Mechanical Engineering, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA
    J Biomech 44:676-82. 2011
    ....
  19. pmc Probabilistic failure analysis of bone using a finite element model of mineral-collagen composites
    X Neil Dong
    Department of Mechanical Engineering, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA
    J Biomech 42:202-9. 2009
    ..The findings of this study may help understanding the post-yield behavior of bone at the ultrastructural level and shed light on the underlying mechanism of bone fractures...
  20. pmc Constitutive relationship of tissue behavior with damage accumulation of human cortical bone
    Qing Luo
    Mechanical Engineering, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA
    J Biomech 43:2356-61. 2010
    ..The results of this study may help in developing a constitutive model for predicting the mechanical behavior of cortical bone tissues...
  21. pmc Progressive post-yield behavior of human cortical bone in shear
    Xuanliang N Dong
    Department of Health and Kinesiology, The University of Texas at Tyler, Tyler, TX, USA
    Bone 53:1-5. 2013
    ..Nonetheless, the results of this study suggest that the intrinsic mechanism of plastic deformation of human cortical bone may be independent of loading modes...
  22. pmc Orientation dependence of progressive post-yield behavior of human cortical bone in compression
    Xuanliang N Dong
    Department of Health and Kinesiology, The University of Texas at Tyler, Tyler, TX, USA
    J Biomech 45:2829-34. 2012
    ....
  23. doi request reprint Mechanistic modeling of a nanoscratch test for determination of in situ toughness of bone
    Anowarul Islam
    Mechanical Engineering, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA
    J Mech Behav Biomed Mater 5:156-64. 2012
    ..The experimental results indicated that the nanoscratch test could sensitively detect the in situ brittleness and strength of bone from the animal models...
  24. pmc Random field assessment of nanoscopic inhomogeneity of bone
    X Neil Dong
    Department of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX 78249, USA
    Bone 47:1080-4. 2010
    ..Indeed, generation of such random fields will facilitate multi-scale modeling of bone in more pragmatic details...
  25. pmc Measurements of mobile and bound water by nuclear magnetic resonance correlate with mechanical properties of bone
    Jeffry S Nyman
    Vanderbilt Center for Bone Biology, Vanderbilt University Medical Center, Nashville, TN 37215, USA
    Bone 42:193-9. 2008
    ..The results of this study indicate that quantifying mobile and bound water with magnetic resonance techniques could potentially serve as indicators of bone quality...
  26. ncbi request reprint Effect of diabetes mellitus on the material properties of the distal tibia
    John G Fleischli
    Foot and Ankle Associates of Central Illinois LLC, Jacksonville, 62650, USA
    J Am Podiatr Med Assoc 96:91-5. 2006
    ..29), yield strength (P = .90), ultimate strength (P = .46), and fracture toughness (P = .78), leading to speculation that diabetes has an effect similar to that of aging on the musculoskeletal system...