Steven J Wang

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Identifying and improving knowledge deficits of emergency airway management of tracheotomy and laryngectomy patients: a pilot patient safety initiative
    Ivan H El-Sayed
    Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, CA 94115, USA
    Int J Otolaryngol 2010:638742. 2010
  2. doi request reprint Role of hyaluronan synthase 2 to promote CD44-dependent oral cavity squamous cell carcinoma progression
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, Veterans Affairs Medical Center, San Francisco, California, USA
    Head Neck 35:511-20. 2013
  3. ncbi request reprint Hyaluronan and the interaction between CD44 and epidermal growth factor receptor in oncogenic signaling and chemotherapy resistance in head and neck cancer
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery, Veterans Affairs Medical Center, University of California, San Francisco, USA
    Arch Otolaryngol Head Neck Surg 132:771-8. 2006
  4. ncbi request reprint Association of CD44 V3-containing isoforms with tumor cell growth, migration, matrix metalloproteinase expression, and lymph node metastasis in head and neck cancer
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery, Veterans Affairs Medical Center, University of California, San Francisco, California, USA
    Head Neck 29:550-8. 2007
  5. ncbi request reprint The influence of hyaluronan-CD44 interaction on topoisomerase II activity and etoposide cytotoxicity in head and neck cancer
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery and Endocrine Unit, Department of Medicine, Veterans Affairs Medical Center, University of California, San Francisco, USA
    Arch Otolaryngol Head Neck Surg 133:281-8. 2007
  6. pmc Role of hyaluronan-mediated CD44 signaling in head and neck squamous cell carcinoma progression and chemoresistance
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery, University of California at San Francisco, San Francisco, California 94115, USA
    Am J Pathol 178:956-63. 2011
  7. ncbi request reprint Hyaluronan-CD44 promotes phospholipase C-mediated Ca2+ signaling and cisplatin resistance in head and neck cancer
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery and Endocrine Unit, Department of Medicine, University of California San Francisco, 4150 Clement Street 112B, San Francisco, CA 94121, USA
    Arch Otolaryngol Head Neck Surg 132:19-24. 2006
  8. doi request reprint Parotidectomy--Anatomical considerations
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, California
    Clin Anat 25:12-8. 2012
  9. pmc CD44 variant isoforms in head and neck squamous cell carcinoma progression
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, Veterans Affairs Medical Center, USA
    Laryngoscope 119:1518-30. 2009
  10. pmc Reduction of hyaluronan-CD44-mediated growth, migration, and cisplatin resistance in head and neck cancer due to inhibition of Rho kinase and PI-3 kinase signaling
    Carlos Torre
    Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, San Francisco, CA 94121, USA
    Arch Otolaryngol Head Neck Surg 136:493-501. 2010

Collaborators

Detail Information

Publications30

  1. pmc Identifying and improving knowledge deficits of emergency airway management of tracheotomy and laryngectomy patients: a pilot patient safety initiative
    Ivan H El-Sayed
    Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, CA 94115, USA
    Int J Otolaryngol 2010:638742. 2010
    ..A knowledge deficit is identified in caregivers expected to provide emergency management of patients with airway anatomy altered by subspecialty surgeons. Safety initiatives such as the EAA form may improve knowledge among providers...
  2. doi request reprint Role of hyaluronan synthase 2 to promote CD44-dependent oral cavity squamous cell carcinoma progression
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, Veterans Affairs Medical Center, San Francisco, California, USA
    Head Neck 35:511-20. 2013
    ..HA is primarily synthesized by hyaluronan synthases, and the current study investigated the role of hyaluronan synthase 2 (HAS 2) in oral cavity carcinoma progression behaviors...
  3. ncbi request reprint Hyaluronan and the interaction between CD44 and epidermal growth factor receptor in oncogenic signaling and chemotherapy resistance in head and neck cancer
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery, Veterans Affairs Medical Center, University of California, San Francisco, USA
    Arch Otolaryngol Head Neck Surg 132:771-8. 2006
    ..We recently determined that HA-CD44 promotes phospholipase C-mediated calcium signaling and cisplatin resistance in HNSCC...
  4. ncbi request reprint Association of CD44 V3-containing isoforms with tumor cell growth, migration, matrix metalloproteinase expression, and lymph node metastasis in head and neck cancer
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery, Veterans Affairs Medical Center, University of California, San Francisco, California, USA
    Head Neck 29:550-8. 2007
    ..The objective of this study was to investigate whether CD44 v3-containing isoforms are involved in head and neck squamous cell carcinoma (HNSCC) tumor progression...
  5. ncbi request reprint The influence of hyaluronan-CD44 interaction on topoisomerase II activity and etoposide cytotoxicity in head and neck cancer
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery and Endocrine Unit, Department of Medicine, Veterans Affairs Medical Center, University of California, San Francisco, USA
    Arch Otolaryngol Head Neck Surg 133:281-8. 2007
    ..We recently determined that HA-CD44 interaction promotes PLC-mediated Ca(2+) signaling and cisplatin resistance in HNSCC...
  6. pmc Role of hyaluronan-mediated CD44 signaling in head and neck squamous cell carcinoma progression and chemoresistance
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery, University of California at San Francisco, San Francisco, California 94115, USA
    Am J Pathol 178:956-63. 2011
    ..Finally, EGFR-mediated pathways play major roles in the HA/CD44 promotion of chemoresistance in HNSCC. Understanding HA/CD44-mediated signaling pathways may lead to improved treatment of HNSCC...
  7. ncbi request reprint Hyaluronan-CD44 promotes phospholipase C-mediated Ca2+ signaling and cisplatin resistance in head and neck cancer
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery and Endocrine Unit, Department of Medicine, University of California San Francisco, 4150 Clement Street 112B, San Francisco, CA 94121, USA
    Arch Otolaryngol Head Neck Surg 132:19-24. 2006
    ..To investigate whether hyaluronan (HA)-CD44 promotes head and neck squamous cell carcinoma (HNSCC) cisplatin resistance and whether HA-CD44 promotes phospholipase C (PLC)-mediated Ca2+ signaling to alter cisplatin sensitivity in HNSCC...
  8. doi request reprint Parotidectomy--Anatomical considerations
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, California
    Clin Anat 25:12-8. 2012
    ..This report will discuss the anatomy of the parotid gland as it pertains to parotid surgery and the avoidance of complications related to this surgery...
  9. pmc CD44 variant isoforms in head and neck squamous cell carcinoma progression
    Steven J Wang
    Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, Veterans Affairs Medical Center, USA
    Laryngoscope 119:1518-30. 2009
    ..The objective of this study was to investigate the role of the CD44 v3, v6, and v10 variant isoforms in head and neck squamous cell carcinoma (HNSCC) tumor progression behaviors...
  10. pmc Reduction of hyaluronan-CD44-mediated growth, migration, and cisplatin resistance in head and neck cancer due to inhibition of Rho kinase and PI-3 kinase signaling
    Carlos Torre
    Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, San Francisco, CA 94121, USA
    Arch Otolaryngol Head Neck Surg 136:493-501. 2010
    ....
  11. ncbi request reprint Oral cavity squamous cell carcinoma in never smokers: analysis of clinicopathologic characteristics and survival
    Megan L Durr
    Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, San Francisco, CA 94115, USA
    Am J Otolaryngol 34:388-93. 2013
    ..To examine the relationship between tobacco smoking history and the clinicopathologic and survival characteristics of patients with oral cavity squamous cell carcinoma (OCSCC)...
  12. doi request reprint Predictors of quality of life after treatment for oral cavity and oropharyngeal carcinoma
    Theresa A Gurney
    Department of Otolaryngology, Head and Neck Surgery, University of California, San Francisco, CA 94115, USA
    Otolaryngol Head Neck Surg 139:262-7. 2008
    ..Treatment for head and neck cancer, including surgery, radiation, and chemotherapy, can impact quality of life...
  13. ncbi request reprint Squamous cell carcinoma of the buccal mucosa: a retrospective analysis of 22 cases
    Doris Lin
    Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco School of Medicine, San Francisco, CA, USA
    Ear Nose Throat J 87:582-6. 2008
    ....
  14. doi request reprint Oral tongue squamous cell carcinoma in never-smokers: analysis of clinicopathologic characteristics and survival
    Megan L Durr
    Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, California 94115, USA
    Otolaryngol Head Neck Surg 149:89-96. 2013
    ..2) To assess the relationship between clinicopathologic characteristics and survival/recurrence in OTSCC...
  15. ncbi request reprint Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma
    Volkert B Wreesmann
    Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, CA, USA
    ORL J Otorhinolaryngol Relat Spec 69:218-25. 2007
    ..This study sought to determine the frequency of FA gene downregulation in sporadic HNSCC...
  16. ncbi request reprint Management of advanced nodal disease following chemoradiation for head and neck squamous cell carcinoma: role of magnetic resonance imaging
    Doris Lin
    Department of Otolaryngology Head and Neck Surgery, UCSF Comprehensive Cancer Center, San Francisco, CA, USA
    J Otolaryngol 36:350-6. 2007
    ..The purpose of this study was to determine the role of magnetic resonance imaging (MRI) to predict persistent nodal disease in head and neck cancer treated with chemoradiation...
  17. doi request reprint Combined modality treatment outcomes for head and neck cancer: comparison of postoperative radiation therapy at academic vs nonacademic medical centers
    Jonathan R George
    Department of Otolaryngology Head and Neck Surgery, School of Medicine, University of California, San Francisco
    JAMA Otolaryngol Head Neck Surg 139:1118-26. 2013
    ..Few data exist to compare outcomes of these populations...
  18. doi request reprint Electrophysiologic facial nerve monitoring during parotidectomy
    David W Eisele
    Division of Head and Neck and Endocrine Surgery, Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, San Francisco, California, USA
    Head Neck 32:399-405. 2010
    ..A review and analysis of the relevant medical literature related to electrophysiologic facial nerve monitoring during parotid surgery are included...
  19. ncbi request reprint TP53 and CDKN2a mutations in never-smoker oral tongue squamous cell carcinoma
    Chase M Heaton
    Department of Otolaryngology Head and Neck Surgery, UCSF Comprehensive Cancer Center, San Francisco, California, U S A
    Laryngoscope 124:E267-73. 2014
    ..To determine the incidence and clinical significance of TP53 and CDKN2a somatic mutations in never smokers with oral tongue squamous cell carcinoma (OTSCC)...
  20. ncbi request reprint Improved outcomes in adjuvant radiotherapy for oral cavity carcinoma at an academic center: A matched-pair analysis
    Jonathan R George
    Department of Otolaryngology Head and Neck Surgery, School of Medicine, University of California, San Francisco, San Francisco, California, U S A
    Laryngoscope 124:1603-8. 2014
    ....
  21. ncbi request reprint Full-thickness skin graft from the groin for coverage of the radial forearm free flap donor site
    Theresa B Kim
    University of California, San Francisco, Department of Otolaryngology Head and Neck Surgery, San Francisco, California 94121, USA
    Am J Otolaryngol 28:325-9. 2007
    ..Our hypothesis is that the use of the full-thickness skin graft decreases morbidity and improves functional and cosmetic outcome at the skin graft donor site while also providing excellent coverage of the forearm donor site...
  22. doi request reprint Role of panendoscopy to identify synchronous second primary malignancies in patients with oral cavity and oropharyngeal squamous cell carcinoma
    Krista Rodriguez-Bruno
    Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, San Francisco, California, USA
    Head Neck 33:949-53. 2011
    ..The purpose of this study was to evaluate the utility of performing "panendoscopy" to identify second primary tumors in these patient populations...
  23. pmc Diagnosis of Bilateral Tonsil Cancers via Staging PET/CT: Case Report and Review
    Edward M Mannina
    Department of Radiation Oncology, University of California San Francisco, 1600 Divisadero Street, P O Box 1708, Suite H 1031, San Francisco, CA 94143, USA
    Int J Otolaryngol 2011:928240. 2011
    ..In addition, PET/CT correctly distinguished pulmonary sarcoidosis from metastatic disease in this patient...
  24. ncbi request reprint Tongue reconstruction: recent advances
    Warris A Bokhari
    Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, San Francisco, California, USA
    Curr Opin Otolaryngol Head Neck Surg 15:202-7. 2007
    ..To examine the recent literature concerning advances in tongue reconstruction after tumor resection...
  25. ncbi request reprint Quality-of-life impact of participation in a head and neck cancer support group
    Kalpesh T Vakharia
    Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, San Francisco, CA, USA
    Otolaryngol Head Neck Surg 136:405-10. 2007
    ..To assess if participation by patients in a head and neck cancer support group improves perceived quality of life (QOL)...
  26. pmc (-)-gossypol inhibits growth and promotes apoptosis of human head and neck squamous cell carcinoma in vivo
    Keith G Wolter
    Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI 48109 1078, USA
    Neoplasia 8:163-72. 2006
    ..Residual tumors remained growth-suppressed for 2 weeks after cessation of (-)-gossypol treatment. Our results demonstrate that (-)-gossypol can inhibit tumor growth in an orthotopic model of aggressive HNSCC...
  27. ncbi request reprint Cell detection in phase-contrast images used for alpha-particle track-etch dosimetry: a semi-automated approach
    Michael B Altman
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
    Phys Med Biol 50:305-18. 2005
    ..When analysing two randomly selected cell dish image databases, the semi-automated method detected 92-94% of all cells and 94-97% of cells with a well-defined cytoplasm and nucleus while reducing human workload by 32-83%...
  28. ncbi request reprint Characterization of an alpha-particle irradiator for individual cell dosimetry measurements
    Steven J Wang
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
    Cancer Biother Radiopharm 18:437-44. 2003
    ..Additionally, we describe the sources of uncertainty associated with this experiment, including the cell dish repositioning and cell migration during scanning and irradiation...