Hsing Wen Wang

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome
    Hsing Wen Wang
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Cancer Res 64:7553-61. 2004
  2. ncbi request reprint Broadband reflectance measurements of light penetration, blood oxygenation, hemoglobin concentration, and drug concentration in human intraperitoneal tissues before and after photodynamic therapy
    Hsing Wen Wang
    University of Pennsylvania, Department of Physics and Astronomy, 209 South 33rd Street, Philadelphia, Pennsylvania 19104 6396, USA
    J Biomed Opt 10:14004. 2005
  3. pmc Fluence rate-dependent intratumor heterogeneity in physiologic and cytotoxic responses to Photofrin photodynamic therapy
    Theresa M Busch
    Department of Radiation Oncology, School of Medicine, University of Pennsylvania, B13 Anatomy and Chemistry, 3620 Hamilton Walk, Philadelphia, PA 19104 6072, USA
    Photochem Photobiol Sci 8:1683-93. 2009
  4. ncbi request reprint In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates
    Michael Solonenko
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia 19104, USA
    Phys Med Biol 47:857-73. 2002
  5. ncbi request reprint Noninvasive monitoring of murine tumor blood flow during and after photodynamic therapy provides early assessment of therapeutic efficacy
    Guoqiang Yu
    Department of Physics and Astronomy, School of Arts and Sciences, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Clin Cancer Res 11:3543-52. 2005
  6. ncbi request reprint A phase II trial of intraperitoneal photodynamic therapy for patients with peritoneal carcinomatosis and sarcomatosis
    Stephen M Hahn
    Department of Radiation Oncology, Division of Gynecologic Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Clin Cancer Res 12:2517-25. 2006
  7. ncbi request reprint Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis
    Hsing Wen Wang
    University of Pennsylvania, Department of Physics, Philadelphia, Pennsylvania, USA
    J Biomed Opt 12:034023. 2007
  8. ncbi request reprint Effect of photosensitizer dose on fluence rate responses to photodynamic therapy
    Hsing Wen Wang
    Department of Radiation Oncology, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Photochem Photobiol 83:1040-8. 2007
  9. pmc Increasing damage to tumor blood vessels during motexafin lutetium-PDT through use of low fluence rate
    Theresa M Busch
    Department of Radiation Oncology, School of Medicine, University of Pennsylvania Philadelphia, Pennsylvania 19104, USA
    Radiat Res 174:331-40. 2010

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome
    Hsing Wen Wang
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Cancer Res 64:7553-61. 2004
    ..These data suggest that monitoring of PDT-induced changes in tumor oxygenation may be a valuable prognostic indicator...
  2. ncbi request reprint Broadband reflectance measurements of light penetration, blood oxygenation, hemoglobin concentration, and drug concentration in human intraperitoneal tissues before and after photodynamic therapy
    Hsing Wen Wang
    University of Pennsylvania, Department of Physics and Astronomy, 209 South 33rd Street, Philadelphia, Pennsylvania 19104 6396, USA
    J Biomed Opt 10:14004. 2005
    ..These results provide benchmark in-vivo tissue optical property data, and demonstrate the feasibility of in-situ measurements during clinical PDT treatments...
  3. pmc Fluence rate-dependent intratumor heterogeneity in physiologic and cytotoxic responses to Photofrin photodynamic therapy
    Theresa M Busch
    Department of Radiation Oncology, School of Medicine, University of Pennsylvania, B13 Anatomy and Chemistry, 3620 Hamilton Walk, Philadelphia, PA 19104 6072, USA
    Photochem Photobiol Sci 8:1683-93. 2009
    ..This research suggests that the benefits of low-fluence-rate PDT are mediated in part by a reduction in intratumor heterogeneity in hypoxic, vascular and cytotoxic responses...
  4. ncbi request reprint In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates
    Michael Solonenko
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia 19104, USA
    Phys Med Biol 47:857-73. 2002
    ..This class of in situ optical property measurement may be desirable to individualize PDT drug and light delivery...
  5. ncbi request reprint Noninvasive monitoring of murine tumor blood flow during and after photodynamic therapy provides early assessment of therapeutic efficacy
    Guoqiang Yu
    Department of Physics and Astronomy, School of Arts and Sciences, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Clin Cancer Res 11:3543-52. 2005
    ..To monitor tumor blood flow noninvasively during photodynamic therapy (PDT) and to correlate flow responses with therapeutic efficacy...
  6. ncbi request reprint A phase II trial of intraperitoneal photodynamic therapy for patients with peritoneal carcinomatosis and sarcomatosis
    Stephen M Hahn
    Department of Radiation Oncology, Division of Gynecologic Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Clin Cancer Res 12:2517-25. 2006
    ..The primary objectives of this phase II study were to determine the efficacy and toxicities of i.p. photodynamic therapy in patients with peritoneal carcinomatosis and sarcomatosis...
  7. ncbi request reprint Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis
    Hsing Wen Wang
    University of Pennsylvania, Department of Physics, Philadelphia, Pennsylvania, USA
    J Biomed Opt 12:034023. 2007
    ..These results further demonstrate the potential of in vivo DRS measurements in clinical PDT...
  8. ncbi request reprint Effect of photosensitizer dose on fluence rate responses to photodynamic therapy
    Hsing Wen Wang
    Department of Radiation Oncology, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Photochem Photobiol 83:1040-8. 2007
    ..Clinical confirmation and application of these results will be possible through use of minimally invasive oxygen and photosensitizer monitoring technologies, which are currently under development...
  9. pmc Increasing damage to tumor blood vessels during motexafin lutetium-PDT through use of low fluence rate
    Theresa M Busch
    Department of Radiation Oncology, School of Medicine, University of Pennsylvania Philadelphia, Pennsylvania 19104, USA
    Radiat Res 174:331-40. 2010
    ..Further study of low fluence rate as a means to improve responses to PDT under conditions designed to predominantly damage vasculature is warranted...