Jessica Wang-Rodriguez

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Computerized decision support system for intraoperative analysis of margin status in breast conservation therapy
    Manuel E Ruidiaz
    Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA
    ISRN Surg 2012:546721. 2012
  2. pmc Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes
    Bj rn Tyrberg
    UCSD Cancer Center, La Jolla, CA 92037 0912, USA
    BMC Endocr Disord 2:2. 2002
  3. ncbi request reprint Immune response to blood transfusion invery-low-birthweight infants
    J Wang-Rodriguez
    University of California, San Diego, Medical Center, Hillcrest, San Diego, California, USA
    Transfusion 40:25-34. 2000
  4. ncbi request reprint Male breast carcinoma: correlation of ER, PR, Ki-67, Her2-Neu, and p53 with treatment and survival, a study of 65 cases
    Jessica Wang-Rodriguez
    Department of Pathology, University of California, San Diego, School of Medicine, La Jolla 92093, USA
    Mod Pathol 15:853-61. 2002
  5. pmc Elevated osteopontin and thrombospondin expression identifies malignant human breast carcinoma but is not indicative of metastatic status
    Jessica Wang-Rodriguez
    Department of Pathology, University of California, San Diego, La Jolla, USA
    Breast Cancer Res 5:R136-43. 2003
  6. ncbi request reprint Gefitinib inhibition of drug resistance to doxorubicin by inactivating ABCG2 in thyroid cancer cell lines
    Jay Patrick Lopez
    Department of Surgery, VA San Diego Healthcare System, and Department of Radiology, University of California, San Diego, Biomedical Sciences Bldg, Room 1202, Mail Code 0612, 9500 Gilman Dr, La Jolla, CA 92093 0612, USA
    Arch Otolaryngol Head Neck Surg 133:1022-7. 2007
  7. pmc Nicotine promotes acquisition of stem cell and epithelial-to-mesenchymal properties in head and neck squamous cell carcinoma
    Michael Andrew Yu
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of California San Diego, La Jolla, CA, USA
    PLoS ONE 7:e51967. 2012
  8. pmc Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt
    Selena Z Kuo
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of California, San Diego, San Diego, CA, USA
    BMC Cancer 12:556. 2012
  9. pmc Cigarette smoke promotes drug resistance and expansion of cancer stem cell-like side population
    Yi An
    Division of Head and Neck Surgery, Department of Surgery, University of California San Diego, San Diego, California, United States of America
    PLoS ONE 7:e47919. 2012
  10. pmc EGFR kinase promotes acquisition of stem cell-like properties: a potential therapeutic target in head and neck squamous cell carcinoma stem cells
    Eric L Abhold
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of California San Diego, San Diego, California, United States of America
    PLoS ONE 7:e32459. 2012

Collaborators

Detail Information

Publications42

  1. pmc Computerized decision support system for intraoperative analysis of margin status in breast conservation therapy
    Manuel E Ruidiaz
    Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA
    ISRN Surg 2012:546721. 2012
    ....
  2. pmc Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes
    Bj rn Tyrberg
    UCSD Cancer Center, La Jolla, CA 92037 0912, USA
    BMC Endocr Disord 2:2. 2002
    ..An increase of Ogg1 in islet cell mitochondria is consistent with a model in which hyperglycemia and consequent increased beta-cell oxidative metabolism lead to DNA damage and the induction of Ogg1 expression...
  3. ncbi request reprint Immune response to blood transfusion invery-low-birthweight infants
    J Wang-Rodriguez
    University of California, San Diego, Medical Center, Hillcrest, San Diego, California, USA
    Transfusion 40:25-34. 2000
    ..Allogeneic blood transfusion is common in the treatment of neonatal anemia of prematurity or anemia due to multiple phlebotomies. The immune response of neonates to passenger leukocytes from allogeneic red cells was investigated...
  4. ncbi request reprint Male breast carcinoma: correlation of ER, PR, Ki-67, Her2-Neu, and p53 with treatment and survival, a study of 65 cases
    Jessica Wang-Rodriguez
    Department of Pathology, University of California, San Diego, School of Medicine, La Jolla 92093, USA
    Mod Pathol 15:853-61. 2002
    ....
  5. pmc Elevated osteopontin and thrombospondin expression identifies malignant human breast carcinoma but is not indicative of metastatic status
    Jessica Wang-Rodriguez
    Department of Pathology, University of California, San Diego, La Jolla, USA
    Breast Cancer Res 5:R136-43. 2003
    ..The aim of the present study was to examine the cellular distribution of these molecules in human breast tissue and to determine whether the relative expression level of these three genes is associated with human breast tumor metastasis...
  6. ncbi request reprint Gefitinib inhibition of drug resistance to doxorubicin by inactivating ABCG2 in thyroid cancer cell lines
    Jay Patrick Lopez
    Department of Surgery, VA San Diego Healthcare System, and Department of Radiology, University of California, San Diego, Biomedical Sciences Bldg, Room 1202, Mail Code 0612, 9500 Gilman Dr, La Jolla, CA 92093 0612, USA
    Arch Otolaryngol Head Neck Surg 133:1022-7. 2007
    ....
  7. pmc Nicotine promotes acquisition of stem cell and epithelial-to-mesenchymal properties in head and neck squamous cell carcinoma
    Michael Andrew Yu
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of California San Diego, La Jolla, CA, USA
    PLoS ONE 7:e51967. 2012
    ..Further characterization of such pathways remains a promising avenue for the understanding and treatment of tobacco-related cancers...
  8. pmc Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt
    Selena Z Kuo
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of California, San Diego, San Diego, CA, USA
    BMC Cancer 12:556. 2012
    ..In our study we sought to determine the effects of salinomycin on head and neck squamous cell carcinoma (HNSCC) stem cells...
  9. pmc Cigarette smoke promotes drug resistance and expansion of cancer stem cell-like side population
    Yi An
    Division of Head and Neck Surgery, Department of Surgery, University of California San Diego, San Diego, California, United States of America
    PLoS ONE 7:e47919. 2012
    ..These findings underscore the importance of smoking cessation following a diagnosis of cancer, and elucidate the mechanisms of continued smoking that may be detrimental to treatment...
  10. pmc EGFR kinase promotes acquisition of stem cell-like properties: a potential therapeutic target in head and neck squamous cell carcinoma stem cells
    Eric L Abhold
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of California San Diego, San Diego, California, United States of America
    PLoS ONE 7:e32459. 2012
    ..Drugs that target EGFR, perhaps administered in combination with conventional chemotherapy, might be an effective treatment for HNSCC...
  11. ncbi request reprint STI-571 (Gleevec) potentiates the effect of cisplatin in inhibiting the proliferation of head and neck squamous cell carcinoma in vitro
    Jessica Wang-Rodriguez
    VA San Diego Healthcare System, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Laryngoscope 116:1409-16. 2006
    ..The objective of this study was to determine whether STI-571 (Gleevec; imatinib mesylate) could sensitize established head and neck squamous cell carcinoma (HNSCC) cell lines to the effects of cisplatin...
  12. ncbi request reprint Gleevec suppresses p63 expression in head and neck squamous cell carcinoma despite p63 activation by DNA-damaging agents
    Weg M Ongkeko
    Division of Head and Neck Surgery, Department of Surgery, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Laryngoscope 116:1390-6. 2006
    ....
  13. ncbi request reprint Gefitinib (Iressa) potentiates the effect of ionizing radiation in thyroid cancer cell lines
    Jay Patrick Lopez
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of California, San Diego, San Diego, California 92093, USA
    Laryngoscope 118:1372-6. 2008
    ..To determine whether inactivation of epidermal growth factor receptor (EGFR) kinase activity will sensitize thyroid cancer cell lines to ionizing radiation-induced death...
  14. pmc Early human prostate adenocarcinomas harbor androgen-independent cancer cells
    Rita R Fiñones
    Department of Mechanical and Aerospace Engineering, University of California San Diego, La Jolla, California, United States of America
    PLoS ONE 8:e74438. 2013
    ....
  15. pmc The onco-embryonic antigen ROR1 is expressed by a variety of human cancers
    Suping Zhang
    Moores UCSD Cancer Center, University of California San Diego, 3855 Health Sciences Dr 0820, La Jolla, CA 92093, USA
    Am J Pathol 181:1903-10. 2012
    ....
  16. ncbi request reprint Enhanced touch preps improve the ease of interpretation of intraoperative breast cancer margins
    Sarah L Blair
    Department of Surgery and Pathology, University of California San Diego, La Jolla, California 92093 0987, USA
    Am Surg 73:973-6. 2007
    ..The immunofluorescence stains may help the pathologist to identify cancer cells in fresh breast tissue and limit breast re-excisions in the future...
  17. ncbi request reprint Expression signatures that correlated with Gleason score and relapse in prostate cancer
    Marina Bibikova
    Illumina, Inc, 9885 Towne Centre Drive, San Diego, CA 92121, USA
    Genomics 89:666-72. 2007
    ..007). These results suggest that the approach we used is effective for expression profiling in heterogeneous FFPE tissues for cancer diagnosis/prognosis biomarker discovery and validation...
  18. doi request reprint Quantitative comparison of surgical margin histology following excision with traditional electrosurgery and a low-thermal-injury dissection device
    Manuel E Ruidiaz
    Department of Bioengineering, University of California, San Diego UCSD, La Jolla, California, USA
    J Surg Oncol 104:746-54. 2011
    ..This study is the first to examine in vivo the effect of thermal injury in breast conservation pathology in a direct comparison of traditional electrosurgery and an alternative low-thermal-injury device...
  19. doi request reprint p73 expression and function in vestibular schwannoma
    Zana K Ahmad
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of California, San Diego, La Jolla, CA 92093 0612, USA
    Arch Otolaryngol Head Neck Surg 135:662-9. 2009
    ....
  20. pmc Quantitative automated image analysis system with automated debris filtering for the detection of breast carcinoma cells
    David T Martin
    Department of Electrical and Computer Engineering, University of California San Diego, San Diego, CA 92161, USA
    Acta Cytol 55:271-80. 2011
    ..To develop an intraoperative method for margin status evaluation during breast conservation therapy (BCT) using an automated analysis of imprint cytology specimens...
  21. ncbi request reprint EGFR regulates the side population in head and neck squamous cell carcinoma
    Jocelyn S Chen
    Division of Head and Neck Surgery, Department of Surgery, University of California, San Diego, San Diego, California 92093, USA
    Laryngoscope 116:401-6. 2006
    ..To identify the presence of side population (SP) cells in established head and neck squamous carcinoma cell (HNSCC) lines and to determine the role of EGFR in the regulation of the side population of these cells...
  22. pmc Automated microscopy to evaluate surgical specimens via touch prep in breast cancer
    Maria Jose Cortes-Mateos
    Moores Cancer Center, University of California San Diego, San Diego, CA 92093 0987, USA
    Ann Surg Oncol 16:709-20. 2009
    ..An automated image screening process has been developed to discern cancer cells from normal epithelial cells. This technique is based on cellularity of the imprint specimen and does not require expertise in cytopathology...
  23. doi request reprint Quantitative expression profiling of RNA from formalin-fixed, paraffin-embedded tissues using randomly assembled bead arrays
    Marina Bibikova
    Illumina Inc, San Diego, CA, USA
    Methods Mol Biol 439:159-77. 2008
    ..Using the DASL Assay, gene expression analyses can be performed on routinely stored tumor specimens from patients with known outcomes...
  24. doi request reprint Activation of PDGFR and EGFR promotes the acquisition of a stem cell-like phenotype in schwannomas
    David Yi
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of California, San Diego, California, USA
    Otol Neurotol 33:1640-7. 2012
    ....
  25. doi request reprint EGF and bFGF promote invasion that is modulated by PI3/Akt kinase and Erk in vestibular schwannoma
    Katherine J Blair
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of California San Diego and the VA San Diego Healthcare System, San Diego, California, USA
    Otol Neurotol 32:308-14. 2011
    ..We aimed to determine the role of the growth factors EGF, bFGF, and the hormone, Epo, in promoting such invasive behavior in VS, as well as their mechanisms of action...
  26. pmc Parathyroid hormone related-protein promotes epithelial-to-mesenchymal transition in prostate cancer
    Weg M Ongkeko
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of California San Diego, La Jolla, California, United States of America
    PLoS ONE 9:e85803. 2014
    ..Thus, continued efforts to elucidate the pathways involved in PTHrP-induced EMT as well as to develop ways to specifically target PTHrP signaling may lead to more effective therapies for prostate cancer. ..
  27. doi request reprint Genomic profiling of 766 cancer-related genes in archived esophageal normal and carcinoma tissues
    Jing Chen
    Illumina Inc, San Diego, CA 92121, USA
    Int J Cancer 122:2249-54. 2008
    ..Taken together, our results demonstrated the utility of the BeadArray technology for high-throughput genetic analysis in FFPE tumor tissues and provided a detailed genetic profiling of cancer-related genes in human esophageal cancer...
  28. ncbi request reprint Gastrointestinal stromal tumors express ras oncogene: a potential role for diagnosis and treatment
    Sarah L Blair
    Department of Surgery, University of California at San Diego, 92093 0987, USA
    Arch Surg 140:543-7; discussion 547-8. 2005
    ..There is some evidence that phosphorylation of these receptors leads to a cascade that may activate the ras/mitogen-activated protein kinase pathway, which may, in turn, allow other oncogenes to become active...
  29. pmc Recombinant human erythropoietin promotes the acquisition of a malignant phenotype in head and neck squamous cell carcinoma cell lines in vitro
    Eric Abhold
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of California, San Diego, San Diego, CA, USA
    BMC Res Notes 4:553. 2011
    ..abstract:..
  30. pmc ROR1 is expressed in human breast cancer and associated with enhanced tumor-cell growth
    Suping Zhang
    Moores UCSD Cancer Center, University of California San Diego, La Jolla, California, United States of America
    PLoS ONE 7:e31127. 2012
    ..This study demonstrates that ROR1 is expressed in human breast cancers and has biological and clinical significance, indicating that it may be a potential target for breast cancer therapy...
  31. doi request reprint Motility induction in breast carcinoma by mammary epithelial laminin 332 (laminin 5)
    Philip M Carpenter
    Department of Pathology and Laboratory Medicine, University of California, Orange, CA 92868, USA
    Mol Cancer Res 7:462-75. 2009
    ....
  32. pmc A sensitive array-based assay for identifying multiple TMPRSS2:ERG fusion gene variants
    Qing Lu
    Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA
    Nucleic Acids Res 36:e130. 2008
    ..The assay should facilitate clinical and basic studies for fusion gene screening in clinical specimens, as it can be readily adapted to include multiple gene loci...
  33. pmc Rare case of a primary non-dural central nervous system low grade B-cell lymphoma and literature review
    Antonios Papanicolau-Sengos
    Department of Pathology, University of California San Diego School of Medicine and Veteran Administration Medical Center of San Diego, 9500 Gilman Drive 9113, La Jolla, CA 92093 9113, USA
    Int J Clin Exp Pathol 5:89-95. 2012
    ..This is the first reported case of a primary CNS MZBCL with flow cytometric analysis. A review of literature on this rare entity is also included...
  34. ncbi request reprint Two-dimensional transcriptome profiling: identification of messenger RNA isoform signatures in prostate cancer from archived paraffin-embedded cancer specimens
    Hai Ri Li
    Department of Cellular and Molecular Medicine, San Diego Supercomputer Center, University of California, San Diego, La Jolla 92093 0651, USA
    Cancer Res 66:4079-88. 2006
    ....
  35. ncbi request reprint CD20-positive plasmablastic lymphoma with excellent response to bortezomib combined with rituximab
    Min Yan
    Moores Cancer Center, University of California San Diego Health System, La Jolla, CA, USA
    Eur J Haematol 93:77-80. 2014
    ..Here, we report a near-complete response of one patient with relapsed PBL following treatment with a non-cytotoxic regimen containing bortezomib, rituximab, and dexamethasone...
  36. pmc Oncologic safety of skin-sparing and nipple-sparing mastectomy: a discussion and review of the literature
    Christopher Tokin
    Department of Surgery, University of San Diego, San Diego, CA 92103, USA
    Int J Surg Oncol 2012:921821. 2012
    ..In addition, this paper will discuss the oncologic importance of margin status and type of mastectomy as it pertains to risk of local recurrence and relative need for adjuvant therapy...
  37. ncbi request reprint Expression of protein tyrosine kinases in head and neck squamous cell carcinomas
    Weg M Ongkeko
    Department of Surgery, Division of Head and Neck, Surgery, University of California, San Diego, CA 92161, USA
    Am J Clin Pathol 124:71-6. 2005
    ..None of the kinase expressions correlated with disease-free survival. The expression of the kinases raises the possibility of treatment of HNSCC by tyrosine and serine-threonine kinase inhibitors...
  38. pmc Diagnosis of prostate cancer using differentially expressed genes in stroma
    Zhenyu Jia
    Department of Pathology and Laboratory Medicine, University of California, Irvine, CA, USA
    Cancer Res 71:2476-87. 2011
    ....
  39. ncbi request reprint The signaling adapter protein PINCH is up-regulated in the stroma of common cancers, notably at invasive edges
    Jessica Wang-Rodriguez
    Department of Pathology, University of California, San Diego, La Jolla 92093, USA
    Cancer 95:1387-95. 2002
    ..Because no information is available regarding its expression in vivo in human tissues, this study evaluated the distribution and abundance of PINCH in patients with breast, prostate, lung, colon, and skin carcinomas...
  40. doi request reprint Laminin 5 expression in metaplastic breast carcinomas
    Philip M Carpenter
    The Department of Pathology and Laboratory Medicine, The University of California, Orange, CA 92868, USA
    Am J Surg Pathol 32:345-53. 2008
    ..Further study of other basal-like tumors for laminin 5 expression is warranted to determine the usefulness of laminin 5 in their diagnosis...
  41. ncbi request reprint Gene expression profiles in formalin-fixed, paraffin-embedded tissues obtained with a novel assay for microarray analysis
    Marina Bibikova
    Illumina, Inc, San Diego, CA 92161, USA
    Clin Chem 50:2384-6. 2004
  42. pmc Profiling alternatively spliced mRNA isoforms for prostate cancer classification
    Chaolin Zhang
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    BMC Bioinformatics 7:202. 2006
    ..Here, we investigate the advantage of using splice isoforms, which couple transcriptional and splicing regulation, for cancer classification...