Research Topics
| Thomas J WalshSummaryAffiliation: University of California Country: USA Publications
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Publications
Bilateral but not unilateral testicular hypotrophy predicts for severe impairment of semen quality in men with varicocele undergoing infertility evaluationAlex K Wu
Department of Urology, University of California, San Francisco, School of Medicine, San Francisco, California 94143 1695, USA
Urology 71:1114-8. 2008..We investigated the relationship between testicular hypotrophy and poor semen quality in infertile men with varicoceles. We hypothesized that bilateral hypotrophy is required before the semen quality is severely impaired...
Antenatal hydronephrosis and the risk of pyelonephritis hospitalization during the first year of lifeThomas J Walsh
Department of Urology, University of Washington School of Medicine, Seattle, Washington, USA
Urology 69:970-4. 2007..To assess the risk of hospitalization for pyelonephritis within the first year of life among infants with and without antenatal hydronephrosis...
Differences in the clinical characteristics of primarily and secondarily infertile men with varicoceleThomas J Walsh
Department of Urology, University of California, San Francisco, California 94143 1695, USA
Fertil Steril 91:826-30. 2009..To compare the clinical characteristics of primarily and secondarily infertile men with varicocele...
Racial differences among boys with testicular germ cell tumors in the United StatesThomas J Walsh
Department of Urology, University of California San Francisco, San Francisco, California 94143 1695, USA
J Urol 179:1961-5. 2008..We hypothesize that recent diversification of race data by cancer registries may allow for more accurate racial classification, and that there are racial differences in the incidence of testicular germ cell tumors in prepubertal boys...
Ureteroscopic treatment of upper-tract urothelial lesions: a novel techniqueThomas J Walsh
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
J Endourol 21:718-20. 2007..This technique may make it easier to obtain tissue from the urothelium and reduce operative times...
Spermatoceles in adults: when does size matter?Thomas J Walsh
Department of Urology, University of California, San Francisco, 1600 Divisadero St, Box 1695, San Francisco, CA 94143 1695, USA
Arch Androl 53:345-8. 2007..Men in this series appear to tolerate spermatoceles for a relatively long period of time. Once they seek excision, spermatoceles have grown to roughly the size of a normal testicle and men are bothered both by pain and mass symptoms...
Prepubertal orchiopexy for cryptorchidism may be associated with lower risk of testicular cancerThomas J Walsh
Department of Urology, University of California San Francisco, San Francisco, California 94143 1695, USA
J Urol 178:1440-6; discussion 1446. 2007..We hypothesize that early orchiopexy is protective against subsequent development of testicular germ cell cancer...
Increased risk of high-grade prostate cancer among infertile menThomas J Walsh
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195 6510, USA
Cancer 116:2140-7. 2010..In the current study, the authors examined the subsequent occurrence of prostate cancer in a cohort of men evaluated for infertility to determine whether male infertility is a risk factor for prostate cancer...
Who is the 40-year-old virgin and where did he/she come from? Data from the National Survey of Family GrowthMichael L Eisenberg
Department of Urology, University of California, San Francisco, CA 94143 0738, USA
J Sex Med 6:2154-61. 2009..Individuals who have not engaged in sexual activity may theoretically have diminished overall quality of life, as recent evidence suggests that sexual activity may be related to overall health status in adults...
Racial disparities in erectile dysfunction among participants in the California Men's Health StudyJames F Smith
University of California, San Francisco, Department of Urology, San Francisco, CA 94143, USA
J Sex Med 6:3433-9. 2009..The burden of erectile dysfunction (ED) among different racial and ethnic groups is unclear, in part, because prior studies have not included all four major racial and ethnic groups in the same population-based sample...
Socioeconomic disparities in the use and success of fertility treatments: analysis of data from a prospective cohort in the United StatesJames F Smith
Department of Urology, University of California, San Francisco, 1600 Divisadero Street, Box 1695, San Francisco, CA 94143 1695, USA
Fertil Steril 96:95-101. 2011..To determine the effect of income, education, and race on the use and outcomes of infertility care...
Increased risk of testicular germ cell cancer among infertile menThomas J Walsh
Department of Urology, University of Washington, School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195 6510
Arch Intern Med 169:351-6. 2009..Confirmation of this risk in a large US cohort of at-risk patients is lacking. This study explored the association between male infertility and subsequent development of testicular cancer in a US-based cohort...
Surgical techniques for the management of male infertilityNatalya A Lopushnyan
Department of Urology, University of Washington, Seattle, 98195, USA
Asian J Androl 14:94-102. 2012..Clinicians treating infertility should advocate for couple-based therapy, and require that both partners have a thorough evaluation and an informed discussion before undergoing specific surgical therapies...
Men who seek infertility care may not represent the general U.S. population: data from the National Survey of Family GrowthJames M Hotaling
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
Urology 79:123-7. 2012..To examine the National Survey of Family Growth to identify differences in the characteristics of men who did and did not seek infertility care to determine whether such men are representative of the U.S. population...
The kinetics of the return of motile sperm to the ejaculate after vasectomy reversalGlen Yang
Department of Urology, Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, 1600 Divisadero Street, San Francisco, CA 94143, USA
J Urol 177:2272-6. 2007..We hypothesize that there are predictors of time to patency after reversal that are valuable for patient counseling and intraoperative decision making in cases of advanced maternal age...
Sexual, marital, and social impact of a man's perceived infertility diagnosisJames F Smith
Department of Urology, University of California, San Francisco, CA 94143, USA
J Sex Med 6:2505-15. 2009..Male factor infertility is a relatively common problem. This diagnosis may increase sexual, marital, and relationship strain in male partners of infertile couples...
Racial differences in vasectomy utilization in the United States: data from the national survey of family growthMichael L Eisenberg
Department of Urology, University of California, San Francisco, California 94143 0738, USA
Urology 74:1020-4. 2009..In this analysis, we examined differences in vasectomy rates according to factors such as race and socioeconomic status...
A novel application of 1H magnetic resonance spectroscopy: non-invasive identification of spermatogenesis in men with non-obstructive azoospermiaDavid S Aaronson
Department of Urology, University of California San Francisco, Ambulatory Care Center, Suite A633, San Francisco, CA 94117, USA
Hum Reprod 25:847-52. 2010..This study sought to identify metabolic signatures associated with various histological states of spermatogenesis in infertile men...
Raw and test-thaw semen parameters after cryopreservation among men with newly diagnosed cancerJames M Hotaling
Department of Urology, University of Washington, Seattle, Washington 98195, USA
Fertil Steril 99:464-9. 2013..To characterize sperm parameters from thawed semen samples of men with different cancers who cryopreserved semen before oncologic therapy...
Fecundity and sex ratio of offspring in an infertile cohortMichael L Eisenberg
Department of Urology, University of California, San Francisco, California, USA
Fertil Steril 96:833-6. 2011..To determine whether male and female subfecundity is associated with the gender ratio...
Risk factors for emotional and relationship problems in Peyronie's diseaseJames F Smith
University of California, San Francisco Urology, San Francisco, CA, USA
J Sex Med 5:2179-84. 2008..Peyronie's disease (PD) occurs in 3-9% of all men. Little is known regarding the specific psychological or emotional disruptions to sexuality associated with PD...
Use of viscoelastic solution to improve visualization during urologic microsurgery: evaluation of patency after vasovasostomyMichael L Eisenberg
Department of Urology, University of California, San Francisco, School of Medicine, San Francisco, California, USA
Urology 73:134-6. 2009..Commonly used in ophthalmic surgery, we evaluated whether it could improve the optics during urologic microsurgery without adversely affecting outcomes...
Wet heat exposure: a potentially reversible cause of low semen quality in infertile menShai Shefi
Department of Urology, University of California San Francisco, San Francisco, California 94143 1695, USA
Int Braz J Urol 33:50-6; discussion 56-7. 2007..To evaluate the recovery of semen quality in a cohort of infertile men after known hyperthermic exposure to hot tubs, hot baths or whirlpool baths...
Male reproductive health and prostate cancer riskThomas J Walsh
Department of Urology, University of Washington School of Medicine, Seattle, Washington, USA
Curr Opin Urol 21:506-13. 2011....
Meta-analysis: does lidocaine gel before flexible cystoscopy provide pain relief?David S Aaronson
UCSF Medical Center, Department of Urology, Ambulatory Care Center, Suite A633, San Francisco, CA 94117, USA
BJU Int 104:506-9; discussion 509-10. 2009....
Incidence of testicular germ cell cancers in U.S. children: SEER program experience 1973 to 2000Thomas J Walsh
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
Urology 68:402-5; discussion 405. 2006..We analyzed a population-based cohort to determine whether the incidence trends of prepubertal testicular germ cell tumors have risen similarly to those seen in adult testicular tumors...
Perceived negative consequences of donor gametes from male and female members of infertile couplesMichael L Eisenberg
Department of Urology, University of California San Francisco, San Francisco, California 94143 0738, USA
Fertil Steril 94:921-6. 2010..To determine the views toward donor sperm and eggs of both men and women. The use of donor sperm or ova becomes an option for some infertile couples...
A noninvasive, motility independent, sperm sorting method and technology to identify and retrieve individual viable nonmotile sperm for intracytoplasmic sperm injectionMaurice M Garcia
Department of Urology, University of California San Francisco, San Francisco, California 94143, USA
J Urol 184:2466-72. 2010..We assessed the ability of optoelectronic tweezers to distinguish viable from nonviable individual nonmotile human sperm...
Ejaculatory duct manometry in normal men and in patients with ejaculatory duct obstructionMichael L Eisenberg
Department of Urology, University of California San Francisco, San Francisco, California 94143 1695, USA
J Urol 180:255-60; discussion 260. 2008..We describe what is to our knowledge a new hydraulic test and report its ability to identify physical and functional ejaculatory duct obstruction...
The relationship between isolated teratozoospermia and clinical pregnancy after in vitro fertilization with or without intracytoplasmic sperm injection: a systematic review and meta-analysisJames M Hotaling
Department of Urology, University of Washington, Seattle, Washington 98195, USA
Fertil Steril 95:1141-5. 2011..A total of 31 studies were identified, and 4 met the inclusion criteria. Isolated teratozoospermia was not associated with a statistically significantly decreased probability of pregnancy with assisted reproduction...
Male infertility: a risk factor for testicular cancerJames M Hotaling
Department of Urology, University of Washington School of Medicine, Seattle, WA 98195, USA
Nat Rev Urol 6:550-6. 2009..The elucidation of the pathways underlying this association will enable development of appropriate tests that will identify men susceptible to development of TGCT and other testicular pathologies...
Isolated infection of a decommissioned penile prosthesis reservoir with Actinomyces neuiiRyan S Hsi
Department of Urology, University of Washington School of Medicine, Seattle, WA 98195, USA
J Sex Med 8:923-6. 2011..The most serious complication with IPPs is infection, with the reported incidence after primary placement 1% to 3% and after revision surgery 8% to 18%...
Effect of BMI on primary treatment of prostate cancerBenjamin J Davies
Department of Urology, Urology Outcomes Research Group, University of California San Francisco Comprehensive Cancer Center, University of California, San Francisco 94143 1695, USA
Urology 72:406-11. 2008..This study was designed to assess the relationship between body mass index (BMI) and treatment patterns of prostate cancer patients...
Ejaculatory duct obstructionJames F Smith
Department of Urology, University of California, San Francisco, 1600 Divisadero Street, San Francisco, CA 94143, USA
Urol Clin North Am 35:221-7, viii. 2008..Using an evidence-based approach, this article reviews how best to approach the diagnosis and treatment of ejaculatory duct obstruction...
The genetics of male infertilityThomas J Walsh
Department of Urology, University of California San Francisco, San Francisco, California, USA
Semin Reprod Med 27:124-36. 2009..Indeed, as our understanding of genetic infertility matures, so too will the importance and complexity of genetic counseling and testing for patients who use assisted reproduction...
Candida bloodstream infections in hemodialysis recipientsVasilios Pyrgos
Section of Infectious Diseases, Washington Hospital Center, Washington, DC 20010, USA
Med Mycol 47:463-7. 2009..9% vs. 7.8%; P<0.0001). Candidemia in hemodialysis recipients is frequently caused by non-C. albicansCandida species, is associated with TPN and dialysis via a vascular catheter (vs. shunt or fistula) and carries a high mortality rate...
Erectile Dysfunction Is Not Independently Associated with Cardiovascular Death: Data from the Vitamins and Lifestyle (VITAL) StudyJames M Hotaling
Department of Urology, University of Washington, Seattle, WA, USA Department of Epidemiology, University of Washington, Seattle, WA, USA Fred Hutchinson Cancer Research Center, Seattle, WA, USA
J Sex Med 9:2104-10. 2012..Erectile dysfunction is not independently associated with cardiovascular death: Data from the Vitamins and Lifestyle (VITAL) study. J Sex Med 2012;9:2104-2110...
A sensitive and specific method for measurement of multiple retinoids in human serum with UHPLC-MS/MSSamuel L M Arnold
Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA
J Lipid Res 53:587-98. 2012..11-cisRA and 4OH-RA were not detected in human serum. The high sensitivity of the MS/MS method combined with the UHPLC separation power allowed detection of endogenous 9-cisRA and 4oxo-atRA for the first time in human serum...
Performance of total testosterone measurement to predict free testosterone for the biochemical evaluation of male hypogonadismBradley D Anawalt
Department of Medicine, University of Washington and Geriatric Research, Seattle, Washington 98195, USA
J Urol 187:1369-73. 2012..We determined the performance of total testosterone measurement as a test to identify men with normal vs low free testosterone...
Primary treatment of zygomycosis with liposomal amphotericin B: analysis of 28 casesShmuel Shoham
Section of Infectious Diseases, Department of Medicine, Washington Hospital Center, Washington, DC, USA
Med Mycol 48:511-7. 2010....
The potential of hormones and selective oestrogen receptor modulators in preventing voiding dysfunction in ratsKavirach Tantiwongse
Knuppe Molecular Urology Laboratory, Department of Urology, University of California San Francisco, San Francisco, CA 94143 0738, USA
BJU Int 102:242-6. 2008..To investigate whether oestrogen, selective oestrogen receptor modulators (SERMs), and growth hormone (GH) can prevent the development of voiding dysfunction in a postpartum postmenopausal rat model of voiding dysfunction...
Successful treatment of a child with posttraumatic necrotizing fasciitis caused by Apophysomyces elegans: case report and review of literatureFaisal N Kordy
Department of Pediatrics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
Pediatr Infect Dis J 23:877-9. 2004..She was successfully treated with surgical debridements and antifungal therapy with liposomal amphotericin B. A review of the literature indicates that zygomycosis caused by A. elegans is associated with traumatic inoculation...
Epidemiology, outcomes, and costs of invasive aspergillosis in immunocompromised children in the United States, 2000Theoklis E Zaoutis
Division of Infectious Diseases, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Pediatrics 117:e711-6. 2006..IA in adults has been well characterized; however, only a few small studies of IA in children have been reported. Therefore, the objective of this study was to describe the incidence and outcomes of children with IA...
Hospitalizations for endemic mycoses: a population-based national studyJaclyn H Chu
Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
Clin Infect Dis 42:822-5. 2006..6 and 28.7 cases per 1 million children and adults, respectively). Crude mortality rates were 5% and 7% among children and adults, respectively...
Outcomes attributable to neonatal candidiasisTheoklis E Zaoutis
Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Clin Infect Dis 44:1187-93. 2007..The incidence of candidiasis has increased in neonatal intensive care units, and invasive candidiasis is associated with significant morbidity and mortality. However, few data exist on outcomes directly attributable to neonatal candidiasis...
All catheter-related candidemia is not the same: assessment of the balance between the risks and benefits of removal of vascular cathetersThomas J Walsh
Clin Infect Dis 34:600-2. 2002
Comparative antifungal activities and plasma pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive pulmonary aspergillosis in persistently neutropenic rabbitsVidmantas Petraitis
Immunocompromised Host Section, Pediatric Oncology Branch, National Cancer Institute, Bethesda, Maryland 20892, USA
Antimicrob Agents Chemother 46:1857-69. 2002..albicans from persistently neutropenic rabbits with disseminated candidiasis but not of A. fumigatus from persistently neutropenic rabbits with invasive pulmonary aspergillosis...
The epidemiology and attributable outcomes of candidemia in adults and children hospitalized in the United States: a propensity analysisTheoklis E Zaoutis
Division of General Pediatrics, The Children s Hospital of Philadelphia, PA 19104, USA
Clin Infect Dis 41:1232-9. 2005....
Esophageal candidiasis in human immunodeficiency virus-infected pediatric patients after the introduction of highly active antiretroviral therapyChristine C Chiou
Immunocompromised Host Section, Pediatric Oncology Branch, National Cancer Institute, Bethesda, MD 20892, USA
Pediatr Infect Dis J 21:388-92. 2002....
Combination therapy in treatment of experimental pulmonary aspergillosis: synergistic interaction between an antifungal triazole and an echinocandinVidmantas Petraitis
Immunocompromised Host Section, Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
J Infect Dis 187:1834-43. 2003..The combination of an antifungal triazole and echinocandin may represent a new strategy for treatment of invasive pulmonary aspergillosis...
Clinical pharmacology of antifungal agents in pediatric patientsChristine C Chiou
National Cancer Institute, Immunocompromised Host Section, Pediatric Oncology Branch, National Institutes of Health, Bethesda, MD, USA
Expert Opin Pharmacother 8:2465-89. 2007..This article summarizes the clinical pharmacology of established and newly developed antifungal agents, including new triazoles and echinocandins in pediatric age groups...
Zygomycosis in a tertiary-care cancer center in the era of Aspergillus-active antifungal therapy: a case-control observational study of 27 recent casesDimitrios P Kontoyiannis
Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Infect Dis 191:1350-60. 2005..Anecdotal evidence suggests a rise in zygomycosis in association with voriconazole (VRC) use in immunosuppressed patients...
Study of common functional genetic polymorphisms of FCGR2A, 3A and 3B genes and the risk for cryptococcosis in HIV-uninfected patientsJoseph Meletiadis
National Cancer Institute, Bethesda, MD, USA
Med Mycol 45:513-8. 2007..40% in controls). An analysis of haplotypes showed a significant difference in distribution between cases and controls overall and in Caucasians...
Emergence of disseminated candidiasis caused by Candida krusei during treatment with caspofungin: case report and review of literatureRené Pelletier
Service de microbiologie et infectiologie, L Hôtel Dieu de Québec, Centre Hospitalier Universitaire de Quebec, Canada
Med Mycol 43:559-64. 2005..Caspofungin failure should be suspected in patients with persistent or emergent signs and symptoms of deep-seated invasive candidiasis...
