Robert B Wallace

..abstract:..

..We compared cognitive performance of older adults in the US and England, and sought to identify sociodemographic and medical factors associated with differences in cognitive function between the two countries...

..Stroke costs about $66B annually in the US, and also results in serious, long-term disability. Therefore, it is prudent to identify all possible risk factors and their effects so that appropriate intervention points may be targeted...

..We describe early dissemination patterns for first-line bevacizumab given for metastatic colorectal cancer treatment...

..Genome-wide association studies and subsequent replication studies have shown that single nucleotide polymorphisms (SNPs) in the chromosomal region 8q24 are associated with colorectal cancer susceptibility...

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..This study evaluated whether this risk is modified by participant characteristics...

..Sex, age, dementia, and frailty were significantly associated with mortality. This is one of the few studies to prospectively capture these declines in functional status after hip fracture...

..We investigated whether prior hospitalization was a risk factor for heart attacks among older adults in the survey on Assets and Health Dynamics among the Oldest Old...

..In this research, we classified older adults into population groups that persistently present with severe, non-severe, or indeterminate patterns of ED episodes. We then contrasted the three groups using a comprehensive set of covariates...

..Therefore, the authors studied the extent of long-term functional decline in older Medicare beneficiaries who were followed for varying time lengths, and the authors also identified the risk factors associated with those declines...

..The primary goal of this study was to determine the effect of the onset of major medical comorbidity and functional decline on subsequent weight change and increased depressive symptoms...

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..The purpose of this report is to characterize reports to poison control centers (PCCs) involving two widely used herbal dietary supplements (HDSs), Echinacea, and St. John's wort (SJW)...

..abstract:..

..We examined whether older adults who had continuity of care with a primary care physician (PCP) had lower mortality...

..To examine the extent to which US adults use herbs (herbal supplements) in accordance with evidence-based indications...

..Restless legs syndrome (RLS) is a common condition associated with decreased quality of life in older adults. This study estimates the prevalence, risk factors, and functional correlates of among U.S. elders...

..Cross-sectional studies suggest that parents eat more saturated fat than nonparents. Few studies exist on other dietary factors or using longitudinal data...

..The goal of this study was to characterize the rates and patterns of herb use among the API population of the United States...

..We identified 4-year (2 years before and 2 years after the index [baseline] interview) ED use patterns in older adults and the factors associated with them...

..Finally, we present data demonstrating that poor decision makers are more likely to fall prey to deceptive advertising, suggesting compromise of real-world judgment and decision-making abilities...

..To determine the association between inappropriate medication use and self-reported adverse drug effects (ADEs)...

..This article presents an interpersonal continuity of care measure...

..Health services use typically is examined using either self-reports or administrative data, but the concordance between the 2 is not well established...

..Discussion. Based on our findings, it is apparent that researchers need to examine the pathways between changes in weight and increases in depressive symptoms in the context of functional limitations and medical comorbidity...

..To examine the rates and correlates of depressive symptoms and syndromal depression in people with self-reported heart failure participating in a community study of people aged 70 and older...

..Identify the point-in-time relationship between Parkinson's disease (PD) signs and symptoms and measures of health-related quality of life (HRQL)...

..44-0.70). College graduates (OR 1.53; 95% CI = 1.22-1.91), older workers, full time workers (OR 3.99; 95% CI = 2.63-3.87), and the self-employed (OR 1.76; 95% CI = 1.28-2.41) were more likely than others to receive accommodations...

..Lastly, persons with self-reported alcohol abuse (OR, 1.30) were more likely to work, and persons with self-reported drug abuse (OR, 0.93) were not less likely to work, than others in our study population of Americans with disabilities...

..Failure to follow up on abnormal test results is common. A model was developed to capture the reasons why providers did not take action on abnormal test results...

..This study was designed to identify such correlates in a large sample of older adults, thus generating new data relevant to consumer education, medical training, and health practice and policy...

..Future clinical trials should test whether interventions to decrease inflammatory marker levels reduces hip fractures...

..There are several potential explanations for this finding with some evidence that at least part of the effect may be due to differential diagnosis between races...

..Clinical interviewing and population surveys both address this issue in complementary ways, and provide a further understanding of dietary supplement use patterns...

..To describe chemotherapy use and adverse events (AEs) for advanced-stage, non-small-cell lung cancer (NSCLC) in community practice, including descriptions according to variation by age...

..We examined whether hormone therapy affected physical function in women 65 to 79 years of age at enrollment...

..We identified hip fracture risks in a prospective national study...

..The purpose of this study was to determine whether retirement was associated with either weight gain or weight loss...

..To determine the effectiveness of treatment with conjugated equine estrogens (CEE) or with CEE combined with progestin (CEE + P) on age-related macular degeneration (AMD)...

..Observational studies and polyp recurrence trials are not conclusive regarding the effects of a low-fat dietary pattern on risk of colorectal cancer, necessitating a primary prevention trial...

..CONCLUSION: These data suggest that hormone therapy may influence joint health, but this observed decrease in risk may be limited to unopposed estrogen and may possibly be more important in hip than in knee osteoarthritis...

..The morbidity and cost associated with these outcomes may need to be considered in decisions regarding the use of estrogen therapy...

..We also illustrate potential uses of the ADAMS data and provide information to interested researchers on obtaining ADAMS and HRS data...

..Evaluation approaches to functional outcomes have rarely focused on the presence of specific comorbidities, particularly those involving mental health disorders...

..The keystone to this effort is the baseline patient survey administered approximately 4 months after diagnosis...

..Bisphenol A (BPA) is widely used in epoxy resins lining food and beverage containers. Evidence of effects in animals has generated concern over low-level chronic exposures in humans...

..We examined whether anemia in older persons increases the risk of subsequent decline in physical function, as measured by objective performance-based tests...

..to assess whether incident mobility disability and neighbourhood deprivation in older people are associated independent of the effects of individual socio-economic status, health behaviours and health status...

..To estimate disability plus mortality risks in older people according to level of alcohol intake...

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..The elderly population, including many who are long-term cancer survivors, is increasing. Aspects of quality of life in elderly cancer survivors are not well understood...

..CONCLUSION: Diets rich in lutein plus zeaxanthin may protect against intermediate AMD in healthy women younger than 75 years...

..Transitions such as retirement may represent points at which changes in health behaviour occur...

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..The role of common variation in the IL-18 gene on serum concentrations and functioning in old age is unknown...

..However, use or nonuse of HRT had less importance as a predictor of cardiovascular risk than did baseline levels of either CRP or IL-6...

..The optimal duration of treatment of women with postmenopausal osteoporosis is uncertain...

..The mechanism involved may be via greater cellular restorative activity and reduced stem cell senescence...

..We determined risks of short-term (2-year) hip fracture in a nationally representative, prospective cohort of community-dwelling elderly people 70 years or older...

..Cognitive impairment without dementia is associated with increased risk for disability, increased health care costs, and progression to dementia. There are no population-based prevalence estimates of this condition in the United States...

..To determine whether benzodiazepine use in older women increased the risk of decline in physical function...

..After adjustment for covariates, there were no significant associations between spousal caregiving and likelihood of caregiver receipt of preventive services...

..To examine the association of cardiovascular disease (CVD), CVD risk factors, and CVD treatment with age-related macular degeneration (AMD)...

..We determined the prognostic value of self-reported and performance-based measurement of function, including functional transitions and combining different measurement approaches, on utilization...

..To evaluate associations between nuclear cataract (determined from slitlamp photographs between May 2001 and January 2004) and lutein and zeaxanthin in the diet and serum in patients between 1994 and 1998 and macula between 2001 and 2004...

..We report the patterns of initial therapy focusing on the investigation of differences in receipt of recommended therapies according to multiple clinical and nonclinical patient characteristics...

..The efficacy of calcium with vitamin D supplementation for preventing hip and other fractures in healthy postmenopausal women remains equivocal...

..However, what additional prognostic information is gained by combining these approaches remains unknown...

..The hypothesis that a low-fat dietary pattern can reduce breast cancer risk has existed for decades but has never been tested in a controlled intervention trial...

..To assess the relationship between cognitive function, socioeconomic status, and neighborhood deprivation (lack of local resources of all types, financial and otherwise)...

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..We hypothesize there will be little or no treatment survival benefits for patients on the ENSCLC patients provides the rationale for this study. ..

..Remaining activities include program administration, including ongoing planning and evaluation activities, and provision of variously sized pilot grants to promote research in the areas selected for development. ..

..We hypothesize there will be little or no treatment survival benefits for patients on the ENSCLC patients provides the rationale for this study. ..