Research Topics
Species | TAMARA WALLSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Parental history of alcoholism and problem behaviors in Native-American children and adolescentsT L Wall
Department of Neuropharmacology, The Scripps Research Institute, University of California, San Diego, La Jolla, USA
Alcohol Clin Exp Res 24:30-4. 2000..Native-American Indians, in addition to high rates of alcoholism and alcohol-related mortality, have the highest prevalence of a positive family history for alcoholism of all ethnic groups in the United States...
Genetic associations of alcohol dehydrogenase with alcohol use disorders and endophenotypes in white college studentsTamara L Wall
Department of Psychiatry, University of California, San Diego, San Diego, CA 92161, USA
J Abnorm Psychol 114:456-65. 2005..These findings are consistent with the hypothesis that enhanced sensitivity to alcohol and lower levels of alcohol use reflect the mechanism by which ADH1B*2 protects against developing an AUD...
Protective association of genetic variation in alcohol dehydrogenase with alcohol dependence in Native American Mission IndiansTamara L Wall
Department of Neuropharmacology, Scripps Research Institute, San Diego, CA, USA
Am J Psychiatry 160:41-6. 2003..An additional goal was to determine if any associations exist between these polymorphisms and the endophenotype, maximum number of drinks ever consumed in a 24-hour period...
Genetic associations of alcohol and aldehyde dehydrogenase with alcohol dependence and their mechanisms of actionTamara L Wall
Department of Psychiatry, University of California and the Psychology Service, Veterans Affairs San Diego Healthcare System 92161, USA
Ther Drug Monit 27:700-3. 2005..These findings highlight the value of trying to elucidate the mechanism by which genes ultimately give rise to differences in alcohol dependence through the examination of mediating behaviors...
A genetic association with the development of alcohol and other substance use behavior in Asian AmericansT L Wall
Department of Psychiatry, University of California, San Diego, and Psychology Service, Veterans Affairs San Diego Healthcare System, USA
J Abnorm Psychol 110:173-8. 2001..These findings suggest that ALDH2 is associated with the development of not only alcohol-related behavior but other substance use behavior as well...
Ethnic differences in level of response to alcohol between Chinese Americans and Korean AmericansNicole C E Duranceaux
Department of Psychiatry, University of California, San Diego, CA, USA
J Stud Alcohol Drugs 69:227-34. 2008..The current study examined self-report level of response to alcohol, ALDH2 and ADH1B, country of origin, and family history of alcoholism in 154 Chinese- and 181 Korean-American college students...
ALDH2*2 is associated with a decreased likelihood of alcohol-induced blackouts in Asian American college studentsSusan E Luczak
Department of Psychiatry, University of California, San Diego, USA
J Stud Alcohol 67:349-53. 2006....
Associations of variations in alcohol dehydrogenase genes with the level of response to alcohol in non-AsiansNicole C E Duranceaux
Department of Psychiatry, University of California, San Diego, California 92161, USA
Alcohol Clin Exp Res 30:1470-8. 2006..Variations in the ADH1B and ADH1C genes may influence the LR to alcohol by increasing levels of acetaldehyde during alcohol metabolism, although most data on this question come from Asian populations...
Religious influences on heavy episodic drinking in Chinese-American and Korean-American college studentsSusan E Luczak
Department of Psychiatry, University of California, San Diego, California, USA
J Stud Alcohol 64:467-71. 2003..Moreover, service attendance appears to more strongly influence heavy drinking in individuals who are not already protected by an ALDH2*2 allele...
Association of ALDH1 promoter polymorphisms with alcohol-related phenotypes in southwest California IndiansCindy L Ehlers
Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California 92037, USA
Alcohol Clin Exp Res 28:1481-6. 2004..The aim of this study was to determine the prevalence of these polymorphisms in a sample of Southwest California Indians and to test for associations with alcohol dependence and other substance-related behaviors...
Stability of heavy episodic drinking in Chinese- and Korean-American college students: effects of ALDH2 gene status and behavioral undercontrolNeal Doran
Department of Psychiatry, University of California, San Diego, La Jolla, California, USA
J Stud Alcohol Drugs 68:789-97. 2007..The purpose of this longitudinal study was to examine the roles of ALDH2 and behavioral undercontrol (a temperamental trait that is associated with conduct disorder) in stability of heavy episodic drinking...
Associations of ALDH2 and ADH1B genotypes with response to alcohol in Asian AmericansTravis A R Cook
Department of Psychiatry, University of California, San Diego, USA
J Stud Alcohol 66:196-204. 2005..This study was designed to determine whether the ADH1B genotype is associated with more intense reactions to alcohol after controlling for the ALDH2 genotype...
Genomic screen for loci associated with alcohol dependence in Mission IndiansCindy L Ehlers
Department of Neuropharmacology, The Scripps Research Institute, University of California, San Diego, California 92037, USA
Am J Med Genet B Neuropsychiatr Genet 129:110-5. 2004....
ALDH2 status and conduct disorder mediate the relationship between ethnicity and alcohol dependence in Chinese, Korean, and White American college studentsSusan E Luczak
University of California, San Diego and Veterans Medical Research Foundation, 92161, USA
J Abnorm Psychol 113:271-8. 2004..Results suggest that different rates of risk (e.g., conduct disorder) and protective (e.g., ALDH2 status) factors partially account for ethnic differences in rates of alcohol dependence...
Meta-analyses of ALDH2 and ADH1B with alcohol dependence in AsiansSusan E Luczak
Department of Psychology, University of Southern California, Los Angeles 90089 1061, and the Veterans Medical Research Foundation, San Diego, CA, USA
Psychol Bull 132:607-21. 2006..These findings highlight the importance of methodological issues and potential gene-gene and gene-environment interactions that must be considered when examining relationships between genetic polymorphisms and phenotypes...
Genetic risk for alcoholism relates to level of response to alcohol in Asian-American men and womenSusan E Luczak
Department of Psychiatry, University of California, San Diego 92161 2002, USA
J Stud Alcohol 63:74-82. 2002..The present study was designed to determine whether similar levels of response to alcohol, using objective and subjective measurements, are seen in men and women with different ALDH2 genotypes...
ALDH2, ADH1B, and ADH1C genotypes in Asians: a literature reviewMimy Y Eng
Department of Psychiatry, University of California, San Diego, USA
Alcohol Res Health 30:22-7. 2007..ADH1B*2 is highly prevalent among Asians, with the exception of Indians. ADH1C*1 also is highly prevalent in Asians, but has only been examined in a few studies of Chinese and Korean samples...
Psychosocial, cultural and genetic influences on alcohol use in Asian American youthChristian S Hendershot
Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA
J Stud Alcohol 66:185-95. 2005..The present study assessed parental alcohol use, acculturation and ALDH2 gene status in relation to lifetime, current and heavy episodic drinking among Chinese and Korean American undergraduates...
A prospective study of cigarette smoking initiation during college: Chinese and Korean American studentsMark G Myers
Psychology Service, VA San Diego Healthcare System, San Diego, CA 92161, USA
Health Psychol 28:448-56. 2009..The present study was a prospective investigation of baseline influences on initial smoking and transition to established smoking among college students who had not smoked prior to college...
Prevalence, predictors, and outcomes of early adherence after starting or changing antiretroviral therapyW Christopher Mathews
Department of Medicine, University of California, San Diego, California 92103, USA
AIDS Patient Care STDS 16:157-72. 2002..Structured assessment of self-reported adherence is an inexpensive and useful tool to assist clinicians in monitoring adherence...
Binge drinking in Jewish and non-Jewish white college studentsSusan E Luczak
University of California, San Diego, School of Medicine, USA
Alcohol Clin Exp Res 26:1773-8. 2002..More research is needed to identify additional factors, including other religious, cultural, genetic, and biological influences, that protect Jewish Americans from heavy drinking...
The clinical course of alcoholism in 243 Mission IndiansCindy L Ehlers
Department of Neuropharmacology, Scripps Research Institute, VCN 14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
Am J Psychiatry 161:1204-10. 2004..This study was conducted to describe the order of appearance and the progression of alcohol-related life events in Mission Indian men and women with a lifetime diagnosis of alcohol dependence...
Heritability of illicit drug use and transition to dependence in Southwest California IndiansCindy L Ehlers
Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037, USA
Psychiatr Genet 17:171-6. 2007....
Differences in pharmacogenetics of nicotine and alcohol metabolism: review and recommendations for future researchTamara L Wall
Department of Psychiatry, University of California, San Diego, Psychology Service, Veterans Affairs San Diego Healthcare System, San Diego, California, USA
Nicotine Tob Res 9:S459-74. 2007....
Family history of alcohol dependence in Asian AmericansNicole C Ebberhart
San Diego State University, Joint Doctoral Program in Clinical Psychology, San Diego, California, USA
J Psychoactive Drugs 35:375-7. 2003..These findings highlight the heterogeneity in vulnerability to alcohol-related problems between Asian subgroups...
Psychiatric diagnoses among Mission Indian children with and without a parental history of alcohol dependenceDavid A Gilder
Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California 92037, USA
J Stud Alcohol 63:18-23. 2002..CONCLUSIONS: Parental alcohol dependence does not appear to relate to increased psychopathology among Mission Indian children, but living in a single parent household may be associated with increased rates of some psychiatric disorders...
Comorbidity of select anxiety and affective disorders with alcohol dependence in southwest California IndiansDavid A Gilder
Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037, USA
Alcohol Clin Exp Res 28:1805-13. 2004....
EEG alpha and level of response to alcohol in Hispanic- and non-Hispanic-American young adults with a family history of alcoholismCindy L Ehlers
Department of Neuropharmacology, Scripps Research Institute, Department of Psychiaty, University of California, San Diego, USA
J Stud Alcohol 65:301-8. 2004..The present study's aims were to investigate EEG alpha and response to alcohol in Hispanic-American and non-Hispanic-American young adults...
Ethnic variation in CYP2A6*7, CYP2A6*8 and CYP2A6*10 as assessed with a novel haplotyping methodJill C Mwenifumbo
University of Toronto, Toronto, Canada
Pharmacogenet Genomics 15:189-92. 2005..Our new method demonstrated higher frequencies of CYP2A6*7 and CYP2A6*10, and a lower frequency of CYP2A6*8 in Asian populations, but no significant change of allele frequencies in Caucasian or African-Canadian populations...
Evaluation of aldehyde dehydrogenase 1 promoter polymorphisms identified in human populationsJohn P Spence
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
Alcohol Clin Exp Res 27:1389-94. 2003....
Biological and behavioral markers of alcohol sensitivityKim Fromme
Department of Psychology, The University of Texas at Austin, Austin, Texas 78712, USA
Alcohol Clin Exp Res 28:247-56. 2004..Dr. David Goldman provides concluding remarks...
Testing of an orthogonal measure of cultural identification with adult mission IndiansKamilla L Venner
Center on Alcoholism, Substance Abuse and Addictions, Department of Psychology, University of New Mexico, Albuquerque 87131 1161, USA
Cultur Divers Ethnic Minor Psychol 12:632-43. 2006..Confirmatory factor analysis revealed 2 factors: (1) Anglo American Identification and (2) Native American Identification. These results indicate the OCIS is a reliable and valid instrument for use with adult Native Americans...
Research Grants
- Alcohol Research: Risk and Protection in Ethnic GroupsTAMARA WALL; Fiscal Year: 2007..Wall's Independent Scientist Award will provide her the opportunity to continue to engage in research activities on nearly a full-time basis, thus ensuring her continued development as a scientist and as a mentor. ..
- Alcohol Involvement in Asian American Men and WomenTAMARA WALL; Fiscal Year: 2005....
- Alcohol Involvement in Asian American Men and WomenTamara L Wall; Fiscal Year: 2010..Through this understanding, findings from the proposed research have the potential to lead to more effective prevention of alcoholism. ..
