Research Topics
| Jeffrey WallSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Archaic admixture in the human genomeJeffrey D Wall
Program in Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089, USA
Curr Opin Genet Dev 16:606-10. 2006..Extensive sequencing of Neanderthal and other archaic human nuclear DNA has the potential to answer this question definitively within the next few years...
Incomplete lineage sorting is common in extant gibbon generaJeffrey D Wall
Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 8:e53682. 2013..This uncertainty is due to short internal branch lengths and extensive incomplete lineage sorting across taxa. The true phylogenetic relationships among gibbon genera will likely require a more extensive whole-genome sequence analysis...
Paleopopulation geneticsJeffrey D Wall
Institute for Human Genetics and Department of Epidemiology and Biostatistics, University of California, San Francisco, California 94134, USA
Annu Rev Genet 46:635-49. 2012..In this review, we discuss recent developments in this emerging field as well as prospects for the future...- Genomics through the lens of next-generation sequencingJohn A Capra
Gladstone Institute of Cardiovascular Disease, University of California San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA
Genome Biol 11:306. 2010..A report on the 23rd annual meeting on 'The Biology of Genomes', 11-15 May 2010, Cold Spring Harbor, USA... - Intergenic DNA sequences from the human X chromosome reveal high rates of global gene flowMurray P Cox
ARL Division of Biotechnology, University of Arizona, AZ 85721, USA
BMC Genet 9:76. 2008..This is partly because most analyses have applied one of two simple models of population structure, the island model or the splitting model, which make unrealistic biological assumptions... - Genetic variation in Native Americans, inferred from Latino SNP and resequencing dataJeffrey D Wall
Institute for Human Genetics and Department of Epidemiology and Biostatistics, University of California San Francisco, CA, USA
Mol Biol Evol 28:2231-7. 2011..5 Kya; when uncertainty in the estimation process is taken into account, our results are consistent with archeological estimates for the colonization of the Americas... - Detecting ancient admixture and estimating demographic parameters in multiple human populationsJeffrey D Wall
Department of Epidemiology and Biostatistics, Institute for Human Genetics, University of California San Francisco, CA, USA
Mol Biol Evol 26:1823-7. 2009..We find evidence for this ancient admixture in European, East Asian, and West African samples, suggesting that admixture between diverged hominin groups may be a general feature of recent human evolution... - Inconsistencies in Neanderthal genomic DNA sequencesJeffrey D Wall
Institute for Human Genetics, University of California San Francisco, San Francisco, California, USA
PLoS Genet 3:1862-6. 2007.... - Possible ancestral structure in human populationsVincent Plagnol
Department of Molecular and Computational Biology, University of Southern California, Los Angeles, California, USA
PLoS Genet 2:e105. 2006..While Neanderthals form an obvious archaic source population candidate in Europe, there is not yet a clear source population candidate in West Africa... - Haplotypic background of a private allele at high frequency in the AmericasKari B Schroeder
Department of Anthropology, University of California, Davis, CA, USA
Mol Biol Evol 26:995-1016. 2009.... - A novel DNA sequence database for analyzing human demographic historyJeffrey D Wall
Institute for Human Genetics and Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94143, USA
Genome Res 18:1354-61. 2008.... - The pattern of polymorphism in Arabidopsis thalianaMagnus Nordborg
Molecular and Computational Biology, University of Southern California, Los Angeles, California, USA
PLoS Biol 3:e196. 2005..Despite this, our data support the utility of A. thaliana as a model for evolutionary functional genomics... - Sex-biased evolutionary forces shape genomic patterns of human diversityMichael F Hammer
ARL Division of Biotechnology, University of Arizona, Tucson, Arizona, USA
PLoS Genet 4:e1000202. 2008.... - Estimating recombination rates from single-nucleotide polymorphisms using summary statisticsBadri Padhukasahasram
Molecular and Computational Biology and Biostatistics Division, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
Genetics 174:1517-28. 2006..We used our method to analyze a human data set recently genotyped by Perlegen Sciences... - Estimating recombination rates using three-site likelihoodsJeffrey D Wall
Program in Molecular and Computational Biology, University of Southern California, Los Angeles, California 90089, USA
Genetics 167:1461-73. 2004..While existing methods can easily estimate an "average" gene conversion rate over many loci, they cannot reliably estimate gene conversion rates for a single region of the genome... - Close look at gene conversion hot spotsJeffrey D Wall
Nat Genet 36:114-5. 2004 - Comparative linkage-disequilibrium analysis of the beta-globin hotspot in primatesJeffrey D Wall
Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA
Am J Hum Genet 73:1330-40. 2003..These results suggest a time scale for the evolution of hotspots in primates. Furthermore, they allow us to propose diverged sequence elements that may contribute to the differences in the recombinational landscape in the two species...
Research Grants
- Simulation algorithms for genome-wide data and application to admixed dataJeffrey Wall; Fiscal Year: 2009..This work will also help us determine the marker density and sample size needed for future association studies. ..
- Simulation algorithms for genome-wide data and application to admixed dataJeffrey Wall; Fiscal Year: 2007..This work will also help us determine the marker density and sample size needed for future association studies. ..