K Waites

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Antimicrobial resistance among isolates of respiratory tract infection pathogens from the southern United States: data from the PROTEKT US surveillance program 2000/2001
    Ken Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35233 7331, USA
    South Med J 96:974-85. 2003
  2. pmc Relative fitness of fluoroquinolone-resistant Streptococcus pneumoniae
    Crystal N Johnson
    University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Emerg Infect Dis 11:814-20. 2005
  3. pmc Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Antimicrob Agents Chemother 52:3776-8. 2008
  4. pmc Comparative in vitro susceptibilities and bactericidal activities of investigational fluoroquinolone ABT-492 and other antimicrobial agents against human mycoplasmas and ureaplasmas
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Antimicrob Agents Chemother 47:3973-5. 2003
  5. pmc Dissemination of macrolide-resistant Streptococcus pneumoniae isolates containing both erm(B) and mef(A) in South Korea
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    J Clin Microbiol 41:5787-91. 2003
  6. ncbi request reprint Effect of cranberry extract on bacteriuria and pyuria in persons with neurogenic bladder secondary to spinal cord injury
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 7331, USA
    J Spinal Cord Med 27:35-40. 2004
  7. pmc Mycoplasma pneumoniae and its role as a human pathogen
    Ken B Waites
    Department of Pathology, WP 230, University of Alabama at Birmingham, 619 19th St South, Birmingham, AL 35249, USA
    Clin Microbiol Rev 17:697-728, table of contents. 2004
  8. ncbi request reprint Microbiology of the urethra and perineum and its relationship to bacteriuria in community-residing men with spinal cord injury
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    J Spinal Cord Med 27:448-52. 2004
  9. pmc Comparative in vitro activities of investigational peptide deformylase inhibitor NVP LBM-415 and other agents against human mycoplasmas and ureaplasmas
    Ken B Waites
    Department of Pathology, WP 230, 619 19th Street South, Birmingham, AL 35249, USA
    Antimicrob Agents Chemother 49:2541-2. 2005
  10. pmc Mycoplasmas and ureaplasmas as neonatal pathogens
    Ken B Waites
    Department of Pathology, University of Alabama, Birmingham, Alabama 35249, USA
    Clin Microbiol Rev 18:757-89. 2005

Collaborators

Detail Information

Publications50

  1. ncbi request reprint Antimicrobial resistance among isolates of respiratory tract infection pathogens from the southern United States: data from the PROTEKT US surveillance program 2000/2001
    Ken Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35233 7331, USA
    South Med J 96:974-85. 2003
    ....
  2. pmc Relative fitness of fluoroquinolone-resistant Streptococcus pneumoniae
    Crystal N Johnson
    University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Emerg Infect Dis 11:814-20. 2005
    ..However, the strain was equally able to cause competitive or noncompetitive lung infections as well as EF3030...
  3. pmc Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Antimicrob Agents Chemother 52:3776-8. 2008
    ..9% of the inoculum at 24 h for 2 isolates. The excellent in vitro activity of DC-159a demonstrates its potential for use in the treatment of infections due to mycoplasmas and ureaplasmas...
  4. pmc Comparative in vitro susceptibilities and bactericidal activities of investigational fluoroquinolone ABT-492 and other antimicrobial agents against human mycoplasmas and ureaplasmas
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Antimicrob Agents Chemother 47:3973-5. 2003
    ..ABT-492 MICs were < or =1 microg/ml, and the agent was bactericidal against selected isolates of M. pneumoniae and M. hominis. ABT-492 has potential for treatment of infections due to these microorganisms...
  5. pmc Dissemination of macrolide-resistant Streptococcus pneumoniae isolates containing both erm(B) and mef(A) in South Korea
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    J Clin Microbiol 41:5787-91. 2003
    ..1%) contained mef(A) and erm(B). Nineteen isolates containing mef(A) and erm(B) belonged to serotype 19F, and seven isolates were identical to the Taiwan(19F)-14 clone...
  6. ncbi request reprint Effect of cranberry extract on bacteriuria and pyuria in persons with neurogenic bladder secondary to spinal cord injury
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 7331, USA
    J Spinal Cord Med 27:35-40. 2004
    ..To determine whether antibacterial effects of cranberry extract will reduce or eliminate bacteriuria and pyuria in persons with spinal cord injury (SCI)...
  7. pmc Mycoplasma pneumoniae and its role as a human pathogen
    Ken B Waites
    Department of Pathology, WP 230, University of Alabama at Birmingham, 619 19th St South, Birmingham, AL 35249, USA
    Clin Microbiol Rev 17:697-728, table of contents. 2004
    ..As more is learned about the pathogenesis and immune response elicited by M. pneumoniae, improvement in methods for diagnosis and prevention of disease due to this organism may occur...
  8. ncbi request reprint Microbiology of the urethra and perineum and its relationship to bacteriuria in community-residing men with spinal cord injury
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    J Spinal Cord Med 27:448-52. 2004
    ..We performed a prospective study of bacterial flora of the urethra and perineum in men with and without bacteriuria to understand more completely the relationship between bacterial colonization and invasion of the urinary tract...
  9. pmc Comparative in vitro activities of investigational peptide deformylase inhibitor NVP LBM-415 and other agents against human mycoplasmas and ureaplasmas
    Ken B Waites
    Department of Pathology, WP 230, 619 19th Street South, Birmingham, AL 35249, USA
    Antimicrob Agents Chemother 49:2541-2. 2005
    ..LBM-415 was active against M. pneumoniae (MICs, <or=0.008 microg/ml). It showed no activity against M. hominis and M. fermentans and modest activity against Ureaplasma spp...
  10. pmc Mycoplasmas and ureaplasmas as neonatal pathogens
    Ken B Waites
    Department of Pathology, University of Alabama, Birmingham, Alabama 35249, USA
    Clin Microbiol Rev 18:757-89. 2005
    ....
  11. pmc Evaluation of 3 methods of bladder irrigation to treat bacteriuria in persons with neurogenic bladder
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Spinal Cord Med 29:217-26. 2006
    ....
  12. pmc Antimicrobial susceptibility among pathogens collected from hospitalized patients in the United States and in vitro activity of tigecycline, a new glycylcycline antimicrobial
    Ken B Waites
    Section of Clinical Microbiology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Antimicrob Agents Chemother 50:3479-84. 2006
    ....
  13. pmc Revaccination of adults with spinal cord injury using the 23-valent pneumococcal polysaccharide vaccine
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    J Spinal Cord Med 31:53-9. 2008
    ..This study was undertaken to determine the effect of revaccination with the pneumococcal vaccine on the immune response and the frequency of adverse reactions in this population...
  14. ncbi request reprint New concepts of Mycoplasma pneumoniae infections in children
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, P230 West Pavilion, Birmingham, AL 35233, USA
    Pediatr Pulmonol 36:267-78. 2003
  15. pmc In vitro susceptibilities of Mycoplasma hominis to six fluoroquinolones as determined by E test
    K B Waites
    Departments of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Antimicrob Agents Chemother 43:2571-3. 1999
    ..25; and ciprofloxacin, 0.5. Increasing the amount of inoculum or incubation in CO(2) elevated MICs by </=1 dilution. E tests produce fluoroquinolone MICs comparable to those obtained by agar and microbroth dilution for M. hominis...
  16. pmc Direct susceptibility testing with positive BacT/Alert blood cultures by using MicroScan overnight and rapid panels
    K B Waites
    Department of Pathology, University of Alabama at Birmingham, 35233, USA
    J Clin Microbiol 36:2052-6. 1998
    ..When discrepant results occur with direct-susceptibility testing, they are more likely to show false susceptibility than false resistance...
  17. ncbi request reprint Comparative in vitro activities of four new fluoroquinolones against Streptococcus pneumoniae determined by Etest
    K Waites
    Department of Pathology, University of Alabama at Birmingham 35233 7331, USA
    Int J Antimicrob Agents 9:215-8. 1998
    ..Two isolates, both serotype 6, with high-level quinolone resistance (> or = 8 micrograms/ml) were detected. The Etest is a practical means for determining S. pneumoniae susceptibilities to new fluoroquinolones...
  18. pmc Use of clindamycin disks To detect macrolide resistance mediated by ermB and mefE in Streptococcus pneumoniae isolates from adults and children
    K Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Clin Microbiol 38:1731-4. 2000
    ..Macrolide resistance mediated by ermB is usually of greater magnitude than that due to mefE. Clinical studies are needed to determine the significance of high- versus low-level macrolide resistance in S. pneumoniae...
  19. ncbi request reprint Bacteremia after spinal cord injury in initial versus subsequent hospitalizations
    K B Waites
    Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham, USA
    J Spinal Cord Med 24:96-100. 2001
    ..The increase in drug-resistant bacteria in recent years underscores the importance of gathering accurate microbiological information...
  20. pmc Evaluation of BacT/ALERT system for detection of Mycoplasma hominis in simulated blood cultures
    K B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 7331, USA
    J Clin Microbiol 39:4328-31. 2001
    ..hominis and that specialized media and incubation conditions designed for optimum cultivation of mycoplasmas should be employed when this organism is suspected on clinical grounds...
  21. pmc Detection of Chlamydia trachomatis endocervical infections by ligase chain reaction versus ACCESS Chlamydia antigen assay
    K B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35233 7331, USA
    J Clin Microbiol 37:3072-3. 1999
    ..ACCESS had a sensitivity of 83.9%, a specificity of 99.7%, a positive predictive value of 96.3%, and a negative predictive value of 98.5%...
  22. ncbi request reprint Inhibitory and bactericidal activities of gemifloxacin and other antimicrobials against Mycoplasma pneumoniae
    Ken B Waites
    Department of Pathology, WP 230, University of Alabama at Birmingham, 619n 19th Street South, Birmingham, AL 35249, USA
    Int J Antimicrob Agents 21:574-7. 2003
    ..MBCs for gemifloxacin were predominantly within 2-4 times the corresponding MIC values, indicating a bactericidal effect...
  23. pmc In vitro activities of ABT-773 and other antimicrobials against human mycoplasmas
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Antimicrob Agents Chemother 47:39-42. 2003
    ..pneumoniae and 0.25 microg/ml for M. fermentans, but they were several dilutions higher for M. hominis and Ureaplasma spp. ABT-773 has great potential for further study for the treatment of infections due to mycoplasmas and ureaplasmas...
  24. ncbi request reprint Emerging macrolide resistance in Mycoplasma pneumoniae in children: detection and characterization of resistant isolates
    Xiao Li
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Pediatr Infect Dis J 28:693-6. 2009
    ..A rapid technique to identify macrolide-resistant M. pneumoniae is needed to guide management of patients with community-acquired respiratory infections...
  25. pmc Genetic relatedness of levofloxacin-nonsusceptible Streptococcus pneumoniae isolates from North America
    Crystal N Johnson
    Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    J Clin Microbiol 41:2458-64. 2003
    ..However, seven LNSP were found to be related to three international clones by PFGE...
  26. pmc In vitro susceptibilities to and bactericidal activities of garenoxacin (BMS-284756) and other antimicrobial agents against human mycoplasmas and ureaplasmas
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Antimicrob Agents Chemother 47:161-5. 2003
    ..hominis by measurement of minimal bactericidal activities and by time-kill studies. Further study of garenoxacin is required, as it has great potential for use in the treatment of infections due to mycoplasmas and ureaplasmas...
  27. pmc Characterization of ureaplasmas isolated from preterm infants with and without bronchopulmonary dysplasia
    Brenda Katz
    Department of Pathology, University of Alabama at Birmingham, 35249 7331, USA
    J Clin Microbiol 43:4852-4. 2005
    ..urealyticum. U. parvum was detected more often than U. urealyticum. There was no significant difference or trend in the prevalence of either species between infants with or without bronchopulmonary dysplasia when isolated alone...
  28. pmc USA300 genotype community-associated methicillin-resistant Staphylococcus aureus as a cause of surgical site infections
    Mukesh Patel
    Department of Medicine, University of Alabama at Birmingham, THT 229, 1530 3rd Avenue South, Birmingham, AL 35294 0006, USA
    J Clin Microbiol 45:3431-3. 2007
    ..CA-MRSA has become a prominent cause of SSI at our institution...
  29. doi request reprint Dissemination of community-associated methicillin-resistant Staphylococcus aureus in a tertiary care hospital
    Mukesh Patel
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, 35294 0006, USA
    South Med J 101:40-5. 2008
    ..The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) was investigated at a tertiary care hospital, and relationship was made between the clinical and genetic definitions of community- and healthcare-associated MRSA...
  30. doi request reprint Active surveillance to determine the impact of methicillin-resistant Staphylococcus aureus colonization on patients in intensive care units of a Veterans Affairs Medical Center
    Mukesh Patel
    Birmingham Veterans Affairs Medical Center, Birmingham, Alabama, USA
    Infect Control Hosp Epidemiol 29:503-9. 2008
    ..We sought to describe the impact of MRSA colonization on patients admitted to intensive care units (ICUs) in the Birmingham Veterans Affairs Medical Center (VAMC)...
  31. doi request reprint The use of a biodegradable, load-bearing scaffold as a carrier for antibiotics in an infected open fracture model
    Rena L Stewart
    Division of Orthopaedics, University of Alabama at Birmingham, Birmingham, AL 35233 3409, USA
    J Orthop Trauma 24:587-91. 2010
    ..This study investigates the use of such scaffolds with gentamicin (along with bone morphogenetic protein) in an infected rat open fracture model to decrease osteomyelitis and promote fracture healing...
  32. ncbi request reprint The role of Mycoplasma in upper respiratory infections
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, WP 230, 619 19th Street South, Birmingham, AL 35249, USA
    Curr Infect Dis Rep 11:198-206. 2009
    ..pneumoniae in upper respiratory tract infections; a brief discussion of its cell biology, pathogenic mechanisms, and epidemiology; and recommendations for laboratory diagnosis and management...
  33. doi request reprint Congenital and opportunistic infections: Ureaplasma species and Mycoplasma hominis
    Ken B Waites
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Semin Fetal Neonatal Med 14:190-9. 2009
    ....
  34. pmc Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101
    Ken B Waites
    Department of Pathology, 619 19th Street South, WP 230, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Antimicrob Agents Chemother 53:2139-41. 2009
    ..All isolates, including two macrolide-resistant M. pneumoniae isolates, were inhibited by CEM-101 at < or = 0.5 microg/ml, making CEM-101 the most potent compound tested...
  35. pmc New insights into the pathogenesis and detection of Mycoplasma pneumoniae infections
    Ken B Waites
    University of Alabama at Birmingham, WP 230, 619 19th Street South, Birmingham, AL 35249, USA
    Future Microbiol 3:635-48. 2008
    ....
  36. ncbi request reprint Ureaplasma infection and neonatal lung disease
    Robert L Schelonka
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA
    Semin Perinatol 31:2-9. 2007
    ....
  37. doi request reprint Fusobacterium necrophorum bacteremic tonsillitis: 2 Cases and a review of the literature
    Robert M Centor
    Department of Internal Medicine, University of Alabama at Birmingham, Huntsville, 35801, USA
    Anaerobe 16:626-8. 2010
    ..necrophorum. Recognition of such patients might prevent Lemierre syndrome...
  38. pmc Prevalence of inducible clindamycin resistance among community- and hospital-associated Staphylococcus aureus isolates
    Mukesh Patel
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, THT 229, 1530 3rd Avenue South, Birmingham, AL 35294 0006, USA
    J Clin Microbiol 44:2481-4. 2006
    ..Due to the low prevalence of MLSBi among CA-MRSA isolates, clindamycin remains a useful option for outpatient therapy...
  39. ncbi request reprint Critical appraisal of the role of Ureaplasma in the development of bronchopulmonary dysplasia with metaanalytic techniques
    Robert L Schelonka
    Department of Pediatrics University of Alabama at Birmingham, Birmingham, AL, USA
    Pediatr Infect Dis J 24:1033-9. 2005
    ....
  40. pmc Nosocomial spread of Enterococcus faecium resistant to vancomycin and linezolid in a tertiary care medical center
    Thomas E Dobbs
    Department of Medicine, University of Alabama at Birmingham, 619 South 19th St, 35249, USA
    J Clin Microbiol 44:3368-70. 2006
    ..Epidemiologic investigation and pulsed-field gel electrophoresis patterns indicated a clonal outbreak related to nosocomial spread...
  41. ncbi request reprint In vitro comparison of agar and microbroth dilution methods for determination of MICs for Mycoplasma hominis
    Nicholaus J Hilliard
    Department of Pathology, University of Alabama at Birmingham, WP 230, 619 19th St S Birmingham, AL 35249, USA
    J Microbiol Methods 60:285-8. 2005
    ..Both methods provide reproducible results. Agar dilution tends to yield higher MIC values for some drugs...
  42. pmc Detection and characterization of human Ureaplasma species and serovars by real-time PCR
    Li Xiao
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    J Clin Microbiol 48:2715-23. 2010
    ..These assays provide quick and reliable means for investigating the epidemiology and pathogenicity of ureaplasmas at the serovar level...
  43. pmc Rapid multiplex assay for serotyping pneumococci with monoclonal and polyclonal antibodies
    Jigui Yu
    Department of Pathology, University of Alabama at Birmingham, AL, USA
    J Clin Microbiol 43:156-62. 2005
    ..This system should be very useful in serotyping clinical isolates for evaluating pneumococcal vaccine efficacy...
  44. ncbi request reprint In vitro activity of ertapenem (MK-0826) against multi-drug resistant Streptococcus pneumoniae compared with 13 other antimicrobials
    Nicholaus J Hilliard
    Department of Pathology, University of Alabama at Birmingham, WP P230N, 619 19th Street South, 35249 7331, USA
    Int J Antimicrob Agents 20:136-40. 2002
    ..pneumoniae, including infections caused by organisms with reduced susceptibilities to other antimicrobial agents...
  45. ncbi request reprint Epidemiology, clinical manifestations, pathogenesis and laboratory detection of Mycoplasma pneumoniae infections
    THOMAS PRESCOTT ATKINSON
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA
    FEMS Microbiol Rev 32:956-73. 2008
    ....
  46. pmc Bacillus cereus bacteremia in a preterm neonate
    Nicholaus J Hilliard
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    J Clin Microbiol 41:3441-4. 2003
    ....
  47. ncbi request reprint Nosocomial ventriculitis due to Roseomonas gilardii complicating subarachnoid haemorrhage
    Jason S Nolan
    Department of Pathology, University of Alabama at Birmingham, WP 230, 619 19th Street South, Birmingham, AL 35249, USA
    J Infect 50:244-51. 2005
    ....
  48. ncbi request reprint Effective communication of antimicrobial susceptibility data by pathologists to clinicians
    Ken B Waites
    Department of Pathology, University of Alabama, Birmingham, AL, USA
    Adv Exp Med Biol 563:165-77. 2005
    ....
  49. pmc Prevalence of plasmid-mediated quinolone resistance
    George A Jacoby
    Infectious Disease Department, Lahey Clinic, Burlington, Massachusetts, USA
    Antimicrob Agents Chemother 47:559-62. 2003
    ..This plasmid and one carrying the complete microcin B17 operon slightly decreased sparfloxacin susceptibility but had a much less protective effect than pMG252. Plasmid-mediated quinolone resistance was thus rare in the sample examined...
  50. ncbi request reprint Bactericidal activity of levofloxacin against Mycoplasma pneumoniae
    Lynn B Duffy
    J Antimicrob Chemother 52:527-8. 2003