Research Topics
| K WaitesSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmasKen B Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
Antimicrob Agents Chemother 52:3776-8. 2008..9% of the inoculum at 24 h for 2 isolates. The excellent in vitro activity of DC-159a demonstrates its potential for use in the treatment of infections due to mycoplasmas and ureaplasmas...
Antimicrobial resistance among isolates of respiratory tract infection pathogens from the southern United States: data from the PROTEKT US surveillance program 2000/2001Ken Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35233 7331, USA
South Med J 96:974-85. 2003....- Comparative in vitro susceptibilities and bactericidal activities of investigational fluoroquinolone ABT-492 and other antimicrobial agents against human mycoplasmas and ureaplasmasKen B Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
Antimicrob Agents Chemother 47:3973-5. 2003..ABT-492 MICs were < or =1 microg/ml, and the agent was bactericidal against selected isolates of M. pneumoniae and M. hominis. ABT-492 has potential for treatment of infections due to these microorganisms... - Dissemination of macrolide-resistant Streptococcus pneumoniae isolates containing both erm(B) and mef(A) in South KoreaKen B Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
J Clin Microbiol 41:5787-91. 2003..1%) contained mef(A) and erm(B). Nineteen isolates containing mef(A) and erm(B) belonged to serotype 19F, and seven isolates were identical to the Taiwan(19F)-14 clone... - Effect of cranberry extract on bacteriuria and pyuria in persons with neurogenic bladder secondary to spinal cord injuryKen B Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 7331, USA
J Spinal Cord Med 27:35-40. 2004..To determine whether antibacterial effects of cranberry extract will reduce or eliminate bacteriuria and pyuria in persons with spinal cord injury (SCI)... - Mycoplasma pneumoniae and its role as a human pathogenKen B Waites
Department of Pathology, WP 230, University of Alabama at Birmingham, 619 19th St South, Birmingham, AL 35249, USA
Clin Microbiol Rev 17:697-728, table of contents. 2004..As more is learned about the pathogenesis and immune response elicited by M. pneumoniae, improvement in methods for diagnosis and prevention of disease due to this organism may occur... - Microbiology of the urethra and perineum and its relationship to bacteriuria in community-residing men with spinal cord injuryKen B Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
J Spinal Cord Med 27:448-52. 2004..We performed a prospective study of bacterial flora of the urethra and perineum in men with and without bacteriuria to understand more completely the relationship between bacterial colonization and invasion of the urinary tract... - Comparative in vitro activities of investigational peptide deformylase inhibitor NVP LBM-415 and other agents against human mycoplasmas and ureaplasmasKen B Waites
Department of Pathology, WP 230, 619 19th Street South, Birmingham, AL 35249, USA
Antimicrob Agents Chemother 49:2541-2. 2005..LBM-415 was active against M. pneumoniae (MICs, <or=0.008 microg/ml). It showed no activity against M. hominis and M. fermentans and modest activity against Ureaplasma spp... - Mycoplasmas and ureaplasmas as neonatal pathogensKen B Waites
Department of Pathology, University of Alabama, Birmingham, Alabama 35249, USA
Clin Microbiol Rev 18:757-89. 2005.... - Evaluation of 3 methods of bladder irrigation to treat bacteriuria in persons with neurogenic bladderKen B Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Spinal Cord Med 29:217-26. 2006.... - Antimicrobial susceptibility among pathogens collected from hospitalized patients in the United States and in vitro activity of tigecycline, a new glycylcycline antimicrobialKen B Waites
Section of Clinical Microbiology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
Antimicrob Agents Chemother 50:3479-84. 2006.... - Revaccination of adults with spinal cord injury using the 23-valent pneumococcal polysaccharide vaccineKen B Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
J Spinal Cord Med 31:53-9. 2008..This study was undertaken to determine the effect of revaccination with the pneumococcal vaccine on the immune response and the frequency of adverse reactions in this population... - New concepts of Mycoplasma pneumoniae infections in childrenKen B Waites
Department of Pathology, University of Alabama at Birmingham, P230 West Pavilion, Birmingham, AL 35233, USA
Pediatr Pulmonol 36:267-78. 2003 - Detection of Chlamydia trachomatis endocervical infections by ligase chain reaction versus ACCESS Chlamydia antigen assayK B Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35233 7331, USA
J Clin Microbiol 37:3072-3. 1999..ACCESS had a sensitivity of 83.9%, a specificity of 99.7%, a positive predictive value of 96.3%, and a negative predictive value of 98.5%... - Comparative in vitro activities of four new fluoroquinolones against Streptococcus pneumoniae determined by EtestK Waites
Department of Pathology, University of Alabama at Birmingham 35233 7331, USA
Int J Antimicrob Agents 9:215-8. 1998..Two isolates, both serotype 6, with high-level quinolone resistance (> or = 8 micrograms/ml) were detected. The Etest is a practical means for determining S. pneumoniae susceptibilities to new fluoroquinolones... - Bacteremia after spinal cord injury in initial versus subsequent hospitalizationsK B Waites
Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham, USA
J Spinal Cord Med 24:96-100. 2001..The increase in drug-resistant bacteria in recent years underscores the importance of gathering accurate microbiological information... - Direct susceptibility testing with positive BacT/Alert blood cultures by using MicroScan overnight and rapid panelsK B Waites
Department of Pathology, University of Alabama at Birmingham, 35233, USA
J Clin Microbiol 36:2052-6. 1998..When discrepant results occur with direct-susceptibility testing, they are more likely to show false susceptibility than false resistance... - Evaluation of BacT/ALERT system for detection of Mycoplasma hominis in simulated blood culturesK B Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 7331, USA
J Clin Microbiol 39:4328-31. 2001..hominis and that specialized media and incubation conditions designed for optimum cultivation of mycoplasmas should be employed when this organism is suspected on clinical grounds... - Use of clindamycin disks To detect macrolide resistance mediated by ermB and mefE in Streptococcus pneumoniae isolates from adults and childrenK Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Clin Microbiol 38:1731-4. 2000..Macrolide resistance mediated by ermB is usually of greater magnitude than that due to mefE. Clinical studies are needed to determine the significance of high- versus low-level macrolide resistance in S. pneumoniae... - In vitro susceptibilities of Mycoplasma hominis to six fluoroquinolones as determined by E testK B Waites
Departments of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
Antimicrob Agents Chemother 43:2571-3. 1999..25; and ciprofloxacin, 0.5. Increasing the amount of inoculum or incubation in CO(2) elevated MICs by </=1 dilution. E tests produce fluoroquinolone MICs comparable to those obtained by agar and microbroth dilution for M. hominis... - In vitro activities of ABT-773 and other antimicrobials against human mycoplasmasKen B Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
Antimicrob Agents Chemother 47:39-42. 2003..pneumoniae and 0.25 microg/ml for M. fermentans, but they were several dilutions higher for M. hominis and Ureaplasma spp. ABT-773 has great potential for further study for the treatment of infections due to mycoplasmas and ureaplasmas... - Inhibitory and bactericidal activities of gemifloxacin and other antimicrobials against Mycoplasma pneumoniaeKen B Waites
Department of Pathology, WP 230, University of Alabama at Birmingham, 619n 19th Street South, Birmingham, AL 35249, USA
Int J Antimicrob Agents 21:574-7. 2003..MBCs for gemifloxacin were predominantly within 2-4 times the corresponding MIC values, indicating a bactericidal effect... 
Emerging macrolide resistance in Mycoplasma pneumoniae in children: detection and characterization of resistant isolatesXiao Li
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
Pediatr Infect Dis J 28:693-6. 2009..A rapid technique to identify macrolide-resistant M. pneumoniae is needed to guide management of patients with community-acquired respiratory infections...- Genetic relatedness of levofloxacin-nonsusceptible Streptococcus pneumoniae isolates from North AmericaCrystal N Johnson
Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
J Clin Microbiol 41:2458-64. 2003..However, seven LNSP were found to be related to three international clones by PFGE... - In vitro susceptibilities to and bactericidal activities of garenoxacin (BMS-284756) and other antimicrobial agents against human mycoplasmas and ureaplasmasKen B Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
Antimicrob Agents Chemother 47:161-5. 2003..hominis by measurement of minimal bactericidal activities and by time-kill studies. Further study of garenoxacin is required, as it has great potential for use in the treatment of infections due to mycoplasmas and ureaplasmas... - Characterization of ureaplasmas isolated from preterm infants with and without bronchopulmonary dysplasiaBrenda Katz
Department of Pathology, University of Alabama at Birmingham, 35249-7331, USA
J Clin Microbiol 43:4852-4. 2005..urealyticum. U. parvum was detected more often than U. urealyticum. There was no significant difference or trend in the prevalence of either species between infants with or without bronchopulmonary dysplasia when isolated alone... - Active surveillance to determine the impact of methicillin-resistant Staphylococcus aureus colonization on patients in intensive care units of a Veterans Affairs Medical CenterMukesh Patel
Birmingham Veterans Affairs Medical Center, Birmingham, Alabama, USA
Infect Control Hosp Epidemiol 29:503-9. 2008..We sought to describe the impact of MRSA colonization on patients admitted to intensive care units (ICUs) in the Birmingham Veterans Affairs Medical Center (VAMC)... - USA300 genotype community-associated methicillin-resistant Staphylococcus aureus as a cause of surgical site infectionsMukesh Patel
Department of Medicine, University of Alabama at Birmingham, THT 229, 1530 3rd Avenue South, Birmingham, AL 35294 0006, USA
J Clin Microbiol 45:3431-3. 2007..CA-MRSA has become a prominent cause of SSI at our institution... - Dissemination of community-associated methicillin-resistant Staphylococcus aureus in a tertiary care hospitalMukesh Patel
Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, 35294 0006, USA
South Med J 101:40-5. 2008..The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) was investigated at a tertiary care hospital, and relationship was made between the clinical and genetic definitions of community- and healthcare-associated MRSA... - New insights into the pathogenesis and detection of Mycoplasma pneumoniae infectionsKen B Waites
University of Alabama at Birmingham, WP 230, 619 19th Street South, Birmingham, AL 35249, USA
Future Microbiol 3:635-48. 2008.... - Congenital and opportunistic infections: Ureaplasma species and Mycoplasma hominisKen B Waites
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
Semin Fetal Neonatal Med 14:190-9. 2009.... - Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101Ken B Waites
Department of Pathology, 619 19th Street South, WP 230, University of Alabama at Birmingham, Birmingham, AL 35249, USA
Antimicrob Agents Chemother 53:2139-41. 2009..All isolates, including two macrolide-resistant M. pneumoniae isolates, were inhibited by CEM-101 at < or = 0.5 microg/ml, making CEM-101 the most potent compound tested... - The role of Mycoplasma in upper respiratory infectionsKen B Waites
Department of Pathology, University of Alabama at Birmingham, WP 230, 619 19th Street South, Birmingham, AL 35249, USA
Curr Infect Dis Rep 11:198-206. 2009..pneumoniae in upper respiratory tract infections; a brief discussion of its cell biology, pathogenic mechanisms, and epidemiology; and recommendations for laboratory diagnosis and management... - The use of a biodegradable, load-bearing scaffold as a carrier for antibiotics in an infected open fracture modelRena L Stewart
Division of Orthopaedics, University of Alabama at Birmingham, Birmingham, AL 35233 3409, USA
J Orthop Trauma 24:587-91. 2010..This study investigates the use of such scaffolds with gentamicin (along with bone morphogenetic protein) in an infected rat open fracture model to decrease osteomyelitis and promote fracture healing... - Fusobacterium necrophorum bacteremic tonsillitis: 2 Cases and a review of the literatureRobert M Centor
Department of Internal Medicine, University of Alabama at Birmingham, Huntsville, 35801, USA
Anaerobe 16:626-8. 2010..necrophorum. Recognition of such patients might prevent Lemierre syndrome... - Ureaplasma infection and neonatal lung diseaseRobert L Schelonka
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA
Semin Perinatol 31:2-9. 2007.... - Prevalence of inducible clindamycin resistance among community- and hospital-associated Staphylococcus aureus isolatesMukesh Patel
Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, THT 229, 1530 3rd Avenue South, Birmingham, AL 35294 0006, USA
J Clin Microbiol 44:2481-4. 2006..Due to the low prevalence of MLSBi among CA-MRSA isolates, clindamycin remains a useful option for outpatient therapy... - Critical appraisal of the role of Ureaplasma in the development of bronchopulmonary dysplasia with metaanalytic techniquesRobert L Schelonka
Department of Pediatrics University of Alabama at Birmingham, Birmingham, AL, USA
Pediatr Infect Dis J 24:1033-9. 2005.... - Relative fitness of fluoroquinolone-resistant Streptococcus pneumoniaeCrystal N Johnson
University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
Emerg Infect Dis 11:814-20. 2005..However, the strain was equally able to cause competitive or noncompetitive lung infections as well as EF3030... - Nosocomial spread of Enterococcus faecium resistant to vancomycin and linezolid in a tertiary care medical centerThomas E Dobbs
Department of Medicine, University of Alabama at Birmingham, 619 South 19th St, 35249, USA
J Clin Microbiol 44:3368-70. 2006..Epidemiologic investigation and pulsed-field gel electrophoresis patterns indicated a clonal outbreak related to nosocomial spread... - In vitro comparison of agar and microbroth dilution methods for determination of MICs for Mycoplasma hominisNicholaus J Hilliard
Department of Pathology, University of Alabama at Birmingham, WP 230, 619 19th St S. Birmingham, AL 35249, USA
J Microbiol Methods 60:285-8. 2005..Both methods provide reproducible results. Agar dilution tends to yield higher MIC values for some drugs... - Detection and characterization of human Ureaplasma species and serovars by real-time PCRLi Xiao
Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
J Clin Microbiol 48:2715-23. 2010..These assays provide quick and reliable means for investigating the epidemiology and pathogenicity of ureaplasmas at the serovar level... - In vitro activity of ertapenem (MK-0826) against multi-drug resistant Streptococcus pneumoniae compared with 13 other antimicrobialsNicholaus J Hilliard
Department of Pathology, University of Alabama at Birmingham, WP P230N, 619 19th Street South, 35249-7331, USA
Int J Antimicrob Agents 20:136-40. 2002..pneumoniae, including infections caused by organisms with reduced susceptibilities to other antimicrobial agents... - Rapid multiplex assay for serotyping pneumococci with monoclonal and polyclonal antibodiesJigui Yu
Department of Pathology, University of Alabama at Birmingham, AL, USA
J Clin Microbiol 43:156-62. 2005..This system should be very useful in serotyping clinical isolates for evaluating pneumococcal vaccine efficacy... - Epidemiology, clinical manifestations, pathogenesis and laboratory detection of Mycoplasma pneumoniae infectionsTHOMAS PRESCOTT ATKINSON
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA
FEMS Microbiol Rev 32:956-73. 2008.... - Bacillus cereus bacteremia in a preterm neonateNicholaus J Hilliard
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
J Clin Microbiol 41:3441-4. 2003.... - Nosocomial ventriculitis due to Roseomonas gilardii complicating subarachnoid haemorrhageJason S Nolan
Department of Pathology, University of Alabama at Birmingham, WP 230, 619 19th Street South, Birmingham, AL 35249, USA
J Infect 50:244-51. 2005.... - Effective communication of antimicrobial susceptibility data by pathologists to cliniciansKen B Waites
Department of Pathology, University of Alabama, Birmingham, AL, USA
Adv Exp Med Biol 563:165-77. 2005.... - Prevalence of plasmid-mediated quinolone resistanceGeorge A Jacoby
Infectious Disease Department, Lahey Clinic, Burlington, Massachusetts, USA
Antimicrob Agents Chemother 47:559-62. 2003..This plasmid and one carrying the complete microcin B17 operon slightly decreased sparfloxacin susceptibility but had a much less protective effect than pMG252. Plasmid-mediated quinolone resistance was thus rare in the sample examined... - Bactericidal activity of levofloxacin against Mycoplasma pneumoniaeLynn B Duffy
J Antimicrob Chemother 52:527-8. 2003
Research Grants
- Molecular Epidemiology, Virulence, and Genomic Characterization of UreaplasmasKen Waites; Fiscal Year: 2007....