Research Topics
Species | Jean Wactawski-WendeSummaryAffiliation: University at Buffalo Country: USA Publications
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Publications
Calcium plus vitamin D supplementation and the risk of colorectal cancerJean Wactawski-Wende
Department of Social and Preventive Medicine, University at Buffalo, 270 Farber Hall, Buffalo, NY 14214, USA
N Engl J Med 354:684-96. 2006..However, randomized-trial evidence that calcium with vitamin D supplementation is beneficial in the primary prevention of colorectal cancer is lacking...
BioCycle study: design of the longitudinal study of the oxidative stress and hormone variation during the menstrual cycleJean Wactawski-Wende
Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY 14214, USA
Paediatr Perinat Epidemiol 23:171-84. 2009..This report describes the study design, baseline characteristics and visit completion rate for the BioCycle study...- The association between osteoporosis and alveolar crestal height in postmenopausal womenJean Wactawski-Wende
Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY 14214, USA
J Periodontol 76:2116-24. 2005..Evidence supporting an association between osteoporosis and loss of alveolar crestal bone is limited. This study investigated that association in a large cohort of postmenopausal women... - Factors associated with treatment initiation after osteoporosis screeningRenee M Brennan
Department of Social and Preventive Medicine, University at Buffalo, 3435 Main Street, Buffalo, NY 14214, USA
Am J Epidemiol 160:475-83. 2004..In this study, approximately half of the women with osteoporosis initiated treatment after screening. Disease severity, medical care frequency, education, income, and physician type predicted treatment initiation... - Periodontal disease and the incidence of tooth loss in postmenopausal womenMine Tezal
Department of Oral Biology, University at Buffalo, Buffalo, NY, USA
J Periodontol 76:1123-8. 2005..The aim of this cohort study was to determine the extent of the association between baseline periodontal status and incident tooth loss in a population of postmenopausal women... - Changes in vitamin D supplement use and baseline plasma 25-hydroxyvitamin D concentration predict 5-y change in concentration in postmenopausal womenMelissa A Kluczynski
Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, The State University of New York, Buffalo, NY, USA
J Nutr 142:1705-12. 2012..These data also suggest that this is especially true among aging women with inadequate 25(OH)D (e.g., <50 nmol/L)... - Bacterial species in subgingival plaque and oral bone loss in postmenopausal womenRenee M Brennan
Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, State University of New York, Buffalo, NY 14212, USA
J Periodontol 78:1051-61. 2007.... - Young women with type 1 diabetes have lower bone mineral density that persists over timeLucy D Mastrandrea
Department of Pediatrics, University at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York, USA
Diabetes Care 31:1729-35. 2008..We here report 2-year follow-up BMD data in this cohort to determine the natural history of BMD in young women with and without diabetes... - Intraindividual variation in plasma 25-hydroxyvitamin D measures 5 years apart among postmenopausal womenJennifer E Meng
Department of Social and Preventive Medicine, University at Buffalo, The State University of New York, Buffalo, NY 14214 8001, USA
Cancer Epidemiol Biomarkers Prev 21:916-24. 2012..Current literature examining associations between vitamin D and chronic disease generally use a single assessment of 25-hydroxyvitamin D [25(OH)D], assuming the 25(OH)D concentration of an individual is consistent over time... - Clinical attachment loss, systemic bone density, and subgingival calculus in postmenopausal womenRenee M Brennan
Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, State University of New York, Buffalo, NY 14214, USA
J Periodontol 78:2104-11. 2007..We investigated these associations in a relatively large study while evaluating potential confounding factors and effect modification by subgingival calculus and age... - Analytical and biological variation of biomarkers of oxidative stress during the menstrual cycleRichard W Browne
Department of Biotechnical and Clinical Laboratory Sciences, University at Buffalo, State University of New York, NY 14214, USA
Biomarkers 13:160-83. 2008..These results provide important initial information on the variability of biomarkers of oxidative stress, antioxidant defence and micronutrients across the menstrual cycle... - Clinical and community risk models of incident tooth loss in postmenopausal women from the Buffalo Osteo Perio StudyChristopher Bole
Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, State University of New York, Buffalo, NY, USA
Community Dent Oral Epidemiol 38:487-97. 2010.... - Energy expenditure and plasma F2-isoprostanes across the menstrual cycleCarole B Rudra
Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY 14214, USA
Med Sci Sports Exerc 43:785-92. 2011..Sparse evidence suggests that hormones that fluctuate during the menstrual cycle, particularly estrogens, may influence concentrations of oxidative biomarkers and their relation to energy expenditure... - Predictors of serum 25-hydroxyvitamin D concentrations among postmenopausal women: the Women's Health Initiative Calcium plus Vitamin D clinical trialAmy E Millen
Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, 270 Farber Hall, Buffalo, NY 14214 8001, USA
Am J Clin Nutr 91:1324-35. 2010.... - Health behaviors and other characteristics of women on hormone therapy: results from the Third National Health and Nutrition Examination Survey, 1988-1994Renee M Brennan
Department of Social and Preventive Medicine, University at Buffalo, The State University of New York, Buffalo, NY 14214 3000, USA
Menopause 11:536-42. 2004..To examine the prevalence of hormone therapy (HT) use and compare demographic characteristics, health behaviors, and health indicators between current HT users and never-users in a nationally representative sample of postmenopausal women... - Supragingival plaque may modify the effects of subgingival bacteria on attachment lossMine Tezal
Department of Oral Biology, State University of New York, Buffalo, NY 14214, USA
J Periodontol 77:808-13. 2006..This study evaluates the role of supragingival plaque level on the relationship between subgingival microorganisms and the risk of attachment loss... - Duration of physical activity and serum 25-hydroxyvitamin D status of postmenopausal womenMelissa A Kluczynski
Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, NY 14214 8001, USA
Ann Epidemiol 21:440-9. 2011..To investigate whether the association between physical activity and serum 25-hydroxyvitamin D (25(OH)D) concentrations is independent of sun exposure, body size, and other potential explanatory variables... - Associations between smoking and tooth loss according to the reason for tooth loss: the Buffalo OsteoPerio StudyXiaodan Mai
Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, The State University of New York, Buffalo, NY 14214, USA
J Am Dent Assoc 144:252-65. 2013..Smoking is associated with tooth loss. However, smoking's relationship to the specific reason for tooth loss in postmenopausal women is unknown... - Predictors of change in calcium intake in postmenopausal women after osteoporosis screeningKatherine M McLeod
Department of Exercise and Nutrition Science, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY 14214, USA
J Nutr 137:1968-73. 2007..This study provided evidence that the results of osteoporosis DXA screening influence postmenopausal women's decisions to increase calcium intake... - Ascorbic acid status in postmenopausal women with hormone replacement therapyShiu Ming Kuo
Department of Physical Therapy, Exercise and Nutrition Sciences, UB State University of New York, Buffalo, NY 14214, USA
Maturitas 41:45-50. 2002..This is a pilot study to examine the relation between hormone replacement therapy (HRT) and plasma ascorbic acid levels among a group of healthy non-smoking postmenopausal women... - Temporal trends in the rates of trial of labor in low-risk pregnancies and their impact on the rates and success of vaginal birth after cesarean deliveryJohn Yeh
Department of Gynecology Obstetrics, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14222, USA
Am J Obstet Gynecol 194:144. 2006.... 
Chronic periodontitis and the incidence of head and neck squamous cell carcinomaMine Tezal
Department of Oral Diagnostic Sciences, The State University of New York, Buffalo, New York 14214, USA
Cancer Epidemiol Biomarkers Prev 18:2406-12. 2009..These results have implications for practical and safe strategies for prevention, diagnosis, and treatment of HNSCC...- Incident invasive breast cancer, geographic location of residence, and reported average time spent outsideAmy E Millen
Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY 14214 8001, USA
Cancer Epidemiol Biomarkers Prev 18:495-507. 2009..The observed association between time spent outside and breast cancer risk support the hypothesis that vitamin D may protect against breast cancer... - Does low bone mineral density start in post-teenage years in women with type 1 diabetes?Emily Y Liu
The Women and Children s Hospital of Buffalo, Division of Endocrinology Diabetes, Buffalo, New York 14222, USA
Diabetes Care 26:2365-9. 2003.... - The Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) pilot study: methods and participant characteristicsJohn M Violanti
School of Public Health and Health Professions, Department of Social and Preventive Medicine, State University of New York at Buffalo 14214 8001, USA
Ann Epidemiol 16:148-56. 2006..This pilot study was undertaken to establish a methodology and descriptive results for a larger police study... - Changes in 2-hydroxyestrone and 16alpha-hydroxyestrone metabolism with flaxseed consumption: modification by COMT and CYP1B1 genotypeSusan E McCann
Department of Epidemiology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Cancer Epidemiol Biomarkers Prev 16:256-62. 2007..89; Leu/Val, 1.32; and Val/Val, 1.51; P = 0.04, Kruskal-Wallis). Our findings suggest that variation in hormone-related genes may modify the effect of dietary lignan exposures on estrogen metabolism... - Reproductive outcomes in men with prenatal exposure to diethylstilbestrolKimberly M Perez
Department of Social and Preventive Medicine, University of Buffalo, State of New York, Buffalo, New York, USA
Fertil Steril 84:1649-56. 2005.... - Combined postmenopausal hormone therapy and cardiovascular disease: toward resolving the discrepancy between observational studies and the Women's Health Initiative clinical trialRoss L Prentice
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Am J Epidemiol 162:404-14. 2005..These analyses have implications for both the design and the analysis of observational studies... - A prospective study of the effect of hypertension and baseline blood pressure on cognitive decline and dementia in postmenopausal women: the Women's Health Initiative Memory StudyKaren C Johnson
Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennesse 38163, USA
J Am Geriatr Soc 56:1449-58. 2008..To examine the relationship between baseline hypertension, blood pressure, and the development of cognitive decline in participants in the Women's Health Initiative Memory Study (WHIMS)... - Cystatin-C, renal function, and incidence of hip fracture in postmenopausal womenAndrea Z LaCroix
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
J Am Geriatr Soc 56:1434-41. 2008..To evaluate the association between chronic kidney disease and incident hip fracture using serum cystatin-C as a biomarker of renal function calculated without reference to muscle mass... - Lack of a relation between vitamin and mineral antioxidants and bone mineral density: results from the Women's Health InitiativeRandi L Wolf
Program in Nutrition, Department of Health and Behavior Studies, Teachers College, Columbia University, New York, NY 10027, USA
Am J Clin Nutr 82:581-8. 2005..Antioxidant defenses are one possible mechanism for decreasing oxidative damage and its potentially negative effects on age-related bone mass... - Hip bone density predicts breast cancer risk independently of Gail score: results from the Women's Health InitiativeZhao Chen
Division of Epidemiology and Biostatistics, University of Arizona College of Public Health, Tucson, Arizona 85724 5211, USA
Cancer 113:907-15. 2008..The objective of the current study was to investigate whether hip BMD predicts postmenopausal breast cancer risk independently of the Gail score... - Serum 25-hydroxyvitamin D concentrations and risk for hip fracturesJane A Cauley
University of Pittsburgh, Department of Epidemiology, 130 DeSoto Street, Crabtree A524, Pittsburgh, PA 15261, USA
Ann Intern Med 149:242-50. 2008..The relationship between serum 25-hydroxyvitamin D [25(OH) vitamin D] concentration and hip fractures is unclear... - Calcium, vitamin D supplementation, and physical function in the Women's Health InitiativeRobert L Brunner
University of Nevada School of Medicine, PMB 251, MS 145, Reno, NV 89557, USA
J Am Diet Assoc 108:1472-9. 2008..Now we examine whether the treatment affected self-reported physical functioning and objective measures of physical functioning... - Abdominal aortic aneurysm events in the women's health initiative: cohort studyFrank A Lederle
VA Medical Center, Minneapolis, MN 55417, USA
BMJ 337:a1724. 2008..To assess the association between potential risk factors and subsequent clinically important abdominal aortic aneurysm events (repairs and ruptures) in women... - Prior oral contraception and postmenopausal fracture: a Women's Health Initiative observational cohort studyDavid Barad
Obstetrics and Gynecology and Women s Health, Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, New York 10021, USA
Fertil Steril 84:374-83. 2005..To test for the possible association of past oral contraceptive (OC) use and incident fracture after menopause... - Factors associated with 5-year risk of hip fracture in postmenopausal womenJohn Robbins
Department of Internal Medicine, University of California at Davis School of Medicine, Sacramento, CA 95817, USA
JAMA 298:2389-98. 2007..The 329,000 hip fractures that annually occur in the United States are associated with high morbidity, mortality, and cost. Identification of those at high risk is a step toward prevention... - Effects of estrogen with and without progestin and obesity on symptomatic gastroesophageal refluxZongli Zheng
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Gastroenterology 135:72-81. 2008..An association between female hormones and symptomatic gastroesophageal reflux disease (GERD) and may be modified by obesity is suggested but not proven. Factors affecting GERD progression, however, are largely unknown... - Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trialGarnet L Anderson
Fred Hutchinson Cancer Research Center, Seattle, Wash 98109 1024, USA
JAMA 291:1701-12. 2004..Despite decades of use and considerable research, the role of estrogen alone in preventing chronic diseases in postmenopausal women remains uncertain... - Chronic periodontitis and the risk of tongue cancerMine Tezal
Department of Periodontics, State University of New York at Buffalo, NY, USA
Arch Otolaryngol Head Neck Surg 133:450-4. 2007..To assess the association between the history of chronic periodontitis and the risk of tongue cancer... - Combined analysis of Women's Health Initiative observational and clinical trial data on postmenopausal hormone treatment and cardiovascular diseaseRoss L Prentice
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Am J Epidemiol 163:589-99. 2006..An application to postmenopausal hormone treatment effects on coronary heart disease among younger women is also provided... - Calcium plus vitamin D supplementation and the risk of fracturesRebecca D Jackson
Division of Endocrinology, Ohio State University, 485 McCampbell, 1581 Dodd Dr, Columbus, OH 43210, USA
N Engl J Med 354:669-83. 2006..The efficacy of calcium with vitamin D supplementation for preventing hip and other fractures in healthy postmenopausal women remains equivocal... - Low-fat dietary pattern and risk of colorectal cancer: the Women's Health Initiative Randomized Controlled Dietary Modification TrialShirley A A Beresford
Department of Epidemiology, University of Washington, Seattle, WA 98195 7236, USA
JAMA 295:643-54. 2006..Observational studies and polyp recurrence trials are not conclusive regarding the effects of a low-fat dietary pattern on risk of colorectal cancer, necessitating a primary prevention trial... - Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification TrialRoss L Prentice
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Wash 98109, USA
JAMA 295:629-42. 2006..The hypothesis that a low-fat dietary pattern can reduce breast cancer risk has existed for decades but has never been tested in a controlled intervention trial... - Calcium plus vitamin D supplementation and the risk of incident diabetes in the Women's Health InitiativeIan H De Boer
Division of Nephrology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA
Diabetes Care 31:701-7. 2008..We examined the effect of calcium plus vitamin D supplementation on the incidence of drug-treated diabetes in postmenopausal women... - Relation of demographic factors, menstrual history, reproduction and medication use to sex hormone levels in postmenopausal womenAnne McTiernan
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Breast Cancer Res Treat 108:217-31. 2008..These results suggest that while age, oophorectomy status, and NSAID use may be associated with selected sex hormone concentrations, few menstrual or reproductive factors affect endogenous sex hormones in the postmenopausal period... - Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trialSally A Shumaker
Department of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC 27104, USA
JAMA 289:2651-62. 2003..On July 8, 2002, the study drugs, estrogen plus progestin, in the Women's Health Initiative (WHI) trial were discontinued because of certain increased health risks in women receiving combined hormone therapy... - Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trialJane A Cauley
Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
JAMA 290:1729-38. 2003..In the Women's Health Initiative trial of estrogen-plus-progestin therapy, women assigned to active treatment had fewer fractures... - Estrogen plus progestin and colorectal cancer in postmenopausal womenRowan T Chlebowski
Department of Medicine, Harbor UCLA Research and Education Institute, Torrance, Calif 90502, USA
N Engl J Med 350:991-1004. 2004..We analyzed features of the colorectal cancers that developed and their relation to the characteristics of the participants... - Effects of conjugated equine estrogen on risk of fractures and BMD in postmenopausal women with hysterectomy: results from the women's health initiative randomized trialRebecca D Jackson
Division of Endocrinology, Diabetes, and Metabolism, The Ohio State University, Columbus, OH 43210, USA
J Bone Miner Res 21:817-28. 2006..The fracture reduction at the hip did not differ appreciably among risk strata. These data do not support overall benefit over risk, even in women at highest risk for fracture... - Obesity and risk of pancreatic cancer among postmenopausal women: the Women's Health Initiative (United States)J Luo
Institute of Social Development and Public Policy, Beijing Normal University, Beijing, China
Br J Cancer 99:527-31. 2008..Women in the highest quintile of waist-to-hip ratio had 70% (95% confidence interval 10-160%) excess risk of pancreatic cancer compared with women in the lowest quintile... - Usefulness of baseline lipids and C-reactive protein in women receiving menopausal hormone therapy as predictors of treatment-related coronary eventsPaul F Bray
Cardeza Foundation for Hematologic Research and Jefferson Medical College, Philadelphia, Pennsylvania, USA
Am J Cardiol 101:1599-1605. 2008..However, women with favorable lipid levels, especially LDL/HDL cholesterol ratio <2.5, did not have increased risk of coronary heart disease with CEE with or without MPA irrespective of hs-CRP... - Oophorectomy, hormone therapy, and subclinical coronary artery disease in women with hysterectomy: the Women's Health Initiative coronary artery calcium studyMatthew A Allison
University of California San Diego, La Jolla, CA, USA
Menopause 15:639-47. 2008..In this study, we aimed to determine the associations between coronary artery calcium (CAC) and hysterectomy, oophorectomy, and hormone therapy use with a focus on the duration of menopause for which there was no hormone therapy use... - Statin use and incident frailty in women aged 65 years or older: prospective findings from the Women's Health Initiative Observational StudyAndrea Z LaCroix
Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Gerontol A Biol Sci Med Sci 63:369-75. 2008..This study examines associations between current use, duration, and potency of statin medications and incident frailty in initially nonfrail women 65 years old or older... - Associations between age-related nuclear cataract and lutein and zeaxanthin in the diet and serum in the Carotenoids in the Age-Related Eye Disease Study, an Ancillary Study of the Women's Health InitiativeSuzen M Moeller
Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53726 2336, USA
Arch Ophthalmol 126:354-64. 2008..To evaluate associations between nuclear cataract (determined from slitlamp photographs between May 2001 and January 2004) and lutein and zeaxanthin in the diet and serum in patients between 1994 and 1998 and macula between 2001 and 2004... - Estrogen plus progestin and breast cancer detection by means of mammography and breast biopsyRowan T Chlebowski
Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
Arch Intern Med 168:370-7; quiz 345. 2008..The effect of combined hormone therapy on breast cancer detection is not established... - Low-fat dietary pattern and risk of treated diabetes mellitus in postmenopausal women: the Women's Health Initiative randomized controlled dietary modification trialLesley F Tinker
Women s Health Initiative, Fred Hutchinson Cancer Research Center, PO Box 19024, Mail Stop M3 A410, Seattle, WA 98109, USA
Arch Intern Med 168:1500-11. 2008..This study was undertaken to assess the effects of a low-fat dietary pattern on incidence of treated diabetes among generally healthy postmenopausal women...
Research Grants
- BONE MINERAL DENSITY AS A PREDICTOR OF PERIODONTITISJean Wactawski Wende; Fiscal Year: 2005..Hence once the relationship is established, modalities effective in the prevention and treatment of osteoporosis may prove useful for prevention and treatment of periodontitis and subsequent tooth loss. ..