Research Topics
Species | Vladyslav V VyazovskiySummaryAffiliation: University of Wisconsin Country: USA Publications
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Detail Information
Publications
Sleep in Kcna2 knockout miceChristopher L Douglas
Department of Psychiatry, University of Wisconsin, Madison, WI, 53719, USA
BMC Biol 5:42. 2007..To address this issue, we studied sleep in Kcna2 knockout (KO) mice. Kcna2 codes for Kv1.2, the alpha subunit of a Shaker-like voltage-dependent potassium channel with high expression in the mammalian thalamocortical system...- Electrophysiological correlates of sleep homeostasis in freely behaving ratsVladyslav V Vyazovskiy
Department of Psychiatry, University of Wisconsin Madison, Madison, WI, USA
Prog Brain Res 193:17-38. 2011..Taken together, these data suggest that homeostatic changes in sleep EEG are the result of altered neuronal firing and synchrony, which in turn arise from changes in functional neuronal connectivity... - Cortical firing and sleep homeostasisVladyslav V Vyazovskiy
Department of Psychiatry, University of Wisconsin Madison, Madison, WI 53719, USA
Neuron 63:865-78. 2009..Changes in firing patterns in NREM sleep correlate with changes in slow-wave activity, a marker of sleep homeostasis. Thus, the systematic increase of firing during wakefulness is counterbalanced by staying asleep... - Sleep homeostasis and cortical synchronization: III. A high-density EEG study of sleep slow waves in humansBrady A Riedner
Department of Psychiatry, University of Wisconsin, Madison, WI 53719, USA
Sleep 30:1643-57. 2007..Here, we investigated the model's predictions in humans by using all-night high-density (hd)-EEG recordings to explore slow-wave parameters over the entire cortical mantle... - Local sleep in awake ratsVladyslav V Vyazovskiy
Department of Psychiatry, University of Wisconsin Madison, Madison, 6001 Research Park Boulevard, Wisconsin 53719, USA
Nature 472:443-7. 2011..Thus, although both the EEG and behaviour indicate wakefulness, local populations of neurons in the cortex may be falling asleep, with negative consequences for performance... - Long-term homeostasis of extracellular glutamate in the rat cerebral cortex across sleep and waking statesMichael B Dash
Department of Psychiatry, and Neuroscience Training Program, University of Wisconsin Madison, Madison, WI 53719, USA
J Neurosci 29:620-9. 2009..These results provide evidence for a long-term homeostasis of extracellular glutamate across sleep-waking states... - Triggering slow waves during NREM sleep in the rat by intracortical electrical stimulation: effects of sleep/wake history and background activityVladyslav V Vyazovskiy
Dept of Psychiatry, University of Wisconsin Madison, 6001 Research Park Blvd, Madison, WI 53719, USA
J Neurophysiol 101:1921-31. 2009..These results show that in the rat a volley of electrical activity that is sufficiently strong to excite and recruit a large cortical neuronal population is capable of inducing slow waves during natural sleep... - Effects of skilled training on sleep slow wave activity and cortical gene expression in the ratErin C Hanlon
Department of Psychiatry, University of Wisconsin Madison, Madison, WI 53719, USA
Sleep 32:719-29. 2009.... - Homeostatic regulation of sleep in the white-crowned sparrow (Zonotrichia leucophrys gambelii)Stephany G Jones
Neuroscience Training Program, University of Wisconsin Madison, USA
BMC Neurosci 9:47. 2008..To accomplish this goal, we investigated amount of sleep, sleep time course, and measures of sleep intensity in 6 birds during baseline sleep and during recovery sleep following 6 hours of sleep deprivation... - Sleep homeostasis and cortical synchronization: II. A local field potential study of sleep slow waves in the ratVladyslav V Vyazovskiy
Department of Psychiatry, University of Wisconsin, Madison, WI 53719, USA
Sleep 30:1631-42. 2007..Here we tested the model predictions by obtaining LFP recordings from the rat cerebral cortex and comparing conditions of high homeostatic sleep pressure (early sleep) and low homeostatic sleep pressure (late sleep)... 
Synaptic potentiation and sleep need: clues from molecular and electrophysiological studiesErin C Hanlon
Department of Psychiatry, University of Wisconsin Madison, Madison, WI 53719, USA
Curr Top Med Chem 11:2472-82. 2011..We end by discussing current challenges to this hypothesis and future research directions...- A causal role for brain-derived neurotrophic factor in the homeostatic regulation of sleepUgo Faraguna
Department of Psychiatry, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
J Neurosci 28:4088-95. 2008..These effects were also reversible and specific for NREM sleep. These results show a causal link between BDNF expression during wakefulness and subsequent sleep regulation... - Unilateral cortical spreading depression affects sleep need and induces molecular and electrophysiological signs of synaptic potentiation in vivoUgo Faraguna
Department of Psychiatry, University of Wisconsin Madison, 6001 Research Park Boulevard, Madison WI 53719, USA
Cereb Cortex 20:2939-47. 2010..These effects are consistent with an increase in synaptic strength triggered by CSD, although nonphysiological phenomena associated with CSD may also play a role... - Sleep homeostasis in the rat is preserved during chronic sleep restrictionSusan Leemburg
Department of Psychiatry, University of Wisconsin, Madison, 53719, USA
Proc Natl Acad Sci U S A 107:15939-44. 2010..Analysis of cumulative slow wave energy demonstrated that the loss of SWA during SR was compensated by the end of the second recovery day. Thus, the homeostatic regulation of sleep is preserved under conditions of chronic SR... 
Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleepVladyslav V Vyazovskiy
Department of Psychiatry, University of Wisconsin Madison, 6001 Research Park Blvd, Madison, Wisconsin 53719, USA
Nat Neurosci 11:200-8. 2008..Thus, wakefulness appears to be associated with net synaptic potentiation, whereas sleep may favor global synaptic depression, thereby preserving an overall balance of synaptic strength...- Regional slow waves and spindles in human sleepYuval Nir
Department of Psychiatry, University of Wisconsin Madison, Madison, WI 53719, USA
Neuron 70:153-69. 2011..Thus, intracerebral communication during sleep is constrained because slow and spindle oscillations often occur out-of-phase in different brain regions...