Christopher Vulpe

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Functional profiling discovers the dieldrin organochlorinated pesticide affects leucine availability in yeast
    Brandon D Gaytán
    Department of Nutritional Science and Toxicology, University of California, Berkeley, California 94720, USA
    Toxicol Sci 132:347-58. 2013
  2. pmc A genome-wide screen identifies yeast genes required for tolerance to technical toxaphene, an organochlorinated pesticide mixture
    Brandon D Gaytán
    Department of Nutritional Science and Toxicology, University of California, Berkeley, Berkeley, California, United States of America
    PLoS ONE 8:e81253. 2013
  3. pmc Genome-Wide Functional and Stress Response Profiling Reveals Toxic Mechanism and Genes Required for Tolerance to Benzo[a]pyrene in S. cerevisiae
    Sean Timothy Francis O'Connor
    Vulpe Laboratory, Graduate Group in Environmental Health Sciences, University of California Berkeley, CA, USA
    Front Genet 3:316. 2012
  4. pmc Genome-wide functional profiling reveals genes required for tolerance to benzene metabolites in yeast
    Matthew North
    Department of Nutritional Science and Toxicology, University of California, Berkeley, California, United States of America
    PLoS ONE 6:e24205. 2011
  5. pmc Modulation of Ras signaling alters the toxicity of hydroquinone, a benzene metabolite and component of cigarette smoke
    Matthew North
    Department of Nutritional Science and Toxicology, University of California, Berkeley, California 94720, USA
    BMC Cancer 14:6. 2014
  6. pmc SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosis
    Clare C Constantine
    The Centre for Molecular, Environmental, Genetic and Analytic MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    BMC Med Genet 9:18. 2008
  7. pmc Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae
    William J Jo
    Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California 94720, USA
    BMC Genomics 10:130. 2009
  8. pmc Linking mechanistic and behavioral responses to sublethal esfenvalerate exposure in the endangered delta smelt; Hypomesus transpacificus (Fam. Osmeridae)
    Richard E Connon
    School of Veterinary Medicine, Department of Anatomy, Physiology and Cell Biology, University of California, Davis, California 95616, USA
    BMC Genomics 10:608. 2009
  9. pmc Systems biology of human benzene exposure
    Luoping Zhang
    Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA 94720 7356, USA
    Chem Biol Interact 184:86-93. 2010

Research Grants

Collaborators

  • Luoping Zhang
  • Martyn T Smith
  • Roel Vermeulen
  • Cliona M McHale
  • Stephen M Rappaport
  • Min Shen
  • Qing Lan
  • Christine F Skibola
  • Reuben Thomas
  • Matthew North
  • Brandon D Gaytán
  • Alex V Loguinov
  • Alexandre Loguinov
  • Nancy D Denslow
  • Jan Michael Lerot
  • Sean Timothy Francis O'Connor
  • Richard E Connon
  • William J Jo
  • Clare C Constantine
  • Joe Shuga
  • Kevin Shannon
  • Michele Fromowitz
  • Xenia Peñate
  • Stephen R Lantz
  • Sebastián Chávez
  • Jiaqi Lan
  • April Z Gu
  • Inna Gerlovina
  • Alan E Hubbard
  • Vickram J Tandon
  • Alex Loguinov
  • Janice Pfeiff
  • Guri Giaever
  • Patricia Holman
  • Juergen Geist
  • Alexander V Loguinov
  • Adam P Arkin
  • Eric Oh
  • Leandro S D'Abronzo
  • Jeung Hyoun Kim
  • Inge Werner
  • Henri Wintz
  • Corey Nislow
  • Daniel Jaramillo
  • Gregory J Anderson
  • D R English
  • Katrina J Allen
  • A E Nisselle
  • Lyle C Gurrin
  • M C Southey
  • A J Nicoll
  • Melanie Bahlo
  • L W Powell
  • Dorota M Gertig
  • Christine E McLaren
  • A Fletcher
  • J L Hopper
  • J K Olynyk
  • N J Osborne
  • G G Giles
  • Susan M Forrest
  • M B Delatycki

Detail Information

Publications10

  1. pmc Functional profiling discovers the dieldrin organochlorinated pesticide affects leucine availability in yeast
    Brandon D Gaytán
    Department of Nutritional Science and Toxicology, University of California, Berkeley, California 94720, USA
    Toxicol Sci 132:347-58. 2013
    ..Many yeast genes described in this study have human orthologs that may modulate dieldrin toxicity in humans...
  2. pmc A genome-wide screen identifies yeast genes required for tolerance to technical toxaphene, an organochlorinated pesticide mixture
    Brandon D Gaytán
    Department of Nutritional Science and Toxicology, University of California, Berkeley, Berkeley, California, United States of America
    PLoS ONE 8:e81253. 2013
    ..Many of the yeast genes identified in this study have human homologs, warranting further investigations into the potentially conserved mechanisms of toxaphene toxicity. ..
  3. pmc Genome-Wide Functional and Stress Response Profiling Reveals Toxic Mechanism and Genes Required for Tolerance to Benzo[a]pyrene in S. cerevisiae
    Sean Timothy Francis O'Connor
    Vulpe Laboratory, Graduate Group in Environmental Health Sciences, University of California Berkeley, CA, USA
    Front Genet 3:316. 2012
    ..In particular, we identified several transporters with human orthologs (solute carrier family 22) which may play a role in mammalian systems...
  4. pmc Genome-wide functional profiling reveals genes required for tolerance to benzene metabolites in yeast
    Matthew North
    Department of Nutritional Science and Toxicology, University of California, Berkeley, California, United States of America
    PLoS ONE 6:e24205. 2011
    ..Many of the yeast genes identified have human orthologs that may modulate human benzene toxicity in a similar manner and could play a role in benzene exposure-related disease...
  5. pmc Modulation of Ras signaling alters the toxicity of hydroquinone, a benzene metabolite and component of cigarette smoke
    Matthew North
    Department of Nutritional Science and Toxicology, University of California, Berkeley, California 94720, USA
    BMC Cancer 14:6. 2014
    ..Increased Ras signaling is implicated as a causal factor in the increased pre-disposition to leukemia of individuals with mutations in NF1...
  6. pmc SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosis
    Clare C Constantine
    The Centre for Molecular, Environmental, Genetic and Analytic MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    BMC Med Genet 9:18. 2008
    ..We report our experience of selecting tag SNPs in 35 genes involved in iron metabolism in a cohort study seeking to discover genetic modifiers of hereditary hemochromatosis...
  7. pmc Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae
    William J Jo
    Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California 94720, USA
    BMC Genomics 10:130. 2009
    ..The resulting analysis provides a global perspective on the cellular processes involved in iron metabolism...
  8. pmc Linking mechanistic and behavioral responses to sublethal esfenvalerate exposure in the endangered delta smelt; Hypomesus transpacificus (Fam. Osmeridae)
    Richard E Connon
    School of Veterinary Medicine, Department of Anatomy, Physiology and Cell Biology, University of California, Davis, California 95616, USA
    BMC Genomics 10:608. 2009
    ..Selected genes were further investigated as molecular biomarkers using quantitative PCR analyses...
  9. pmc Systems biology of human benzene exposure
    Luoping Zhang
    Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA 94720 7356, USA
    Chem Biol Interact 184:86-93. 2010
    ....

Research Grants13

  1. HEPHAESTIN--A COPPER PROTEIN INVOLVED IN IRON METABOLISM
    Christopher Vulpe; Fiscal Year: 1999
    ..Understanding of the basic systems of iron transport by the mammalian organism is necessary to understand the etiology of iron deficiency anemia and iron overload in humans and devise effective therapies. ..
  2. Hephaestin: A Copper Protein Involved in Iron Metabolism
    Christopher Vulpe; Fiscal Year: 2005
    ..Iron transport assays using a buffer system that allows us to very tightly control the amount of ferrous and ferric iron will allow us to distinguish between these possibilities. ..
  3. MOLECULAR APPROACHES TO BASOLATERAL GI IRON TRANSPORT
    Christopher Vulpe; Fiscal Year: 2004
    ....
  4. Hephaestin: A Copper Protein Involved in Iron Metabolism
    Christopher Vulpe; Fiscal Year: 2004
    ..Iron transport assays using a buffer system that allows us to very tightly control the amount of ferrous and ferric iron will allow us to distinguish between these possibilities. ..
  5. HEPHAESTIN--A COPPER PROTEIN INVOLVED IN IRON METABOLISM
    Christopher Vulpe; Fiscal Year: 2002
    ..Understanding of the basic systems of iron transport by the mammalian organism is necessary to understand the etiology of iron deficiency anemia and iron overload in humans and devise effective therapies. ..
  6. MOLECULAR APPROACHES TO BASOLATERAL GI IRON TRANSPORT
    Christopher Vulpe; Fiscal Year: 2003
    ....
  7. Hephaestin: A Copper Protein Involved in Iron Metabolism
    Christopher Vulpe; Fiscal Year: 2003
    ..Iron transport assays using a buffer system that allows us to very tightly control the amount of ferrous and ferric iron will allow us to distinguish between these possibilities. ..
  8. MOLECULAR APPROACHES TO BASOLATERAL GI IRON TRANSPORT
    Christopher Vulpe; Fiscal Year: 2002
    ....
  9. MOLECULAR APPROACHES TO BASOLATERAL GI IRON TRANSPORT
    Christopher Vulpe; Fiscal Year: 2001
    ....
  10. HEPHAESTIN--A COPPER PROTEIN INVOLVED IN IRON METABOLISM
    Christopher Vulpe; Fiscal Year: 2001
    ..Understanding of the basic systems of iron transport by the mammalian organism is necessary to understand the etiology of iron deficiency anemia and iron overload in humans and devise effective therapies. ..
  11. HEPHAESTIN--A COPPER PROTEIN INVOLVED IN IRON METABOLISM
    Christopher Vulpe; Fiscal Year: 2000
    ..Understanding of the basic systems of iron transport by the mammalian organism is necessary to understand the etiology of iron deficiency anemia and iron overload in humans and devise effective therapies. ..
  12. MOLECULAR APPROACHES TO BASOLATERAL GI IRON TRANSPORT
    Christopher Vulpe; Fiscal Year: 2000
    ....
  13. Hephaestin: A Copper Protein Involved in Iron Metabolism
    Christopher Vulpe; Fiscal Year: 2006
    ..Iron transport assays using a buffer system that allows us to very tightly control the amount of ferrous and ferric iron will allow us to distinguish between these possibilities. ..