STEPHEN RANDAL VOSS

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. ncbi request reprint Evolutionary genetics of metamorphic failure using wild-caught vs. laboratory axolotls (Ambystoma mexicanum)
    S R Voss
    Department of Biology, Colorado State University, Fort Collins, CO 80523, USA
    Mol Ecol 9:1401-7. 2000
  2. pmc Conserved vertebrate chromosome segments in the large salamander genome
    S R Voss
    Department of Biology, Colorado State University, Fort Collins, CO 80523, USA
    Genetics 158:735-46. 2001
  3. pmc Variation in salamander tail regeneration is associated with genetic factors that determine tail morphology
    Gareth J Voss
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, Kentucky, United States of America
    PLoS ONE 8:e67274. 2013
  4. pmc Salamander Hox clusters contain repetitive DNA and expanded non-coding regions: a typical Hox structure for non-mammalian tetrapod vertebrates?
    STEPHEN RANDAL VOSS
    Department of Biology, University of Kentucky, Lexington, KY 40506, USA
    Hum Genomics 7:9. 2013
  5. pmc Thyroid hormone responsive QTL and the evolution of paedomorphic salamanders
    S R Voss
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    Heredity (Edinb) 109:293-8. 2012
  6. pmc Revisiting the relationship between regenerative ability and aging
    Ashley W Seifert
    Department of Biology, University of Kentucky, Lexington, KY 40506, USA
    BMC Biol 11:2. 2013
  7. pmc Gene order data from a model amphibian (Ambystoma): new perspectives on vertebrate genome structure and evolution
    Jeramiah J Smith
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    BMC Genomics 7:219. 2006
  8. pmc Sal-Site: integrating new and existing ambystomatid salamander research and informational resources
    Jeramiah J Smith
    Department of Biology, Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    BMC Genomics 6:181. 2005
  9. pmc From biomedicine to natural history research: EST resources for ambystomatid salamanders
    Srikrishna Putta
    Department of Biology, University of Kentucky, Lexington, KY 40506, USA
    BMC Genomics 5:54. 2004
  10. pmc Effect of thyroid hormone concentration on the transcriptional response underlying induced metamorphosis in the Mexican axolotl (Ambystoma)
    Robert B Page
    Department of Biology, University of Kentucky, Lexington, Kentucky 40506 USA
    BMC Genomics 9:78. 2008

Research Grants

  1. GENOME RESOURCES FOR MODEL AMPHIBIANS
    STEPHEN RANDAL VOSS; Fiscal Year: 2010
  2. GENOME RESOURCES FOR MODEL AMPHIBIANS
    Stephen Voss; Fiscal Year: 2006
  3. GENOME RESOURCES FOR MODEL AMPHIBIANS
    Stephen Voss; Fiscal Year: 2009

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Evolutionary genetics of metamorphic failure using wild-caught vs. laboratory axolotls (Ambystoma mexicanum)
    S R Voss
    Department of Biology, Colorado State University, Fort Collins, CO 80523, USA
    Mol Ecol 9:1401-7. 2000
    ..tigrinum tigrinum) at loci that contribute to metamorphic failure. This result suggests a role for more than one mutation and possibly artificial selection in the evolution of the major gene effect in the laboratory Mexican axolotl...
  2. pmc Conserved vertebrate chromosome segments in the large salamander genome
    S R Voss
    Department of Biology, Colorado State University, Fort Collins, CO 80523, USA
    Genetics 158:735-46. 2001
    ..Thus, comparative gene mapping appears to be an efficient strategy for identifying orthologous loci between ambystomatid salamanders and genomically well-characterized vertebrate model organisms...
  3. pmc Variation in salamander tail regeneration is associated with genetic factors that determine tail morphology
    Gareth J Voss
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, Kentucky, United States of America
    PLoS ONE 8:e67274. 2013
    ....
  4. pmc Salamander Hox clusters contain repetitive DNA and expanded non-coding regions: a typical Hox structure for non-mammalian tetrapod vertebrates?
    STEPHEN RANDAL VOSS
    Department of Biology, University of Kentucky, Lexington, KY 40506, USA
    Hum Genomics 7:9. 2013
    ..Our results suggest that Hox cluster expansion and transposon accumulation are common features of non-mammalian tetrapod vertebrates...
  5. pmc Thyroid hormone responsive QTL and the evolution of paedomorphic salamanders
    S R Voss
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    Heredity (Edinb) 109:293-8. 2012
    ..Our study demonstrates a likely pathway for the evolution of novel paedomorphic species from metamorphic ancestors via selection of TH-response alleles that delay metamorphic timing and increase adult body size...
  6. pmc Revisiting the relationship between regenerative ability and aging
    Ashley W Seifert
    Department of Biology, University of Kentucky, Lexington, KY 40506, USA
    BMC Biol 11:2. 2013
    ..See research article: http://www.biomedcentral.com/1741-7007/10/103...
  7. pmc Gene order data from a model amphibian (Ambystoma): new perspectives on vertebrate genome structure and evolution
    Jeramiah J Smith
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    BMC Genomics 7:219. 2006
    ....
  8. pmc Sal-Site: integrating new and existing ambystomatid salamander research and informational resources
    Jeramiah J Smith
    Department of Biology, Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    BMC Genomics 6:181. 2005
    ..Sal-Site is accessible at http://www.ambystoma.org...
  9. pmc From biomedicine to natural history research: EST resources for ambystomatid salamanders
    Srikrishna Putta
    Department of Biology, University of Kentucky, Lexington, KY 40506, USA
    BMC Genomics 5:54. 2004
    ..We developed ESTs for Mexican axolotl (Ambystoma mexicanum) and Eastern tiger salamander (A. tigrinum tigrinum), species with deep and diverse research histories...
  10. pmc Effect of thyroid hormone concentration on the transcriptional response underlying induced metamorphosis in the Mexican axolotl (Ambystoma)
    Robert B Page
    Department of Biology, University of Kentucky, Lexington, Kentucky 40506 USA
    BMC Genomics 9:78. 2008
    ..We induced metamorphosis in juvenile Mexican axolotls (Ambystoma mexicanum) using 5 and 50 nM T4, collected epidermal tissue from the head at four time points (Days 0, 2, 12, 28), and used microarray analysis to quantify mRNA abundances...
  11. pmc Transcriptional response of Mexican axolotls to Ambystoma tigrinum virus (ATV) infection
    Jennifer D Cotter
    School of Biological Sciences, Washington State University, Pullman, WA 99164 4236, USA
    BMC Genomics 9:493. 2008
    ..We used a custom microarray gene chip to characterize gene expression responses of axolotls (Ambystoma mexicanum) to an emerging viral pathogen, Ambystoma tigrinum virus (ATV)...
  12. pmc Genic regions of a large salamander genome contain long introns and novel genes
    Jeramiah J Smith
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    BMC Genomics 10:19. 2009
    ..Sixteen BAC clones from the Mexican axolotl (Ambystoma mexicanum: c-value = 32 x 10(9) bp) were isolated and sequenced to characterize the structure of genic regions...
  13. pmc Rapid fixation of non-native alleles revealed by genome-wide SNP analysis of hybrid tiger salamanders
    Benjamin M Fitzpatrick
    Ecology and Evolutionary Biology, University of Tennessee, Knoxville, TN 37996, USA
    BMC Evol Biol 9:176. 2009
    ..To assess variation of admixture dynamics, we scored a large panel of markers in five wild hybrid populations formed when Barred Tiger Salamanders were introduced into the range of California Tiger Salamanders...
  14. pmc Microarray analysis of a salamander hopeful monster reveals transcriptional signatures of paedomorphic brain development
    Robert B Page
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    BMC Evol Biol 10:199. 2010
    ..The basis of paedomorphic development was investigated by comparing temporal patterns of gene transcription between axolotl and tiger salamander larvae (Ambystoma tigrinum tigrinum) that typically undergo a metamorphosis...
  15. pmc Proteomic analysis of blastema formation in regenerating axolotl limbs
    Nandini Rao
    Department of Biology and Center for Regenerative Biology and Medicine, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA
    BMC Biol 7:83. 2009
    ....
  16. pmc Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration
    James R Monaghan
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    BMC Biol 7:1. 2009
    ..Innervated (NR) and denervated (DL) forelimbs of Mexican axolotls were amputated and transcripts were sampled after 0, 5, and 14 days of regeneration...
  17. pmc Evolution of salamander life cycles: a major-effect quantitative trait locus contributes to discrete and continuous variation for metamorphic timing
    S R Voss
    Department of Biology, University of Kentucky, Lexington, 40506, USA
    Genetics 170:275-81. 2005
    ..We suggest that the evolution of paedomorphosis is associated with genetic changes that delay metamorphic timing in biphasic life cycles...
  18. pmc Origin of amphibian and avian chromosomes by fission, fusion, and retention of ancestral chromosomes
    Stephen R Voss
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, Kentucky 40506, USA
    Genome Res 21:1306-12. 2011
    ..Overall, the results demonstrate the value of data from diverse, amphibian genomes in studies of vertebrate genome evolution...
  19. ncbi request reprint Candidate gene analysis of metamorphic timing in ambystomatid salamanders
    S R Voss
    Department of Biology, University of Kentucky, Lexington, KY 40506, USA
    Mol Ecol 12:1217-23. 2003
    ..The approach is thus of particular value in ecological studies where target genes have been identified but the study organism is not one of the few well-characterized model systems that dominate genetic research...
  20. pmc A comprehensive expressed sequence tag linkage map for tiger salamander and Mexican axolotl: enabling gene mapping and comparative genomics in Ambystoma
    J J Smith
    Department of Biology, University of Kentucky, Lexington, Kentucky 40506, USA
    Genetics 171:1161-71. 2005
    ..This new collection of EST-based PCR markers will better enable the Ambystoma system by facilitating development of new molecular probes, and the linkage map will allow comparative studies of this important vertebrate group...
  21. ncbi request reprint Candidate gene analysis of thyroid hormone receptors in metamorphosing vs. nonmetamorphosing salamanders
    S R Voss
    Department of Biology, Colorado State University, Ft Collins, CO 80523, USA
    Heredity (Edinb) 85:107-14. 2000
    ..These data do not implicate TRs as candidate loci involved in the current maintenance or past evolution of alternate life cycle modes in members of the tiger salamander complex...
  22. pmc Amphibian sex determination: segregation and linkage analysis using members of the tiger salamander species complex (Ambystoma mexicanum and A. t. tigrinum)
    J J Smith
    Department of Biology and Spinal Cord, Brian Injury Research Center, University of Kentucky, Lexington, KY, USA
    Heredity (Edinb) 102:542-8. 2009
    ..Localization of ambysex sets the stage for gene identification and provides important tools for studying the effect of sex in laboratory and natural populations of this model amphibian system...

Research Grants12

  1. GENOME RESOURCES FOR MODEL AMPHIBIANS
    STEPHEN RANDAL VOSS; Fiscal Year: 2010
    ..With respect to longer-term goals, the proposed project will spur development of additional resources that will facilitate identification of salamander genes of biomedical significance. ..
  2. GENOME RESOURCES FOR MODEL AMPHIBIANS
    Stephen Voss; Fiscal Year: 2006
    ..With respect to longer term goals, the proposed project will spur development of additional resources that will facilitate identification of salamander genes of biomedical significance. ..
  3. GENOME RESOURCES FOR MODEL AMPHIBIANS
    Stephen Voss; Fiscal Year: 2009
    ..With respect to longer-term goals, the proposed project will spur development of additional resources that will facilitate identification of salamander genes of biomedical significance. ..