Wanpen Vongpatanasin

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi request reprint Cardiovascular morbidity and mortality in high-risk populations: epidemiology and opportunities for risk reduction
    Wanpen Vongpatanasin
    Hypertension Division and the Donald W Reynolds Cardiovascular Clinical Research Center, Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 8586, USA
    J Clin Hypertens (Greenwich) 9:11-5. 2007
  2. ncbi request reprint Management of hypertension in patients with coronary artery disease
    Wanpen Vongpatanasin
    University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, U9 400, Dallas, TX 75390, USA
    Curr Hypertens Rep 10:349-54. 2008
  3. doi request reprint Autonomic regulation of blood pressure in menopause
    Wanpen Vongpatanasin
    Department of Internal Medicine, Hypertension Division, University of Texas Southwestern Medical Center, Dallas, TX 75390 8586, USA
    Semin Reprod Med 27:338-45. 2009
  4. pmc Functional sympatholysis is impaired in hypertensive humans
    Wanpen Vongpatanasin
    Hypertension Section, Cardiology Division, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, U9 400, Dallas, TX 75390 8586, USA
    J Physiol 589:1209-20. 2011
  5. doi request reprint Central sympatholytic drugs
    Wanpen Vongpatanasin
    Hypertension Section, University of Texas Southwestern Medical Center, Dallas, TX, USA
    J Clin Hypertens (Greenwich) 13:658-61. 2011
  6. ncbi request reprint Effects of cocaine on heart rate variability in healthy subjects
    Wanpen Vongpatanasin
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA
    Am J Cardiol 93:385-8. 2004
  7. ncbi request reprint Differential effects of oral versus transdermal estrogen replacement therapy on C-reactive protein in postmenopausal women
    Wanpen Vongpatanasin
    Donald W Reynolds Cardiovascular Clinical Research Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75390, USA
    J Am Coll Cardiol 41:1358-63. 2003
  8. pmc Differential effects of nebivolol versus metoprolol on functional sympatholysis in hypertensive humans
    Angela Price
    Hypertension Section, Cardiology Division, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, U9 400, Dallas, TX 75390 8586, USA
    Hypertension 61:1263-9. 2013
  9. pmc Probing the mechanisms of intradialytic hypertension: a pilot study targeting endothelial cell dysfunction
    Jula K Inrig
    University of Texas Southwestern Medical Center, Dallas, Texas 75390 8523, USA
    Clin J Am Soc Nephrol 7:1300-9. 2012
  10. ncbi request reprint C-reactive protein downregulates endothelial NO synthase and attenuates reendothelialization in vivo in mice
    Randall Schwartz
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Circ Res 100:1452-9. 2007

Research Grants

  1. POSTMENOPAUSAL HORMONAL REPLACEMENT THERAPY
    Wanpen Vongpatanasin; Fiscal Year: 2002
  2. POSTMENOPAUSAL HORMONAL REPLACEMENT THERAPY
    Wanpen Vongpatanasin; Fiscal Year: 2003
  3. POSTMENOPAUSAL HORMONAL REPLACEMENT THERAPY
    Wanpen Vongpatanasin; Fiscal Year: 2004
  4. POSTMENOPAUSAL HORMONAL REPLACEMENT THERAPY
    Wanpen Vongpatanasin; Fiscal Year: 2005
  5. Neural Mechanism of Thiazide-Induced Insulin Resistance
    Wanpen Vongpatanasin; Fiscal Year: 2006
  6. POSTMENOPAUSAL HORMONAL REPLACEMENT THERAPY
    Wanpen Vongpatanasin; Fiscal Year: 2006
  7. Neural Mechanism of Thiazide-Induced Insulin Resistance
    Wanpen Vongpatanasin; Fiscal Year: 2005
  8. Neural Mechanism of Thiazide-Induced Insulin Resistance
    Wanpen Vongpatanasin; Fiscal Year: 2007

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Cardiovascular morbidity and mortality in high-risk populations: epidemiology and opportunities for risk reduction
    Wanpen Vongpatanasin
    Hypertension Division and the Donald W Reynolds Cardiovascular Clinical Research Center, Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 8586, USA
    J Clin Hypertens (Greenwich) 9:11-5. 2007
    ....
  2. ncbi request reprint Management of hypertension in patients with coronary artery disease
    Wanpen Vongpatanasin
    University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, U9 400, Dallas, TX 75390, USA
    Curr Hypertens Rep 10:349-54. 2008
    ..Given the enormous gap between current BP levels in patients with CAD and the new target BP goals, multiple drug therapy is essential to achieve BP control and improve cardiovascular outcomes...
  3. doi request reprint Autonomic regulation of blood pressure in menopause
    Wanpen Vongpatanasin
    Department of Internal Medicine, Hypertension Division, University of Texas Southwestern Medical Center, Dallas, TX 75390 8586, USA
    Semin Reprod Med 27:338-45. 2009
    ..The alteration in central autonomic regulation coupled with enhanced vascular adrenergic sensitivity may be responsible for elevation in resting BP and exaggerated pressor responses to exercise and mental stress in postmenopausal women...
  4. pmc Functional sympatholysis is impaired in hypertensive humans
    Wanpen Vongpatanasin
    Hypertension Section, Cardiology Division, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, U9 400, Dallas, TX 75390 8586, USA
    J Physiol 589:1209-20. 2011
    ..These data provide the first evidence that functional sympatholysis is impaired in hypertensive humans by a mechanism that appears to involve an angiotensin-dependent increase in sympathetic vasoconstriction in the exercising muscles...
  5. doi request reprint Central sympatholytic drugs
    Wanpen Vongpatanasin
    Hypertension Section, University of Texas Southwestern Medical Center, Dallas, TX, USA
    J Clin Hypertens (Greenwich) 13:658-61. 2011
    ..Therefore, their use on a "PRN" basis for treatment of blood pressure surge in the absence of symptoms or acute target complications should also be avoided...
  6. ncbi request reprint Effects of cocaine on heart rate variability in healthy subjects
    Wanpen Vongpatanasin
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA
    Am J Cardiol 93:385-8. 2004
    ..However, the results of our autonomic blocking studies indicated the opposite, suggesting a major influence of cardiac sympathetic drive on the high-frequency power of heart rate variability...
  7. ncbi request reprint Differential effects of oral versus transdermal estrogen replacement therapy on C-reactive protein in postmenopausal women
    Wanpen Vongpatanasin
    Donald W Reynolds Cardiovascular Clinical Research Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75390, USA
    J Am Coll Cardiol 41:1358-63. 2003
    ..We investigated whether the route of estrogen replacement therapy (ET) is the major determinant of C-reactive protein (CRP) in postmenopausal women...
  8. pmc Differential effects of nebivolol versus metoprolol on functional sympatholysis in hypertensive humans
    Angela Price
    Hypertension Section, Cardiology Division, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, U9 400, Dallas, TX 75390 8586, USA
    Hypertension 61:1263-9. 2013
    ..Clinical Trial Registration- URL: http://www.clinicaltrials.gov. Unique identifier: NCT01502787...
  9. pmc Probing the mechanisms of intradialytic hypertension: a pilot study targeting endothelial cell dysfunction
    Jula K Inrig
    University of Texas Southwestern Medical Center, Dallas, Texas 75390 8523, USA
    Clin J Am Soc Nephrol 7:1300-9. 2012
    ..This study hypothesized that carvedilol would improve endothelial cell function and reduce the occurrence of intradialytic hypertension...
  10. ncbi request reprint C-reactive protein downregulates endothelial NO synthase and attenuates reendothelialization in vivo in mice
    Randall Schwartz
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Circ Res 100:1452-9. 2007
    ..Thus, CRP downregulates eNOS and attenuates reendothelialization in vivo in mice, and this action of CRP on eNOS is mediated at the level of gene transcription...
  11. pmc Spironolactone prevents chlorthalidone-induced sympathetic activation and insulin resistance in hypertensive patients
    Prafull Raheja
    Hypertension Section, Cardiology Division, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 8586, USA
    Hypertension 60:319-25. 2012
    ....
  12. pmc Elderly blacks have a blunted sympathetic neural responsiveness but greater pressor response to orthostasis than elderly whites
    Yoshiyuki Okada
    Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, TX, USA
    Hypertension 60:842-8. 2012
    ....
  13. pmc Differential effects of chlorthalidone versus spironolactone on muscle sympathetic nerve activity in hypertensive patients
    Dileep V Menon
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8586, USA
    J Clin Endocrinol Metab 94:1361-6. 2009
    ....
  14. pmc Augmented sympathetic vasoconstriction in exercising forearms of postmenopausal women is reversed by oestrogen therapy
    Paul J Fadel
    Hypertension Division, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 8586, USA
    J Physiol 561:893-901. 2004
    ..The effect of short-term unopposed oestrogen replacement to correct this impairment implicates a role for oestrogen in the sympathetic neural control of muscle haemodynamics during exercise...
  15. pmc Reversible sympathetic overactivity in hypertensive patients with primary aldosteronism
    Andrew C Kontak
    Cardiology Division, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8586, USA
    J Clin Endocrinol Metab 95:4756-61. 2010
    ..Aldosterone has been shown to exert a central sympathoexcitatory action in multiple animal models, but evidence in humans is still lacking...
  16. pmc Adiposity-independent sympathetic activity in black men
    Aamer Abbas
    Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, U9 400, Dallas, TX 75390 8586, USA
    J Appl Physiol (1985) 108:1613-8. 2010
    ..05). In conclusion, these new data from this prospective study provide strong support for a major adiposity-independent sympathetic activity in black men and adiposity-related sympathetic activity in black women...
  17. pmc Reflex sympathetic activation during static exercise is severely impaired in patients with myophosphorylase deficiency
    Paul J Fadel
    Department of Internal Medicine, Division of Hypertension, University of Texas Southwestern Medical Center, Dallas, USA
    J Physiol 548:983-93. 2003
    ..Together these data indicate that appropriate activation of glycogenolytic pathways is obligatory for normal metaboreflex-mediated sympathoexcitation during static exercise in humans...
  18. ncbi request reprint Central sympatholysis as a novel countermeasure for cocaine-induced sympathetic activation and vasoconstriction in humans
    Dileep V Menon
    Hypertension Division and the Donald W Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8586, USA
    J Am Coll Cardiol 50:626-33. 2007
    ..The aim of this study was to determine whether cocaine's sympathomimetic actions can be reversed by a potent centrally acting alpha2 adrenergic receptor (AR) agonist (dexmedetomidine)...
  19. ncbi request reprint Mechanism of the blood pressure--raising effect of cocaine in humans
    Meryem Tuncel
    Department of Internal Medicine, Hypertension Division, and Donald W Reynolds Cardiovascular Clinical Research Center, UT Southwestern Medical Center, Dallas, TX 75390 8586, USA
    Circulation 105:1054-9. 2002
    ..We asked (a) whether cocaine can inhibit NE reuptake in the human peripheral circulation and (b) whether the NE-mediated peripheral vasoconstriction is the main mechanism mediating blood pressure-raising effect of cocaine...
  20. ncbi request reprint Contrasting effects of oral versus transdermal estrogen on serum amyloid A (SAA) and high-density lipoprotein-SAA in postmenopausal women
    Aamer Abbas
    Department of Internal Medicine, University of Texas, Dallas, USA
    Arterioscler Thromb Vasc Biol 24:e164-7. 2004
    ....
  21. doi request reprint Dexmedetomidine as a novel countermeasure for cocaine-induced central sympathoexcitation in cocaine-addicted humans
    Andrew C Kontak
    Hypertension Section, Cardiology Division, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Hypertension 61:388-94. 2013
    ....
  22. pmc Relationship between sympathetic baroreflex sensitivity and arterial stiffness in elderly men and women
    Yoshiyuki Okada
    Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital, Dallas, TX 75231, USA
    Hypertension 59:98-104. 2012
    ..The lower sympathetic baroreflex sensitivity in elderly women may predispose them to an increased prevalence of hypertension...
  23. ncbi request reprint Measurement of 18-hydroxycorticosterone during adrenal vein sampling for primary aldosteronism
    Richard J Auchus
    Division of Endocrinology and Metabolism, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390 8857, USA
    J Clin Endocrinol Metab 92:2648-51. 2007
    ....
  24. pmc C-reactive protein causes insulin resistance in mice through Fcγ receptor IIB-mediated inhibition of skeletal muscle glucose delivery
    Keiji Tanigaki
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Diabetes 62:721-31. 2013
    ..Thus, CRP causes insulin resistance in mice through FcγRIIB-mediated inhibition of skeletal muscle glucose delivery...
  25. ncbi request reprint C-reactive protein causes downregulation of vascular angiotensin subtype 2 receptors and systolic hypertension in mice
    Wanpen Vongpatanasin
    Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    Circulation 115:1020-8. 2007
    ..Chronic elevations in circulating C-reactive protein (CRP) are associated with a greater risk of hypertension. Whether elevations in CRP cause hypertension is unknown...
  26. ncbi request reprint Estrogen and hypertension
    Muhammad S Ashraf
    Divisions of Hypertension, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, J4 134, Dallas, TX 75390 8586, USA
    Curr Hypertens Rep 8:368-76. 2006
    ..To date, transdermal delivery of estrogen, which avoids the first-pass hepatic metabolism of estradiol, appears to have a small BP-lowering effect in postmenopausal women and may be a safer alternative in hypertensive women...
  27. pmc Intradialytic hypertension and its association with endothelial cell dysfunction
    Jula K Inrig
    UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8523, USA
    Clin J Am Soc Nephrol 6:2016-24. 2011
    ..We hypothesized that intradialytic hypertension is associated in vivo with endothelial cell dysfunction, a novel predictor of adverse cardiovascular outcomes...
  28. ncbi request reprint Mechanism of cocaine-induced hyperthermia in humans
    Craig G Crandall
    Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, 7232 Greenville Avenue, Dallas, TX 75231, USA
    Ann Intern Med 136:785-91. 2002
    ..However, because cocaine-induced hyperthermia occurs primarily in hot weather, it is hypothesized that cocaine also impairs thermoregulatory adjustments that mediate heat dissipation...
  29. pmc Risk of methylphenidate-induced prehypertension in normotensive adult smokers with attention deficit hyperactivity disorder
    Arthur N Westover
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 8828, USA
    J Clin Hypertens (Greenwich) 15:124-32. 2013
    ..The authors demonstrated an augmented OROS-MPH-induced BP elevation and risk of prehypertension in adults with baseline normal BP. Significantly increased BP was not observed in adults with baseline prehypertension...
  30. ncbi request reprint Do allelic variants in alpha2A and alpha2C adrenergic receptors predispose to hypertension in blacks?
    Jia Ling Li
    Division of Hypertension, Department of Internal Medicine, Donald W Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, USA
    Hypertension 47:1140-6. 2006
    ..Both the DraI restriction fragment length polymorphism in ADRA2A and the ADRA2C (Del 322 to 325) can be excluded as major candidate alleles for hypertension in blacks...
  31. pmc Neural and nonneural mechanisms for sex differences in elderly hypertension: can exercise training help?
    Qi Fu
    Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, Dallas, TX 75231, USA
    Hypertension 52:787-94. 2008
  32. ncbi request reprint Resistant hypertension: a review of diagnosis and management
    Wanpen Vongpatanasin
    Hypertension Section, Cardiology Division, University of Texas Southwestern Medical Center, Dallas
    JAMA 311:2216-24. 2014
    ..Treating these disorders can significantly improve blood pressure beyond medical therapy alone. The role of device therapy for treating the typical patient with resistant hypertension remains unclear. ..
  33. ncbi request reprint Race and gender differences in C-reactive protein levels
    Amit Khera
    Donald W Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9047, USA
    J Am Coll Cardiol 46:464-9. 2005
    ..This study sought to determine whether there are race and gender differences in the distribution of C-reactive protein (CRP) levels...
  34. ncbi request reprint Myocardial triglycerides and systolic function in humans: in vivo evaluation by localized proton spectroscopy and cardiac imaging
    Lidia S Szczepaniak
    Department of Internal Medicine, University of Texas, Southwestern Medical Center at Dallas, USA
    Magn Reson Med 49:417-23. 2003
    ..Increased myocardial triglyceride content was accompanied by elevated LV mass and suppressed septal wall thickening as measured by cardiac imaging...
  35. ncbi request reprint Primary hyperaldosteronism: effect of adrenal vein sampling on surgical outcome
    Fiemu E Nwariaku
    Department of Surgery, University of Texas Southwestern Medical Center, Dallas 75390 9156, USA
    Arch Surg 141:497-502; discussion 502-3. 2006
    ..Adrenal vein sampling is superior to computed tomography for subtype differentiation of primary hyperaldosteronism...
  36. ncbi request reprint Blunted circadian variation in autonomic regulation of sinus node function in veterans with Gulf War syndrome
    Robert W Haley
    Divisions of Epidemiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8874, USA
    Am J Med 117:469-78. 2004
    ..To test the hypothesis that subtle abnormalities of the autonomic nervous system underlie the chronic symptoms reported by many Gulf War veterans, such as chronic diarrhea, dizziness, fatigue, and sexual dysfunction...
  37. ncbi request reprint Management of neurogenic orthostatic hypotension
    Debbie Arbique
    UT Southwestern Medical Center at Dallas, Internal Medicine, Cardiology Division Hypertension Section, Dallas, TX
    J Am Med Dir Assoc 15:234-9. 2014
    ....
  38. ncbi request reprint High-density lipoprotein promotes endothelial cell migration and reendothelialization via scavenger receptor-B type I
    Divya Seetharam
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Circ Res 98:63-72. 2006
    ..Furthermore, reendothelialization is impaired in SR-BI(-/-) mice. Thus, HDL stimulates endothelial cell migration via SR-BI-initiated signaling, and these mechanisms promote endothelial monolayer integrity in vivo...
  39. ncbi request reprint Basis for the cardiac-related rhythm in muscle sympathetic nerve activity of humans
    Susan M Barman
    Department of Pharmacology and Toxicology, Michigan State University, East Lansing 48824, USA
    Am J Physiol Heart Circ Physiol 284:H584-97. 2003
    ..These results support the view that the cardiac-related rhythm in MSNA reflects forcing of a nonlinear oscillator rather than periodic inhibition of unstructured, random activity...
  40. ncbi request reprint Fractal properties of human muscle sympathetic nerve activity
    Paul J Fadel
    Dept of Pharmacology and Toxicology, Michigan State Univ, East Lansing, MI 48824, USA
    Am J Physiol Heart Circ Physiol 286:H1076-87. 2004
    ..Whether sympathetic outflow to the heart also is fractal and contributes to the fractal component of heart rate variability remains an open question...

Research Grants9

  1. POSTMENOPAUSAL HORMONAL REPLACEMENT THERAPY
    Wanpen Vongpatanasin; Fiscal Year: 2002
    ..The long-term goal of her work would be the discovery the most effective estrogen preparation that can prevent or treat hypertension in women after menopause. ..
  2. POSTMENOPAUSAL HORMONAL REPLACEMENT THERAPY
    Wanpen Vongpatanasin; Fiscal Year: 2003
    ..The long-term goal of her work would be the discovery the most effective estrogen preparation that can prevent or treat hypertension in women after menopause. ..
  3. POSTMENOPAUSAL HORMONAL REPLACEMENT THERAPY
    Wanpen Vongpatanasin; Fiscal Year: 2004
    ..The long-term goal of her work would be the discovery the most effective estrogen preparation that can prevent or treat hypertension in women after menopause. ..
  4. POSTMENOPAUSAL HORMONAL REPLACEMENT THERAPY
    Wanpen Vongpatanasin; Fiscal Year: 2005
    ..The long-term goal of her work would be the discovery the most effective estrogen preparation that can prevent or treat hypertension in women after menopause. ..
  5. Neural Mechanism of Thiazide-Induced Insulin Resistance
    Wanpen Vongpatanasin; Fiscal Year: 2006
    ....
  6. POSTMENOPAUSAL HORMONAL REPLACEMENT THERAPY
    Wanpen Vongpatanasin; Fiscal Year: 2006
    ..The long-term goal of her work would be the discovery the most effective estrogen preparation that can prevent or treat hypertension in women after menopause. ..
  7. Neural Mechanism of Thiazide-Induced Insulin Resistance
    Wanpen Vongpatanasin; Fiscal Year: 2005
    ....
  8. Neural Mechanism of Thiazide-Induced Insulin Resistance
    Wanpen Vongpatanasin; Fiscal Year: 2007
    ....