M A Vizzard

Summary

Affiliation: University of Vermont
Country: USA

Publications

  1. ncbi request reprint Increased expression of neuronal nitric oxide synthase in bladder afferent and spinal neurons following spinal cord injury
    M A Vizzard
    College of Medicine, University of Vermont, Department of Neurology 0540, USA
    Dev Neurosci 19:232-46. 1997
  2. ncbi request reprint Alterations in neuropeptide expression in lumbosacral bladder pathways following chronic cystitis
    M A Vizzard
    Department of Anatomy and Neurology, University of Vermont College of Medicine, E219 Given Building, Burlington, VT 05405, USA
    J Chem Neuroanat 21:125-38. 2001
  3. ncbi request reprint Increased expression of spinal cord Fos protein induced by bladder stimulation after spinal cord injury
    M A Vizzard
    University of Vermont College of Medicine, Departments of Neurology and Anatomy and Neurobiology, Burlington, Vermont 05405, USA
    Am J Physiol Regul Integr Comp Physiol 279:R295-305. 2000
  4. ncbi request reprint Up-regulation of pituitary adenylate cyclase-activating polypeptide in urinary bladder pathways after chronic cystitis
    M A Vizzard
    Department of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Comp Neurol 420:335-48. 2000
  5. ncbi request reprint Alterations in spinal cord Fos protein expression induced by bladder stimulation following cystitis
    M A Vizzard
    University of Vermont College of Medicine, Departments of Neurology and Anatomy and Neurobiology, Burlington, Vermont 05405, USA
    Am J Physiol Regul Integr Comp Physiol 278:R1027-39. 2000
  6. ncbi request reprint Developmental expression of urinary bladder neurotrophic factor mRNA and protein in the neonatal rat
    M A Vizzard
    University of Vermont College of Medicine, Departments of Neurology and Anatomy and Neurobiology, E219 Given Building, Burlington, VT 05405, USA
    Brain Res Dev Brain Res 119:217-24. 2000
  7. ncbi request reprint Transneuronal labeling of neurons in the adult rat central nervous system following inoculation of pseudorabies virus into the colon
    M A Vizzard
    University of Vermont, College of Medicine, Department of Neurology, Burlington 05405, USA
    Cell Tissue Res 299:9-26. 2000
  8. ncbi request reprint Alterations in growth-associated protein (GAP-43) expression in lower urinary tract pathways following chronic spinal cord injury
    M A Vizzard
    Department of Neurology and Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington 05405, USA
    Somatosens Mot Res 16:369-81. 1999
  9. ncbi request reprint Increased expression of growth-associated protein (GAP-43) in lower urinary tract pathways following cyclophosphamide (CYP)-induced cystitis
    M A Vizzard
    Departments of Neurology and Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Brain Res 844:174-87. 1999
  10. ncbi request reprint Changes in galanin immunoreactivity in rat lumbosacral spinal cord and dorsal root ganglia after spinal cord injury
    K Zvarova
    Department of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Comp Neurol 475:590-603. 2004

Collaborators

  • Peter Zvara
  • L-Y Qiao
  • L Birder
  • RICHARD GALBRAITH
  • W C de Groat
  • E Murray
  • G Apodaca
  • DIANE JAWORSKI
  • R L Parsons
  • Shelley J Allen
  • Beatrice M Girard
  • Susan E Malley
  • Victor May
  • Mary Beth Klinger
  • Karen M Braas
  • Simon Studeny
  • Bopaiah P Cheppudira
  • Abbey Dattilio
  • Katarina Zvarova
  • Jennifer LaBerge
  • K Zvarova
  • Kimberly A Corrow
  • John D Tompkins
  • Lauren Arms
  • K A Corrow
  • Kristin C Schutz
  • Beatrice Girard
  • James A Waschek
  • H Tan
  • Ruhin Yuridullah
  • Muyao Li
  • Gerald M Herrera
  • J Dana Dunleavy
  • Vivian Y Hu
  • V Y Hu
  • T S Lishnak
  • Susan Meyers
  • Amanda Wolf-Johnston
  • Kimberly Corrow
  • Elena M Balestreire
  • G M Mawe
  • Bernhard Nausch
  • Mark T Nelson
  • Jan Kliment
  • R Paul Stroemer
  • David Dawbarn
  • Travis L Redman
  • Ali Torabi
  • A Dattilio
  • S Malley
  • J B Folsom

Detail Information

Publications50

  1. ncbi request reprint Increased expression of neuronal nitric oxide synthase in bladder afferent and spinal neurons following spinal cord injury
    M A Vizzard
    College of Medicine, University of Vermont, Department of Neurology 0540, USA
    Dev Neurosci 19:232-46. 1997
    ..Changes in the neurochemical properties of these neurons after SCI may be mediated by pathological changes in the target organ (i.e., urinary bladder) and/or spinal cord...
  2. ncbi request reprint Alterations in neuropeptide expression in lumbosacral bladder pathways following chronic cystitis
    M A Vizzard
    Department of Anatomy and Neurology, University of Vermont College of Medicine, E219 Given Building, Burlington, VT 05405, USA
    J Chem Neuroanat 21:125-38. 2001
    ..Changes in CGRP or SP expression following cystitis may contribute to the altered visceral sensation (allodynia) and/or urinary bladder hyperreflexia in the clinical syndrome, interstitial cystitis...
  3. ncbi request reprint Increased expression of spinal cord Fos protein induced by bladder stimulation after spinal cord injury
    M A Vizzard
    University of Vermont College of Medicine, Departments of Neurology and Anatomy and Neurobiology, Burlington, Vermont 05405, USA
    Am J Physiol Regul Integr Comp Physiol 279:R295-305. 2000
    ..These data suggest that SCI can reveal an altered Fos expression pattern in response to a nonnoxious bladder stimulus that is partially mediated by capsaicin-sensitive bladder afferents...
  4. ncbi request reprint Up-regulation of pituitary adenylate cyclase-activating polypeptide in urinary bladder pathways after chronic cystitis
    M A Vizzard
    Department of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Comp Neurol 420:335-48. 2000
    ..Changes in PACAP expression after cystitis may play a role in altered visceral sensation (allodynia) and/or urinary bladder hyperreflexia in the clinical syndrome, interstitial cystitis...
  5. ncbi request reprint Alterations in spinal cord Fos protein expression induced by bladder stimulation following cystitis
    M A Vizzard
    University of Vermont College of Medicine, Departments of Neurology and Anatomy and Neurobiology, Burlington, Vermont 05405, USA
    Am J Physiol Regul Integr Comp Physiol 278:R1027-39. 2000
    ..These data suggest that chronic cystitis can reveal a nociceptive Fos expression pattern in the spinal cord in response to a non-noxious bladder stimulus that is partially mediated by capasaicin-sensitive bladder afferents...
  6. ncbi request reprint Developmental expression of urinary bladder neurotrophic factor mRNA and protein in the neonatal rat
    M A Vizzard
    University of Vermont College of Medicine, Departments of Neurology and Anatomy and Neurobiology, E219 Given Building, Burlington, VT 05405, USA
    Brain Res Dev Brain Res 119:217-24. 2000
    ..Relatively high expression of NT-3 and NT-4 protein in the adult urinary bladder suggests a potential importance of these factors in the adult lower urinary tract...
  7. ncbi request reprint Transneuronal labeling of neurons in the adult rat central nervous system following inoculation of pseudorabies virus into the colon
    M A Vizzard
    University of Vermont, College of Medicine, Department of Neurology, Burlington 05405, USA
    Cell Tissue Res 299:9-26. 2000
    ....
  8. ncbi request reprint Alterations in growth-associated protein (GAP-43) expression in lower urinary tract pathways following chronic spinal cord injury
    M A Vizzard
    Department of Neurology and Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington 05405, USA
    Somatosens Mot Res 16:369-81. 1999
    ....
  9. ncbi request reprint Increased expression of growth-associated protein (GAP-43) in lower urinary tract pathways following cyclophosphamide (CYP)-induced cystitis
    M A Vizzard
    Departments of Neurology and Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Brain Res 844:174-87. 1999
    ....
  10. ncbi request reprint Changes in galanin immunoreactivity in rat lumbosacral spinal cord and dorsal root ganglia after spinal cord injury
    K Zvarova
    Department of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Comp Neurol 475:590-603. 2004
    ..Changes in galanin expression in micturition pathways after SCI may be mediated by changing neurotrophic factor expression, particularly BDNF. These changes may contribute to urinary bladder dysfunction after SCI...
  11. pmc Phosphorylation of extracellular signal-regulated kinases in bladder afferent pathways with cyclophosphamide-induced cystitis
    K A Corrow
    Department of Neurology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Neuroscience 163:1353-62. 2009
    ..These studies suggest that activation of the ERK pathway in lumbosacral DRG may play a role in neuroplasticity in micturition reflexes with CYP-induced cystitis...
  12. ncbi request reprint Changes in galanin immunoreactivity in rat micturition reflex pathways after cyclophosphamide-induced cystitis
    K Zvarova
    Departments of Neurology and Anatomy and Neurobiology, College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Cell Tissue Res 324:213-24. 2006
    ..Galanin-IR was observed encircling DRG cells after chronic cystitis. These changes may contribute to urinary bladder dysfunction, altered sensation, and referred somatic hyperalgesia after cystitis...
  13. ncbi request reprint Changes in pituitary adenylate cyclase activating polypeptide expression in urinary bladder pathways after spinal cord injury
    Katarina Zvarova
    Department of Neurology, University of Vermont, College of Medicine, D411 Given Building, Burlington, VT 05405, USA
    Exp Neurol 192:46-59. 2005
    ..These studies demonstrate changes in PACAP expression in micturition reflex pathways after SCI that may contribute to urinary bladder dysfunction or reemergence of primitive voiding reflexes after SCI...
  14. ncbi request reprint Phosphorylation of CREB in thoracolumbar spinal neurons and dorsal root ganglia after renal artery occlusion in rat
    T S Lishnak
    Department of Neurology, College of Medicine, University of Vermont, Burlington 05405, USA
    Auton Neurosci 94:62-73. 2001
    ..In addition, expression of p-CREB-IR may be coupled to late response genes that may exert long-term changes in neuronal function after RAO...
  15. ncbi request reprint Up-regulation of phosphorylated CREB but not c-Jun in bladder afferent neurons in dorsal root ganglia after cystitis
    Li Ya Qiao
    Department of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Comp Neurol 469:262-74. 2004
    ..Colocalization of p-CREB and Trk receptor(s) showed that a subpopulation of p-CREB-IR cells expressed p-Trk with cystitis. These results suggest that up-regulation of p-CREB may be mediated by a neurotrophin/Trk signaling pathway...
  16. ncbi request reprint Cystitis-induced upregulation of tyrosine kinase (TrkA, TrkB) receptor expression and phosphorylation in rat micturition pathways
    Li Ya Qiao
    Department of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Comp Neurol 454:200-11. 2002
    ....
  17. pmc Upregulation of vascular endothelial growth factor isoform VEGF-164 and receptors (VEGFR-2, Npn-1, and Npn-2) in rats with cyclophosphamide-induced cystitis
    Bopaiah P Cheppudira
    Department of Neurology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Am J Physiol Renal Physiol 295:F826-36. 2008
    ..Functional role(s) for the VEGF-VEGF receptor system in urinary bladder inflammation remain to be determined...
  18. pmc Role for pituitary adenylate cyclase activating polypeptide in cystitis-induced plasticity of micturition reflexes
    Karen M Braas
    University of Vermont College of Medicine, Department of Anatomy and Neurobiology, Burlington, VT 05405, USA
    Am J Physiol Regul Integr Comp Physiol 290:R951-62. 2006
    ..In summary, these studies support roles for PACAP in micturition and suggest that inflammation-induced plasticity in PACAP expression in peripheral and central micturition pathways contribute to bladder dysfunction with cystitis...
  19. ncbi request reprint Expression of corticotropin-releasing factor and CRF receptors in micturition pathways after cyclophosphamide-induced cystitis
    Jennifer LaBerge
    Dept of Anatomy, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Am J Physiol Regul Integr Comp Physiol 291:R692-703. 2006
    ..CRF may contribute to urinary bladder overactivity and altered sensory processing with CYP-induced cystitis...
  20. ncbi request reprint Spinal cord injury-induced expression of TrkA, TrkB, phosphorylated CREB, and c-Jun in rat lumbosacral dorsal root ganglia
    Li Ya Qiao
    Department of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Comp Neurol 482:142-54. 2005
    ..However, CREB or c-Jun may not be downstream transcription factors in Trk-mediated signaling cascades in micturition reflex pathways after SCI but may play a role in other, nonbladder SCI-induced changes...
  21. ncbi request reprint Phosphorylation of extracellular signal-regulated kinases in urinary bladder in rats with cyclophosphamide-induced cystitis
    Kimberly A Corrow
    Department of Neurology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Am J Physiol Regul Integr Comp Physiol 293:R125-34. 2007
    ..01) increased bladder capacity in CYP-treated rats (48 h). These studies suggest that therapies targeted at pERK pathways may improve urinary bladder function in CYP-treated rats...
  22. pmc PACAP-mediated ATP release from rat urothelium and regulation of PACAP/VIP and receptor mRNA in micturition pathways after cyclophosphamide (CYP)-induced cystitis
    Beatrice M Girard
    Department of Anatomy and Neurobiology, University of Vermont, Burlington, VT 05405, USA
    J Mol Neurosci 36:310-20. 2008
    ..The current data demonstrate PACAP and PAC1 regulation in micturition pathways with inflammation and PACAP-mediated ATP release from urothelium...
  23. pmc Expression and function of CXCL12/CXCR4 in rat urinary bladder with cyclophosphamide-induced cystitis
    Lauren Arms
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    Am J Physiol Renal Physiol 298:F589-600. 2010
    ..01) increases in intercontraction interval, bladder capacity, and void volume. These results suggest a role for CXCL12/CXCR4 signaling in both normal micturition and with bladder hyperreflexia following bladder inflammation...
  24. ncbi request reprint Expression of cyclooxygenase-2 in urinary bladder in rats with cyclophosphamide-induced cystitis
    Mary Beth Klinger
    Univ of Vermont College of Medicine, Dept of Neurology, D415A Given Research Bldg, Burlington, VT 05405
    Am J Physiol Regul Integr Comp Physiol 293:R677-85. 2007
    ..COX-2-IR macrophages (CD86+) were present throughout the urinary bladder with acute and chronic CYP-induced cystitis. These studies demonstrate cellular targets in the urinary bladder where COX-2 inhibitors may act...
  25. pmc Exogenous overexpression of nerve growth factor in the urinary bladder produces bladder overactivity and altered micturition circuitry in the lumbosacral spinal cord
    Peter Zvara
    Department of Surgery, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, VT 05405, USA
    BMC Physiol 7:9. 2007
    ....
  26. doi request reprint p75NTR expression in rat urinary bladder sensory neurons and spinal cord with cyclophosphamide-induced cystitis
    Mary Beth Klinger
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Comp Neurol 507:1379-92. 2008
    ..The functional significance of p75(NTR) expression in micturition reflexes remains to be determined...
  27. ncbi request reprint Neurochemical plasticity and the role of neurotrophic factors in bladder reflex pathways after spinal cord injury
    Margaret A Vizzard
    Department of Neurology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Prog Brain Res 152:97-115. 2006
    ....
  28. ncbi request reprint Prolonged retention of the anorectic cobalt protoporphyrin in the hypothalamus and the resulting expression of Fos
    Richard A Galbraith
    Department of Medicine, University of Vermont, Burlington, Vermont 05405, USA
    Am J Physiol Regul Integr Comp Physiol 287:R465-71. 2004
    ..Thus CoPP remains in the hypothalamus for prolonged periods and activates Fos expression in the hypothalamus...
  29. pmc VIP and PACAP effects on mouse major pelvic ganglia neurons
    John D Tompkins
    Departments of Anatomy and Neurobiology, College of Medicine, University of Vermont, Burlington, VT 05405, USA
    J Mol Neurosci 42:390-6. 2010
    ..The results suggest that VIP has a role in the neural control of pelvic organ function and activation of VPAC and/or PAC1 receptors can modulate the activity of the autonomic neurons innervating pelvic organs...
  30. ncbi request reprint Up-regulation of tyrosine kinase (Trka, Trkb) receptor expression and phosphorylation in lumbosacral dorsal root ganglia after chronic spinal cord (T8-T10) injury
    Liya Qiao
    Department of Neurology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    J Comp Neurol 449:217-30. 2002
    ..Neuroplasticity of lower urinary tract reflexes after SCI may be mediated by both nerve growth factor and brain-derived neurotrophic factor...
  31. ncbi request reprint Increased expression of neuronal nitric oxide synthase in bladder afferent cells in the lumbosacral dorsal root ganglia after chronic bladder outflow obstruction
    Peter Zvara
    Department of Surgery, University of Vermont, D319 Given Bldg, 89 Beaumont Ave, Burlington, VT 05405, USA
    Brain Res 1002:35-42. 2004
    ..8-fold in males and 1.9-fold in females) and S1 (2.8-fold in males and 5.3-fold in females) DRG. In contrast, no changes in nNOS-IR in neurons or fiber distribution were observed in any spinal cord segments examined...
  32. ncbi request reprint COX-2 and prostanoid expression in micturition pathways after cyclophosphamide-induced cystitis in the rat
    V Y Hu
    Departments of Neurology, Anatomy and Neurobiology, and Surgery, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    Am J Physiol Regul Integr Comp Physiol 284:R574-85. 2003
    ..These studies suggest an involvement of urinary bladder COX-2 and its metabolites in altered micturition reflexes with CYP-induced cystitis...
  33. pmc Involvement of JAK-STAT signaling/function after cyclophosphamide-induced bladder inflammation in female rats
    Bopaiah P Cheppudira
    Dept of Neurology, Univ of Vermont College of Medicine, Burlington, VT 05405, USA
    Am J Physiol Renal Physiol 297:F1038-44. 2009
    ..These studies demonstrate a potential role for JAK-STAT signaling pathways in bladder hyperreflexia and referred pain induced by CYP-induced bladder inflammation...
  34. pmc Corticotropin-releasing factor (CRF) expression in postnatal and adult rat sacral parasympathetic nucleus (SPN)
    Simon Studeny
    Department of Neurology, University of Vermont College of Medicine, D415A Given Research Building, Burlington, VT, 05405, USA
    Cell Tissue Res 322:339-52. 2005
    ..The upregulation of CRF-IR in bulbospinal projections to the SPN may contribute to mature voiding reflexes...
  35. pmc Distribution and fate of cocaine- and amphetamine-regulated transcript peptide (CARTp)-expressing cells in rat urinary bladder: a developmental study
    Katarina Zvarova
    Department of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Comp Neurol 489:501-17. 2005
    ..This study demonstrates that CARTp-IR intramural ganglia and CARTp-IR paraganglion or SIF cells exist in the postnatal and adult rat bladder, although the role of these cell types remains to be determined...
  36. ncbi request reprint Up-regulation of protease activated receptors in bladder after cyclophosphamide induced cystitis and colocalization with capsaicin receptor (VR1) in bladder nerve fibers
    Abbey Dattilio
    Department of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Urol 173:635-9. 2005
    ..Studies suggest a neurogenic mechanism for PAR2 in inflammation and the fact that interaction between PAR2 and transient receptor vanilloid receptor (TRPV1 or VR1) are important for the induction and maintenance of inflammatory pain...
  37. pmc Postnatal expression of corticotropin releasing factor (CRF) in rat urinary bladder
    Jennifer LaBerge
    Department of Neurology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Auton Neurosci 141:83-93. 2008
    ..Changes in CRF expression and neuropeptide expression in general in the urinary bladder may contribute to the emergence of mature voiding reflexes...
  38. ncbi request reprint The weight loss elicited by cobalt protoporphyrin is related to decreased activity of nitric oxide synthase in the hypothalamus
    Muyao Li
    Department of Medicine, University of Vermont, C209 Given Bldg, 89 Beaumont Ave, Burlington, Vermont 05405, USA
    J Appl Physiol 100:1983-91. 2006
    ..We also demonstrate that CoPP decreases NOS activity but that it paradoxically increases neuronal NOS transcript expression and increases neuronal NOS protein content on Western blotting...
  39. ncbi request reprint Cyclophosphamide induced cystitis alters neurotrophin and receptor tyrosine kinase expression in pelvic ganglia and bladder
    Elaine Murray
    Department of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Urol 172:2434-9. 2004
    ..We examined neurotrophin and receptor tyrosine kinase (Trk) expression in the bladder and major pelvic ganglia (MPG) after cyclophosphamide induced cystitis in rats...
  40. pmc Electrical properties of neurons in the intact rat major pelvic ganglion
    H Tan
    Department of Neurology, University of Vermont College of Medicine, Burlington, VT, 05045, United States
    Auton Neurosci 134:26-37. 2007
    ..A small percentage (<6%) of neurons exhibited spontaneous activity. Taken together these findings are consistent with the concept that neurons in the MPG exhibit heterogeneous electrical properties...
  41. ncbi request reprint Changes in urinary bladder cytokine mRNA and protein after cyclophosphamide-induced cystitis
    Susan E Malley
    University of Vermont, College of Medicine, Department of Neurology, Burlington, Vermont 05405, USA
    Physiol Genomics 9:5-13. 2002
    ..Increased cytokine expression after CYP-induced cystitis, alone or in combination with other inflammatory mediators or growth factors, may contribute to altered lower urinary tract function after cystitis...
  42. pmc P2X2 and P2X3 receptor expression in postnatal and adult rat urinary bladder and lumbosacral spinal cord
    Simon Studeny
    University of Vermont College of Medicine, Department of Neurology, Burlington, VT 05405, USA
    Am J Physiol Regul Integr Comp Physiol 289:R1155-68. 2005
    ..These studies demonstrate plastic expression of P2X2 and P2X3 receptors in bladder and spinal cord during early postnatal development at times coincident with appearance of mature voiding patterns...
  43. pmc Role of p75NTR in female rat urinary bladder with cyclophosphamide-induced cystitis
    Mary Beth Klinger
    Dept of Neurology, Univ of Vermont College of Medicine, D415A Given Research Bldg, Burlington, VT 05405, USA
    Am J Physiol Renal Physiol 295:F1778-89. 2008
    ..The overall activity of the urinary bladder reflects the balance of NGF-p75(NTR) and NGF-TrkA signaling...
  44. pmc Expression of fractalkine and fractalkine receptor in urinary bladder after cyclophosphamide (CYP)-induced cystitis
    Ruhin Yuridullah
    University of Vermont College of Medicine, Department of Neurology, Burlington, VT 05405, USA
    Auton Neurosci 126:380-9. 2006
    ....
  45. ncbi request reprint Differential expression of bladder neurotrophic factor mRNA in male and female rats after bladder outflow obstruction
    Peter Zvara
    Department of Surgery, University of Vermont College of Medicine, Burlington, USA
    J Urol 168:2682-8. 2002
    ..We validated a male rat model of bladder outflow obstruction and compared the expression of bladder neurotrophic factor mRNA in male and female rats 6 weeks after bladder outlet obstruction...
  46. pmc Exaggerated expression of inflammatory mediators in vasoactive intestinal polypeptide knockout (VIP-/-) mice with cyclophosphamide (CYP)-induced cystitis
    Beatrice M Girard
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, VT, USA
    J Mol Neurosci 36:188-99. 2008
    ..This shift in balance may contribute to increased bladder dysfunction in VIP(-/-) mice with bladder inflammation and altered neurochemical expression in micturition pathways...
  47. ncbi request reprint PACAP enhances mouse urinary bladder contractility and is upregulated in micturition reflex pathways after cystitis
    Gerald M Herrera
    University of Vermont College of Medicine, Department of Neurology, D411 Given Building, Burlington, VT 05405, USA
    Ann N Y Acad Sci 1070:330-6. 2006
    ..PACAP immunoreactivity (IR) is increased in micturition reflex pathways following cystitis. PACAP may contribute to altered sensation and bladder overactivity in the chronic bladder inflammatory syndrome, interstitial cystitis...
  48. ncbi request reprint Decrease in bladder overactivity with REN1820 in rats with cyclophosphamide induced cystitis
    Vivian Y Hu
    Departments of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Urol 173:1016-21. 2005
    ..Studies were performed to determine the NGF dependence of cyclophosphamide (CYP) induced changes in bladder function using the recombinant NGF sequestering protein REN1820...
  49. pmc Urinary bladder function and somatic sensitivity in vasoactive intestinal polypeptide (VIP)-/- mice
    Simon Studeny
    Department of Neurology, University of Vermont College of Medicine, D415A Given Research Building, Burlington, VT 05405, USA
    J Mol Neurosci 36:175-87. 2008
    ..Thus, these changes may further regulate the neural control of micturition...
  50. ncbi request reprint A role for pituitary adenylate cyclase activating polypeptide (PACAP) in detrusor hyperreflexia after spinal cord injury (SCI)
    Peter Zvara
    University of Vermont College of Medicine, Department of Neurology, D411 Given Building, Burlington, VT 05405, USA
    Ann N Y Acad Sci 1070:622-8. 2006
    ..PACAP may contribute to detrusor hyperreflexia induced by SCI and PACAP antagonists may be a novel approach to reduce detrusor hyperreflexia after SCI...