D M Virshup

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. ncbi request reprint Protein phosphatase 2A: a panoply of enzymes
    D M Virshup
    Departments of Pediatrics and Oncological Sciences, 5C334 School of Medicine, University of Utah, Salt Lake City, 84132, USA david
    Curr Opin Cell Biol 12:180-5. 2000
  2. pmc Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus
    X Li
    Department of Oncological Sciences and the Center for Children, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA
    EMBO J 20:4122-31. 2001
  3. ncbi request reprint Reversible protein phosphorylation regulates circadian rhythms
    D M Virshup
    Department of Pediatrics, University of Utah, Salt Lake City, Utah 84112, USA
    Cold Spring Harb Symp Quant Biol 72:413-20. 2007
  4. pmc Nuclear export of mammalian PERIOD proteins
    E L Vielhaber
    Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112 5550, USA
    J Biol Chem 276:45921-7. 2001
  5. ncbi request reprint Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A
    J M Seeling
    Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84132, USA
    Science 283:2089-91. 1999
  6. ncbi request reprint An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome
    K L Toh
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    Science 291:1040-3. 2001

Collaborators

  • X Li
  • R T Moon
  • L J Ptacek
  • E L Vielhaber
  • K L Toh
  • J M Seeling
  • Y He
  • C R Jones
  • K S Ullman
  • D Duricka
  • W A Hinz
  • E J Eide
  • Y H Fu
  • J R Miller
  • R Gil
  • R White

Detail Information

Publications6

  1. ncbi request reprint Protein phosphatase 2A: a panoply of enzymes
    D M Virshup
    Departments of Pediatrics and Oncological Sciences, 5C334 School of Medicine, University of Utah, Salt Lake City, 84132, USA david
    Curr Opin Cell Biol 12:180-5. 2000
    ..During the past year, studies have shown that protein phosphatase 2A influences events ranging from the initiation of DNA replication to vertebrate axis formation to apoptosis...
  2. pmc Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus
    X Li
    Department of Oncological Sciences and the Center for Children, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA
    EMBO J 20:4122-31. 2001
    ..These results support the hypothesis that PP2A:B56 directly inhibits Wnt signaling and plays a role in development and carcinogenesis...
  3. ncbi request reprint Reversible protein phosphorylation regulates circadian rhythms
    D M Virshup
    Department of Pediatrics, University of Utah, Salt Lake City, Utah 84112, USA
    Cold Spring Harb Symp Quant Biol 72:413-20. 2007
    ..Pharmacological manipulation of rhythms could mitigate stress from jet lag, shift work, and perhaps even seasonal affective disorder...
  4. pmc Nuclear export of mammalian PERIOD proteins
    E L Vielhaber
    Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112 5550, USA
    J Biol Chem 276:45921-7. 2001
    ..The presence of a functional NES in mPER1 and mPER2 as well as related sequences in a variety of other PER proteins suggests that nuclear export may be a conserved and important feature of circadian regulators...
  5. ncbi request reprint Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A
    J M Seeling
    Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84132, USA
    Science 283:2089-91. 1999
    ..B56 may direct PP2A to dephosphorylate specific components of the APC-dependent signaling complex and thereby inhibit Wnt signaling...
  6. ncbi request reprint An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome
    K L Toh
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    Science 291:1040-3. 2001
    ..Thus, a variant in human sleep behavior can be attributed to a missense mutation in a clock component, hPER2, which alters the circadian period...