L P Villarreal

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Viruses and host evolution: virus-mediated self identity
    Luis Villarreal
    Center for Virus Research, University of California, Irvine, CA, USA
    Adv Exp Med Biol 738:185-217. 2012
  2. ncbi A hypothesis for DNA viruses as the origin of eukaryotic replication proteins
    L P Villarreal
    Departments of Molecular Biology and Biochemistry, University of California, Irvine, California 92697, USA
    J Virol 74:7079-84. 2000
  3. ncbi Viral ancestors of antiviral systems
    Luis P Villarreal
    Center for Virus Research, University of California, Irvine, CA 92697, USA
    Viruses 3:1933-58. 2011
  4. ncbi The source of self: genetic parasites and the origin of adaptive immunity
    Luis P Villarreal
    Center for Virus Research, Department of Molecular Biology and Biochemistry, University of California, Irvine, California 92697, USA
    Ann N Y Acad Sci 1178:194-232. 2009
  5. ncbi Persistence pays: how viruses promote host group survival
    Luis P Villarreal
    Center for Virus Research, University of California, Irvine, CA 92697, USA
    Curr Opin Microbiol 12:467-72. 2009
  6. ncbi Structural proteomics of the poxvirus family
    Arlo Z Randall
    Department of Information and Computer Science, University of California, Irvine, CA 92697 3425, USA
    Artif Intell Med 31:105-15. 2004
  7. ncbi Viruses are essential agents within the roots and stem of the tree of life
    Luis P Villarreal
    Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697, USA
    J Theor Biol 262:698-710. 2010
  8. ncbi E1A represses wild-type and F9-selected polyomavirus DNA replication by a mechanism not requiring depression of large tumor antigen transcription
    N J DePolo
    Department of Molecular Biology and Biochemistry, University of California, Irvine 92717
    J Virol 65:2921-8. 1991
  9. ncbi Natural biology of polyomavirus middle T antigen
    K A Gottlieb
    Department of Molecular Biology and Biochemistry, Biological Sciences II, University of California-Irvine, Irvine, CA 92697, USA
    Microbiol Mol Biol Rev 65:288-318 ; second and third pages, table of contents. 2001
  10. ncbi Detection of human polyomaviruses and papillomaviruses in prostatic tissue reveals the prostate as a habitat for multiple viral infections
    Alberto Zambrano
    Department of Molecular Biology and Biochemistry, University of California at Irvine, California 92697, USA
    Prostate 53:263-76. 2002

Research Grants

  1. Post-Baccalaureate Research Education Program (PREP)
    Luis Villarreal; Fiscal Year: 2007

Collaborators

Detail Information

Publications12

  1. ncbi Viruses and host evolution: virus-mediated self identity
    Luis Villarreal
    Center for Virus Research, University of California, Irvine, CA, USA
    Adv Exp Med Biol 738:185-217. 2012
    ..The role of addiction modules in the origin of extended social bonding of humans is outlined and applied to the emergence of language as a system of group identity...
  2. ncbi A hypothesis for DNA viruses as the origin of eukaryotic replication proteins
    L P Villarreal
    Departments of Molecular Biology and Biochemistry, University of California, Irvine, California 92697, USA
    J Virol 74:7079-84. 2000
    ..We consider arguments for the polarity of this relationship and present the hypothesis that the replication genes of DNA viruses gave rise to those of eukaryotes and not the reverse direction...
  3. ncbi Viral ancestors of antiviral systems
    Luis P Villarreal
    Center for Virus Research, University of California, Irvine, CA 92697, USA
    Viruses 3:1933-58. 2011
    ..I conclude with a reexamination of the 'Big Bang' theory for the emergence of the adaptive immune system in vertebrates by horizontal transfer and note how viruses could have and did provide crucial and coordinated features...
  4. ncbi The source of self: genetic parasites and the origin of adaptive immunity
    Luis P Villarreal
    Center for Virus Research, Department of Molecular Biology and Biochemistry, University of California, Irvine, California 92697, USA
    Ann N Y Acad Sci 1178:194-232. 2009
    ..It is concluded that colonization by viruses and their defectives provides a more coherent explanation for the origin of adaptive immunity...
  5. ncbi Persistence pays: how viruses promote host group survival
    Luis P Villarreal
    Center for Virus Research, University of California, Irvine, CA 92697, USA
    Curr Opin Microbiol 12:467-72. 2009
    ..This virus-centric re-examination concludes that viruses can indeed affect and promote relative group selection...
  6. ncbi Structural proteomics of the poxvirus family
    Arlo Z Randall
    Department of Information and Computer Science, University of California, Irvine, CA 92697 3425, USA
    Artif Intell Med 31:105-15. 2004
    ..Inclusion of additional poxvirus genomes in the PPDB is in progress. The PPDB has an upward scalable informatics infrastructure that can readily be applied to viral, bacterial, as well as eukaryotic genomes...
  7. ncbi Viruses are essential agents within the roots and stem of the tree of life
    Luis P Villarreal
    Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697, USA
    J Theor Biol 262:698-710. 2010
    ..In this article we will show that these features are not coherent with current knowledge about viruses but that viral agents play key roles within the roots and stem of the tree of life...
  8. ncbi E1A represses wild-type and F9-selected polyomavirus DNA replication by a mechanism not requiring depression of large tumor antigen transcription
    N J DePolo
    Department of Molecular Biology and Biochemistry, University of California, Irvine 92717
    J Virol 65:2921-8. 1991
    ..This suggests that E1A may repress Py DNA replication by a more direct mechanism, possibly by blocking enhancer activation of DNA replication in a manner uncoupled with enhancer transcriptional control...
  9. ncbi Natural biology of polyomavirus middle T antigen
    K A Gottlieb
    Department of Molecular Biology and Biochemistry, Biological Sciences II, University of California-Irvine, Irvine, CA 92697, USA
    Microbiol Mol Biol Rev 65:288-318 ; second and third pages, table of contents. 2001
    ..It is from this context that our current understanding of this well-studied virus and gene is presented...
  10. ncbi Detection of human polyomaviruses and papillomaviruses in prostatic tissue reveals the prostate as a habitat for multiple viral infections
    Alberto Zambrano
    Department of Molecular Biology and Biochemistry, University of California at Irvine, California 92697, USA
    Prostate 53:263-76. 2002
    ..The prostate is a complex habitat where mixed infections with oncogenic DNA viruses frequently occur and opens the discussion to the potential role of these viruses in the cancer of the prostate...
  11. ncbi Evidence of diversifying selection in human papillomavirus type 16 E6 but not E7 oncogenes
    Victor R DeFilippis
    Department of Ecology and Evolutionary Biology, University of California Irvine, Irvine, CA 92697, USA
    J Mol Evol 55:491-9. 2002
    ..The amino acid compositions and locations of selected sites are described. Possible sources of natural selection including antiviral immune pressure and polymorphism of host cellular proteins are discussed...
  12. ncbi Are viruses alive?
    Luis P Villarreal
    Center for Virus Research, University of California, Irvine, USA
    Sci Am 291:100-5. 2004

Research Grants3

  1. Post-Baccalaureate Research Education Program (PREP)
    Luis Villarreal; Fiscal Year: 2007
    ....