Research Topics
| S VijanSummaryAffiliation: University of Michigan Country: USA Publications
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Publications
Multivariable risk prediction can greatly enhance the statistical power of clinical trial subgroup analysisRodney A Hayward
Department of Veterans Affairs, VA Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
BMC Med Res Methodol 6:18. 2006..conventional subgroup analysis...
Cost-utility analysis of screening intervals for diabetic retinopathy in patients with type 2 diabetes mellitusS Vijan
Veterans Affairs Health Services Research and Development Quality Enhancement Research Initiative and the Michigan Diabetes Research and Training Center, University of Michigan, Ann Arbor 48113 0170, USA
JAMA 283:889-96. 2000..However, the benefit of annual vs less frequent screening intervals has not been well evaluated, especially for low-risk patients...
Treatment of hypertension in type 2 diabetes mellitus: blood pressure goals, choice of agents, and setting priorities in diabetes careSandeep Vijan
Veterans Affairs Health Services Research, Development Center for Practice Management and Outcomes Research, P O Box 130170, Ann Arbor, Michigan 48113 0170, USA
Ann Intern Med 138:593-602. 2003..Hypertension in patients with type 2 diabetes mellitus is a prevalent condition that leads to substantial morbidity and mortality...
Pharmacologic lipid-lowering therapy in type 2 diabetes mellitus: background paper for the American College of PhysiciansSandeep Vijan
Veterans Affairs Health Services Research and Development Center for Practice Management and Outcomes Research, University of Michigan, Ann Arbor 48105, USA
Ann Intern Med 140:650-8. 2004..Cardiovascular disease is the primary complication and cause of death in patients with type 2 diabetes mellitus. Modification of cardiovascular risk factors may improve patient outcomes...
Brief report: the burden of diabetes therapy: implications for the design of effective patient-centered treatment regimensSandeep Vijan
Veterans Affairs Center for Practice Management and Outcomes Research, Ann Arbor, MI, USA
J Gen Intern Med 20:479-82. 2005..Management of diabetes, and in particular blood glucose, can be complex and burdensome...
Should we abandon QALYs as a resource allocation tool?Sandeep Vijan
Veterans Affairs Health Services Research and Development Center for Practice Management and Outcomes Research, Ann Arbor, Michigan, USA
Pharmacoeconomics 24:953-4. 2006
Projections of demand and capacity for colonoscopy related to increasing rates of colorectal cancer screening in the United StatesS Vijan
Veterans Affairs Health Services Research and Development HSR and D, Ann Arbor, MI 48105, USA
Aliment Pharmacol Ther 20:507-15. 2004..There is debate about the optimal colorectal cancer screening test, partly because of concerns about colonoscopy demand...
Screening, prevention, counseling, and treatment for the complications of type II diabetes mellitus. Putting evidence into practiceS Vijan
Division of General Internal Medicine, University of Michigan, Ann Arbor, USA
J Gen Intern Med 12:567-80. 1997..Implementation of these practices has the potential to significantly improve quality of life and increase life expectancy in patients with type II diabetes mellitus...
Which colon cancer screening test? A comparison of costs, effectiveness, and complianceS Vijan
The Veterans Affairs Center for Practice Management and Outcomes Research, Ann Arbor, Michigan 48113 0170, USA
Am J Med 111:593-601. 2001..We sought to determine the cost effectiveness of different screening strategies for colorectal cancer at levels of compliance likely to be achieved in clinical practice...
The cost-utility of screening for depression in primary careM Valenstein
Health Services Research and Development, Department of Veterans Affairs Medical Center, Box 130170, Ann Arbor, MI 48113-0170, USA
Ann Intern Med 134:345-60. 2001..CONCLUSIONS: Annual and periodic screening for depression cost more than $50 000/QALY, but one-time screening is cost-effective. The cost-effectiveness of screening is likely to improve if treatment becomes more effective...
The impact of diabetes on workforce participation: results from a national household sampleSandeep Vijan
Vetterans Affairs Center for Practice Management and Outcomes Research, Ann Arbor, MI, USA
Health Serv Res 39:1653-69. 2004..Given the rising prevalence of diabetes, these costs are likely to increase substantially unless countered by better public health or medical interventions...
Barriers to following dietary recommendations in Type 2 diabetesS Vijan
Veterans Affairs Center for Practice Management and Outcomes Research, Ann Arbor, MI, USA
Diabet Med 22:32-8. 2005..To evaluate barriers to following dietary recommendations in patients with Type 2 diabetes...
Narrative review: lack of evidence for recommended low-density lipoprotein treatment targets: a solvable problemRodney A Hayward
Department of Veterans Affairs, VA Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, and University of Michigan Schools of Medicine and Public Health, Ann Arbor, Michigan 48113 0170, USA
Ann Intern Med 145:520-30. 2006....
Cost-effectiveness of a microvolt T-wave alternans screening strategy for implantable cardioverter-defibrillator placement in the MADIT-II-eligible populationPaul S Chan
VA Center for Practice Management and Outcomes Research, Ann Arbor, Michigan, USA
J Am Coll Cardiol 48:112-21. 2006....
Cost-effectiveness of radiofrequency catheter ablation for atrial fibrillationPaul S Chan
Division of Cardiology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA
J Am Coll Cardiol 47:2513-20. 2006..We sought to compare the cost-effectiveness of left atrial catheter ablation (LACA), amiodarone, and rate control therapy in the management of atrial fibrillation (AF)...
A cost/utility analysis of open reduction and internal fixation versus cast immobilization for acute nondisplaced mid-waist scaphoid fracturesErika N Davis
Department of Surgery, Veterans Affairs Medical Center, University of Michigan Medical School, Ann Arbor, Michigan, USA
Plast Reconstr Surg 117:1223-35; discussion 1236-8. 2006..When considering only direct costs, open reduction and internal fixation is cost-effective relative to other widely accepted interventions...
Effectiveness of implantable cardioverter-defibrillators in patients with ischemic heart disease and left ventricular dysfunctionPaul S Chan
Division of Cardiology, University of Michigan, Ann Arbor, USA
Arch Intern Med 166:2228-33. 2006..To investigate the generalizabilty of this mortality reduction, we examined the effectiveness of ICDs in clinical practice...
Determinants of colorectal cancer screening use, attempts, and non-useNancy K Janz
Department of Health Behavior and Health Education, University of Michigan School of Public Health, 1420 Washington Heights, Ann Arbor, MI 48109 2029, USA
Prev Med 44:452-8. 2007....
Depression among older adults in the United States and EnglandKara Zivin
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, 48109, USA
Am J Geriatr Psychiatry 18:1036-44. 2010..Depression negatively affects health and well being among older adults, but there have been no nationally representative comparisons of depression prevalence among older adults in England and the United States...
Surveillance colonoscopy is cost-effective for patients with adenomas who are at high risk of colorectal cancerSameer D Saini
Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, Michigan, USA
Gastroenterology 138:2292-9, 2299.e1. 2010..Guidelines recommend that patients with colon adenomas undergo periodic surveillance colonoscopy. The purpose of this study was to estimate the cost-effectiveness of these recommendations...
Optimizing statin treatment for primary prevention of coronary artery diseaseRodney A Hayward
University of Michigan and Veteran Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, USA
Ann Intern Med 152:69-77. 2010....
Hospitalizations and deaths among adults with cardiovascular disease who underuse medications because of cost: a longitudinal analysisMichele Heisler
Veterans Affairs Center for Clinical Practice Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI 48113 0170, USA
Med Care 48:87-94. 2010..Less is known about the extent to which such cost-related medication underuse is associated with increases in subsequent hospitalizations and deaths...
The relative merits of population-based and targeted prevention strategiesDonna M Zulman
Robert Wood Johnson Clinical Scholars Program, University of Michigan, 6312 Medical Science Building I, 1150 W Medical Center Drive, Ann Arbor, MI 48109 5604, USA
Milbank Q 86:557-80. 2008..The use of multivariable risk prediction tools, however, may affect the relative merits of this strategy...
Diabetes control with reciprocal peer support versus nurse care management: a randomized trialMichele Heisler
University of Michigan and Ann Arbor Veterans Affairs Health Care System, Ann Arbor, Michigan 48113 0170, USA
Ann Intern Med 153:507-15. 2010..Resource barriers complicate diabetes care management. Support from peers may help patients manage their diabetes...
Incremental benefit and cost-effectiveness of high-dose statin therapy in high-risk patients with coronary artery diseasePaul S Chan
University of Michigan Department of Internal Medicine, Ann Arbor, MI, USA
Circulation 115:2398-409. 2007..However, the actual benefit and cost-effectiveness of high-dose statin therapy are unknown...
Efficacy and cost of postpartum screening strategies for diabetes among women with histories of gestational diabetes mellitusCatherine Kim
Department of Internal Medicine, Division of General Medicine, University of Michigan, Ann Arbor, Michigan, USA
Diabetes Care 30:1102-6. 2007..To compare the cost and time to diagnosis associated with several screening strategies for diabetes in women with histories of gestational diabetes mellitus (GDM)...
Glycemic control and absenteeism among individuals with diabetesKaan Tunceli
Center for Health Services Research, Henry Ford Health System, Detroit, Michigan, USA
Diabetes Care 30:1283-5. 2007
The value of coronary heart disease care for the elderly: 1987-2002Allison B Rosen
University of Michigan and Ann Arbor Veterans Affairs, USA
Health Aff (Millwood) 26:111-23. 2007..Overall, the value of our CHD spending is quite good. Despite this wise investment of resources to date, considerable opportunities remain for additional investment to improve the adoption of valuable but underused health services...
Reporting clinical trial results to inform providers, payers, and consumersRodney A Hayward
Department of Veterans Affairs VA Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, University of Michigan, USA
Health Aff (Millwood) 24:1571-81. 2005....
When do patients and their physicians agree on diabetes treatment goals and strategies, and what difference does it make?Michele Heisler
Veterans Affairs Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, Ann Arbor, MI 48113 0170, USA
J Gen Intern Med 18:893-902. 2003..However, this hypothesis has not been tested in actual encounters of patients with their own physicians...
Extent and cost of informal caregiving for older Americans with symptoms of depressionKenneth M Langa
Division of General Medicine, University of Michigan Health System, 300 North Ingalls Building, Room 7E01, Box 0429, Ann Arbor, MI 48109 0429, USA
Am J Psychiatry 161:857-63. 2004..The purpose of this study was to obtain nationally representative estimates of the additional time and cost associated with informal caregiving for older Americans with depressive symptoms...
Aspirin use and counseling about aspirin among patients with diabetesSarah L Krein
Department of Veterans Affairs Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan 48113
Diabetes Care 25:965-70. 2002..This study examines current physician practices and the use of aspirin therapy by individuals with diabetes...
Impact of patient risk on the hospital volume-outcome relationship in coronary artery bypass graftingBrahmajee K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, 48109 0366, USA
Arch Intern Med 165:333-7. 2005..We assessed (1) whether in-hospital mortality rates differ across lower- and higher-volume hospitals by expected surgical risk and (2) whether high-risk patients are more likely to undergo CABG at low-volume centers...
Informal caregiving for diabetes and diabetic complications among elderly americansKenneth M Langa
Division of General Medicine, Department of Medicine, University of Michigan, Ann Arbor 48109 0429, USA
J Gerontol B Psychol Sci Soc Sci 57:S177-86. 2002....
The relationship between knowledge of recent HbA1c values and diabetes care understanding and self-managementMichele Heisler
HSR and D Field Program, Veterans Affairs Center for Practice Management, VA Ann Arbor Healthcare System, P O Box 130170, 11H, Ann Arbor, MI 48113, USA
Diabetes Care 28:816-22. 2005....
Cost-effectiveness of full medicare coverage of angiotensin-converting enzyme inhibitors for beneficiaries with diabetesAllison B Rosen
Division of General Medicine, University of Michigan Health Systems, 300 North Ingalls, Suite 7E10, Ann Arbor, MI 48109, USA
Ann Intern Med 143:89-99. 2005..Angiotensin-converting enzyme (ACE) inhibitors slow renal disease progression and reduce cardiac morbidity and mortality in patients with diabetes. Patients' out-of-pocket costs pose a barrier to using this effective therapy...
Getting heavier, younger: trajectories of obesity over the life courseJ M Lee
Division of Pediatric Endocrinology, University of Michigan, Ann Arbor, MI 48109 5456, USA
Int J Obes (Lond) 34:614-23. 2010..Such trends may have implications for the prevalence of obesity-associated conditions among population subgroups, including type 2 diabetes...
Avoiding pitfalls in chronic disease quality measurement: a case for the next generation of technical quality measuresE A Kerr
Veterans Affairs Center for Practice Management and Outcomes Research, Veterans Affairs Ann Arbor Healthcare System, MI 48113 0170, USA
Am J Manag Care 7:1033-43. 2001..We believe that using more tightly linked measures in quality assessment will identify important quality of care problems and is more likely to produce improved outcomes for those with chronic diseases...
Beyond utilitarianism: a method for analyzing competing ethical principles in a decision analysis of liver transplantationMichael L Volk
Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan 48109, USA
Med Decis Making 28:763-72. 2008..In this study, the authors examine a method to incorporate competing ethical principles in a decision analysis of liver transplantation for a patient with acute liver failure (ALF)...
The cost-effectiveness of CT colonography in screening for colorectal neoplasiaSandeep Vijan
Veterans Affairs Health Services Research and Development Center for Practice Management and Outcomes Research, Ann Arbor, Michigan 48105, USA
Am J Gastroenterol 102:380-90. 2007..We examined the cost-effectiveness of 2- and 3-dimensional computerized tomography (CT) colonography as a screening test for colorectal neoplasia...
The impact of a celebrity promotional campaign on the use of colon cancer screening: the Katie Couric effectPeter Cram
Division of General Medicine, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, USA
Arch Intern Med 163:1601-5. 2003..These findings suggest that a celebrity spokesperson can have a substantial impact on public participation in preventive care programs...
Proactive case management of high-risk patients with type 2 diabetes mellitus by a clinical pharmacist: a randomized controlled trialHae Mi Choe
College of Pharmacy, University of Michigan, Ann Arbor, USA
Am J Manag Care 11:253-60. 2005..This approach, integrated with and based in the primary care setting, was an effective and efficient approach to improving care, especially for those with poor glycemic control at baseline...
A novel model measuring the harm of transplanting hepatocellular carcinoma exceeding Milan criteriaM L Volk
Division of Gastroenterology, University of Michigan Health System, 6312 Medical Science Building 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA
Am J Transplant 8:839-46. 2008..In regions with less severe organ shortage, a more aggressive approach to transplanting these patients may be justified...
The role of hospital volume in coronary artery bypass grafting: is more always better?B K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109 0366, USA
J Am Coll Cardiol 38:1923-30. 2001..The goal of this study was to determine whether outcomes of nonemergent coronary artery bypass grafting (CABG) differed between low- and high-volume hospitals in patients at different levels of surgical risk...
Case management for patients with poorly controlled diabetes: a randomized trialSarah L Krein
VA Health Services Research and Development Center for Practice Management and Outcomes Research, Ann Arbor, Michigan 48113 0170, USA
Am J Med 116:732-9. 2004..To evaluate the effects of a collaborative case management intervention for patients with poorly controlled type 2 diabetes on glycemic control, intermediate cardiovascular outcomes, satisfaction with care, and resource utilization...
Quality indicators for the care of diabetes mellitus in vulnerable eldersPaul Shekelle
RAND Health, Santa Monica, CA 90407, USA
J Am Geriatr Soc 55:S312-7. 2007
Glycemic control and type 2 diabetes mellitus: the optimal hemoglobin A1c targets. A guidance statement from the American College of PhysiciansAmir Qaseem
American College of Physicians, Philadelphia, Pennsylvania 19106, USA
Ann Intern Med 147:417-22. 2007..STATEMENT 3: We recommend further research to assess the optimal level of glycemic control, particularly in the presence of comorbid conditions...
Intensive glucose control in elderly adultsRodney A Hayward
JAMA 297:2195; author reply 2196. 2007
Predicted quality-adjusted life years as a composite measure of the clinical value of diabetes risk factor controlJulie Schmittdiel
Kaiser Permanente Northern California Division of Research, Oakland, California 94612, USA
Med Care 45:315-21. 2007..These quality indicators often are examined separately and weighted equally in performance measurement, potentially discarding important information...
Cost-effectiveness of in-home automated external defibrillators for individuals at increased risk of sudden cardiac deathPeter Cram
Division of General Medicine, Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA, USA
J Gen Intern Med 20:251-8. 2005..The current study was conducted to explore the relationship between individuals' risk of cardiac arrest and cost-effectiveness of in-home AED deployment...
The value of medical spending in the United States, 1960-2000David M Cutler
Department of Economics, Harvard University, and the National Bureau of Economic Research, Cambridge, Mass 02138, USA
N Engl J Med 355:920-7. 2006..The increased use of medical therapies has led to increased medical costs. To provide insight into the value of this increased spending, we compared gains in life expectancy with the increased costs of care from 1960 through 2000...
Implantable or external defibrillators for individuals at increased risk of cardiac arrest: where cost-effectiveness hits fiscal realityPeter Cram
University of Iowa College of Medicine, Iowa City, IA, USA
Value Health 9:292-302. 2006..We used decision analysis to evaluate the clinical and economic trade-offs of AEDs, ICDs, and emergency medical services equipped with defibrillators (EMS-D) for reducing cardiac arrest mortality...
Tissue plasminogen activator was cost-effective compared to streptokinase in only selected patients with acute myocardial infarctionDavid M Kent
Clinical Research and Health Policy Studies, Tufts New England Medical Center Tufts University School of Medicine, 750 Washington Street, Box 63, Boston, MA 02111, USA
J Clin Epidemiol 57:843-52. 2004..We sought to explore the patient-specific cost-effectiveness in a community-based sample for a therapy for which the average cost-effectiveness in a clinical trial has been well-described...
The economic burden of major adult visual disorders in the United StatesDavid B Rein
RTI International, Research Triangle Park, NC, USA
Arch Ophthalmol 124:1754-60. 2006....
Cost-effectiveness of automated external defibrillator deployment in selected public locationsPeter Cram
Division of General Medicine, Department of Internal Medicine, University of Iowa College of Medicine, 200 Hawkins Drive, 6SE GH, Iowa City, IA 52242, USA
J Gen Intern Med 18:745-54. 2003..We sought to evaluate the cost-effectiveness of the AHA recommendation and of AED deployment in selected public locations with known cardiac arrest rates...
An independently derived and validated predictive model for selecting patients with myocardial infarction who are likely to benefit from tissue plasminogen activator compared with streptokinaseDavid M Kent
Division of Clinical Care Research, Department of Medicine, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
Am J Med 113:104-11. 2002..3% 30-day mortality, compared with a mortality of 7.3% among those treated with streptokinase, despite a greater risk of intracranial hemorrhage with tPA. However, in part because of its higher cost, tPA has not been adopted universally...
Public use of automated external defibrillatorsPeter Cram
N Engl J Med 348:755-6; author reply 755-6. 2003
Quality improvement strategies for type 2 diabetesSarah L Krein
JAMA 296:2680; author reply 2681. 2006
The impact of including passive benefits in cost-effectiveness analysis: the case of automated external defibrillators on commercial aircraftPeter Cram
Department of Internal Medicine, University of Iowa School of Medicine, Iowa City, IA, USA
Value Health 6:466-73. 2003..Further research should attempt to clarify the magnitude and percentage of patients who receive passive benefit...
Automated external defibrillator deployment in high schools and senior centersElizabeth Jones
Iowa City Veterans Affairs Medical, Center, Division of General Medicine, Department of Internal, Medicine, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
Prehosp Emerg Care 9:382-5. 2005..CONCLUSION: The availability of AEDs across different sites may not correspond directly to the risk of cardiac arrest at these sites...
Research Grants
- Cost-effectiveness of genetic screening for colon cancerSandeep Vijan; Fiscal Year: 2006..Outcome measures: The risks of developing or dying from CRC, the costs of screening, and the incremental cost-effectiveness of various screening regimens. ..
