A R Vieira

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Genome-wide association scan of dental caries in the permanent dentition
    Xiaojing Wang
    Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, 15219, USA
    BMC Oral Health 12:57. 2012
  2. pmc Genetics and caries: prospects
    Alexandre Rezende Vieira
    Departments of Oral Biology and Pediatric Dentistry, and Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Braz Oral Res 26:7-9. 2012
  3. doi request reprint Summary of the IADR Cariology Research Group Symposium, Barcelona, Spain, July 2010: new directions in cariology research
    A R Vieira
    University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA
    Caries Res 46:346-52. 2012
  4. doi request reprint Genetic and environmental factors in human cleft lip and palate
    Alexandre R Vieira
    Department of Oral Biology, University of Pittsburgh, Pittsburgh, PA, USA
    Front Oral Biol 16:19-31. 2012
  5. ncbi request reprint Genome-wide scan finds suggestive caries loci
    A R Vieira
    Department of Oral Biology, Universityof Pittsburgh School of Dental Medicine, Pittsburgh, PA 15261, USA
    J Dent Res 87:435-9. 2008
  6. pmc Novel cleft susceptibility genes in chromosome 6q
    A Letra
    Department of Oral Biology and Center for Craniofacial and Dental Genetics, University of Pittsburgh, 614 Salk Hall, 3501 Terrace Street, Pittsburgh, PA 15261, USA
    J Dent Res 89:927-32. 2010
  7. ncbi request reprint Reduced folate carrier 1 (RFC1) is associated with cleft of the lip only
    A R Vieira
    Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, 3501 Terrace Street, Pittsburgh, PA 15261, USA
    Braz J Med Biol Res 41:689-93. 2008
  8. doi request reprint The antimicrobial peptide DEFB1 is associated with caries
    A Ozturk
    Department of Periodontics and Preventive Dentistry, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
    J Dent Res 89:631-6. 2010
  9. doi request reprint Tooth agenesis association with self-reported family history of cancer
    E C Küchler
    Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, 3501 Terrace Street, Pittsburgh, PA 15261, USA
    J Dent Res 92:149-55. 2013
  10. pmc Possible association of amelogenin to high caries experience in a Guatemalan-Mayan population
    K Deeley
    Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Caries Res 42:8-13. 2008

Collaborators

Detail Information

Publications26

  1. pmc Genome-wide association scan of dental caries in the permanent dentition
    Xiaojing Wang
    Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, 15219, USA
    BMC Oral Health 12:57. 2012
    ..Therefore, we conducted the first genome-wide association study (GWAS) to identify genes affecting susceptibility to caries in adults...
  2. pmc Genetics and caries: prospects
    Alexandre Rezende Vieira
    Departments of Oral Biology and Pediatric Dentistry, and Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Braz Oral Res 26:7-9. 2012
    ..We have pioneered the work on genetic studies to identify genes and genetic markers of diagnostic, prognostic, and therapeutic value. This paper summarizes a presentation that elaborated on these initial findings...
  3. doi request reprint Summary of the IADR Cariology Research Group Symposium, Barcelona, Spain, July 2010: new directions in cariology research
    A R Vieira
    University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA
    Caries Res 46:346-52. 2012
    ..This paper summarizes these presentations...
  4. doi request reprint Genetic and environmental factors in human cleft lip and palate
    Alexandre R Vieira
    Department of Oral Biology, University of Pittsburgh, Pittsburgh, PA, USA
    Front Oral Biol 16:19-31. 2012
    ..21 are highlighted, as well as the latest insight from more sophisticated phenotypical characterization and the inclusion of covariables related to the environment in the analysis of genetic variation...
  5. ncbi request reprint Genome-wide scan finds suggestive caries loci
    A R Vieira
    Department of Oral Biology, Universityof Pittsburgh School of Dental Medicine, Pittsburgh, PA 15261, USA
    J Dent Res 87:435-9. 2008
    ..1 and 14q24.3). Genes that may be related to saliva flow and diet preferences are proposed as possible candidates. A protective locus for caries in the X chromosome may explain the gender differences seen in caries frequency...
  6. pmc Novel cleft susceptibility genes in chromosome 6q
    A Letra
    Department of Oral Biology and Center for Craniofacial and Dental Genetics, University of Pittsburgh, 614 Salk Hall, 3501 Terrace Street, Pittsburgh, PA 15261, USA
    J Dent Res 89:927-32. 2010
    ..We provide further evidence of the involvement of chromosome 6q in cleft lip/palate and suggest PRSS35 as a novel candidate gene...
  7. ncbi request reprint Reduced folate carrier 1 (RFC1) is associated with cleft of the lip only
    A R Vieira
    Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, 3501 Terrace Street, Pittsburgh, PA 15261, USA
    Braz J Med Biol Res 41:689-93. 2008
    ..Our results provide a new indication that variation in RFC1 may contribute to cleft lip only. Future studies should investigate the association between oral clefts and RFC1 based on more discrete phenotypes...
  8. doi request reprint The antimicrobial peptide DEFB1 is associated with caries
    A Ozturk
    Department of Periodontics and Preventive Dentistry, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
    J Dent Res 89:631-6. 2010
    ..No association between DEFB1 genetic markers and periodontal disease was found. Our results suggest that functional polymorphisms of DEFB1 are potential markers for caries...
  9. doi request reprint Tooth agenesis association with self-reported family history of cancer
    E C Küchler
    Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, 3501 Terrace Street, Pittsburgh, PA 15261, USA
    J Dent Res 92:149-55. 2013
    ..Prospective studies are needed to confirm if tooth agenesis can be used as a risk marker for cancer...
  10. pmc Possible association of amelogenin to high caries experience in a Guatemalan-Mayan population
    K Deeley
    Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Caries Res 42:8-13. 2008
    ..The approach of comparing individuals with extremely distinct caries experiences could be valuable for decreasing the potential influence of environmental factors on genetic studies of caries...
  11. pmc Insights from studies with oral cleft genes suggest associations between WNT-pathway genes and risk of oral cancer
    P A Andrade Filho
    Department of Otolaryngology and Immunology, Hillman Cancer Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA
    J Dent Res 90:740-6. 2011
    ..001). Additional studies should focus on the identification of potentially functional variants in these genes as contributors to human clefting and oral cancer...
  12. pmc Axis inhibition protein 2 (AXIN2) polymorphisms and tooth agenesis
    N Callahan
    Center for Craniofacial and Dental Genetics, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA 15261, USA
    Arch Oral Biol 54:45-9. 2009
    ..A sub-set of these cases could have an increased susceptibility for colon cancer or other types of tumours and this knowledge would have significant clinical implications...
  13. ncbi request reprint Unraveling human cleft lip and palate research
    A R Vieira
    Departments of Oral Biology and Pediatric Dentistry, School of Dental Medicine, University of Pittsburgh, PA 15261, USA
    J Dent Res 87:119-25. 2008
    ..The latest approaches in cleft research include the analysis of several additional phenotypical features of the population, with the goal of increasing the statistical power of genetics studies...
  14. pmc Defining subphenotypes for oral clefts based on dental development
    A Letra
    Department of Oral Biology and Center for Craniofacial and Dental Genetics, School of Dental Medicine, 614 Salk Hall, University of Pittsburgh, 3501 Terrace Street, Pittsburgh, PA 15261, USA
    J Dent Res 86:986-91. 2007
    ..Agenesis of the lateral incisor on the non-cleft side was the most remarkable observation, and may suggest that such cases could be considered incomplete forms of bilateral clefts of the lip...
  15. ncbi request reprint Molecular factors resulting in tooth agenesis and contemporary approaches for regeneration: a review
    S M Cudney
    Department of Oral Biology, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA 15261, USA
    Eur Arch Paediatr Dent 13:297-304. 2012
    ..Proposed treatment options are presented, including signaling factor supplementation and stem cell isolation for bioengineering new teeth...
  16. doi request reprint The many faces of the genetics contribution to temporomandibular joint disorder
    M Oakley
    Department of Restorative Dentistry Comprehensive Care, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Orthod Craniofac Res 11:125-35. 2008
    ..Review the literature on candidate genes for temporomandibular joint disorder (TMD). Setting and Sample Population - Literature review...
  17. ncbi request reprint The endangered clinical teacher scholar: will this eliminate discovery from the dental school environment?
    M Oakley
    Department of Restorative Dentistry Comprehensive Care, University of Pittsburgh School of Dental Medicine, PA 15261, USA
    J Dent Res 87:200-2. 2008
    ..Without a definitive plan, the clinical scholar will become an endangered species, and the research innovations and discovery of our profession will fall short in addressing the needs of the public's oral and systemic health...
  18. pmc Genome-wide association scan for childhood caries implicates novel genes
    J R Shaffer
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    J Dent Res 90:1457-62. 2011
    ..Verification/replication of suggestive loci may highlight biological mechanisms and/or pathways leading to a fuller understanding of the genetic risks for dental caries...
  19. pmc A genome-wide linkage scan for cleft lip and cleft palate identifies a novel locus on 8p11-23
    B M Riley
    Department of Pediatrics, University of Iowa, Iowa City, Iowa 52242, USA
    Am J Med Genet A 143:846-52. 2007
    ..Linkage and association analyses of these SNPs yield suggestive results for markers in FGFR1 (recessive multipoint HLOD 1.07) and BAG4 (recessive multipoint HLOD 1.31)...
  20. ncbi request reprint MSX1 and TGFB3 contribute to clefting in South America
    A R Vieira
    Departments of Pediatrics, 2613 JCP, University of Iowa, Iowa City, 52242 1083, USA
    J Dent Res 82:289-92. 2003
    ..These results suggest that MSX1 and TGFB3 mutations make a contribution to clefts in South American populations...
  21. ncbi request reprint Genetic origins in a South American clefting population
    A R Vieira
    Department of Pediatrics, University of Iowa, Iowa City 52242 1083, USA
    Clin Genet 62:458-63. 2002
    ..The implications of this finding include the possibility of using admixture mapping approaches to this population...
  22. ncbi request reprint Oral clefts and syndromic forms of tooth agenesis as models for genetics of isolated tooth agenesis
    A R Vieira
    Department of Pediatrics ML 2182, The University of Iowa, Iowa City, IA 52242, USA
    J Dent Res 82:162-5. 2003
    ..Oral clefts and syndromic forms of tooth agenesis may be the best models for isolated tooth agenesis. In the future, a precise description of the missing teeth in syndromes involving tooth agenesis may be useful...
  23. pmc Complete sequencing shows a role for MSX1 in non-syndromic cleft lip and palate
    P A Jezewski
    Department of Periodontics, College of Dentistry, University of Iowa, Iowa City 52242, USA
    J Med Genet 40:399-407. 2003
    ....
  24. ncbi request reprint Inheritance of cleft palate in South America: evidence for a major locus recessive
    A R Vieira
    Latin American Collaborative Study of Congenital Malformations ECLAMC, Department of Genetics, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil
    Orthod Craniofac Res 6:83-7. 2003
    ..Determine the model of inheritance of non-syndromic cleft palate in humans...
  25. pmc Genetic evidence for the role of loci at 19q13 in cleft lip and palate
    A Warrington
    J Med Genet 43:e26. 2006
    ..Clefts of the lip and palate are common birth defects, affecting approximately 1 in 700 births worldwide. The aetiology of clefting is complex, with multiple genetic and environmental influences...
  26. ncbi request reprint Candidate genes for nonsyndromic cleft lip and palate
    A R Vieira
    Department of Genetics, Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
    ASDC J Dent Child 68:272-9, 229. 2001
    ..These efforts are justified, however, because of the possibility of being able to predict more accurately the risk of such defects occurring...