Trinity Vera

Summary

Affiliation: University of Mississippi Medical Center
Country: USA

Publications

  1. pmc Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice
    Trinity Vera
    Dept of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi 39216 4505, USA
    Am J Physiol Regul Integr Comp Physiol 297:R738-43. 2009
  2. pmc Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells
    Silvia Kelsen
    Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216, USA
    Am J Physiol Renal Physiol 295:F1158-65. 2008
  3. pmc Moderate hyperbilirubinemia improves renal hemodynamics in ANG II-dependent hypertension
    Trinity Vera
    Dept of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, 39216 4505, USA
    Am J Physiol Regul Integr Comp Physiol 299:R1044-9. 2010
  4. pmc Blood pressure and renal blow flow responses in heme oxygenase-2 knockout mice
    David E Stec
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, Mississippi 39215, USA
    Am J Physiol Regul Integr Comp Physiol 297:R1822-8. 2009
  5. pmc Inhibition of biliverdin reductase increases ANG II-dependent superoxide levels in cultured renal tubular epithelial cells
    Shelby C Young
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
    Am J Physiol Regul Integr Comp Physiol 297:R1546-53. 2009
  6. pmc Kidney-specific induction of heme oxygenase-1 prevents angiotensin II hypertension
    Trinity Vera
    Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216 4505, USA
    Hypertension 52:660-5. 2008
  7. pmc Heme oxygenase-1 induction does not improve vascular relaxation in angiotensin II hypertensive mice
    David E Stec
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Mississippi, USA
    Am J Hypertens 21:189-93. 2008
  8. pmc Role of carbon monoxide in kidney function: is a little carbon monoxide good for the kidney?
    Eva Csongradi
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, MS 39216, USA
    Curr Pharm Biotechnol 13:819-26. 2012
  9. doi request reprint Role of carbon monoxide in blood pressure regulation
    David E Stec
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, MS 39216 4505, USA
    Hypertension 51:597-604. 2008
  10. ncbi request reprint Carbon monoxide (CO) protects renal tubular epithelial cells against cold-rewarm apoptosis
    David E Stec
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, Mississippi 39216 4505, USA
    Ren Fail 29:543-8. 2007

Collaborators

Detail Information

Publications16

  1. pmc Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice
    Trinity Vera
    Dept of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi 39216 4505, USA
    Am J Physiol Regul Integr Comp Physiol 297:R738-43. 2009
    ..These results indicate that moderate hyperbilirubinemia prevents ANG II-dependent hypertension by a mechanism that may involve decreases in vascular oxidative stress...
  2. pmc Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells
    Silvia Kelsen
    Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216, USA
    Am J Physiol Renal Physiol 295:F1158-65. 2008
    ..These results demonstrate that induction of HO-1 in mTALH cells reduces the levels of ANG II-mediated superoxide production through the production of both bilirubin and CO...
  3. pmc Moderate hyperbilirubinemia improves renal hemodynamics in ANG II-dependent hypertension
    Trinity Vera
    Dept of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, 39216 4505, USA
    Am J Physiol Regul Integr Comp Physiol 299:R1044-9. 2010
    ..These results indicate that improvement of renal hemodynamics may be one mechanism by which moderate hyperbilirubinemia lowers blood pressure in this model...
  4. pmc Blood pressure and renal blow flow responses in heme oxygenase-2 knockout mice
    David E Stec
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, Mississippi 39215, USA
    Am J Physiol Regul Integr Comp Physiol 297:R1822-8. 2009
    ..Our data indicate that blood pressure and RBF responses to increased ANG II or inhibition of nitric oxide are not significantly enhanced in HO-2 KO mice...
  5. pmc Inhibition of biliverdin reductase increases ANG II-dependent superoxide levels in cultured renal tubular epithelial cells
    Shelby C Young
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
    Am J Physiol Regul Integr Comp Physiol 297:R1546-53. 2009
    ....
  6. pmc Kidney-specific induction of heme oxygenase-1 prevents angiotensin II hypertension
    Trinity Vera
    Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216 4505, USA
    Hypertension 52:660-5. 2008
    ....
  7. pmc Heme oxygenase-1 induction does not improve vascular relaxation in angiotensin II hypertensive mice
    David E Stec
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Mississippi, USA
    Am J Hypertens 21:189-93. 2008
    ..However, the mechanism by which HO-1 lowers blood pressure in this model is not clear. This study was designed to determine whether induction of HO-1 results in an improvement in vascular relaxation in Ang II hypertensive mice...
  8. pmc Role of carbon monoxide in kidney function: is a little carbon monoxide good for the kidney?
    Eva Csongradi
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, MS 39216, USA
    Curr Pharm Biotechnol 13:819-26. 2012
    ....
  9. doi request reprint Role of carbon monoxide in blood pressure regulation
    David E Stec
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, MS 39216 4505, USA
    Hypertension 51:597-604. 2008
  10. ncbi request reprint Carbon monoxide (CO) protects renal tubular epithelial cells against cold-rewarm apoptosis
    David E Stec
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, Mississippi 39216 4505, USA
    Ren Fail 29:543-8. 2007
    ..cold-rewarm + CORM3 (100 microM) vs. cold-rewarm + HO-1 siRNA vs. cold-rewarm + CORM3 (100 microM) + HO-1 siRNA (n = 4). These results suggest that increased levels of CO alone can protect against cold-rewarm-induced apoptosis...
  11. ncbi request reprint HO-1 induction lowers blood pressure and superoxide production in the renal medulla of angiotensin II hypertensive mice
    Trinity Vera
    Department of Physiology and Biophysics, University of Mississippi Medical Center, 2500 North State St, Jackson, MS 39216 4505, USA
    Am J Physiol Regul Integr Comp Physiol 292:R1472-8. 2007
    ..These results suggest that reduction in superoxide and possibly hydrogen peroxide production in the renal medulla may be a potential mechanism by which induction of HO-1 with CoPP lowers blood pressure in ANG-II dependent hypertension...
  12. pmc In vivo inhibition of renal heme oxygenase with an imidazole-dioxolane inhibitor
    Eva Csongradi
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
    Pharmacol Res 61:525-30. 2010
    ..These inhibitors may be useful tools to elucidate the role of renal HO-1 in numerous physiologic and pathophysiologic conditions...
  13. ncbi request reprint Fenofibrate prevents the development of angiotensin II-dependent hypertension in mice
    Trinity Vera
    Department of Physiology and Biophysics, for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, Jackson, MS 39216 4505, USA
    Hypertension 45:730-5. 2005
    ..These results suggest that upregulation of the production of 20-HETE in renal tubules may contribute to the blood pressure-lowering effects of FF treatment in Ang II-dependent hypertension in C57BL/6J mice...
  14. ncbi request reprint Protective effect of carbon monoxide-releasing compounds in ischemia-induced acute renal failure
    Trinity Vera
    Department of Physiology and Biophysics, Center for Excellence in Cardiovascular Renal Research, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216 4505, USA
    J Am Soc Nephrol 16:950-8. 2005
    ..These results suggest that CO itself may be protective and limit renal damage in ischemia induced ARF...
  15. doi request reprint p66SHC-mediated mitochondrial dysfunction in renal proximal tubule cells during oxidative injury
    Istvan Arany
    Dept of Pediatrics, Div of Pediatric Nephrology, Univ of Mississippi Medical Center, 2500 N State St, Jackson, MS 39126, USA
    Am J Physiol Renal Physiol 298:F1214-21. 2010
    ..Thus, manipulating p66shc might offer a new therapeutic modality to ameliorate renal ischemic injury...
  16. pmc The Modulatory Role of Heme Oxygenase on Subpressor Angiotensin II-Induced Hypertension and Renal Injury
    Kiran Chandrashekar
    Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA
    Int J Hypertens 2012:392890. 2012
    ....