G V Velagaleti

Summary

Affiliation: University of Texas Medical Branch
Country: USA

Publications

  1. ncbi Patent ductus arteriosus and microdeletion 22q11 in a patient with Klinefelter syndrome
    G V Velagaleti
    Division of Genetics, Department of Pediatrics, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77551, USA
    Ann Genet 43:105-7. 2000
  2. ncbi A rapid and noninvasive method for detecting tissue-limited mosaicism: detection of i(12)(p10) in buccal smear from a child with Pallister-Killian syndrome
    Gopalrao V N Velagaleti
    Department of Pediatrics, University of Texas Medical Branch, Suite 3 350 Children s Hospital, 301 University Boulevard, Galveston, TX 77555, USA
    Genet Test 7:219-23. 2003
  3. ncbi Cytogenetic findings in a case of nodular fasciitis of subclavicular region
    Gopalrao V N Velagaleti
    Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA
    Cancer Genet Cytogenet 141:160-3. 2003
  4. ncbi Molecular cytogenetic characterization of a de novo unbalanced translocation leading to trisomy 17q25-->qter and monosomy 18p11.3-->pter in a girl with dysmorphic features
    Gopalrao V N Velagaleti
    Department of Pediatrics, University of Texas Medical Branch, Galveston, TX 77555, USA
    Clin Dysmorphol 12:29-33. 2003
  5. ncbi Subtelomeric rearrangements in idiopathic mental retardation
    Gopalrao V N Velagaleti
    Department of Pediatrics, University of Texas Medical Branch, Galveston, TX, USA
    Indian J Pediatr 72:679-85. 2005
  6. ncbi De novo supernumerary ring chromosome 7: first report of a non-mosaic patient and review of the literature
    G V N Velagaleti
    Departments of Pediatrics and Pathology, University of Texas Medical Branch, Galveston, TX USA
    Clin Genet 61:202-6. 2002
  7. ncbi Malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation (malignant triton tumor) with balanced t(7;9)(q11.2;p24) and unbalanced translocation der(16)t(1;16)(q23;q13)
    Gopalrao V N Velagaleti
    Department of Pediatrics, The University of Texas Medical Branch, Children s Hospital, Suite 3 350, 301 University Boulevard, Galveston, TX 77555, USA
    Cancer Genet Cytogenet 149:23-7. 2004
  8. ncbi Trisomy 5p. A case report and review
    G V Velagaleti
    Division of Genetics, Department of Pediatrics, Suite 3 350, Children s Hospital, 301 University Boulevard, TX 77555, Galveston, USA
    Ann Genet 43:143-5. 2000
  9. ncbi Trisomy 4 pter-q12 and monosomy of chromosome 13 pter-q12 in a male with deficiency of all blood lymphocyte populations
    G V Velagaleti
    Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas, USA
    Am J Med Genet 102:139-45. 2001
  10. ncbi Duplication 8 [inv dup(8)(p12p23)] with macrocephaly
    V S Tonk
    Department of Pediatrics, Texas Tech University Health Sciences Center, Lubbock, Texas, USA
    Ann Genet 44:195-9. 2001

Collaborators

  • Zoran Gatalica
  • S M Jalal
  • F C Schmalstieg
  • Susanna L Cooke
  • Derrick W Spell
  • Brynn Levy
  • A S Kulharya
  • R M Matalon
  • M Tarek Elghetany
  • M S Soloff
  • E A Jones
  • M Miettinen
  • Vijay S Tonk
  • Jill K Northup
  • V S Tonk
  • Lillian H Lockhart
  • Zhiqin Wang
  • James R Lupski
  • Judy C Hawkins
  • Gabriel A Bien-Willner
  • Jessica M Linhart
  • David L Morgan
  • Melissa M Blann
  • Jill K Tapper
  • V Sovani
  • Karen E Wain
  • Wendell W Tang
  • Yimin Ge
  • Hal K Hawkins
  • Swarupa A Gadre
  • Jill Northup
  • Mahmoud A Eltorky
  • Suimin Qiu
  • Neli Panova
  • J K Northup
  • Pawel Stankiewicz
  • Paweł Stankiewicz
  • Robert C Schutt
  • Svetlana A Yatsenko
  • Golder N Wilson
  • George R Saade
  • C A Jesurun
  • Marjorie R Grafe
  • X Huang
  • Jose Gonzalez
  • L H Lockhart
  • N Patel
  • Amantia Kennedy
  • M Kukolich
  • H E Wyandt
  • D L Morgan
  • Linda S Merryman
  • Rodolfo E Martinez
  • Hassan M Harirah
  • Phillip A Conlin
  • Shuliu Zhang
  • Neli I Panova
  • Alfredo B Gei
  • A S Knisely
  • E Filipowicz
  • G N Wilson

Detail Information

Publications30

  1. ncbi Patent ductus arteriosus and microdeletion 22q11 in a patient with Klinefelter syndrome
    G V Velagaleti
    Division of Genetics, Department of Pediatrics, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77551, USA
    Ann Genet 43:105-7. 2000
    ..2. While this finding may be coincidental, it is important to further evaluate patients when the clinical features are suggestive of a secondary abnormality...
  2. ncbi A rapid and noninvasive method for detecting tissue-limited mosaicism: detection of i(12)(p10) in buccal smear from a child with Pallister-Killian syndrome
    Gopalrao V N Velagaleti
    Department of Pediatrics, University of Texas Medical Branch, Suite 3 350 Children s Hospital, 301 University Boulevard, Galveston, TX 77555, USA
    Genet Test 7:219-23. 2003
    ..Using statistical analysis, we have also confirmed that the signal pattern in interphase nuclei is consistent with isochromosome 12p...
  3. ncbi Cytogenetic findings in a case of nodular fasciitis of subclavicular region
    Gopalrao V N Velagaleti
    Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA
    Cancer Genet Cytogenet 141:160-3. 2003
    ..TRKC is implicated in congenital fibrosarcoma, a benign proliferation of fibroblasts. The breakpoint and overexpression of the protein in our case further suggest a possible involvement of TRKC...
  4. ncbi Molecular cytogenetic characterization of a de novo unbalanced translocation leading to trisomy 17q25-->qter and monosomy 18p11.3-->pter in a girl with dysmorphic features
    Gopalrao V N Velagaleti
    Department of Pediatrics, University of Texas Medical Branch, Galveston, TX 77555, USA
    Clin Dysmorphol 12:29-33. 2003
    ..This case shows the importance of molecular cytogenetic techniques in detailed characterization of de novo chromosome rearrangements...
  5. ncbi Subtelomeric rearrangements in idiopathic mental retardation
    Gopalrao V N Velagaleti
    Department of Pediatrics, University of Texas Medical Branch, Galveston, TX, USA
    Indian J Pediatr 72:679-85. 2005
    ..To estimate the frequency of subtelomeric rearrangements in patients with sporadic and non-syndromic idiopathic mental retardation (IMR)...
  6. ncbi De novo supernumerary ring chromosome 7: first report of a non-mosaic patient and review of the literature
    G V N Velagaleti
    Departments of Pediatrics and Pathology, University of Texas Medical Branch, Galveston, TX USA
    Clin Genet 61:202-6. 2002
    ..All the published cases of ring chromosome 7, irrespective whether they are supernumerary or normal modal number, are mosaics except for one. The present subject is the first case of a de novo, non-mosaic supernumerary ring chromosome 7...
  7. ncbi Malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation (malignant triton tumor) with balanced t(7;9)(q11.2;p24) and unbalanced translocation der(16)t(1;16)(q23;q13)
    Gopalrao V N Velagaleti
    Department of Pediatrics, The University of Texas Medical Branch, Children s Hospital, Suite 3 350, 301 University Boulevard, Galveston, TX 77555, USA
    Cancer Genet Cytogenet 149:23-7. 2004
    ..This finding may relate to the observed poor prognostic outcome in this type of sarcoma. Also unique to our case is the translocation involving 7q and 9p, both regions may play a role in MPNST...
  8. ncbi Trisomy 5p. A case report and review
    G V Velagaleti
    Division of Genetics, Department of Pediatrics, Suite 3 350, Children s Hospital, 301 University Boulevard, TX 77555, Galveston, USA
    Ann Genet 43:143-5. 2000
    ..To date more than 40 patients with trisomy for various regions of short arm of chromosome 5 have been reported. Here we report a case with complete trisomy 5p and present a review of the literature...
  9. ncbi Trisomy 4 pter-q12 and monosomy of chromosome 13 pter-q12 in a male with deficiency of all blood lymphocyte populations
    G V Velagaleti
    Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas, USA
    Am J Med Genet 102:139-45. 2001
    ..A maternal granduncle with dissimilar dysmorphic features was not lymphopenic but was neutropenic...
  10. ncbi Duplication 8 [inv dup(8)(p12p23)] with macrocephaly
    V S Tonk
    Department of Pediatrics, Texas Tech University Health Sciences Center, Lubbock, Texas, USA
    Ann Genet 44:195-9. 2001
    ..Her findings, together with those of 37 reported cases with inv dup (8), define a syndrome that emphasizes the importance of genes on the 8p region for brain development...
  11. ncbi Ossifying fibromyxoid tumor of soft parts: report of a case with novel cytogenetic findings
    V Sovani
    Department of Pathology, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0359, USA
    Cancer Genet Cytogenet 127:1-6. 2001
    ..The karyotype was interpreted as 45,XY, der(6;14)(p10;q10),add(12)(q24.3). The chromosomal abnormalities suggest osteochondroblastic rather than neuronal or schwannian lineage...
  12. ncbi Molecular cytogenetic characterization of a familial der(1)del(1)(p36.33)dup(1)(p36.33p36.22) with variable phenotype
    Vijay S Tonk
    Department of Pediatrics, Texas Tech University, Lubbock, Texas, USA
    Am J Med Genet A 139:136-40. 2005
    ..Based on our results we suggest that the complex rearrangement seen in our family could be the result of the breakage-fusion-bridge (BFB) cycles model of formation...
  13. doi Fine mapping of breakpoints in two unrelated patients with rare overlapping interstitial deletions of 9q with mild dysmorphic features
    Anita S Kulharya
    Department of Pathology, Medical College of Georgia, Augusta, Georgia, USA
    Am J Med Genet A 146:2234-41. 2008
    ..Our study shows the investigative nature of the latest array technology and the limitations of this technology in the accurate delineation of breakpoints...
  14. ncbi Immortalization and characterization of human myometrial cells from term-pregnant patients using a telomerase expression vector
    Melvyn S Soloff
    Department of Obstetrics and GynecologySealy Center for Molecular Science, University of Texas Medical Branch, Galveston, TX 77555 1062, USA
    Mol Hum Reprod 10:685-95. 2004
    ..The immortalized cells should be useful for a range of studies, including high throughput analyses of the effects of environmental agents on the human myometrium...
  15. ncbi Do cytogenetic abnormalities precede morphologic abnormalities in a developing malignant condition?
    Jill K Northup
    Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA
    Eur J Haematol 78:152-6. 2007
    ..Therefore, the critical information needed for care of patients with malignant disorders may be incomplete or inaccurate if cytogenetic evaluation is overlooked...
  16. doi Molecular cytogenetic characterization of a unique and complex de novo 8p rearrangement
    Susanna L Cooke
    Department of Pathology, Cambridge University, Cambridge, UK
    Am J Med Genet A 146:1166-72. 2008
    ..Also unlike the inv dup del(8p), the phenotype in our case is milder with no central nervous system malformations or cardiac defects...
  17. ncbi Molecular cytogenetic characterization of a recombinant chromosome rec(22)dup(22q)inv(22)(p13q12.2)
    Vijay S Tonk
    Department of Pediatrics, Texas Tech University, Lubbock, Texas, USA
    Am J Med Genet A 124:92-5. 2004
    ..It is interesting that five of the seven patients with inv(22) come from Mexico, and four of the five patients from the Guadalajara region...
  18. doi First report of an interstitial deletion, del(5)(q33.1q35.1) in a girl with primary amenorrhea, seizures, and severe behavioral and developmental deficiencies
    Jill K Northup
    Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA
    Am J Med Genet A 146:2578-82. 2008
  19. ncbi Translocation (15;17) and trisomy 21 in the microgranular variant of acute promyelocytic leukemia
    Derrick W Spell
    Division of Hematology Oncology, Department of Internal Medicine, UTMB, 301 University Boulevard, Route 0565, Galveston, TX 77555, USA
    Cancer Genet Cytogenet 132:74-6. 2002
    ..The prognostic implications of trisomy 21 and other secondary cytogenetic aberrations in APL are reviewed. To our knowledge, this is the first reported case of trisomy 21 with t(15;17) in the microgranular variant of APL...
  20. ncbi Interstitial deletion of 20q in a patient with Waldenström macroglobulinemia following chemotherapy
    Melissa M Blann
    Department of Pathology, Texas Tech Medical Center, Lubbock, TX, USA
    Cancer Genet Cytogenet 132:145-8. 2002
    ..Interstitial deletions of 20q are known to occur in polycythemia vera and other hematological malignancies, especially those of myeloid origin...
  21. ncbi Prenatal diagnosis of a fetus with unbalanced translocation (4;13)(p16;q32) with overlapping features of Patau and Wolf-Hirschhorn syndromes
    Jill K Tapper
    Department of Pathology, University of Texas Medical Branch, Galveston, Tex, USA
    Fetal Diagn Ther 17:347-51. 2002
    ..She displayed overlapping features of both of these syndromes on ultrasound. To the best of our knowledge, this is the first report of a fetus with both partial trisomy 13 and deletion of 4p16, the critical region for WHS...
  22. ncbi Disease associated balanced chromosome rearrangements (DBCR): report of two new cases
    V S Tonk
    Department of Pediatrics, Texas Tech University Health Sciences Center, TX, Lubbock, USA
    Ann Genet 46:37-43. 2003
    ..Here, we report two new cases of apparently balanced de novo translocations resulting in developmental delay and dysmorphic features...
  23. ncbi Familial interstitial deletion of chromosome 4 (p15.2p16.1)
    Vijay S Tonk
    Departments of Pediatrics and Pathology, Texas Tech University, Lubbock, TX, USA
    Ann Genet 46:453-8. 2003
    ..This report of the familial transmission of del(4p) has wider implications in genetic counseling...
  24. pmc Position effects due to chromosome breakpoints that map approximately 900 Kb upstream and approximately 1.3 Mb downstream of SOX9 in two patients with campomelic dysplasia
    Gopalrao V N Velagaleti
    Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA
    Am J Hum Genet 76:652-62. 2005
    ..1 Mb upstream and 1.3 Mb downstream of it, respectively. The potential molecular mechanism responsible for the position effect is discussed...
  25. ncbi Interphase FISH screening for the LCR-mediated common rearrangement of isochromosome 17q in primary myelofibrosis
    Gabriel A Bien-Willner
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Am J Hematol 79:309-13. 2005
    ..2), discuss the potential prognostic value of this molecular diagnostic test, and examine the relevance of LCR-mediated NAHR to common rearrangements in neoplasms...
  26. ncbi Sonographic, pathologic and karyotypic findings in a rare case of placenta fenestrata
    Jessica M Linhart
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Tex, USA
    Fetal Diagn Ther 19:479-82. 2004
    ..This is the first reported case of placenta fenestrata diagnosed on ultrasound. In addition, this is also the first reported case of karyotype abnormality associated with abnormality of placental shape...
  27. ncbi Expression of CD4 on peripheral blood granulocytes. a novel finding in a case of myelodysplastic syndrome in association with t(5;12)
    M Tarek Elghetany
    Department of Pathology, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, USA
    Cancer Genet Cytogenet 136:38-42. 2002
    ..Since the breakpoint on chromosome 12 is near the CD4 gene, which is mapped to 12p12, we hypothesize that dysregulation of the CD4 gene may have occurred resulting in its persistent expression on mature and maturing granulocytes...
  28. ncbi Cytogenetic and molecular studies of an unusual case of multiple primary alveolar rhabdomyosarcomas: low-level chromosomal instability and reciprocal translocation t(6;11)
    Zhiqin Wang
    Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0588, USA
    Exp Mol Pathol 82:58-62. 2007
    ..The findings suggest that cytogenetic abnormalities of chromosome 6 may be associated with the development of early onset multiple ARMS in a subgroup of pediatric patients as seen in this case...
  29. ncbi Unique case of mosaicism involving two morphologically similar marker chromosomes of different centric origin in a patient with developmental delay
    Brynn Levy
    Department of Human Genetics, Mount Sinai School of Medicine, New York, New York, USA
    Am J Med Genet 108:198-204. 2002
    ..In light of our experience, we urge caution in interpreting karyotypes with marker chromosomes. Our case illustrates the limitations of fluorescent DNA probes and sampling errors...
  30. ncbi Concerning 14q(22) deletion in a familial case of anophthalmia with polydactyly
    Gopalrao V N Velagaleti
    Am J Med Genet A 126:108;author reply 110. 2004