G L Vega

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. pmc Metabolic risk susceptibility in men is partially related to adiponectin/leptin ratio
    Gloria Lena Vega
    Center for Human Nutrition and Departments of Clinical Nutrition, Internal Medicine and The Metabolic Unit of the Veterans Administration North Health Science Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390 9052, USA
    J Obes 2013:409679. 2013
  2. ncbi Management of atherogenic dyslipidemia of the metabolic syndrome: evolving rationale for combined drug therapy
    Gloria Lena Vega
    Department of Clinical Nutrition, Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas 75390 9052, USA
    Endocrinol Metab Clin North Am 33:525-44, vi. 2004
  3. ncbi Influence of extended-release nicotinic acid on nonesterified fatty acid flux in the metabolic syndrome with atherogenic dyslipidemia
    Gloria Lena Vega
    Center for Human Nutrition, University of Texas Southwestern Medical Center, and Veterans Affair Medical Center, Dallas, Texas 75390 9052, USA
    Am J Cardiol 95:1309-13. 2005
  4. doi Prevalence of the metabolic syndrome as influenced by the measure of obesity employed
    Gloria Lena Vega
    Departments of Clinical Nutrition, Internal Medicine, and Clinical Science and Center for Human Nutrition and Clinical and Translational Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Am J Cardiol 105:1306-12. 2010
  5. doi Impaired hepatic ketogenesis in moderately obese men with hypertriglyceridemia
    Gloria Lena Vega
    Department of Clinical Nutrition, Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, TX 75390 9052, USA
    J Investig Med 57:590-4. 2009
  6. ncbi Metabolic correlates of nonalcoholic fatty liver in women and men
    Gloria Lena Vega
    The Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9052, USA
    Hepatology 46:716-22. 2007
  7. doi Oxandrolone enhances hepatic ketogenesis in adult men
    Gloria Lena Vega
    Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Investig Med 56:920-4. 2008
  8. ncbi Plasma 24S hydroxycholesterol response to statins in Alzheimer's disease patients: effects of gender, CYP46, and ApoE polymorphisms
    Gloria Lena Vega
    The Nutrition and Metabolism Laboratory, Metabolic Unit, Veterans Affairs Medical Center, Dallas, TX 75390, USA
    J Mol Neurosci 33:51-5. 2007
  9. doi Effects of N-3 fatty acids on hepatic triglyceride content in humans
    Gloria Lena Vega
    Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, TX 75390 9052, USA
    J Investig Med 56:780-5. 2008
  10. ncbi Obesity and the metabolic syndrome
    G L Vega
    Department of Clinical Nutrition, University of Texas, Southwestern Medical Center, Dallas, TX, USA
    Minerva Endocrinol 29:47-54. 2004

Detail Information

Publications32

  1. pmc Metabolic risk susceptibility in men is partially related to adiponectin/leptin ratio
    Gloria Lena Vega
    Center for Human Nutrition and Departments of Clinical Nutrition, Internal Medicine and The Metabolic Unit of the Veterans Administration North Health Science Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390 9052, USA
    J Obes 2013:409679. 2013
    ..High adiponectin/leptin ratio may be protective from metabolic risks imparted by high triglyceride, low HDL, and insulin resistance...
  2. ncbi Management of atherogenic dyslipidemia of the metabolic syndrome: evolving rationale for combined drug therapy
    Gloria Lena Vega
    Department of Clinical Nutrition, Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas 75390 9052, USA
    Endocrinol Metab Clin North Am 33:525-44, vi. 2004
    ....
  3. ncbi Influence of extended-release nicotinic acid on nonesterified fatty acid flux in the metabolic syndrome with atherogenic dyslipidemia
    Gloria Lena Vega
    Center for Human Nutrition, University of Texas Southwestern Medical Center, and Veterans Affair Medical Center, Dallas, Texas 75390 9052, USA
    Am J Cardiol 95:1309-13. 2005
    ....
  4. doi Prevalence of the metabolic syndrome as influenced by the measure of obesity employed
    Gloria Lena Vega
    Departments of Clinical Nutrition, Internal Medicine, and Clinical Science and Center for Human Nutrition and Clinical and Translational Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Am J Cardiol 105:1306-12. 2010
    ..In conclusion, abridged ATP III MS appears to be preferable to ATP III MS for the detection of candidates for intensive cardiovascular risk reduction...
  5. doi Impaired hepatic ketogenesis in moderately obese men with hypertriglyceridemia
    Gloria Lena Vega
    Department of Clinical Nutrition, Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, TX 75390 9052, USA
    J Investig Med 57:590-4. 2009
    ..Several studies suggest that increased nonesterified fatty acid flux and increased de novo lipogenesis may contribute to hypertriglyceridemia, but few studies have examined fatty acid oxidation as a factor...
  6. ncbi Metabolic correlates of nonalcoholic fatty liver in women and men
    Gloria Lena Vega
    The Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9052, USA
    Hepatology 46:716-22. 2007
    ..Obese subjects with hepatic steatosis had higher ratios of truncal-to-lower body fat and other indicators of adipose tissue dysfunction compared with obese subjects without steatosis...
  7. doi Oxandrolone enhances hepatic ketogenesis in adult men
    Gloria Lena Vega
    Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Investig Med 56:920-4. 2008
    ..Immediate administration of oxandrolone markedly increases hepatic lipase activity and reduces levels of plasma high-density lipoprotein...
  8. ncbi Plasma 24S hydroxycholesterol response to statins in Alzheimer's disease patients: effects of gender, CYP46, and ApoE polymorphisms
    Gloria Lena Vega
    The Nutrition and Metabolism Laboratory, Metabolic Unit, Veterans Affairs Medical Center, Dallas, TX 75390, USA
    J Mol Neurosci 33:51-5. 2007
    ..There were no untoward effects of the standard doses of statin for the duration of treatment. Statins are currently in trial to determine their effect on the course of AD...
  9. doi Effects of N-3 fatty acids on hepatic triglyceride content in humans
    Gloria Lena Vega
    Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, TX 75390 9052, USA
    J Investig Med 56:780-5. 2008
    ..Because dietary N-3 fatty acids reduce plasma triglycerides, they may also decrease hepatic triglyceride content. If so, N-3 fatty acids might constitute a therapy for fatty liver...
  10. ncbi Obesity and the metabolic syndrome
    G L Vega
    Department of Clinical Nutrition, University of Texas, Southwestern Medical Center, Dallas, TX, USA
    Minerva Endocrinol 29:47-54. 2004
    ..Therefore, the metabolic alterations commonly associated with increased central obesity of the metabolic syndrome are pro-atherogenic partly because the metabolites are proinflammatory...
  11. ncbi Free fatty acid metabolism during fenofibrate treatment of the metabolic syndrome
    Gloria Lena Vega
    Department of Clinical Nutrition, and Center for Human Nutrition, University of Texas Southwest Medical Center, and Metabolic Unit, Veterans Affairs Medical Center, Dallas, Texas 75390 9052, USA
    Clin Pharmacol Ther 74:236-44. 2003
    ..Our objective was to determine whether fenofibrate modifies the metabolism of nonesterified (free) fatty acids as a component of its triglyceride-lowering action in male patients with the metabolic syndrome...
  12. ncbi Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease
    Gloria Lena Vega
    Department of Clinical Nutrition, The Center for Human Nutrition, University of Texas Southwestern Medical Center and Nutrition and Metabolism Laboratory, Veterans Affairs Medical Center, Dallas 75390, USA
    Arch Neurol 60:510-5. 2003
    ..Most of plasma 24S-hydroxycholesterol is derived from brain cholesterol; consequently, plasma levels of the oxysterol reflect brain cholesterol catabolism...
  13. ncbi Effects of adding fenofibrate (200 mg/day) to simvastatin (10 mg/day) in patients with combined hyperlipidemia and metabolic syndrome
    Gloria Lena Vega
    The Center for Human Nutrition, Department of Clinical Nutrition, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9052, USA
    Am J Cardiol 91:956-60. 2003
    ..Therefore, a combination of simvastatin 10 mg/day and fenofibrate 200 mg/day appears to be effective and safe for the treatment of atherogenic dyslipidemia in combined hyperlipidemia...
  14. doi Effect of colesevelam hydrochloride on glycemia and insulin sensitivity in men with the metabolic syndrome
    Gloria Lena Vega
    The Metabolic Unit, Lipid, and Diabetes Clinics of the Veterans Affairs North Health Care System, Dallas, Texas, USA
    Am J Cardiol 108:1129-35. 2011
    ..Finally, an increase in triglycerides with colesevelam therapy might have been related to a lesser suppression of nonesterified fatty acids levels in the postprandial state...
  15. ncbi Cardiovascular outcomes for obesity and metabolic syndrome
    Gloria Lena Vega
    Department of Clinical Nutrition, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9052, USA
    Obes Res 10:27S-32S. 2002
  16. ncbi Efficacy, safety, and tolerability of once-daily niacin for the treatment of dyslipidemia associated with type 2 diabetes: results of the assessment of diabetes control and evaluation of the efficacy of niaspan trial
    Scott M Grundy
    The University of Texas Southwestern Medical Center, Room Y3206, 5323 Harry Hines Blvd, Dallas, TX 75390 9052
    Arch Intern Med 162:1568-76. 2002
    ..We evaluated the efficacy and safety of once-daily extended-release (ER) niacin in patients with diabetic dyslipidemia...
  17. ncbi Effect of lifibrol on the metabolism of low density lipoproteins and cholesterol
    G L Vega
    Department of Clinical Nutrition, University of Texas Southwestern Medical Center, Dallas, USA
    J Intern Med 246:1-9. 1999
    ..This finding raises the possibility that lifibrol activates the LDL-receptor pathway through a different mechanisms which remains to be determined...
  18. ncbi Correlation of statin-increased platelet APP ratios and reduced blood lipids in AD patients
    F Baskin
    Department of Neurology, University of Texas Southwestern Medical Center at Dallas, TX 75390 9036, USA
    Neurology 60:2006-7. 2003
    ..APP ratios increased [t(37) = -3.888, p = 0.0004], proportionally with reduced cholesterol [r(36) = -0.45, p = 0.005]. Longer trials may reveal slowed cognitive loss, validating this index...
  19. doi Adipose tissue mass and location affect circulating adiponectin levels
    A T Turer
    Department of Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 8521, USA
    Diabetologia 54:2515-24. 2011
    ..Plasma levels of adiponectin are inversely associated with body mass. We hypothesised that adipose tissue distribution and body composition influences adiponectin levels...
  20. ncbi Effects of combined therapy with lovastatin and colestipol in heterozygous familial hypercholesterolemia. Effects on kinetics of apolipoprotein B
    G L Vega
    Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas 75235
    Arteriosclerosis 9:I135-44. 1989
    ....
  21. doi Correlation of non-high-density lipoprotein cholesterol and low-density lipoprotein cholesterol with apolipoprotein B during simvastatin + fenofibrate therapy in patients with combined hyperlipidemia (a subanalysis of the SAFARI trial)
    Scott M Grundy
    University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Am J Cardiol 104:548-53. 2009
    ....
  22. ncbi The effects of gender and CYP46 and apo E polymorphism on 24S-hydroxycholesterol levels in Alzheimer's patients treated with statins
    Gloria Lena Vega
    Department of Clinical Nutrition, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9052, USA
    Curr Alzheimer Res 1:71-7. 2004
    ..Polymorphisms of CYP46 or apo E do not explain levels of oxysterol or non-HDL cholesterol or the responsiveness to statin treatment in this study...
  23. pmc Variable contributions of fat content and distribution to metabolic syndrome risk factors
    Scott M Grundy
    Donald W Reynolds Cardiovascular Clinical Research Center, Department of Internal Medicine, Center for Human Nutrition, Dallas, Texas 75390 9052, USA
    Metab Syndr Relat Disord 6:281-8. 2008
    ..However, the relative contributions of these two different parameters of body fat to the various components of the metabolic syndrome have not been well defined...
  24. ncbi Hepatic lipase: new insights from genetic and metabolic studies
    J C Cohen
    Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, USA
    Curr Opin Lipidol 10:259-67. 1999
    ..Association studies using these polymorphisms are elucidating the effects of variation in hepatic lipase activity on plasma lipoprotein concentrations and susceptibility to coronary atherosclerosis...
  25. ncbi Variability in postheparin hepatic lipase activity is associated with plasma adiponectin levels in African Americans
    Jacob J Clarenbach
    Center for Human Nutrition, Donald W Reynolds Cardiovascular Clinical Research Center of the University of Texas Southwestern Medical Center and Metabolic Unit, Veterans Affairs Medical Center, Dallas, TX, USA
    J Investig Med 55:187-94. 2007
    ..The higher than expected HDL-C levels are usually attributed to low levels of hepatic triglyceride lipase (HTGL) activity. Factors that regulate HTGL in African Americans are not well delineated...
  26. ncbi Tumor necrosis factor mediates hypertriglyceridemia during thermal injury in mice genetically susceptible to lipopolysaccharides
    G L Vega
    Department of Clinical Nutrition, University of Texas Southwestern Medical Center, Dallas 75235 9052
    J Burn Care Rehabil 12:463-7. 1991
    ..This is the first report that demonstrates that hypertriglyceridemia that is secondary to thermal injury is induced by tumor necrosis factor...
  27. ncbi Relationship of apolipoprotein B levels to the number of risk factors for metabolic syndrome
    Jacob J Clarenbach
    Center for Human Nutrition, the Donald W Reynolds Cardiovascular Research Center of the University of Texas Southwestern Medical Center at Dallas, TX 75390 9052, USA
    J Investig Med 55:237-47. 2007
    ..Non-HDL-C correlates highly with total apo B in patients with metabolic syndrome and had advantages as a target of therapy over LDL-C or NMR apo B...
  28. ncbi Influence of body fat content and distribution on variation in metabolic risk
    Gloria Lena Vega
    Donald W Reynolds Cardiovascular Clinical Research Center and Department of Internal Medicine, Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9052, USA
    J Clin Endocrinol Metab 91:4459-66. 2006
    ..The objective of the study was to determine whether this can be confirmed and generalized throughout the population...
  29. ncbi Responsiveness of plasma lipids and lipoproteins to plant stanol esters
    Nilo B Cater
    Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9052, USA
    Am J Cardiol 96:23D-28D. 2005
    ..This makes plant stanols an attractive dietary component to help to achieve the goals of LDL-lowering therapy in patients requiring an LDL-lowering drug...
  30. ncbi Ten-year risk of cardiovascular incidence related to diabetes, prediabetes, and the metabolic syndrome
    Jing Liu
    Capital Medical University attached Beijing Anzhen Hospital, Beijing, China
    Am Heart J 153:552-8. 2007
    ..We aimed to compare MetS with dysglycemia in their association with the 10-year incidence risk of CVD...
  31. ncbi Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group IV: lifestyle and medical management of risk factors
    Scott M Grundy
    Circulation 105:e153-8. 2002
  32. ncbi Ethnic-specific criteria for the metabolic syndrome: evidence from China
    Jing Liu
    Department of Epidemiology, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Capital University of Medical Sciences attached Beijing Anzhen Hospital, Beijing 100029, China
    Diabetes Care 29:1414-6. 2006